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Oncology (All Articles)

Systematic Review: Encephalitis induced by immune checkpoint inhibitors

16 Mar, 2021 | 01:36h | UTC

Encephalitis Induced by Immune Checkpoint Inhibitors: A Systematic Review – JAMA Neurology

 


Perspective | New lung cancer screening guideline comes with many caveats

14 Mar, 2021 | 20:23h | UTC

New lung cancer screening guideline comes with many caveats – Lown Institute

Original Guideline: USPSTF Statement: begin screening for lung cancer at age 50 years instead of 55 years for patients at risk (article and commentaries)

 


Cohort study: Association of ablative radiation therapy with survival among patients with inoperable pancreatic cancer

14 Mar, 2021 | 20:09h | UTC

Association of Ablative Radiation Therapy With Survival Among Patients With Inoperable Pancreatic Cancer – JAMA Oncology (free for a limited period)

 

Commentary on Twitter

 


70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age

14 Mar, 2021 | 20:07h | UTC

70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age – The Lancet Oncology (link to abstract – $ for full-text)

 


Guide to enhanced recovery for cancer patients undergoing breast surgery and reconstruction

14 Mar, 2021 | 20:01h | UTC

Guide to Enhanced Recovery for Cancer Patients Undergoing Breast Surgery and Reconstruction – Annals of Surgical Oncology

Related: Consensus Review of Optimal Perioperative Care in Breast Reconstruction: Enhanced Recovery after Surgery (ERAS) Society Recommendations – Plastic and Reconstructive Surgery

 


Meta-analysis of observational studies suggests better long-term oncologic outcomes with propofol-based total intravenous anesthesia compared to any volatile anesthesia

14 Mar, 2021 | 19:59h | UTC

Anesthesia and Long-term Oncological Outcomes: A Systematic Review and Meta-analysis – Anesthesia & Analgesia

 

Commentary on Twitter

 


NCCN Best Practices Guidance: Management of COVID-19 Infection in Patients with Cancer

12 Mar, 2021 | 08:31h | UTC

NCCN Best Practices Guidance: Management of COVID-19 Infection in Patients with Cancer – National Comprehensive Cancer Network

News release: NCCN Provides New COVID-19 Treatment Advice; Updates Vaccine Guidance for Cancer Patients – National Comprehensive Cancer Network

 


USPSTF Statement: begin screening for lung cancer at age 50 years instead of 55 years for patients at risk

10 Mar, 2021 | 08:28h | UTC

Recommendation Statement: Screening for Lung Cancer – US Preventive Services Task Force

Editorials: Broadened Eligibility for Lung Cancer Screening: Challenges and Uncertainty for Implementation and Equity – JAMA AND Expanded Access to Lung Cancer Screening—Implementing Wisely to Optimize Health – JAMA Network Open AND New USPSTF Guidelines for Lung Cancer Screening: Better but Not Enough – JAMA Surgery AND The 2021 US Preventive Services Task Force Recommendation on Lung Cancer Screening: The More Things Stay the Same… – JAMA Oncology

 


RCT: Secondary cytoreduction followed by chemotherapy vs. chemotherapy alone in platinum-sensitive relapsed ovarian cancer

10 Mar, 2021 | 08:18h | UTC

Secondary cytoreduction followed by chemotherapy versus chemotherapy alone in platinum-sensitive relapsed ovarian cancer (SOC-1): a multicentre, open-label, randomised, phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


RCT: Primary tumor resection plus chemotherapy vs. chemotherapy alone for colorectal cancer patients with asymptomatic, synchronous unresectable metastases

7 Mar, 2021 | 19:23h | UTC

Primary Tumor Resection Plus Chemotherapy Versus Chemotherapy Alone for Colorectal Cancer Patients With Asymptomatic, Synchronous Unresectable Metastases (JCOG1007; iPACS): A Randomized Clinical Trial – Journal of Clinical Oncology

Original study: No Survival Benefit to Primary Resection Before Chemo in Metastatic Colorectal Cancer – Medscape / Reuters

 

 


New WHO/IAEA publication provides guidance on radiotherapy equipment to fight cancer

7 Mar, 2021 | 19:28h | UTC

News Release: New WHO/IAEA publication provides guidance on radiotherapy equipment to fight cancer – World Health Organization

Technical Document: Technical specifications of radiotherapy equipment for cancer treatment

 

 


Study: Cancer patients benefit from using automated device to manage their symptoms

7 Mar, 2021 | 19:21h | UTC

Cancer patients benefit from using automated device to manage their symptoms – News Medical / University of Leeds

Original study: Phase III Randomized Controlled Trial of eRAPID: eHealth Intervention During Chemotherapy – Journal of Clinical Oncology

Editorial: Benefits of Digital Symptom Monitoring With Patient-Reported Outcomes During Adjuvant Cancer Treatment – Journal of Clinical Oncology

 


Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance

5 Mar, 2021 | 08:35h | UTC

Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance – The BMJ

Recommendations: Pharmacovigilance Evidence Review: The effect of COVID-19 vaccines on breast screening – Drug Safety Research Unit

Related: 2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients

 


ACG Clinical Guidelines: Start colorectal cancer screening at 45

5 Mar, 2021 | 08:31h | UTC

ACG Clinical Guidelines: Colorectal Cancer Screening 2021 – The American Journal of Gastroenterology

Related: USPSTF draft statement now recommends starting colorectal cancer screening at 45

 


Global patterns and trends in incidence and mortality of thyroid cancer in children and adolescents: a population-based study

