Dermatology
Position Paper | Perioperative antibiotic prophylaxis in skin surgery
3 Aug, 2023 | 13:39h | UTCPerioperative antibiotic prophylaxis in skin surgery – Position paper of the Antibiotic Stewardship working group of the German Society for Dermatologic Surgery (DGDC) – Journal of the German Society of Dermatology
Part 1: Procedure- and patient-related risk factors
Part 2: Special indications and situations
RCT | Risankizumab outperforms apremilast in moderate plaque psoriasis treatment
3 Aug, 2023 | 13:21h | UTCCommentary: Risankizumab Shown to be Superior to Apremilast in Treating Adults with Moderate Psoriasis – HCP Live
European consensus-based interdisciplinary guideline for invasive cutaneous squamous cell carcinoma
1 Aug, 2023 | 14:24h | UTCPart 1: Diagnostics and prevention – European Journal of Cancer
Part 2: Treatment – European Journal of Cancer
M-A | Updated evidence supports incisional negative pressure wound therapy for surgical site infection prevention
1 Aug, 2023 | 14:15h | UTC
M-A | Oral isotretinoin and triple topical therapies found most effective in acne vulgaris treatment
26 Jul, 2023 | 13:13h | UTC
M-A | Comparison of systemic treatments for chronic plaque psoriasis – Anti-IL17 stands out
25 Jul, 2023 | 13:27h | UTC
Consensus Paper | Pre and post hair transplantation care
24 Jul, 2023 | 12:46h | UTC
RCT | Direct oral challenge noninferior to skin testing followed by direct oral challenge in low-risk penicillin allergy patients
18 Jul, 2023 | 13:54h | UTCEfficacy of a Clinical Decision Rule to Enable Direct Oral Challenge in Patients With Low-Risk Penicillin Allergy: The PALACE Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
See also: Visual Abstract
News Release: World-first clinical trial to help millions with penicillin allergies – Vanderbilt University Medical Center
Commentary: Trial supports use of direct oral challenge for penicillin allergy – CIDRAP
Guidelines | Management of atopic dermatitis in adults with topical therapies
14 Jul, 2023 | 12:48h | UTC
Phase 2b RCT | Therapeutic ammonia oxidising bacteria B244 shows promising efficacy in atopic dermatitis
11 Jul, 2023 | 13:40h | UTC
Consensus Paper | Methotrexate for inflammatory skin disease in pediatric patients
7 Jul, 2023 | 16:16h | UTC
EULAR points to consider for the definition of clinical and imaging features suspicious for progression from psoriasis to psoriatic arthritis
27 Jun, 2023 | 13:37h | UTC
Commentary on Twitter
Have you checked the latest recommendations? @eular_org points to consider for the definition of clinical and imaging features suspicious for progression from PsO to PsA
▶️ 3 stages relevant to PsA prevention
▶️ 5 OP and 10 points to consider? https://t.co/Kr9akTjNC6 pic.twitter.com/cHsg0ZTlb6
— ARD & RMD Open (@ARD_BMJ) June 21, 2023
Review | Deadly drug rashes: early recognition and multidisciplinary care
21 Jun, 2023 | 13:28h | UTC
Podcast | Hypopigmented and depigmented skin lesions in pediatrics
6 Jun, 2023 | 14:24h | UTC#84: Hypopigmented & Depigmented Skin Lesions: An En-LIGHT-ening Review – The Cribsiders
Guideline | Onychomycosis
1 Jun, 2023 | 12:01h | UTCGuideline onychomycosis – Journal of the German Society of Dermatology
Consensus Paper | Safe skin, safe patients: the value of patient hygiene
31 May, 2023 | 14:06h | UTCSafe Skin, Safe Patients: The Value of Patient Hygiene – Clinical Consensus Statement – American Journal of Nursing (free for a limited period)
SR | Efficacy of negative pressure wound therapy in treating pressure ulcers remains uncertain
31 May, 2023 | 13:53h | UTCNegative pressure wound therapy for treating pressure ulcers – Cochrane Library
Summary: Negative pressure wound therapy for treating pressure ulcers – Cochrane Library
RCT | Microdosed incisional clindamycin reduces infection rate in skin cancer surgery
30 May, 2023 | 12:03h | UTCEffect of Microdoses of Incisional Antibiotics on the Rate of Surgical Site Infections in Skin Cancer Surgery: A Randomized Clinical Trial – JAMA Surgery (link to abstract – $ for full-text)
See also: Visual Abstract
Commentary: Microdosed Incisional Clindamycin Cuts SSI After Skin Cancer Surgery – HealthDay
Acute generalized exanthematous pustulosis: clinical features, differential diagnosis, and management
29 May, 2023 | 10:54h | UTC
MASCC Guidelines for the prevention and management of acute radiation dermatitis | Part 1 – Systematic review
29 May, 2023 | 10:53h | UTCRelated:
RCT | Bacterial decolonization for prevention of radiation dermatitis
RCT | Mepitel film for the prevention of acute radiation dermatitis in breast cancer.
Review | Skin assessments and interventions for maintaining skin integrity in nursing practice
25 May, 2023 | 11:25h | UTC
Guidelines on the diagnosis and treatment of foot infection in persons with diabetes
24 May, 2023 | 13:30h | UTC
RCT | Spironolactone enhances acne outcomes and offers a viable alternative to oral antibiotics
24 May, 2023 | 13:27h | UTCSummary: The SAFA (Spironolactone for Adult Female Acne) trial was a multicenter, phase 3, double-blind, randomized controlled trial in England and Wales and evaluated the efficacy of spironolactone for treating adult women with acne vulgaris. A total of 410 women, aged ≥18 years and suffering from facial acne for a minimum of six months, were randomly assigned to receive either 50 mg/day of spironolactone or a placebo, increasing to 100 mg/day until week 24.
The primary outcome was measured by the Acne-Specific Quality of Life (Acne-QoL) symptom subscale score at week 12 and 24. The trial demonstrated that spironolactone improved Acne-QoL scores more effectively than the placebo, particularly at week 24. Additionally, more participants in the spironolactone group reported acne improvement, and treatment success was significantly higher in this group at week 12. Mild side effects, notably headaches, were more common in the spironolactone group.
The findings from the SAFA trial highlight spironolactone’s effectiveness, safety, and tolerability in treating adult women with acne vulgaris, suggesting it is a viable alternative to long-term antibiotic treatments. Future research is proposed on higher initial dosages of spironolactone, and its effects on different subgroups like patients with different ages, body mass index, and ethnicity.
Editorial: What do we know about prescribing spironolactone for acne? – The BMJ
News Release: Non-antibiotic treatment for women with persistent acne shown to be effective – University of Southhampton
Cohort Study | 5-mm margins may be adequate for T1a melanoma excision near critical structures
16 May, 2023 | 14:40h | UTCAssociation of Excision Margin Size With Local Recurrence and Survival in Patients With T1a Melanoma at Critical Structures – JAMA Dermatology (link to abstract – $ for full-text)
Commentary: Melanoma Excisions with 5 Millimeter Margins Linked to Less Risk of Local Recurrence – HCP Live
Commentary on Twitter
Study on thin melanomas (T1a) near critical anatomic sites such as the head and face showed that 5-mm surgical margins may be safe for patients and decrease reconstructive surgery and potential adverse, including scarring and mental issues. https://t.co/Mw7Ub4xMVX
— JAMA Dermatology (@JAMADerm) April 12, 2023
The impact of hyperhidrosis on quality of life: a review of the literature
16 May, 2023 | 14:33h | UTC