Radiology – Breast
RCT | Mammography screening with AI reduces workload by 44.3% without loss in detection efficacy
4 Aug, 2023 | 12:13h | UTCArtificial intelligence-supported screen reading versus standard double reading in the Mammography Screening with Artificial Intelligence trial (MASAI): a clinical safety analysis of a randomised, controlled, non-inferiority, single-blinded, screening accuracy study – The Lancet Oncology (link to abstract – $ for full-text)
News Release: First randomized trial finds AI-supported mammography screening is safe and almost halves radiologist workload – Lancet
Commentaries:
Large Mammography Study Shows Significant Benefits with AI-Aided Screening – Diagnostic Imaging
Review | Ultrasound imaging of the axilla
29 May, 2023 | 10:56h | UTCUltrasound imaging of the axilla – Insights into Imaging
Study suggests that routine axillary scanning in diagnostic breast ultrasound has limited impact on cancer detection
19 Apr, 2023 | 13:06h | UTCTo scan or not to scan: effect of scanning the axilla of all patients undergoing diagnostic breast ultrasound – Clinical Imaging (link to abstract – $ for full-text)
Commentary: Is scanning the axilla during diagnostic breast ultrasound necessary? – Health Imaging
SR | Adding ultrasound to mammography increases breast cancer detection, but increases false-positives and biopsies
3 Apr, 2023 | 13:55h | UTCSummary: The systematic review examined the effectiveness and safety of combining mammography with breast ultrasonography versus mammography alone for breast cancer screening in women at average risk. The research included one randomized controlled trial, two prospective cohort studies, and five retrospective cohort studies, involving a total of 209,207 women.
High certainty evidence from one trial indicated that combining mammography with ultrasonography led to the detection of more breast cancer cases than mammography alone (5 vs. 3 per 1000 women). However, this combination also led to a higher number of false-positive results and biopsies. For every 1000 women screened with the combined approach, 37 more received a false-positive result, and 27 more women underwent a biopsy.
Secondary analysis of the trial data revealed that in women with dense breasts, the combined screening detected more cancer cases than mammography alone, while cohort studies for women with non-dense breasts showed no statistically significant difference between the two screening methods.
The included studies did not analyze whether the higher number of detected cancers with the combined screening method resulted in lower mortality rates compared to mammography alone. Further research, including randomized controlled trials or prospective cohort studies with longer observation periods, is needed to assess the impact of the two screening interventions on morbidity and mortality.
M-A | Supplemental breast cancer screening in women with dense breasts and negative mammography
10 Mar, 2023 | 14:12h | UTCSupplemental Breast Cancer Screening in Women with Dense Breasts and Negative Mammography: A Systematic Review and Meta-Analysis – Radiology (link to abstract – $ for full-text)
News Release: Breast MRI effective at detecting cancer in dense breasts – Radiological Society of North America
Commentary on Twitter
Compared with other supplemental modalities, MRI was superior in detecting breast cancer in a systematic review and meta-analysis. @JDMIRadiologist @UHN @UHN_Research https://t.co/NiZIFO5z9K pic.twitter.com/f9xzVXN9LJ
— Radiology (@radiology_rsna) February 1, 2023
RCT | Preoperative MRI in breast cancer did not influence local relapse-free survival, overall survival, or reoperation rates
15 Feb, 2023 | 15:57h | UTCSummary: This study investigated the impact of preoperative magnetic resonance imaging (MRI) on survival and surgical outcomes in conservative surgery for breast cancer. The randomized controlled trial included female participants with stage 0-III breast cancer, eligible for breast-conserving surgery. The study found that preoperative MRI increased the rate of mastectomies by 8% compared to routine radiologic exams using mammography and ultrasound. However, preoperative MRI did not impact the rates of local relapse-free survival, overall survival, or reoperation.*
*Note: This summary was created through the collaboration of a medical editor and ChatGPT.
Cohort Study: Association of screening with digital breast tomosynthesis vs. digital mammography with risk of interval invasive and advanced breast cancer.