5 Mar, 2021 | 08:10h | UTC

Global patterns and trends in incidence and mortality of thyroid cancer in children and adolescents: a population-based study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Commentaries: Global thyroid cancer overdiagnosis in children and adolescents – MDEdge (free registration required) AND Global Thyroid Cancer Overdiagnosis in Children and Adolescents – Medscape (free registration required)

 

Commentary on Twitter

 


RCT: Nivolumab plus Cabozantinib vs. Sunitinib for Advanced Renal-Cell Carcinoma

4 Mar, 2021 | 08:33h | UTC

Nivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma – New England Journal of Medicine (link to abstract – $ for full-text)

 


RCT: Effect of Blinatumomab vs. Chemotherapy in children with high-risk first-relapse B-Cell Acute Lymphoblastic Leukemia

3 Mar, 2021 | 08:19h | UTC

Effect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA (free for a limited period)

Related study: Effect of Postreinduction Therapy Consolidation With Blinatumomab vs Chemotherapy on Disease-Free Survival in Children, Adolescents, and Young Adults With First Relapse of B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Blinatumomab for Treatment of Children With High-risk Relapsed B-Cell Acute Lymphoblastic Leukemia – JAMA (free for a limited period)

 


Five-year outcomes from randomized, phase III trials: Nivolumab vs. Docetaxel in previously treated non–small-cell lung cancer

3 Mar, 2021 | 08:10h | UTC

Five-Year Outcomes From the Randomized, Phase III Trials CheckMate 017 and 057: Nivolumab Versus Docetaxel in Previously Treated Non–Small-Cell Lung Cancer – Journal of Clinical Oncology

 

Commentary on Twitter

 


M-A: Local salvage therapies after radiotherapy for prostate cancer

3 Mar, 2021 | 08:06h | UTC

A Systematic Review and Meta-analysis of Local Salvage Therapies After Radiotherapy for Prostate Cancer (MASTER) – European Urology (link to abstract – $ for full-text)

 

Commentary on Twitter (thread – click for more)

 


RCT: Extended vs. limited pelvic lymph node dissection during radical prostatectomy for intermediate- and high-risk prostate cancer

3 Mar, 2021 | 08:05h | UTC

Extended Versus Limited Pelvic Lymph Node Dissection During Radical Prostatectomy for Intermediate- and High-risk Prostate Cancer: Early Oncological Outcomes from a Randomized Phase 3 Trial – European Urology (link to abstract – $ for full-text)

Commentary: Extended pelvic lymph node dissection during RP does not appear beneficial – Urology Times

 

Commentary on Twitter

 


2 Case Series and Guidance| Lymphadenopathy in COVID-19 Vaccine Recipients

28 Feb, 2021 | 21:42h | UTC

Case series: Lymphadenopathy in COVID-19 Vaccine Recipients: Diagnostic Dilemma in Oncology Patients – Radiology

Related case series in women without cancer: Coronavirus Disease (COVID-19) Vaccination Associated Axillary Adenopathy: Imaging Findings and Follow-Up Recommendations in 23 Women – American Journal of Roentgenology

Related guidance 1: Multidisciplinary Recommendations Regarding Post-Vaccine Adenopathy and Radiologic Imaging: Radiology Scientific Expert Panel – Radiology

Related guidance 2: Mitigating the Impact of Coronavirus Disease (COVID-19) Vaccinations on Patients Undergoing Breast Imaging Examinations: A Pragmatic Approach – American Journal of Roentgenology AND Commentary: What to do when a mammogram shows swollen lymph nodes in women just vaccinated for COVID – Massachusetts General Hospital

Commentary: COVID-19 vaccine affects imaging results, researchers warn – AuntMinnie (free registration required)

 


New report reviews methods for reducing waste, improving efficiency with expensive injectable medications

28 Feb, 2021 | 21:29h | UTC

New Report Reviews Methods for Reducing Waste, Improving Efficiency With Expensive Injectable Medications – The ASCO Post

Summary: Medications in Single-Dose Vials and Implications of Discarded Injectable Drugs: A National Academies Report – JAMA

Original report: Medications in Single Dose Vials: Implications of Discarded Drugs (2021) – National Academies of Sciences, Engineering, and Medicine

 

Commentary on Twitter

 


RCT: Endoscopic surgery improves survival compared with intensity-modulated radiotherapy in resectable locally recurrent nasopharyngeal carcinoma

28 Feb, 2021 | 20:45h | UTC

Endoscopic surgery compared with intensity-modulated radiotherapy in resectable locally recurrent nasopharyngeal carcinoma: a multicentre, open-label, randomised, controlled, phase 3 trial – The Lancet Oncology

Commentary: Endoscopic Nasopharyngectomy vs IMRT for Previously Treated, Resectable, Locally Recurrent Nasopharyngeal Carcinoma – The ASCO Post

 


CAR T-cell therapy produces deep, sustained remissions in patients with relapsed myeloma

26 Feb, 2021 | 08:31h | UTC

CAR T-cell therapy produces deep, sustained remissions in patients with relapsed myeloma – Dana-Farber Cancer Institute

Original study: Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma – New England Journal of Medicine

 


Integrated palliative and oncology care for patients receiving treatment for acute myeloid leukemia

26 Feb, 2021 | 08:25h | UTC

Integrated Palliative and Oncology Care for Patients Receiving Treatment for Acute Myeloid Leukemia – The ASCO Post

Original article: Effectiveness of Integrated Palliative and Oncology Care for Patients With Acute Myeloid Leukemia: A Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)

 


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