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Dermatology

Guideline | Onychomycosis

1 Jun, 2023 | 12:01h | UTC

Guideline onychomycosis – Journal of the German Society of Dermatology

 


Consensus Paper | Safe skin, safe patients: the value of patient hygiene

31 May, 2023 | 14:06h | UTC

Safe Skin, Safe Patients: The Value of Patient Hygiene – Clinical Consensus Statement – American Journal of Nursing (free for a limited period)

 


SR | Efficacy of negative pressure wound therapy in treating pressure ulcers remains uncertain

31 May, 2023 | 13:53h | UTC

Negative pressure wound therapy for treating pressure ulcers – Cochrane Library

Summary: Negative pressure wound therapy for treating pressure ulcers – Cochrane Library

 


RCT | Microdosed incisional clindamycin reduces infection rate in skin cancer surgery

30 May, 2023 | 12:03h | UTC

Effect of Microdoses of Incisional Antibiotics on the Rate of Surgical Site Infections in Skin Cancer Surgery: A Randomized Clinical Trial – JAMA Surgery (link to abstract – $ for full-text)

See also: Visual Abstract

Commentary: Microdosed Incisional Clindamycin Cuts SSI After Skin Cancer Surgery – HealthDay

 


Acute generalized exanthematous pustulosis: clinical features, differential diagnosis, and management

29 May, 2023 | 10:54h | UTC

Acute Generalized Exanthematous Pustulosis: Clinical Features, Differential Diagnosis, and Management – American Journal of Clinical Dermatology

 


MASCC Guidelines for the prevention and management of acute radiation dermatitis | Part 1 – Systematic review

29 May, 2023 | 10:53h | UTC

MASCC clinical practice guidelines for the prevention and management of acute radiation dermatitis: part 1) systematic review – eClinicalMedicine

Related:

RCT | Bacterial decolonization for prevention of radiation dermatitis

RCT | Mepitel film for the prevention of acute radiation dermatitis in breast cancer.

 


Review | Skin assessments and interventions for maintaining skin integrity in nursing practice

25 May, 2023 | 11:25h | UTC

Skin assessments and interventions for maintaining skin integrity in nursing practice: An umbrella review – International Journal of Nursing Studies

 


Guidelines on the diagnosis and treatment of foot infection in persons with diabetes

24 May, 2023 | 13:30h | UTC

Guidelines on the diagnosis and treatment of foot infection in persons with diabetes – International Working Group on the Diabetic Foot

 


RCT | Spironolactone enhances acne outcomes and offers a viable alternative to oral antibiotics

24 May, 2023 | 13:27h | UTC

Summary: The SAFA (Spironolactone for Adult Female Acne) trial was a multicenter, phase 3, double-blind, randomized controlled trial in England and Wales and evaluated the efficacy of spironolactone for treating adult women with acne vulgaris. A total of 410 women, aged ≥18 years and suffering from facial acne for a minimum of six months, were randomly assigned to receive either 50 mg/day of spironolactone or a placebo, increasing to 100 mg/day until week 24.

The primary outcome was measured by the Acne-Specific Quality of Life (Acne-QoL) symptom subscale score at week 12 and 24. The trial demonstrated that spironolactone improved Acne-QoL scores more effectively than the placebo, particularly at week 24. Additionally, more participants in the spironolactone group reported acne improvement, and treatment success was significantly higher in this group at week 12. Mild side effects, notably headaches, were more common in the spironolactone group.

The findings from the SAFA trial highlight spironolactone’s effectiveness, safety, and tolerability in treating adult women with acne vulgaris, suggesting it is a viable alternative to long-term antibiotic treatments. Future research is proposed on higher initial dosages of spironolactone, and its effects on different subgroups like patients with different ages, body mass index, and ethnicity.

Article: Effectiveness of spironolactone for women with acne vulgaris (SAFA) in England and Wales: pragmatic, multicentre, phase 3, double blind, randomised controlled trial – The BMJ

Editorial: What do we know about prescribing spironolactone for acne? – The BMJ

News Release: Non-antibiotic treatment for women with persistent acne shown to be effective – University of Southhampton

 


Cohort Study | 5-mm margins may be adequate for T1a melanoma excision near critical structures

16 May, 2023 | 14:40h | UTC

Association of Excision Margin Size With Local Recurrence and Survival in Patients With T1a Melanoma at Critical Structures – JAMA Dermatology (link to abstract – $ for full-text)

Commentary: Melanoma Excisions with 5 Millimeter Margins Linked to Less Risk of Local Recurrence – HCP Live

 

Commentary on Twitter

 


The impact of hyperhidrosis on quality of life: a review of the literature

16 May, 2023 | 14:33h | UTC

The Impact of Hyperhidrosis on Quality of Life: A Review of the Literature – American Journal of Clinical Dermatology

 


Cutaneous Lupus Erythematosus | An update on pathogenesis and future therapeutic directions

