Oncology
Randomized trial: Colorectal cancer screening with repeated fecal immunochemical tests detects more colorectal cancer and advanced adenomas compared to screening sigmoidoscopy
25 Nov, 2020 | 09:05h | UTCColorectal cancer screening with repeated fecal immunochemical test versus sigmoidoscopy: baseline results from a randomized trial – Gastroenterology (link to abstract – $ for full-text)
Systematic review: Interventions for breathlessness in patients with advanced cancer
23 Nov, 2020 | 09:43h | UTCFull report: Interventions for breathlessness in patients with advanced cancer
Evidence Summary: Interventions for breathlessness in patients with advanced cancer
Treatment of community-acquired pneumonia in immunocompromised adults: A consensus statement regarding initial strategies
17 Nov, 2020 | 09:40h | UTCEditorial: Management of Community-Acquired Pneumonia in Immunocompromised Adults – CHEST
Guideline synopsis for follow-up colonoscopy after polypectomy. Repeat Col in 7 to 10 y after 1 to 2 tubular adenomas (TA) < 10 mm; Repeat Col in 3 to 5 y after 3 to 4 TA < 10 mm; Repeat Col in 3 y after 5 to 10 TA < 10 mm; Repeat Col in 3 years after 1 or more TA > 10 mm
9 Nov, 2020 | 01:17h | UTCRecommendations for Follow-up Colonoscopy After Polypectomy – JAMA (free for a limited period)
Author interview: New Recommendations for How Often to Repeat Colonoscopy Following Polypectomy
Original guideline: Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology
Meta-analysis: Increased mortality due to cancer treatment delay
5 Nov, 2020 | 09:03h | UTCMortality due to cancer treatment delay: systematic review and meta-analysis – The BMJ
Editorial: Prioritising research into cancer treatment delays – The BMJ
Commentary on Twitter
People whose treatment for cancer is delayed by even one month have in many cases a 6 to 13% higher risk of dying – a risk that keeps rising the longer their treatment does not begin, suggests new research @HannaRadOnc https://t.co/KAmY3vx9jy
— The BMJ (@bmj_latest) November 5, 2020
[Abstract Only] Randomized, open-label trial: Olanzapine seems effective for the prevention of vomiting in children and adolescents receiving highly emetogenic chemotherapy
5 Nov, 2020 | 08:48h | UTCOlanzapine for Prevention of Vomiting in Children and Adolescents Receiving Highly Emetogenic Chemotherapy: Investigator-Initiated, Randomized, Open-Label Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentary on Twitter
RCT of adding Olanzapine to Nausea regimen (aprepitant, ondan, dex)
231 children, cycle 1 of highly emetogenic chemo
Primary endpoint: complete response= no vomiting + no rescue med use
78% v 59% day 1
74% v 47% days 1-5
64% v 38% overall#supponc https://t.co/cZFM8bLXKg— Arjun Gupta (@guptaarjun90) September 16, 2020
Study provides new estimates of breast cancer risks associated with different hormone replacement therapy preparations
30 Oct, 2020 | 01:04h | UTCCommentaries: Study provides new estimates of breast cancer risks associated with HRT – University of Oxford AND New estimates of breast cancer risks associated with HRT – The BMJ AND HRT: Breast Ca Risk Tied to Hormone Type, Duration of Tx – Physician’s Weekly
KDIGO Controversies Conference on onco-nephrology
30 Oct, 2020 | 01:03h | UTC
Commentary on Twitter
.@goKDIGO Controversies Conference on onco-nephrology: understanding kidney impairment and solid-organ malignancies, and managing kidney cancer ca. 2020 from @Kidney_Int #Nephpearls#Onconephrology 🦀
👉🏼 https://t.co/u6ANtXdKfy pic.twitter.com/4xJ0gGohoE— Edgar V. Lerma 🇵🇭 (@edgarvlermamd) October 28, 2020
Randomized trial: Osimertinib in resected EGFR-Mutated non–small-cell lung cancer
29 Oct, 2020 | 09:04h | UTCOsimertinib in Resected EGFR-Mutated Non–Small-Cell Lung Cancer – New England Journal of Medicine
A systematic review of rehabilitation and exercise recommendations in oncology guidelines
29 Oct, 2020 | 09:02h | UTC
Commentary on Twitter
Improving the integration of rehabilitation into cancer care: A review of #oncology guidelines and their recommendations for #rehabilitation and #exercise https://t.co/QRerXhhGON #cancerehab #exerciseoncology @NicoleStoutPT @JulieSilverMD @KarenPhysio @DR_SantaMina @WVUCancer pic.twitter.com/kObsSMRN9A
— CA: A Cancer Journal for Clinicians (@CAonline) October 27, 2020
USPSTF draft statement now recommends starting colorectal cancer screening at 45
28 Oct, 2020 | 08:57h | UTCDraft Recommendation Statement: Colorectal Cancer Screening – U.S. Preventive Services Task Force
Commentaries: Colorectal cancer screening should start five years earlier — at 45 — expert panel says – STAT AND USPSTF Lowers Colorectal Cancer Screening Age to 45 in Draft Recommendation – NEJM Journal Watch
Clinical review: New advances in the diagnosis and management of hepatocellular carcinoma
28 Oct, 2020 | 08:47h | UTCNew advances in the diagnosis and management of hepatocellular carcinoma – The BMJ (free for a limited period)
Commentary on Twitter
