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Oncology (All Articles)

Oncology Medical Home: ASCO and COA Standards – “The OMH model is a system of care delivery that features coordinated, efficient, accessible, and evidence-based care and includes a process for measurement of outcomes to facilitate continuous quality improvement”.

22 Jul, 2021 | 10:49h | UTC

Oncology Medical Home: ASCO and COA Standards – JCO Oncology Practice

Commentary: Oncology Organizations Release New Standards for Medical Home Care – Pharmacy Times

 

RCT: Sintilimab plus a bevacizumab biosimilar versus sorafenib in unresectable hepatocellular carcinoma.

22 Jul, 2021 | 10:47h | UTC

Sintilimab plus a bevacizumab biosimilar (IBI305) versus sorafenib in unresectable hepatocellular carcinoma (ORIENT-32): a randomised, open-label, phase 2–3 study – The Lancet Oncology (link to abstract – $ for full-text)

Commentary: Sintilimab Plus Bevacizumab Biosimilar vs Sorafenib in Unresectable or Metastatic HBV-Associated Hepatocellular Carcinoma – The ASCO Post

 

Commentary on Twitter

 

Systematic review: Breast Reconstruction After Mastectomy.

22 Jul, 2021 | 10:45h | UTC

Breast Reconstruction After Mastectomy – Agency for Healthcare Research and Quality

 

RCT: Central venous access devices (Hickman catheters vs. PICCs vs. PORTs) for the delivery of systemic anticancer therapy – “PORTs are more effective and safer than both Hickman and PICCs”.

21 Jul, 2021 | 10:42h | UTC

Central venous access devices for the delivery of systemic anticancer therapy (CAVA): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)

News release: Study highlights more effective and safe way to deliver chemotherapy – University of Glasgow

 

AGA Clinical Practice Update on Chemoprevention for Colorectal Neoplasia.

16 Jul, 2021 | 10:46h | UTC

AGA Clinical Practice Update on Chemoprevention for Colorectal Neoplasia: Expert Review – Clinical Gastroenterology and Hepatology

 

Commentary on Twitter

 

Radiation therapy-associated toxicity: Etiology, management, and prevention.

15 Jul, 2021 | 09:13h | UTC

Radiation therapy-associated toxicity: Etiology, management, and prevention – CA: A Cancer Journal for Clinicians

 

US Report: Death rates are declining for many common cancers, including lung cancer and melanoma.

15 Jul, 2021 | 09:11h | UTC

Report: Annual Report to the Nation on the Status of Cancer, Part 1: National Cancer Statistics – JNCI: Journal of the National Cancer Institute

News release: Annual Report to the Nation: Rapid decrease in lung cancer and melanoma deaths lead overall continued decline in cancer death rate – National Cancer Institute

Commentaries: Death rates are declining for many common cancers in the U.S., report finds – STAT AND Annual report to the nation: Rapid decrease in lung cancer and melanoma deaths – American Cancer Society

 

Global burden of cancer attributable to alcohol consumption – “Globally, an estimated 741.300, or 4·1% of all new cases of cancer in 2020 were attributable to alcohol consumption”.

14 Jul, 2021 | 11:07h | UTC

Global burden of cancer in 2020 attributable to alcohol consumption: a population-based study – The Lancet Oncology

News release: Alcohol consumption linked to more than 740,000 new cancer cases in 2020 – The Lancet

Commentaries: Alcohol caused 740,000 cancer cases globally last year – study – The Guardian AND Expert reaction to study of alcohol and cancer – Science Media Centre

 

RCT: Long-term efficacy of neoadjuvant chemoradiotherapy plus surgery for the treatment of locally advanced esophageal squamous cell carcinoma.

13 Jul, 2021 | 09:20h | UTC

Long-term Efficacy of Neoadjuvant Chemoradiotherapy Plus Surgery for the Treatment of Locally Advanced Esophageal Squamous Cell Carcinoma: The NEOCRTEC5010 Randomized Clinical Trial – JAMA Surgery

Commentary: Neoadjuvant chemoradiotherapy plus surgery increases overall survival of patients with advanced esophageal squamous cell carcinoma compared to surgery alone – 2 Minute Medicine

 

Commentary on Twitter

 

RCT: MRI can cut overdiagnoses in prostate-cancer screening by half.

9 Jul, 2021 | 10:03h | UTC

MRI-Targeted or Standard Biopsy in Prostate Cancer Screening – New England Journal of Medicine (link to abstract – $ for full-text)

News release: MRI can cut overdiagnoses in prostate-cancer screening by half – Karolinska Institutet

Related articles: RCT: MRI-targeted biopsy safely reduces the need for biopsy in more than one-third of men at risk for prostate cancer AND Meta-Analysis: Negative Predictive Value of MRI in the Detection of Clinically Significant Prostate Cancer AND Study: MRI-Targeted, Systematic, and Combined Biopsy for Prostate Cancer Diagnosis AND Review: The Use of MRI and PET Imaging Studies for Prostate Cancer Management AND Meta-Analysis: MRI plus Targeted Biopsy vs. Systematic Biopsy Alone for the Diagnosis of Prostate Cancer AND Cochrane Review: MRI Pathway vs. Systematic Biopsy for Detecting Prostate Cancer AND Meta-analysis: Clinical Utility of MRI in the Decision-making Process Before Radical Prostatectomy AND Research: Biparametric MRI (simpler, faster) May Be Used to Exclude Aggressive Disease and Avoid Unnecessary Biopsies in Men with Clinical Suspicion of Prostate Cancer AND Research: MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis AND Multiparametric MRI in the Detection of Clinically Significant Prostate Cancer

 

Perspective | Should People With Immune Problems Get Third Vaccine Doses?

