Dermatology | Links Medicus Content Curation & Alerts in Medicine

Consensus Paper | Management of pemphigus

20 Jan, 2023 | 14:39h | UTC

Taiwanese dermatological association (TDA) consensus for the management of pemphigus – Journal of the Formosan Medical Association

Consensus Paper | Revision of classification system for reporting on skin biopsies of melanocytic lesions

15 Jan, 2023 | 20:17h | UTC

Revision of the Melanocytic Pathology Assessment Tool and Hierarchy for Diagnosis Classification Schema for Melanocytic Lesions: A Consensus Statement – JAMA Network Open

Commentaries:

Classification system for reporting on skin biopsies of melanocytic lesions – University of California – Los Angeles Health Sciences

MPATH-Dx Version 2.0 Simplifies Classification of Melanoma – HealthDay

Commentary on Twitter

American and international #dermatopathologists revise Melanocytic Pathology Assessment Tool and Hierarchy for Diagnosis schema. MPATH-Dx V2.0 improves standardized diagnostic reporting and patient management of #melanoma. https://t.co/G0fluzq5fs

— JAMA Network Open (@JAMANetworkOpen) January 12, 2023

RCT | Lebrikizumab in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis

15 Jan, 2023 | 20:07h | UTC

Efficacy and Safety of Lebrikizumab in Combination With Topical Corticosteroids in Adolescents and Adults With Moderate-to-Severe Atopic Dermatitis: A Randomized Clinical Trial (ADhere) – JAMA Dermatology

Commentary on Twitter

Does blocking the IL-13 cytokine w/ lebrikizumab combined w/ topical therapy provide clinical benefit in atopic eczema? This study reflecting real-world use patterns suggests a benefit. https://t.co/apUvYO3Jqv

— JAMA Dermatology (@JAMADerm) January 13, 2023

Retrospective Study | Clinical features and management of individuals admitted to hospital with monkeypox

13 Jan, 2023 | 13:33h | UTC

Clinical features and management of individuals admitted to hospital with monkeypox and associated complications across the UK: a retrospective cohort study – The Lancet Infectious Diseases

Monkeypox (hMPXV infection): a practical review

11 Jan, 2023 | 14:25h | UTC

Monkeypox (hMPXV infection): A practical review – American Journal of Medicine

WHO Interim Guidance | Surveillance, case investigation and contact tracing for mpox (monkeypox)

10 Jan, 2023 | 14:45h | UTC

Surveillance, case investigation and contact tracing for mpox (monkeypox): interim guidance, 22 December 2022 – World Health Organization

Atypical ulcers: a stepwise approach for clinicians

10 Jan, 2023 | 14:00h | UTC

Atypical Ulcers: A Stepwise Approach for Clinicians – Wounds

Intrapatient RCT | Beremagene Geperpavec (B-VEC) vs. placebo for dystrophic epidermolysis bullosa.

16 Dec, 2022 | 13:34h | UTC

Trial of Beremagene Geperpavec (B-VEC) for Dystrophic Epidermolysis Bullosa – New England Journal of Medicine (link to abstract – $ for full-text)

RCT | Mepitel film for the prevention of acute radiation dermatitis in breast cancer.

12 Dec, 2022 | 12:40h | UTC

Mepitel Film for the Prevention of Acute Radiation Dermatitis in Breast Cancer: A Randomized Multicenter Open-Label Phase III Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)

SR | Skin care interventions in infants for preventing eczema and food allergy.

12 Dec, 2022 | 12:23h | UTC

Skin care interventions in infants for preventing eczema and food allergy – Cochrane Library

Summary: Skin care interventions for preventing eczema and food allergy – Cochrane Library

Commentary on Twitter

Read our newest review on skin care interventions in infants for preventing eczema and food allergy! https://t.co/o8HtBXRVM5 pic.twitter.com/BPzsjJZvTf

— Cochrane Skin (@CochraneSkin) November 15, 2022

M-A | Allergen immunotherapy for atopic dermatitis.