17 Jun, 2022 | 11:09h | UTCAssociation of Screening With Digital Breast Tomosynthesis vs Digital Mammography With Risk of Interval Invasive and Advanced Breast Cancer – JAMA (free for a limited period)
Editorial: Digital Breast Tomosynthesis and Detection of Interval Invasive and Advanced Breast Cancers – JAMA (free for a limited period)
News Release: 3-D Mammography Technique Benefits Some Women, Not All – University of California San Francisco
Regional lymphadenopathy following COVID-19 vaccination in patients with or suspicious of breast cancer: a quick summary of current key facts and recommendations.
14 Jun, 2022 | 11:07h | UTCRelated:
2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients
Recommendations for breast cancer screening in women with extremely dense breasts.
4 May, 2022 | 08:11h | UTC
RCT: Digital breast tomosynthesis plus synthesized mammography versus digital screening mammography for the detection of invasive breast cancer.
1 May, 2022 | 23:14h | UTCDigital breast tomosynthesis plus synthesised mammography versus digital screening mammography for the detection of invasive breast cancer (TOSYMA): a multicentre, open-label, randomised, controlled, superiority trial – The Lancet Oncology (link to abstract – $ for full-text)
Review | Breast MRI during pregnancy and lactation: clinical challenges and technical advances.
14 Apr, 2022 | 07:57h | UTC
Artificial intelligence evaluation of 122 969 mammography examinations from a population-based screening program.
30 Mar, 2022 | 08:49h | UTCNews Release: AI shows potential in breast cancer screening programs – Radiological Society of North America
Cohort Study | Breast arterial calcification: a novel cardiovascular risk enhancer among postmenopausal women.
16 Mar, 2022 | 09:56h | UTCBreast Arterial Calcification: a Novel Cardiovascular Risk Enhancer Among Postmenopausal Women – Circulation: Cardiovascular Imaging (link to abstract – $ for full-text)
News Release: Mammograms may provide clues about women’s risk for cardiovascular disease – AHA Newsroom
Commentaries:
More Evidence Links Breast Arterial Calcification and CVD Risk – TCTMD
Breast Arterial Calcification on Mammography Tied to CVD Risk – HealthDay
Related: Review: Role of Breast Arterial Calcification for Cardiovascular Risk Stratification in Women
Retrospective Cohort Study: Frequency and outcomes of MRI-detected axillary adenopathy following COVID-19 vaccination.
11 Mar, 2022 | 10:05h | UTCRelated:
2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients
Screening Algorithms in Dense Breasts: AJR Expert Panel Narrative Review.
24 Feb, 2022 | 10:11h | UTC
Guideline: Recommendations on Breast Ultrasound – Part I – Examination technique, ultrasound criteria, and documentation.
16 Feb, 2022 | 08:27h | UTC
Systematic review finds there is insufficient evidence that AI breast cancer screening is accurate enough to replace human scrutiny.
10 Sep, 2021 | 05:12h | UTCOriginal study: Use of artificial intelligence for image analysis in breast cancer screening programmes: systematic review of test accuracy – The BMJ
Commentary on Twitter
A systematic review of #AI for mammography is very disappointing
"Thirty four (94%) of 36 AI systems evaluated in these studies were less accurate than a single radiologist, and all were less accurate than consensus of two or more radiologists"https://t.co/zqFTxojU9J @bmj_latest pic.twitter.com/wylwOsf4ua— Eric Topol (@EricTopol) September 2, 2021
Axillary lymphadenopathy at the time of COVID-19 vaccination: ten recommendations from the European Society of Breast Imaging.
25 Aug, 2021 | 08:59h | UTCRelated:
2 Case Series and Guidance| Lymphadenopathy in COVID-19 Vaccine Recipients
COVID-19 vaccine-linked adenopathies could mimic breast malignancies
Mammographic features are associated with cardiometabolic disease risk and mortality.
