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Radiology – Breast

RCT | Mammography screening with AI reduces workload by 44.3% without loss in detection efficacy

4 Aug, 2023 | 12:13h | UTC

Artificial intelligence-supported screen reading versus standard double reading in the Mammography Screening with Artificial Intelligence trial (MASAI): a clinical safety analysis of a randomised, controlled, non-inferiority, single-blinded, screening accuracy study – The Lancet Oncology (link to abstract – $ for full-text)

News Release: First randomized trial finds AI-supported mammography screening is safe and almost halves radiologist workload – Lancet

Commentaries:

Large Mammography Study Shows Significant Benefits with AI-Aided Screening – Diagnostic Imaging

Expert reaction to interim safety analysis of randomised trial on AI-supported mammography screening – Science Media Centre

 


Review | Ultrasound imaging of the axilla

29 May, 2023 | 10:56h | UTC

Ultrasound imaging of the axilla – Insights into Imaging

 


Study suggests that routine axillary scanning in diagnostic breast ultrasound has limited impact on cancer detection

19 Apr, 2023 | 13:06h | UTC

To scan or not to scan: effect of scanning the axilla of all patients undergoing diagnostic breast ultrasound – Clinical Imaging (link to abstract – $ for full-text)

Commentary: Is scanning the axilla during diagnostic breast ultrasound necessary? – Health Imaging

 


SR | Adding ultrasound to mammography increases breast cancer detection, but increases false-positives and biopsies

3 Apr, 2023 | 13:55h | UTC

Summary: The systematic review examined the effectiveness and safety of combining mammography with breast ultrasonography versus mammography alone for breast cancer screening in women at average risk. The research included one randomized controlled trial, two prospective cohort studies, and five retrospective cohort studies, involving a total of 209,207 women.

High certainty evidence from one trial indicated that combining mammography with ultrasonography led to the detection of more breast cancer cases than mammography alone (5 vs. 3 per 1000 women). However, this combination also led to a higher number of false-positive results and biopsies. For every 1000 women screened with the combined approach, 37 more received a false-positive result, and 27 more women underwent a biopsy.

Secondary analysis of the trial data revealed that in women with dense breasts, the combined screening detected more cancer cases than mammography alone, while cohort studies for women with non-dense breasts showed no statistically significant difference between the two screening methods.

The included studies did not analyze whether the higher number of detected cancers with the combined screening method resulted in lower mortality rates compared to mammography alone. Further research, including randomized controlled trials or prospective cohort studies with longer observation periods, is needed to assess the impact of the two screening interventions on morbidity and mortality.

Article: Mammography in combination with breast ultrasonography versus mammography for breast cancer screening in women at average risk – Cochrane Database of Systematic Reviews

Summary: Mammography followed by ultrasonography compared to mammography alone for breast cancer screening in women at average risk of breast cancer – Cochrane Database of Systematic Reviews

 


M-A | Supplemental breast cancer screening in women with dense breasts and negative mammography

10 Mar, 2023 | 14:12h | UTC

Supplemental Breast Cancer Screening in Women with Dense Breasts and Negative Mammography: A Systematic Review and Meta-Analysis – Radiology (link to abstract – $ for full-text)

News Release: Breast MRI effective at detecting cancer in dense breasts – Radiological Society of North America

Commentary: Study Finds Breast MRI Superior vs Other Supplementary Screening Tests for Detecting Breast Cancer in Patients With Dense Breasts – The ASCO Post

 

Commentary on Twitter

 


RCT | Preoperative MRI in breast cancer did not influence local relapse-free survival, overall survival, or reoperation rates

15 Feb, 2023 | 15:57h | UTC

Summary: This study investigated the impact of preoperative magnetic resonance imaging (MRI) on survival and surgical outcomes in conservative surgery for breast cancer. The randomized controlled trial included female participants with stage 0-III breast cancer, eligible for breast-conserving surgery. The study found that preoperative MRI increased the rate of mastectomies by 8% compared to routine radiologic exams using mammography and ultrasound. However, preoperative MRI did not impact the rates of local relapse-free survival, overall survival, or reoperation.*

Article: Effects of preoperative magnetic resonance image on survival rates and surgical planning in breast cancer conservative surgery: randomized controlled trial (BREAST-MRI trial) – Breast Cancer Research and Treatment

 

*Note: This summary was created through the collaboration of a medical editor and ChatGPT.

