Oncology
Systematic review: Therapies for clinically localized prostate cancer
20 Sep, 2020 | 21:15h | UTCTherapies for Clinically Localized Prostate Cancer – Agency for Healthcare Research and Quality
Final report: Therapies for Clinically Localized Prostate Cancer AND Evidence Summary
[Abstract Only] Survival with Olaparib in metastatic castration-resistant prostate cancer
20 Sep, 2020 | 21:13h | UTC
Commentary on Twitter
The PROfound trial showed that olaparib prolonged imaging-based progression-free survival among patients whose tumors contained defects in the BRCA1, BRCA2, or ATM. With longer follow-up, the trial now shows that olaparib prolonged overall survival in these patients. #ESMO20
— NEJM (@NEJM) September 20, 2020
[Abstract Only] Avelumab maintenance therapy for advanced or metastatic urothelial carcinoma
20 Sep, 2020 | 21:11h | UTC
Commentary on Twitter
Maintenance avelumab plus best supportive care significantly prolonged overall survival, as compared with best supportive care alone, among patients with urothelial cancer who had disease that had not progressed with first-line chemotherapy. #ESMO20
— NEJM (@NEJM) September 18, 2020
[Abstract Only] Randomized trial: Preoperative radiotherapy plus surgery vs. surgery alone for patients with primary retroperitoneal sarcoma
16 Sep, 2020 | 08:46h | UTCPreoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label, randomised, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)
Consensus Statement: Cardio‐oncology care in the era of the COVID‐19 pandemic
14 Sep, 2020 | 00:54h | UTC
Commentary on Twitter
CA: A Cancer Journal Article on COVID and Cardio-Oncology Care from International Cardio-Oncology team of global experts! An outstanding achievement by our community- read it here: https://t.co/4GqnZfbWXN pic.twitter.com/9m9n744jSo
— International Cardio-Oncology Society (@ICOSociety) September 11, 2020
[Abstract Only] Randomized trial: Nonmetastatic, castration-resistant prostate cancer and survival with darolutamide
10 Sep, 2020 | 09:33h | UTC
Cohort study: COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumor subtype and patient demographics
6 Sep, 2020 | 21:42h | UTCCommentaries: New study describes which cancer patients are more vulnerable to COVID-19 – University of Birmingham AND COVID-19 Prevalence and Mortality in Patients With Cancer in the UK – The ASCO Post
ESMO Expert Consensus: Managing cancer patients during the COVID-19 pandemic
6 Sep, 2020 | 21:40h | UTC
Malignant pleural effusions: New evidence on management
4 Sep, 2020 | 02:03h | UTCMalignant pleural effusions (MPE): new evidence on management – Evidently Cochrane
Original Review: Interventions for the management of malignant pleural effusions: a network meta‐analysis – Cochrane Library
[Abstract Only] CAR T-cell therapy for patients with relapsed or refractory large B-cell lymphomas
3 Sep, 2020 | 10:56h | UTCLisocabtagene maraleucel for patients with relapsed or refractory large B-cell lymphomas (TRANSCEND NHL 001): a multicentre seamless design study – The Lancet (link to abstract – $ for full-text)
[Abstract Only] Randomized trial: Second-look surgery plus hyperthermic intraperitoneal chemotherapy vs. surveillance in patients at high risk of developing colorectal peritoneal metastases
2 Sep, 2020 | 09:31h | UTC
Randomized trial: Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy for early breast cancer
21 Aug, 2020 | 02:27h | UTCCommentaries: Targeted intraoperative radiotherapy for early breast cancer—new evidence challenges traditional treatment – The BMJ Opinion AND Long-term TARGIT-A data support single-dose intraoperative breast cancer radiotherapy – medwire News
[Abstract Only] Randomized trial: Laparoscopic vs. open total gastrectomy for clinical stage I gastric cancer
21 Aug, 2020 | 02:18h | UTC
[Abstract Only] Randomized trial: Hypofractionated vs. conventional fractionated radiotherapy after breast-conserving surgery
18 Aug, 2020 | 07:15h | UTC
Prioritizing primary care patients with unexpected weight loss for cancer investigation: Diagnostic accuracy study
16 Aug, 2020 | 22:08h | UTCCommentaries: When does unexpected weight loss warrant cancer investigation? – The BMJ Opinion
Commentary on Twitter
The risk of cancer in adults with unexpected weight loss presenting to primary care is 2% or less and does not merit investigation under current UK guidelines, suggests new research @BrianDNicholson https://t.co/j1Wf74HSqV
— The BMJ (@bmj_latest) August 15, 2020
Randomized trial: Effect of mammographic screening from age 40 years on breast cancer mortality
14 Aug, 2020 | 01:09h | UTCCommentaries: Study revives debate over breast cancer screening age – The Guardian AND Expert reaction to study looking at breast screening women in their 40s and cancer deaths – Science Media Centre AND Final results of the UK Age trial on breast cancer screening age – The Lancet Oncology
Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT
13 Aug, 2020 | 00:02h | UTC
[Abstract Only] Randomized trial: Effect of aspirin on cancer incidence and mortality in older adults
12 Aug, 2020 | 23:59h | UTCCommentary: Aspirin may accelerate progression of advanced cancers in older adults – Massachusetts General Hospital
MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy
12 Aug, 2020 | 02:20h | UTCCommentary: New guidelines for managing mucositis now available – University of Rochester Medical Center
Guideline: Systemic anticancer therapy-induced peripheral and central neurotoxicity
7 Aug, 2020 | 03:07h | UTC
Choosing Wisely Africa: Ten low-value or harmful practices that should be avoided in cancer care
7 Aug, 2020 | 03:06h | UTC
Are observational, real-world studies suitable to make cancer treatment recommendations?
3 Aug, 2020 | 00:17h | UTCOriginal Study: Evaluation of the Use of Cancer Registry Data for Comparative Effectiveness Research – JAMA Network Open
Cervical cancer screening for individuals at average risk: 2020 guideline update from the American Cancer Society
31 Jul, 2020 | 08:34h | UTCCommentaries: Updated cervical cancer screening guideline calls for less and more simplified screening – News Medical AND Cervical Cancer Screening Should Begin Later, Cancer Group Says – NEJM Journal Watch AND American Cancer Society now recommends cervical cancer screening start at 25, not 21 – CNN
Non-invasive early detection of cancer four years before conventional diagnosis using a blood test
27 Jul, 2020 | 09:37h | UTC
[Abstract Only] Randomized trial: Carfilzomib, dexamethasone, and daratumumab vs. carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma
22 Jul, 2020 | 02:11h | UTC