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Global & Humanitarian Medicine

Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis.

20 Jan, 2022 | 09:17h | UTC

Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis – The Lancet

News Release: An estimated 1.2 million people died in 2019 from antibiotic-resistant bacterial infections, more deaths than HIV/AIDS or malaria – The Lancet

Editorial: Antimicrobial resistance: time to repurpose the Global Fund – The Lancet

Commentary: Antimicrobial resistance now a leading cause of death worldwide, study finds – The Guardian

 

Commentary on Twitter

 

1.8 million excess deaths attributable to urban air pollution in 2019, modelling study suggests.

20 Jan, 2022 | 09:13h | UTC

News Release: The Lancet Planetary Health: 1.8 million excess deaths attributable to urban air pollution in 2019, modelling study suggests

Original Study: Global urban temporal trends in fine particulate matter (PM2·5) and attributable health burdens: estimates from global datasets – The Lancet Planetary Health

Related Studies:

Internalising health-economic impacts of air pollution into climate policy: a global modelling study – The Lancet Planetary Health

Long-term trends in urban NO2 concentrations and associated paediatric asthma incidence: estimates from global datasets – The Lancet Planetary Health

 

Commentary on Twitter (thread – click for more)

 

Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.

13 Jan, 2022 | 08:42h | UTC

Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 – The Lancet Psychiatry

Invited Commentary: The true global disease burden of mental illness: still elusive – The Lancet Psychiatry (free registration required)

 

A cluster randomized trial in a yaws-endemic area of Papua New Guinea showed a reduction in the community prevalence of yaws with three rounds of mass administration of azithromycin at 6-month intervals compared with one round of mass administration of azithromycin followed by two rounds of targeted treatment.

12 Jan, 2022 | 08:44h | UTC

Trial of Three Rounds of Mass Azithromycin Administration for Yaws Eradication – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 

WHO: 10 key global health moments from 2021.

8 Jan, 2022 | 23:20h | UTC

10 key global health moments from 2021 – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

RCT: Low-cost, easy to take antiretroviral treatment based on Dolutegravir as first- or second-Line therapy found to be non-inferior to standard care for treating HIV-1 infection in children.

8 Jan, 2022 | 23:07h | UTC

Dolutegravir as First- or Second-Line Treatment for HIV-1 Infection in Children – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Easy-to-take medicine better at suppressing HIV in children – University College London

 

Commentaries on Twitter

 

WHO Reports | More than half a billion people pushed or pushed further into extreme poverty due to health care costs.

14 Dec, 2021 | 08:55h | UTC

News release: More than half a billion people pushed or pushed further into extreme poverty due to health care costs – World Health Organization

Report 1: Tracking Universal Health Coverage: 2021 Global monitoring report – World Health Organization

Report 2: Global monitoring report on financial protection in health 2021 – World Health Organization

 

WHO Report: More malaria cases and deaths in 2020 linked to COVID-19 disruptions.

7 Dec, 2021 | 08:55h | UTC

News Release: More malaria cases and deaths in 2020 linked to COVID-19 disruptions – World Health Organization

Report: World Malaria Report 2021 – World Health Organization

Commentaries:

More people died of malaria in 2020 than in 2019. Here’s why – NPR

Malaria kills 180,000 more people annually than previously thought, says WHO – The Guardian

 

Commentary on Twitter (thread – click for more)

 

The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019.

5 Dec, 2021 | 23:09h | UTC

The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019 – The Lancet Oncology

Invited Commentary: Burden of cancer in adolescents and young adults – The Lancet Oncology

 

Global estimates of viral suppression in 31 countries shows too many people with HIV fail to achieve durable viral suppression.

1 Dec, 2021 | 08:41h | UTC

News Release: Too many people with HIV fail to achieve durable viral suppression – NIH News Releases

Original Study: Global estimates of viral suppression in children and adolescents and adults on antiretroviral therapy adjusted for missing viral load measurements: a multiregional, retrospective cohort study in 31 countries – The Lancet HIV (link to abstract – $ for full-text)

 

Review: Prevention of emerging infections in children.

23 Nov, 2021 | 08:17h | UTC

Prevention of Emerging Infections in Children – Pediatric Clinics of North America

 

[Not published yet] Single-dose HPV vaccine highly effective, researchers say – “Results of randomized controlled trial in Kenya bring new energy to eliminate cervical cancer worldwide”.