8 Jul, 2021 | 09:07h | UTC

Should People With Immune Problems Get Third Vaccine Doses? – The New York Times (a few articles per month are free)

Related: [Preprint] 3rd AstraZeneca shot gives strong immunity. AND Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.

 

Study Commentary: Febrile Neutropenia – Procalcitonin vs. MASCC Score.

8 Jul, 2021 | 08:57h | UTC

Febrile Neutropenia – Procalcitonin vs MASCC Score – Journal Feed

Original study: Prognostic Value of Serum Procalcitonin Levels in Patients With Febrile Neutropenia Presenting to the Emergency Department – The Journal of Emergency Medicine

 

M-A: Pregnancy After Breast Cancer – “These results provide reassuring evidence on the safety of conceiving in BC survivors”.

6 Jul, 2021 | 09:55h | UTC

Pregnancy After Breast Cancer: A Systematic Review and Meta-Analysis – Journal of Clinical Oncology (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Aspirin and cancer survival: a systematic review and meta-analyses of 118 observational studies of aspirin and 18 cancers.

5 Jul, 2021 | 01:42h | UTC

Aspirin and cancer survival: a systematic review and meta-analyses of 118 observational studies of aspirin and 18 cancers – ecancermedicalscience

Commentaries: Expert reaction to review and analysis of observational studies on aspirin and cancer survival – Science Media Centre AND Major review of studies: Aspirin could cut risk of death in cancer patients by 20% – Cardiff University

“It is randomized trials that provide definitive evidence to consider changes to clinical practice. The results of this review provide impetus for cancer patients to consider participation in these trials” (from Science Media Centre)

 

Study Commentary | “Blood test finds 50 types of cancer” – we’ve been down this path before.

5 Jul, 2021 | 01:31h | UTC

“Blood test finds 50 types of cancer” – we’ve been down this path before – HealthNewsReview

Original study: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set – Annals of Oncology

 

RCT: Similar outcomes with 5 vs. 2 years of zoledronate treatment following adjuvant chemotherapy in early breast cancer.

1 Jul, 2021 | 09:50h | UTC

Outcomes With 5 vs 2 Years of Zoledronate Treatment Following Adjuvant Chemotherapy in Early Breast Cancer – The ASCO Post

Original Study: Prognosis of Patients With Early Breast Cancer Receiving 5 Years vs 2 Years of Adjuvant Bisphosphonate Treatment: A Phase 3 Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)

 

Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

1 Jul, 2021 | 09:44h | UTC

Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up – Annals of Oncology

 

Commentary on Twitter

 

Evidence-based clinical practice guidelines for management of colorectal polyps.

25 Jun, 2021 | 10:11h | UTC

Evidence-based clinical practice guidelines for management of colorectal polyps – Journal of Gastroenterology

 

RCT: Lutetium-177–PSMA-617 for metastatic castration-resistant prostate cancer.

24 Jun, 2021 | 09:41h | UTC

Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

 

Risk of atrial fibrillation according to cancer type: a nationwide population-based study – Multiple myeloma showed a higher association with incident AF (aHR: 3.34; 95% CI: 2.98 to 3.75). Esophageal cancer showed the highest risk among solid cancers (aHR: 2.69; 95% CI: 2.45 to 2.95).

21 Jun, 2021 | 08:37h | UTC

Risk of Atrial Fibrillation According to Cancer Type: A Nationwide Population-Based Study – JACC: CardioOncology

 

Commentary on Twitter

 

AHA Scientific Statement: Recognition, prevention, and management of arrhythmias and autonomic disorders in cardio-oncology.

21 Jun, 2021 | 08:38h | UTC

Recognition, Prevention, and Management of Arrhythmias and Autonomic Disorders in Cardio-Oncology: A Scientific Statement From the American Heart Association – Circulation

Commentary: Arrhythmias and Autonomic Dysfunction in the Cancer Patient: Charting a New Path Into the Cardio-oncology Wilderness – American Heart Association

Top Things to Know: Recognition, Prevention, and Management of Arrhythmias and Autonomic Disorders in Cardio-Oncology – American Heart Association

 

Review: venous and arterial thromboembolism in patients with cancer.

16 Jun, 2021 | 08:20h | UTC

Venous and Arterial Thromboembolism in Patients With Cancer: JACC: CardioOncology State-of-the-Art Review

Summary: Venous and Arterial Thromboembolism in Patients With Cancer – American College of Cardiology

 

Viewpoint | Active surveillance as a management option for low-risk basal cell carcinoma.

15 Jun, 2021 | 08:49h | UTC

Active Surveillance as a Management Option for Low-risk Basal Cell Carcinoma – JAMA Internal Medicine

 

Radiology malpractice cases most often involve cancer-related diagnostic errors.

10 Jun, 2021 | 09:27h | UTC

Radiology malpractice cases most often involve cancer-related diagnostic errors – Health Imaging

Original study: Oncologic Errors in Diagnostic Radiology: A 10-Year Analysis Based on Medical Malpractice Claims – Journal of the American College of Radiology (link to abstract – $ for full-text)

 

RCT: Heart-protecting drugs likely unnecessary for most breast cancer patients undergoing adjuvant treatment.

8 Jun, 2021 | 09:15h | UTC

Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy (PRADA) Extended Follow-Up of a 2×2 Factorial, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Candesartan and Metoprolol – Circulation

Commentaries: Heart-protecting drugs likely unnecessary for many breast cancer patients – American College of Cardiology

 

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