9 Dec, 2022 | 13:24h | UTC

Allergen immunotherapy for atopic dermatitis: Systematic review and meta-analysis of benefits and harms – The Journal of Allergy and Clinical Immunology

Cohort Study | Cutaneous involvement in catastrophic antiphospholipid syndrome.

8 Dec, 2022 | 12:53h | UTC

Cutaneous Involvement in Catastrophic Antiphospholipid Syndrome in a Multicenter Cohort of 65 Patients – JAMA Dermatology (free for a limited period)

Commentary on Twitter

In this cohort study, half of patients with catastrophic APS (CAPS) showed cutaneous involvement, with a spectrum of clinical presentations, including distal inflammatory edema. Skin biopsies confirmed diagnosis in all but 1 biopsied patient. https://t.co/lwBL3lyLxT

— JAMA Dermatology (@JAMADerm) December 7, 2022

RCT | Bimekizumab in patients with psoriatic arthritis, naive to biologic treatment.

7 Dec, 2022 | 14:29h | UTC

Bimekizumab in patients with psoriatic arthritis, naive to biologic treatment: a randomised, double-blind, placebo-controlled, phase 3 trial (BE OPTIMAL) – The Lancet

Monkeypox in pregnancy: virology, clinical presentation, and obstetric management.

6 Dec, 2022 | 13:58h | UTC

Monkeypox in pregnancy: virology, clinical presentation, and obstetric management – American Journal of Obstetrics & Gynecology

WHO renames “monkeypox” as “mpox” to help destigmatize the disease.

Monkeypox – The Lancet

Study shows there is substantial monkeypox transmission before symptoms appear.

Global monkeypox case hospitalisation rates: A rapid systematic review and meta-analysis – eClinicalMedicine

Human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks: a global case series – The Lancet

Monkeypox — A Sobering Sentinel for Pandemic Preparedness and Sexual Health System Capacity – New England Journal of Medicine

CDC study shows healthcare workers have a low risk of infection after exposure to patients with monkeypox.

Monkeypox – New England Journal of Medicine

Diagnosis and Management of Monkeypox: A Review for the Emergency Clinician – Annals of Emergency Medicine

Monkeypox: disease epidemiology, host immunity and clinical interventions.

Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health

Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain.

CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.

Update on the Monkeypox Outbreak – JAMA

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

WHO renames “monkeypox” as “mpox” to help destigmatize the disease.

29 Nov, 2022 | 14:27h | UTC

WHO recommends new name for monkeypox disease – World Health Organization

Commentaries:

WHO to phase out the name ‘monkeypox’ for ‘mpox’ – STAT

WHO renames monkeypox as mpox, citing racist stigma – NPR

The Future of Monkeypox – The Atlantic

Monkeypox given new name by global health experts – BBC

Monkeypox to be renamed mpox to avoid stigma, says WHO – The Guardian

Commentary on Twitter (thread – click for more)

Following consultations, WHO will begin using a new term for “#monkeypox” disease: '#mpox'.
Both names will be used simultaneously for one year while 'monkeypox' is phased out https://t.co/VT9DAdYrGY pic.twitter.com/Ae6zgkefPI

— World Health Organization (WHO) (@WHO) November 28, 2022

Seminar | Monkeypox.

27 Nov, 2022 | 22:29h | UTC

Monkeypox – The Lancet

Commentaries:

Study shows there is substantial monkeypox transmission before symptoms appear.

Global monkeypox case hospitalisation rates: A rapid systematic review and meta-analysis – eClinicalMedicine

Human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks: a global case series – The Lancet

Monkeypox — A Sobering Sentinel for Pandemic Preparedness and Sexual Health System Capacity – New England Journal of Medicine

CDC study shows healthcare workers have a low risk of infection after exposure to patients with monkeypox.

Monkeypox – New England Journal of Medicine

Diagnosis and Management of Monkeypox: A Review for the Emergency Clinician – Annals of Emergency Medicine

Monkeypox: disease epidemiology, host immunity and clinical interventions.

Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health

Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain.

CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.

Update on the Monkeypox Outbreak – JAMA

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

Commentary on Twitter

Seminar: Monkeypox

In light of the 2022 global outbreak, @oriolmitja and colleagues provide an overview of epidemiology, clinical presentation, treatment, prevention, and more.

📌 https://t.co/gB0fcokA8D pic.twitter.com/Db3ZsU4ykt

— The Lancet (@TheLancet) November 22, 2022

Improving antimicrobial stewardship with penicillin allergy testing: a review of current practices and unmet needs.

27 Nov, 2022 | 22:25h | UTC

Improving antimicrobial stewardship with penicillin allergy testing: a review of current practices and unmet needs – JAC-Antimicrobial Resistance

Management of Patients with Suspected or Confirmed Antibiotic Allergy. Executive Summary of Guidance from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Society of Allergy and Clinical Immunology (SEAIC), the Spanish Society of Hospital Pharmacy (SEFH) and the Spanish Society of Intensive Medicine and Coronary Care Units (SEMICYUC) – Journal of Investigational Allergology and Clinical Immunology (PDF)

The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.

M-A: Most patients with allergy to Penicillin can be given Cefazolin

Systematic review: Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge

Penicillin allergy labels increase second-line broad-spectrum antibiotic prescribing for pediatric respiratory tract infections

Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy

Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule

Management of a surgical patient with a label of penicillin allergy: narrative review and consensus recommendations – British Journal of Anaesthesia

NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk

Cohort Study: Risk of Meticillin Resistant Staphylococcus Aureus and Clostridium Difficile in Patients with a Documented Penicillin Allergy

SR | Interventions for the long‐term prevention of hereditary angioedema attacks.

27 Nov, 2022 | 22:12h | UTC

Interventions for the long‐term prevention of hereditary angioedema attacks – Cochrane Library

Summary: Drug treatments for the prevention of attacks of hereditary angioedema – Cochrane Library

Commentary on Twitter

New #CochraneEvidence – Interventions for the long‐term prevention of #HereditaryAngioedema attacks #HAE @CochraneUK @CochraneLibrary @US_HAEA @UCSDHealth @HAEDAY @VSGBI @ChariteBerlin https://t.co/jYYjmG1eGH pic.twitter.com/2z522Bw5iZ

— CochraneVasc (@CochraneVasc) November 7, 2022

Skin cancer in solid organ transplant recipients: a review for the non-dermatologist.

27 Nov, 2022 | 22:02h | UTC

Skin Cancer in Solid Organ Transplant Recipients: A Review for the Nondermatologist – Mayo Clinic Proceedings

Study shows there is substantial monkeypox transmission before symptoms appear.

25 Nov, 2022 | 12:43h | UTC

Transmission dynamics of monkeypox in the United Kingdom: contact tracing study – The BMJ

Editorial: The dynamics of monkeypox transmission – The BMJ

News Release: Evidence for “substantial” monkeypox transmission before symptoms – BMJ Newsroom

Commentaries:

Expert reaction to study looking at monkeypox transmission before symptoms appear – Science Media Centre

Study finds evidence of ‘considerable’ presymptomatic spread of monkeypox – The Guardian

RCT | Treatment of early Lyme Disease with doxycycline for 7 days is noninferior to treatment for 14 days.

23 Nov, 2022 | 14:06h | UTC

Treatment of erythema migrans with doxycycline for 7 days versus 14 days in Slovenia: a randomised open-label non-inferiority trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)

Commentary: Shorter Duration of Antibiotics Noninferior for Lyme Disease – JAMA (free for a limited period)

Commentary on Twitter

New research: Treatment of erythema migrans with doxycycline for 7 days versus 14 days in Slovenia: a randomised open-label non-inferiority trialhttps://t.co/8lktc4gxzG pic.twitter.com/mP2e0Kn7C5

— The Lancet Infectious Diseases (@TheLancetInfDis) October 7, 2022