12 May, 2023 | 13:28h | UTC

Cutaneous Lupus Erythematosus: An Update on Pathogenesis and Future Therapeutic Directions – American Journal of Clinical Dermatology

 


RCT | Bacterial decolonization for prevention of radiation dermatitis

8 May, 2023 | 12:46h | UTC

Bacterial Decolonization for Prevention of Radiation Dermatitis: A Randomized Clinical Trial – JAMA Oncology (free for a limited period)

News Release: A Simple Antibacterial Treatment Solves a Severe Skin Problem Caused by Radiation Therapy – Montefiore Einstein Cancer Center

 

Commentary on Twitter

 


Cohort Study | Skin biopsy yields 88% sensitivity in detecting meningococcal Purpura Fulminans

5 May, 2023 | 15:15h | UTC

Skin biopsy in adult patients with meningococcal purpura fulminans: a multicenter retrospective cohort study – Critical Care

 


Review | A practical guide to hidradenitis suppurativa

4 May, 2023 | 13:29h | UTC

A practical guide to hidradenitis suppurativa – Family Practice

 


Differential diagnosis, prevention, and treatment of mpox (Monkeypox): a review for dermatologists

3 May, 2023 | 15:27h | UTC

Differential Diagnosis, Prevention, and Treatment of mpox (Monkeypox): A Review for Dermatologists – American Journal of Clinical Dermatology

Related: Supportive Care Management Recommendations for Mucocutaneous Manifestations of Monkeypox Infection – Mayo Clinic Proceedings

 


Supportive care management recommendations for mucocutaneous manifestations of monkeypox infection

3 May, 2023 | 15:26h | UTC

Supportive Care Management Recommendations for Mucocutaneous Manifestations of Monkeypox Infection – Mayo Clinic Proceedings

Related: Differential Diagnosis, Prevention, and Treatment of mpox (Monkeypox): A Review for Dermatologists – American Journal of Clinical Dermatology

 


Review | Calciphylaxis and kidney disease

3 May, 2023 | 15:20h | UTC

Calciphylaxis and Kidney Disease: A Review – American Journal of Kidney Diseases

 


RCT | Efficacy and safety of tralokinumab in adolescents with moderate to severe atopic dermatitis

3 May, 2023 | 15:04h | UTC

Efficacy and Safety of Tralokinumab in Adolescents With Moderate to Severe Atopic Dermatitis: The Phase 3 ECZTRA 6 Randomized Clinical Trial – JAMA Dermatology

Commentary: Tralokinumab Efficacious, Well-Tolerated for Adolescents with Atopic Dermatitis – HCP Live

 

Commentary on Twitter

 


Syphilis in dermatology | Recognition and management

2 May, 2023 | 13:40h | UTC

Syphilis in Dermatology: Recognition and Management – American Journal of Clinical Dermatology

 

Commentary on Twitter

 


USPSTF Statement | There is insufficient evidence to guide skin cancer screening recommendations

24 Apr, 2023 | 14:07h | UTC

Screening for Skin Cancer: US Preventive Services Task Force Recommendation Statement – JAMA

Evidence Report: Skin Cancer Screening: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Editorials:

The USPSTF I Statement on Skin Cancer Screening—Not a Disappointment but an Opportunity – JAMA Dermatology

Skin Cancer Screening: The Importance of Identifying High-risk Subgroups and the Need for US-Based Population Research – JAMA

Insufficient Evidence for Screening Reinforces Need for Primary Prevention of Skin Cancer – JAMA Internal Medicine

Patient Page: Screening and Prevention of Skin Cancer – JAMA

Author Interview: USPSTF Recommendation: Screening for Skin Cancer – JAMA

 

Commentary on Twitter

 


RCT | Efficacy and safety of ritlecitinib in adults and adolescents with alopecia areata

21 Apr, 2023 | 13:00h | UTC

Efficacy and safety of ritlecitinib in adults and adolescents with alopecia areata: a randomised, double-blind, multicentre, phase 2b–3 trial – The Lancet (link to abstract – $ for full-text)

News Release: Progress in search for alopecia areata treatment for adolescents  – Yale News

 

Commentary on Twitter

 


Podcast | Fungi fun! an in-depth look at tinea infections in children

18 Apr, 2023 | 13:14h | UTC

Fungi Fun! An In-Depth Look at Tinea Infections – The Cribsiders

 


Phase 2 RCT | Dersimelagon in erythropoietic protoporphyrias

17 Apr, 2023 | 13:05h | UTC

Dersimelagon in Erythropoietic Protoporphyrias – News England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 


RCTs | Eczema Care Online behavioral interventions may support self-care for children and young people

12 Apr, 2023 | 13:02h | UTC

Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials – The BMJ

Editorial: How to make Eczema Care Online freely available – The BMJ

News Release: New website helps improve eczema in children and young people – University of Southampton

 


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