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Oncology

Systematic review: Therapies for clinically localized prostate cancer

20 Sep, 2020 | 21:15h | UTC

Therapies for Clinically Localized Prostate Cancer – Agency for Healthcare Research and Quality

Final report: Therapies for Clinically Localized Prostate Cancer AND Evidence Summary

 


[Abstract Only] Survival with Olaparib in metastatic castration-resistant prostate cancer

20 Sep, 2020 | 21:13h | UTC

Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer – New England Journal of Medicine

 

Commentary on Twitter

 


[Abstract Only] Avelumab maintenance therapy for advanced or metastatic urothelial carcinoma

20 Sep, 2020 | 21:11h | UTC

Avelumab Maintenance Therapy for Advanced or Metastatic Urothelial Carcinoma – New England Journal of Medicine

 

Commentary on Twitter

 

 


[Abstract Only] Randomized trial: Preoperative radiotherapy plus surgery vs. surgery alone for patients with primary retroperitoneal sarcoma

16 Sep, 2020 | 08:46h | UTC

Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label, randomised, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

 


Consensus Statement: Cardio‐oncology care in the era of the COVID‐19 pandemic

14 Sep, 2020 | 00:54h | UTC

Cardio‐oncology care in the era of the coronavirus disease 2019 (COVID‐19) pandemic: An International Cardio‐Oncology Society (ICOS) statement – CA: A Cancer Journal for Clinicians

 

Commentary on Twitter

 


[Abstract Only] Randomized trial: Nonmetastatic, castration-resistant prostate cancer and survival with darolutamide

10 Sep, 2020 | 09:33h | UTC

Nonmetastatic, Castration-Resistant Prostate Cancer and Survival with Darolutamide – New England Journal of Medicine

 


Cohort study: COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumor subtype and patient demographics

6 Sep, 2020 | 21:42h | UTC

COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumour subtype and patient demographics: a prospective cohort study – The Lancet Oncology

Commentaries: New study describes which cancer patients are more vulnerable to COVID-19 – University of Birmingham AND COVID-19 Prevalence and Mortality in Patients With Cancer in the UK – The ASCO Post

 


ESMO Expert Consensus: Managing cancer patients during the COVID-19 pandemic

6 Sep, 2020 | 21:40h | UTC

Managing cancer patients during the COVID-19 pandemic: An ESMO Interdisciplinary Expert Consensus – Annals of Oncology

 


Malignant pleural effusions: New evidence on management

4 Sep, 2020 | 02:03h | UTC

Malignant pleural effusions (MPE): new evidence on management – Evidently Cochrane

Original Review: Interventions for the management of malignant pleural effusions: a network meta‐analysis – Cochrane Library

 


[Abstract Only] CAR T-cell therapy for patients with relapsed or refractory large B-cell lymphomas

3 Sep, 2020 | 10:56h | UTC

Lisocabtagene maraleucel for patients with relapsed or refractory large B-cell lymphomas (TRANSCEND NHL 001): a multicentre seamless design study – The Lancet (link to abstract – $ for full-text)

 


[Abstract Only] Randomized trial: Second-look surgery plus hyperthermic intraperitoneal chemotherapy vs. surveillance in patients at high risk of developing colorectal peritoneal metastases

2 Sep, 2020 | 09:31h | UTC

Second-look surgery plus hyperthermic intraperitoneal chemotherapy versus surveillance in patients at high risk of developing colorectal peritoneal metastases (PROPHYLOCHIP–PRODIGE 15): a randomised, phase 3 study – The Lancet Oncology

Commentary: Second-Look Surgery Plus HIPEC vs Surveillance for Patients at High Risk for Colorectal Peritoneal Metastases – The ASCO Post

 


Randomized trial: Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy for early breast cancer

21 Aug, 2020 | 02:27h | UTC

Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial – The BMJ

Commentaries: Targeted intraoperative radiotherapy for early breast cancer—new evidence challenges traditional treatment – The BMJ Opinion AND Long-term TARGIT-A data support single-dose intraoperative breast cancer radiotherapy – medwire News

 


[Abstract Only] Randomized trial: Laparoscopic vs. open total gastrectomy for clinical stage I gastric cancer