21 Nov, 2021 | 22:56h | UTC

Single-dose HPV vaccine highly effective, researchers say – University of Washington School of Medicine

Related:

A national HPV vaccination program in England was associated with an estimated reduction in cervical cancer rates of 87% for those offered the vaccine at age 12–13 years.

Three-year follow-up of 2-dose versus 3-dose HPV vaccine

Nationwide cohort study in Sweden shows HPV vaccination linked to reduced risk of invasive cervical cancer

CDC: 92% of Human Papillomavirus–Attributable Cancers can be Targeted by HPV Vaccination

Meta-Analysis: Population-level Impact of HPV Vaccination Programs

 

Global tuberculosis progress reversed by COVID-19 pandemic.

19 Nov, 2021 | 10:51h | UTC

Global tuberculosis progress reversed by COVID-19 pandemic – The Lancet Respiratory Diseases

Related:

WHO Report: Tuberculosis deaths rise for the first time in more than a decade due to the COVID-19 pandemic.

How COVID is derailing the fight against HIV, TB and malaria.

How COVID hurt the fight against other dangerous diseases

World TB Day | Report: COVID-19 Eliminates Twelve Years of Progress Against Tuberculosis

WHO: Benefits of continuing to provide life-saving HIV services outweigh the risk of COVID-19 transmission by 100 to 1

Tuberculosis and Covid-19: Fighting a deadly syndemic

Potential impact of the COVID-19 pandemic on HIV, tuberculosis, and malaria in low-income and middle-income countries: a modelling study

 

Commentary on Twitter

 

New WHO report maps barriers to insulin availability and suggests actions to promote universal access – “100 years after its discovery, insulin still out of reach for many living with diabetes”.

16 Nov, 2021 | 08:34h | UTC

News Release: New WHO report maps barriers to insulin availability and suggests actions to promote universal access – World Health Organization

Report: Keeping the 100-year-old promise: making insulin access universal – World Health Organization

Commentary: Half the People Living with Diabetes Can’t Afford Insulin, WHO Report Shows – Health Policy Watch

Related:

Editorial | Insulin for all: a hope yet to be realized.

One hundred years of insulin therapy.

The state of diabetes treatment coverage in 55 low-income and middle-income countries – fewer than one in ten people with diabetes in LMICs receive comprehensive care such as low-cost medicines to reduce blood sugar, blood pressure and cholesterol levels, in addition to counseling on diet, exercise and weight.

 

Commentary on Twitter (thread – click for more)

 

#AHA21 – RCT: Among children and adolescents who had screening echocardiograms and were identified as having latent rheumatic heart disease, secondary antibiotic prophylaxis with penicillin G benzathine for 2 years was associated with reduced echocardiographic progression (0.8 vs. 8.2% in the control group).

14 Nov, 2021 | 20:03h | UTC

Secondary Antibiotic Prophylaxis for Latent Rheumatic Heart Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

Penicillin significantly reduces rheumatic heart disease progression in children – Murdoch Children’s Research Institute

Penicillin slows devastating impacts of rheumatic heart disease in children from Uganda – Children’s National Hospital

Secondary Antibiotic Prophylaxis for Latent Rheumatic Heart Disease – American College of Cardiology

 

Commentaries on Twitter

 

Extreme heat is broiling people in developing cities: New analysis finds the explosive growth of cities is helping drive dangerous conditions.

24 Oct, 2021 | 23:34h | UTC

Extreme heat is broiling people in developing cities – Science

Original Study: Global urban population exposure to extreme heat – Proceedings of the National Academy of Sciences

 

Commentary on Twitter

 

Health care–acquired infections in low- and middle-income countries and the role of infection prevention and control.

22 Oct, 2021 | 10:09h | UTC

Health Care–Acquired Infections in Low- and Middle-Income Countries and the Role of Infection Prevention and Control – Infectious Disease Clinics of North America

 

WHO Report: Tuberculosis deaths rise for the first time in more than a decade due to the COVID-19 pandemic.

15 Oct, 2021 | 02:30h | UTC

Tuberculosis deaths rise for the first time in more than a decade due to the COVID-19 pandemic – World Health Organization

Report: Global tuberculosis report 2021

Commentary: Tuberculosis deaths rise for 1st time in years, due to COVID – Associated Press

 

Commentary on Twitter (thread – click for more)

 

Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018.

