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Oncology

Opinion: Covid-19 Pandemic—An Opportunity to Reduce and Eliminate Low-Value Practices in Oncology?

3 Jul, 2020 | 08:26h | UTC

Covid-19 Pandemic—An Opportunity to Reduce and Eliminate Low-Value Practices in Oncology? – JAMA Oncology (free for a limited period)

 


Randomized Trial: Ursodeoxycholic Acid for the Prevention of Gallstone Formation After Gastrectomy in Patients With Gastric Cancer

29 Jun, 2020 | 09:00h | UTC

Efficacy and Safety of Ursodeoxycholic Acid for the Prevention of Gallstone Formation After Gastrectomy in Patients With Gastric Cancer: The PEGASUS-D Randomized Clinical Trial – JAMA Surgery

Commentary: Daily UDCA Reduced Gallstone Formation in Gastric Cancer Patients Following Gastrectomy – Physician’s Weekly

 


Treatment of Locally Advanced Esophageal Carcinoma: ASCO Guideline

24 Jun, 2020 | 03:16h | UTC

Treatment of Locally Advanced Esophageal Carcinoma: ASCO Guideline – Journal of Clinical Oncology

 


What Oncologists Should Know About Treating Sexual and Gender Minority Patients with Cancer

19 Jun, 2020 | 09:30h | UTC

What Oncologists Should Know About Treating Sexual and Gender Minority Patients with Cancer – JCO Oncology Practice

 


Randomized Trial: Atezolizumab, Vemurafenib, and Cobimetinib for Advanced BRAFV600 Mutation-positive Melanoma

16 Jun, 2020 | 07:48h | UTC

Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAFV600 mutation-positive melanoma (IMspire150): primary analysis of the randomised, double-blind, placebo-controlled, phase 3 trial – The Lancet

 


Analysis: Shifting, Overlapping and Expanding Use of “Precision Oncology” Terminology

16 Jun, 2020 | 07:46h | UTC

Shifting, overlapping and expanding use of “precision oncology” terminology: a retrospective literature analysis – BMJ Open

 


Randomized Trial: Cancer Prevention with Aspirin in Hereditary Colorectal Cancer (Lynch syndrome)

12 Jun, 2020 | 09:04h | UTC

Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial – The Lancet

Invited Commentary: Aspirin for Lynch syndrome: a legacy of prevention – The Lancet

 


Global Trends in Thyroid Cancer Incidence and the Impact of Overdiagnosis

12 Jun, 2020 | 08:59h | UTC

Global trends in thyroid cancer incidence and the impact of overdiagnosis – The Lancet Diabetes & Endocrinology (free for a limited period)

Commentaries: New IARC study on global expansion in overdiagnosis of thyroid cancer – International Agency for Research on Cancer AND Thyroid cancer overdiagnosis reaches beyond affluent regions – MDedge

 


ASTRO Guideline: Radiation Therapy for Cervical Cancer

11 Jun, 2020 | 09:20h | UTC

Radiation Therapy for Cervical Cancer: Executive Summary of an ASTRO Clinical Practice Guideline – Practical Radiation Oncology

Commentary: ASTRO’s new guideline provides recommendations for radiation therapy to treat cervical cancer – News Medical

 


American Cancer Society Guideline for Diet and Physical Activity for Cancer Prevention

10 Jun, 2020 | 04:46h | UTC

American Cancer Society Guideline for Diet and Physical Activity for cancer prevention – CA: A Cancer Journal for Clinicians

News Release: American Cancer Society Updates Diet & Physical Activity Guideline for Cancer Prevention

 


Systematic Review: Radical Prostatectomy vs. Deferred Treatment for Localized Prostate Cancer

5 Jun, 2020 | 04:34h | UTC

Radical prostatectomy versus deferred treatment for localised prostate cancer – Cochrane Library

Summary: Radical prostatectomy versus deferred treatment for the treatment of localised prostate cancer – Cochrane Library

 


[Abstract Only] Randomized Trial: 39·0°C vs. 38·5°C Ear Temperature as Fever Limit in Children with Neutropenia Undergoing Chemotherapy for Cancer

3 Jun, 2020 | 03:34h | UTC

39·0°C versus 38·5°C ear temperature as fever limit in children with neutropenia undergoing chemotherapy for cancer: a multicentre, cluster-randomised, multiple-crossover, non-inferiority trial – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)

 


ASCO Special Report: A Guide to Cancer Care Delivery During the COVID-19 Pandemic

2 Jun, 2020 | 04:57h | UTC

ASCO Special Report: A Guide to Cancer Care Delivery During the COVID-19 Pandemic – American Society of Clinical Oncology

News Release: Special Report Provides Guidance to Oncology Practices on Resuming Cancer Care During COVID-19 Pandemic

Related: ESMO Guidelines: Cancer Patient Management During the Covid-19 Pandemic

 


Cohort Studies: Clinical Impact of COVID-19 on Patients with Cancer

1 Jun, 2020 | 04:00h | UTC

Study 1: Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study – The Lancet

Study 2: COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study – The Lancet