Hepatocellular carcinoma is one of the leading causes of cancer related death in the world. Here's a comprehensive and evidence based review of the most recent advances in its surveillance, diagnosis, and treatment #BMJEducationhttps://t.co/zks9enDz76
— The BMJ (@bmj_latest) October 26, 2020
Radiation therapy for rectal cancer: Executive summary of an ASTRO clinical practice guideline
28 Oct, 2020 | 08:45h | UTCCommentaries: ASTRO issues clinical guideline on radiation therapy for rectal cancer AND ASTRO Issues Guideline on Radiation Therapy for Rectal Cancer – Physician’s Weekly
Commentary on Twitter
ASTRO issues clinical guideline on #RadiationTherapy for #RectalCancer. Recommendations address #patient selection and treatment techniques for locally advanced disease. This new guideline is published in the #PracticalRO Journal: https://t.co/Q6BDPAOxRI #RadOnc pic.twitter.com/9Zzj5BWA2o
— ASTRO (@ASTRO_org) October 21, 2020
ASCO Guideline Update: Selection of optimal adjuvant chemotherapy and targeted therapy for early breast cancer
27 Oct, 2020 | 09:32h | UTC
Meta-analysis: Evaluating prophylactic heparin in ambulatory patients with solid tumors
22 Oct, 2020 | 09:23h | UTCEvaluating prophylactic heparin in ambulatory patients with solid tumours: a systematic review and individual participant data meta-analysis – The Lancet Haematology (free registration required)
COVID-19 and cancer: Current challenges and perspectives
14 Oct, 2020 | 09:35h | UTCCOVID-19 and Cancer: Current Challenges and Perspectives – Cancer Cell
Trends in clinical profiles, organ support use and outcomes of patients with cancer requiring unplanned ICU admission: a multicenter cohort study
12 Oct, 2020 | 00:31h | UTC
Commentary on Twitter
Read @f_g_zampieri et al: #ICU: a place for complex #oncology patients? outcomes of critically ills w cancer improved in past 8y
> 30% bed/days use
reduced mortality/ICU LOS
-> improved overall care?
Open #FOAMcc on @yourICM at https://t.co/lUKQsZvLcR#CCCF2020 @Dr_Cit https://t.co/8R8lDKEZal pic.twitter.com/VJ5XZLoVrA— Intens Care Med (@yourICM) October 7, 2020
Delivering cancer care during the covid-19 pandemic: recommendations and lessons learned from ASCO global webinars
2 Oct, 2020 | 09:19h | UTC
[Abstract Only] Atezolizumab for first-line treatment of PD-L1–selected patients with non–small-cell lung cancer
1 Oct, 2020 | 08:53h | UTCCommentary: Atezolizumab Leads to Longer OS for Some Types of Advanced NSCLC, Study Says – AJMC
[Abstract Only] Meta-analysis: Adjuvant vs. early salvage radiotherapy for the treatment of localized and locally advanced prostate cancer
29 Sep, 2020 | 10:04h | UTCCommentaries: For Radiotherapy After Radical Prostatectomy, Salvage Therapy Should Be “Standard of Care” – NEJM Journal Watch AND Prostate cancer patients could be spared radiotherapy after surgery as new research suggests there is no benefit and it could be carried out later if the disease comes back – The Daily Mail
Randomized trials: Salvage radiotherapy vs. adjuvant radiotherapy after radical prostatectomy
29 Sep, 2020 | 10:03h | UTCRelated articles: Adjuvant radiotherapy versus early salvage radiotherapy plus short-term androgen deprivation therapy in men with localised prostate cancer after radical prostatectomy (GETUG-AFU 17): a randomised, phase 3 trial – The Lancet Oncology (free registration required) AND Adjuvant radiotherapy versus early salvage radiotherapy following radical prostatectomy (TROG 08.03/ANZUP RAVES): a randomised, controlled, phase 3, non-inferiority trial – The Lancet Oncology (free registration required)
Commentaries: For Radiotherapy After Radical Prostatectomy, Salvage Therapy Should Be “Standard of Care” – NEJM Journal Watch AND Prostate cancer patients could be spared radiotherapy after surgery as new research suggests there is no benefit and it could be carried out later if the disease comes back – The Daily Mail
[Abstract Only] Meta-analysis: Direct oral anticoagulants for cancer-associated venous thromboembolism
28 Sep, 2020 | 01:22h | UTC
Advanced Prostate Cancer: AUA/ASTRO/SUO Guidelines
24 Sep, 2020 | 09:15h | UTCAdvanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART I – The Journal of Urology
Advanced Prostate Cancer: AUA/ASTRO/SUO Guideline PART II – The Journal of Urology
Clinical review: Emerging immunotherapies in multiple myeloma
23 Sep, 2020 | 14:33h | UTCEmerging immunotherapies in multiple myeloma – The BMJ
Commentary on Twitter
Despite advances in treatment in the past 20yrs, multiple myeloma remains an incurable disease. This review summarizes the evidence of these various immunotherapies, their mechanism of action, and data on treatments' safety and efficacy #BMJEducation https://t.co/JWeMlJ89YR
— The BMJ (@bmj_latest) September 22, 2020
[ESMO2020 press release – Not published yet] Randomized trial: No benefit for post-operative radiotherapy in non-small-cell lung cancer
22 Sep, 2020 | 09:23h | UTCCommentary: Phase 3 Trial Results Do Not Support PORT in Resected Stage IIIAN2 NSCLC – Targeted Oncology