6 Aug, 2021 | 09:04h | UTC
Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance
5 Mar, 2021 | 08:35h | UTCRecommendations: Pharmacovigilance Evidence Review: The effect of COVID-19 vaccines on breast screening – Drug Safety Research Unit
Related: 2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients
2 Case Series and Guidance| Lymphadenopathy in COVID-19 Vaccine Recipients
28 Feb, 2021 | 21:42h | UTCCase series: Lymphadenopathy in COVID-19 Vaccine Recipients: Diagnostic Dilemma in Oncology Patients – Radiology
Related case series in women without cancer: Coronavirus Disease (COVID-19) Vaccination Associated Axillary Adenopathy: Imaging Findings and Follow-Up Recommendations in 23 Women – American Journal of Roentgenology
Related guidance 1: Multidisciplinary Recommendations Regarding Post-Vaccine Adenopathy and Radiologic Imaging: Radiology Scientific Expert Panel – Radiology
Related guidance 2: Mitigating the Impact of Coronavirus Disease (COVID-19) Vaccinations on Patients Undergoing Breast Imaging Examinations: A Pragmatic Approach – American Journal of Roentgenology AND Commentary: What to do when a mammogram shows swollen lymph nodes in women just vaccinated for COVID – Massachusetts General Hospital
Commentary: COVID-19 vaccine affects imaging results, researchers warn – AuntMinnie (free registration required)
Cost-effective analysis suggests incorporating baseline breast density at 40 years to determine the frequency of screening in women at average risk for breast cancer
10 Feb, 2021 | 01:37h | UTCIncorporating Baseline Breast Density When Screening Women at Average Risk for Breast Cancer: A Cost-Effectiveness Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Screening based on breast density at age 40 may reduce breast cancer mortality – ACP Internist AND Screening strategy based on baseline breast density at age 40 may be effective for reducing breast cancer mortality – American College of Physicians AND For Mammography: Baseline at 40 Makes Sense – Diagnostic Imaging
Commentary on Twitter
New research led by @TinaShihHSR of @MDAndersonNews found screening strategy based on baseline breast density at age 40 may be effective and cost-effective for reducing #breastcancer mortality https://t.co/9f0P7CSCmD. pic.twitter.com/PemE8XVSqr
— Annals of Int Med (@AnnalsofIM) February 9, 2021
PET imaging reveals which breast cancer patients won’t respond to hormone therapy
10 Feb, 2021 | 01:09h | UTC
COVID-19 vaccine-linked adenopathies could mimic breast malignancies
2 Feb, 2021 | 01:17h | UTCCOVID-19 Vaccine-Linked Adenopathies Could Mimic Breast Malignancies – Diagnostic Imaging
Original Study: Unilateral axillary Adenopathy in the setting of COVID-19 vaccine – Clinical Imaging
Commentaries on Twitter
Important for radiologists to consider vaccine induced hyperplastic adenopathy in unilateral axillary adenopathy seen on #breastimaging post #COVID19Vaccine #COVID19
Read here https://t.co/7IizHgIzU0@NishiMehtaMD @KatiaDodelzon @KemiMDRad @WCMRadiology @BreastImaging
— Clinical Imaging (@CI_Journal) January 19, 2021
The COVID-19 vaccine may cause swollen lymph nodes that could be mistaken for breast malignancies. However, it's important not to postpone your vaccine or breast cancer screenings, researchers from @WCMRadiology and @WCMBreastCenter say. https://t.co/jLuVbA2rXL
— Weill Cornell Medicine (@WeillCornell) January 22, 2021
Consensus statement recommends individualizing surveillance mammography for older patients after treatment for early-stage breast cancer
1 Feb, 2021 | 01:33h | UTCCommentaries: First Mammography Guidelines Released for Older Breast Cancer Survivors – Diagnostic Imaging AND New Surveillance Mammography Screening Guidelines Issued for Breast Cancer Survivors Aged 75 and Older – The ASCO Post