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Oncology (all articles)

Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomized trials.

15 Oct, 2021 | 02:07h | UTC

Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomised trials – The Lancet Oncology

 

Commentary on Twitter

 


Systematic Review: Direct oral anticoagulants (DOACs) may be beneficial for people being treated for cancer who have no therapeutic or prophylactic indication for anticoagulation.

14 Oct, 2021 | 09:44h | UTC

Oral anticoagulation in people with cancer who have no therapeutic or prophylactic indication for anticoagulation – Cochrane Library

 


Systematic Review: Music interventions may have beneficial effects on anxiety, depression, hope, pain, and fatigue in adults with cancer.

14 Oct, 2021 | 09:43h | UTC

Music interventions for improving psychological and physical outcomes in people with cancer – Cochrane Library

 


RCT: Among patients with metastatic colorectal cancer, those randomized to systemic treatment alone had lower sixty-day mortality compared to those randomized to primary tumor resection followed by systemic treatment.

12 Oct, 2021 | 00:01h | UTC

Sixty-Day Mortality of Patients With Metastatic Colorectal Cancer Randomized to Systemic Treatment vs Primary Tumor Resection Followed by Systemic Treatment: The CAIRO4 Phase 3 Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Editorial: Primary Tumor Resection and Patients With Asymptomatic Colorectal Cancer and Nonresectable Metastases: Results of Recent Randomized Trials – JAMA Surgery (free for a limited period)

Commentary: Systemic Therapy Alone Bests Surgical Tx for Metastatic CRC – BreakingMed

 

Commentary on Twitter

 


Position statement on percutaneous ablation of non-small cell lung cancer and metastatic disease to the lungs.

8 Oct, 2021 | 10:12h | UTC

Society of Interventional Radiology Multidisciplinary Position Statement on Percutaneous Ablation of Non-small Cell Lung Cancer and Metastatic Disease to the Lungs – Journal of Vascular and Interventional Radiology

Commentary: Society of Interventional Radiology issues guidance for minimally invasive lung cancer treatments – Health Imaging

 


Deprescribing in palliative patients with cancer: a concise review of tools and guidelines.

8 Oct, 2021 | 10:07h | UTC

Deprescribing in palliative patients with cancer: a concise review of tools and guidelines – Supportive Care in Cancer

 


Nephrotoxicity of cancer therapeutic drugs: Focusing on novel agents.

7 Oct, 2021 | 10:14h | UTC

Nephrotoxicity of cancer therapeutic drugs: Focusing on novel agents – Kidney Research and Clinical Practice

 


Cohort Study: Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumor types in 61 countries.

6 Oct, 2021 | 10:09h | UTC

Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study – The Lancet Oncology

 

Commentary on Twitter (thread – click for more)

 


SILENCE Randomized Trial: In patients at the end of life, prophylactic subcutaneous scopolamine butylbromide reduces the occurrence of the death rattle (noisy breathing caused by mucus in the upper respiratory tract).

6 Oct, 2021 | 09:54h | UTC

Effect of Prophylactic Subcutaneous Scopolamine Butylbromide on Death Rattle in Patients at the End of LifeThe SILENCE Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Preventing Death Rattle With Prophylactic Subcutaneous Scopolamine Butylbromide – JAMA (free for a limited period)

Author interview: Scopolamine Butylbromide for Preventing End-of-Life Death Rattle – JAMA

 

Commentary on Twitter

 


The diagnosis and management of endocrine side effects of immune checkpoint inhibitors.

6 Oct, 2021 | 08:44h | UTC

The Diagnosis and Management of Endocrine Side Effects of Immune Checkpoint Inhibitors – Deutsches Ärzteblatt International

Related: Review: Endocrine complications of immunotherapies

 


WHO prioritizes access to diabetes and cancer treatments in new Essential Medicines Lists.

3 Oct, 2021 | 22:46h | UTC

News Release: WHO prioritizes access to diabetes and cancer treatments in new Essential Medicines Lists – World Health Organization

Report: WHO model list of essential medicines – 22nd list, 2021 – World Health Organization

Commentary: For the first time, WHO committee recommends action on high-priced essential medicines – STAT

 

Commentary on Twitter (thread – click for more)

 


Systematic Review: Does testing for cancer in people with unprovoked blood clots in the legs and lungs reduce cancer- and blood clot-related death and illness?

3 Oct, 2021 | 22:33h | UTC

Summary: Does testing for cancer in people with unprovoked blood clots in the legs and lungs reduce cancer- and blood clot-related death and illness? – Cochrane Library

Original article: Effect of testing for cancer on cancer‐ or venous thromboembolism (VTE)‐related mortality and morbidity in people with unprovoked VTE – Cochrane Library

 


Cohort Study: Women treated with radiation therapy for left-sided breast cancer had over twice the risk of subsequent coronary artery disease compared with women treated with radiation therapy for right-sided breast cancer.