Commentaries: Studies highlight COVID-19 impact on cancer patients – CIDRAP AND Cancer, coronavirus are a dangerous mix, new studies find – MedicalXpress AND Cancer, coronavirus are a dangerous mix, new studies find – Associated Press AND Cancer and COVID-19: what do we really know? – The Lancet

Related: Cancer patients and research during COVID-19 pandemic: A systematic review of current evidence – Critical Reviews in Oncology/Hematology

 


[Abstract Only] #ASCO20 – Randomized Trial: Enzalutamide and Survival in Nonmetastatic, Castration-Resistant Prostate Cancer

1 Jun, 2020 | 03:33h | UTC

Enzalutamide and Survival in Nonmetastatic, Castration-Resistant Prostate Cancer – New England Journal of Medicine

 


[Abstract Only] #ASCO20 – Trastuzumab Deruxtecan in Previously Treated HER2-Positive Gastric Cancer

1 Jun, 2020 | 03:32h | UTC

Trastuzumab Deruxtecan in Previously Treated HER2-Positive Gastric Cancer – New England Journal of Medicine

 


Meta-Analysis: Direct Oral Anticoagulants vs. Low‐molecular‐weight Heparin for the Treatment of Cancer‐associated Thrombosis

29 May, 2020 | 03:03h | UTC

Direct oral anticoagulants compared to low‐molecular‐weight heparin for the treatment of cancer‐associated thrombosis: Updated systematic review and meta‐analysis of randomized controlled trials – Research and Practice in Thrombosis and Haemostasis

“In patients with cancer‐associated VTE, DOACs are more effective in preventing recurrent VTE compared to LMWH. However, risk of bleeding is increased with DOACs, especially in patients with GI cancer.”

 


Meta-Analysis: Negative Predictive Value of MRI in the Detection of Clinically Significant Prostate Cancer

28 May, 2020 | 09:35h | UTC

Negative Predictive Value of Multiparametric Magnetic Resonance Imaging in the Detection of Clinically Significant Prostate Cancer in the Prostate Imaging Reporting and Data System Era: A Systematic Review and Meta-analysis – European Urology

 


Impact of COVID-19 on Oncology Clinical Trials

26 May, 2020 | 09:40h | UTC

Impact of COVID-19 on oncology clinical trials – Nature Reviews Drug Discovery

Commentary: More Than 200 International Cancer Trials Suspended Due to COVID-19 – Medscape (free registration required)

 


Summary of International Recommendations in 23 Languages for Patients with Cancer During the COVID-19 Pandemic

15 May, 2020 | 03:29h | UTC

Summary of international recommendations in 23 languages for patients with cancer during the COVID-19 pandemic – The Lancet Oncology

Related: ESMO Guidelines: Cancer Patient Management During the Covid-19 Pandemic (guidelines on the subject)

 


[Abstract Only] Randomized Trial: Improved Overall Survival with Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma

15 May, 2020 | 03:23h | UTC

Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma – New England Journal of Medicine

See also: Visual Abstract

 


[Abstract Only] Cost–benefit Analysis of Cancer Drugs in the USA and Europe

14 May, 2020 | 02:25h | UTC

Prices and clinical benefit of cancer drugs in the USA and Europe: a cost–benefit analysis – The Lancet Oncology (link to abstract – $ for full-text)

Commentaries: High cost of cancer drugs not always justified – University of Zurich AND High Cost of Cancer Drugs Does Not Reflect Clinical Benefit – Medscape

 


NCCN Guideline: Hematopoietic Cell Transplantation

10 May, 2020 | 23:53h | UTC

Hematopoietic Cell Transplantation, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network

 


ESMO Guidelines: Cancer Patient Management During the Covid-19 Pandemic

5 May, 2020 | 04:41h | UTC

Cancer Patient Management During the Covid-19 Pandemic – European Society of Medical Oncology

Related: NCCN Guidance: How to Keep our Oncology Patients and Healthcare Workers Safe AND ASCO Recommendations for the Oncology Community During the COVID19 Pandemic AND COVID-19 rapid guideline: delivery of systemic anticancer treatments – NICE AND COVID-19 rapid guideline: delivery of radiotherapy – NICE AND Caring for patients with cancer in the COVID-19 era – Nature Medicine

 


EULAR Recommendations: Diagnosis and Management of Rheumatic Adverse Events due to Cancer Immunotherapy

5 May, 2020 | 05:18h | UTC

EULAR points to consider for the diagnosis and management of rheumatic immune-related adverse events due to cancer immunotherapy with checkpoint inhibitors – Annals of Rheumatic Diseases

Related: Clinical characteristics of rheumatic syndromes associated with checkpoint inhibitors therapy – Rheumatology AND Musculoskeletal and Rheumatic Diseases Induced by Immune Checkpoint Inhibitors: A Review of the Literature – Current Drug Safety AND Immune-related Adverse Events Associated with Cancer Immunotherapy: A Review for the Practicing Rheumatologist – The Journal of Rheumatology AND NCCN Guidelines Insights: Management of Immunotherapy-Related Toxicities (guidelines and reviews on the subject)

 


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