13 Oct, 2021 | 01:21h | UTC

Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018 – Nature Medicine

Invited commentary: Anemia in women — an intractable problem that requires innovative solutions – Nature Medicine

 

WHO report highlights global shortfall in investment in mental health.

10 Oct, 2021 | 21:39h | UTC

WHO report highlights global shortfall in investment in mental health – World Health Organization

Report: Mental Health ATLAS 2020 – World Health Organization

See also: World Mental Health Day 2021: Mental health care for all: let’s make it a reality – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

Systematic Review: Administration of antimalarial drugs to whole populations for reducing malaria.

7 Oct, 2021 | 10:36h | UTC

Administration of antimalarial drugs to whole populations for reducing malaria – Cochrane Library

Original study: Mass drug administration for malaria – Cochrane Library

 

Commentary on Twitter

 

WHO approves first ever malaria vaccine for children at risk.

7 Oct, 2021 | 10:40h | UTC

WHO recommends groundbreaking malaria vaccine for children at risk – World Health Organization

Commentaries:

WHO Approves First Ever Malaria Vaccine – Health Policy Watch

A historic day for malaria – reaction to WHO decision on the RTS,S vaccine – London School of Hygiene & Tropical Medicine

In major decision, WHO recommends broad rollout of world’s first malaria vaccine – STAT

Why the WHO approval of the first malaria vaccine is a big deal – Vox

WHO greenlights the world’s first malaria vaccine — but it’s not a perfect shot – NPR

The World Health Organization Just Endorsed The World’s First Malaria Vaccine – TIME

WHO Backs Widespread Use Of First Malaria Vaccine – Forbes

World’s 1st malaria vaccine recommended by WHO – LiveScience

 

Commentaries on Twitter

(thread – click for more)

 

The Lancet Commission: transforming access to diagnostics.

7 Oct, 2021 | 10:33h | UTC

News release: The Lancet: Half of the global population lack access to basic diagnostics for many common diseases

Video: Transforming access to diagnostics | The Lancet Commission on diagnostics

Homepage: The Lancet Commission on diagnostics: transforming access to diagnostics

The Lancet Commission on diagnostics: transforming access to diagnostics (free registration required)

Transforming access to diagnostics: how to turn good intentions into action? (free registration required)

Can COVID-19 help accelerate and transform the diagnostics agenda?

Availability of essential diagnostics in ten low-income and middle-income countries: results from national health facility surveys

Commentary: A Grim Diagnosis – Half The World’s Population Has Limited Access To Diagnostics – Forbes

Related:

WHO Updates Global Guidance on Medicines and Diagnostic Tests

The WHO Essential Diagnostic List: A Tool for the Future

Perspective: Health Care is an Essential Human Right – And So Is a Proper Diagnosis

Report: First-ever WHO List of Essential Diagnostic Tests

 

Commentary on Twitter

 

Supplement: Triumphs of Vaccination.

6 Oct, 2021 | 08:55h | UTC

Homepage: Triumphs of Vaccination – The Journal of Infectious Diseases

Triumphs of Immunization

Pertussis (Whooping Cough)

Hib Vaccines: Their Impact on Haemophilus influenzae Type b Disease

The Rotavirus Vaccine Story: From Discovery to the Eventual Control of Rotavirus Disease

Hepatitis B Vaccines

Triumph of Pneumococcal Conjugate Vaccines: Overcoming a Common Foe

Rubella Eradication: Not Yet Accomplished, but Entirely Feasible

Human Papillomavirus Vaccines

Smallpox

Live Attenuated Varicella Vaccine: Prevention of Varicella and of Zoster

Immunization Against Poliomyelitis and the Challenges to Worldwide Poliomyelitis Eradication

Influenza Vaccines: Successes and Continuing Challenges

Measles in the 21st Century: Progress Toward Achieving and Sustaining Elimination

Herpes Zoster Vaccines

Overview of the United States’ Immunization Program

The World of Immunization: Achievements, Challenges, and Strategic Vision for the Next Decade

 

WHO prioritizes access to diabetes and cancer treatments in new Essential Medicines Lists.

3 Oct, 2021 | 22:46h | UTC

News Release: WHO prioritizes access to diabetes and cancer treatments in new Essential Medicines Lists – World Health Organization

Report: WHO model list of essential medicines – 22nd list, 2021 – World Health Organization

Commentary: For the first time, WHO committee recommends action on high-priced essential medicines – STAT

 

Commentary on Twitter (thread – click for more)

 

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