1 Oct, 2021 | 10:21h | UTC

Coronary Artery Disease in Young Women After Radiation Therapy for Breast Cancer: The WECARE Study – JACC: CardioOncology

Commentaries:

Left Breast Radiation Therapy Doubles CV Disease Risk vs. Right Breast Radiation Therapy in Young Women – American College of Cardiology

CAD in Young Women After Radiation Therapy for Breast Cancer – American College of Cardiology

 

Commentary on Twitter

 


Bone sarcomas: ESMO–EURACAN–GENTURIS–ERNPaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up.

1 Oct, 2021 | 09:57h | UTC

Bone sarcomas: ESMO–EURACAN–GENTURIS–ERNPaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up – Annals of Oncology

 


Review: Recent Advances in the Management of Metastatic Prostate Cancer

1 Oct, 2021 | 09:55h | UTC

Recent Advances in the Management of Metastatic Prostate Cancer – JCO Oncology Practice

 


RCT: Neurolytic splanchnic nerve block and pain relief, survival, and quality of life in unresectable pancreatic cancer.

30 Sep, 2021 | 10:16h | UTC

Neurolytic Splanchnic Nerve Block and Pain Relief, Survival, and Quality of Life in Unresectable Pancreatic Cancer: A Randomized Controlled Trial – Anesthesiology

 

Commentary on Twitter

 


Gastrointestinal stromal tumors: ESMO–EURACAN–GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up.

30 Sep, 2021 | 10:11h | UTC

Gastrointestinal stromal tumours: ESMO–EURACAN–GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up – Annals of Oncology

 


NCCN Guideline: Older Adult Oncology

30 Sep, 2021 | 09:59h | UTC

NCCN Guidelines® Insights: Older Adult Oncology, Version 1.2021 – Journal of the National Comprehensive Cancer Network

 


RCT: Overall survival benefit with Tebentafusp in metastatic uveal melanoma.

28 Sep, 2021 | 09:03h | UTC

Overall Survival Benefit with Tebentafusp in Metastatic Uveal Melanoma – New England Journal of Medicine

 

Commentary on Twitter

 


Podcast: Neutropenic Fever.

28 Sep, 2021 | 08:52h | UTC

#288 LIVE! Neutropenic Fever featuring Dr. Susan Seo – The Curbsiders

 


RCT: Pembrolizumab for persistent, recurrent, or metastatic cervical cancer.

26 Sep, 2021 | 21:43h | UTC

Pembrolizumab for Persistent, Recurrent, or Metastatic Cervical Cancer – New England Journal of Medicine

Commentary: KEYNOTE-826: Pembrolizumab Plus Chemotherapy in Advanced Cervical Cancer – The ASCO Post

 


Clinical Review on the Management of Metastatic Renal Cell Carcinoma.

26 Sep, 2021 | 21:41h | UTC

Clinical Review on the Management of Metastatic Renal Cell Carcinoma – JCO Oncology Practice

 


M-A: Treatment options for progression or recurrence of glioblastoma.

26 Sep, 2021 | 21:34h | UTC

Treatment options for progression or recurrence of glioblastoma: a network meta‐analysis – Cochrane Library

Summary: Treatment options for people with recurrent and progressive glioblastoma – Cochrane Library

 


Clinical practice guideline on immune checkpoint inhibitor-related adverse events.

24 Sep, 2021 | 08:55h | UTC

Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune checkpoint inhibitor-related adverse events – Journal for ImunoTherapy of Cancer

Related:

NCCN Guidelines Insights: Management of Immunotherapy-Related Toxicities (several resources on the subject)

Immune Checkpoint Inhibitor Myocarditis: Pathophysiological Characteristics, Diagnosis, and Treatment (several resources on the subject)

 


Consensus Document: Evaluation and management of cancer patients presenting with acute cardiovascular disease—Part 1: acute coronary syndromes and acute pericardial diseases.

23 Sep, 2021 | 10:01h | UTC

Evaluation and management of cancer patients presenting with acute cardiovascular disease: a Consensus Document of the Acute CardioVascular Care (ACVC) association and the ESC council of Cardio-Oncology—Part 1: acute coronary syndromes and acute pericardial diseases – European Heart Journal. Acute Cardiovascular Care

Related:

Brazilian Cardio-oncology Guideline – 2020

AHA Scientific Statement: Recognition, prevention, and management of arrhythmias and autonomic disorders in cardio-oncology.

ESMO Consensus Recommendations: Management of Cardiac Disease in Cancer Patients Throughout Oncological Treatment

Cardio-Oncology: Vascular and Metabolic Perspectives: A Scientific Statement from the American Heart Association – Circulation

Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline

Cardio-Onco-Hematology in Clinical Practice. Position Paper and Recommendations – Revista Espanola de Cardiologia (free)

AHA Statement: Cardio-Oncology Rehabilitation to Manage Cardiovascular Outcomes in Cancer Patients and Survivors

 

Commentary on Twitter

 


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