21 Aug, 2020 | 02:18h | UTC

Morbidity and Mortality of Laparoscopic vs Open Total Gastrectomy for Clinical Stage I Gastric Cancer: The CLASS02 Multicenter Randomized Clinical Trial – JAMA Oncology

 


[Abstract Only] Randomized trial: Hypofractionated vs. conventional fractionated radiotherapy after breast-conserving surgery

18 Aug, 2020 | 07:15h | UTC

Hypofractionated Versus Conventional Fractionated Radiotherapy After Breast-Conserving Surgery in the Modern Treatment Era: A Multicenter, Randomized Controlled Trial From China – Journal of Clinical Oncology

 


Prioritizing primary care patients with unexpected weight loss for cancer investigation: Diagnostic accuracy study

16 Aug, 2020 | 22:08h | UTC

Prioritising primary care patients with unexpected weight loss for cancer investigation: diagnostic accuracy study – The BMJ

Commentaries: When does unexpected weight loss warrant cancer investigation? – The BMJ Opinion

 

Commentary on Twitter

 


Randomized trial: Effect of mammographic screening from age 40 years on breast cancer mortality

14 Aug, 2020 | 01:09h | UTC

Effect of mammographic screening from age 40 years on breast cancer mortality (UK Age trial): final results of a randomised, controlled trial – The Lancet Oncology

Commentaries: Study revives debate over breast cancer screening age – The Guardian AND Expert reaction to study looking at breast screening women in their 40s and cancer deaths – Science Media Centre AND Final results of the UK Age trial on breast cancer screening age – The Lancet Oncology

 


Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT

13 Aug, 2020 | 00:02h | UTC

Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT – Health Technology Assessment

 


[Abstract Only] Randomized trial: Effect of aspirin on cancer incidence and mortality in older adults

12 Aug, 2020 | 23:59h | UTC

Effect of aspirin on cancer incidence and mortality in older adults – JNCI: Journal of the National Cancer Institute

Commentary: Aspirin may accelerate progression of advanced cancers in older adults – Massachusetts General Hospital

 


MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy

12 Aug, 2020 | 02:20h | UTC

MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy – Cancer

Commentary: New guidelines for managing mucositis now available – University of Rochester Medical Center

 


Guideline: Systemic anticancer therapy-induced peripheral and central neurotoxicity

7 Aug, 2020 | 03:07h | UTC

Systemic anticancer therapy-induced peripheral and central neurotoxicity: ESMO–EONS–EANO Clinical Practice Guidelines for diagnosis, prevention, treatment and follow-up – Annals of Oncology

 


Choosing Wisely Africa: Ten low-value or harmful practices that should be avoided in cancer care

7 Aug, 2020 | 03:06h | UTC

Choosing Wisely Africa: Ten Low-Value or Harmful Practices That Should Be Avoided in Cancer Care – JCO Global Oncology

 


Are observational, real-world studies suitable to make cancer treatment recommendations?

3 Aug, 2020 | 00:17h | UTC

Are Observational, Real-World Studies Suitable to Make Cancer Treatment Recommendations? – JAMA Network Open

Original Study: Evaluation of the Use of Cancer Registry Data for Comparative Effectiveness Research – JAMA Network Open

 


Cervical cancer screening for individuals at average risk: 2020 guideline update from the American Cancer Society

31 Jul, 2020 | 08:34h | UTC

Cervical cancer screening for individuals at average risk: 2020 guideline update from the American Cancer Society – CA: A Cancer Journal for Clinicians

Commentaries: Updated cervical cancer screening guideline calls for less and more simplified screening – News Medical AND Cervical Cancer Screening Should Begin Later, Cancer Group Says – NEJM Journal Watch AND American Cancer Society now recommends cervical cancer screening start at 25, not 21 – CNN

 


Non-invasive early detection of cancer four years before conventional diagnosis using a blood test

27 Jul, 2020 | 09:37h | UTC

Non-invasive early detection of cancer four years before conventional diagnosis using a blood test – Nature Communications

 


[Abstract Only] Randomized trial: Carfilzomib, dexamethasone, and daratumumab vs. carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma

22 Jul, 2020 | 02:11h | UTC

Carfilzomib, dexamethasone, and daratumumab versus carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma (CANDOR): results from a randomised, multicentre, open-label, phase 3 study – The Lancet

 


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