 


Cohort Study: Association of screening with digital breast tomosynthesis vs. digital mammography with risk of interval invasive and advanced breast cancer.

17 Jun, 2022 | 11:09h | UTC

Association of Screening With Digital Breast Tomosynthesis vs Digital Mammography With Risk of Interval Invasive and Advanced Breast Cancer – JAMA (free for a limited period)

Editorial: Digital Breast Tomosynthesis and Detection of Interval Invasive and Advanced Breast Cancers – JAMA (free for a limited period)

News Release: 3-D Mammography Technique Benefits Some Women, Not All – University of California San Francisco

 


Regional lymphadenopathy following COVID-19 vaccination in patients with or suspicious of breast cancer: a quick summary of current key facts and recommendations.

14 Jun, 2022 | 11:07h | UTC

Regional Lymphadenopathy Following COVID-19 Vaccination in Patients with or Suspicious of Breast Cancer: A Quick Summary of Current Key Facts and Recommendations – Korean Journal of Radiology

Related:

2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients

Axillary lymphadenopathy at the time of COVID-19 vaccination: ten recommendations from the European Society of Breast Imaging (EUSOBI) – Insights into Imaging

Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance – The BMJ

Frequency and outcomes of MRI-detected axillary adenopathy following COVID-19 vaccination – European Radiology

Regional lymphadenopathy following COVID-19 vaccination: Literature review and considerations for patient management in breast cancer care – European Journal of Cancer

 


Recommendations for breast cancer screening in women with extremely dense breasts.

4 May, 2022 | 08:11h | UTC

Breast cancer screening in women with extremely dense breasts recommendations of the European Society of Breast Imaging (EUSOBI) – European Radiology

 


RCT: Digital breast tomosynthesis plus synthesized mammography versus digital screening mammography for the detection of invasive breast cancer.

1 May, 2022 | 23:14h | UTC

Digital breast tomosynthesis plus synthesised mammography versus digital screening mammography for the detection of invasive breast cancer (TOSYMA): a multicentre, open-label, randomised, controlled, superiority trial – The Lancet Oncology (link to abstract – $ for full-text)

Commentary: Breast Cancer Screening With Digital Breast Tomosynthesis Plus Synthesized Mammography vs Digital Mammography – The ASCO Post

 


Review | Breast MRI during pregnancy and lactation: clinical challenges and technical advances.

14 Apr, 2022 | 07:57h | UTC

Breast MRI during pregnancy and lactation: clinical challenges and technical advances – Insights into Imaging

 


Artificial intelligence evaluation of 122 969 mammography examinations from a population-based screening program.

30 Mar, 2022 | 08:49h | UTC

Artificial Intelligence Evaluation of 122 969 Mammography Examinations from a Population-based Screening Program – Radiology

News Release: AI shows potential in breast cancer screening programs – Radiological Society of North America

 


Cohort Study | Breast arterial calcification: a novel cardiovascular risk enhancer among postmenopausal women.

16 Mar, 2022 | 09:56h | UTC

Breast Arterial Calcification: a Novel Cardiovascular Risk Enhancer Among Postmenopausal Women – Circulation: Cardiovascular Imaging (link to abstract – $ for full-text)

News Release: Mammograms may provide clues about women’s risk for cardiovascular disease – AHA Newsroom

Commentaries:

More Evidence Links Breast Arterial Calcification and CVD Risk – TCTMD

Breast Arterial Calcification on Mammography Tied to CVD Risk – HealthDay

Related: Review: Role of Breast Arterial Calcification for Cardiovascular Risk Stratification in Women

 


Retrospective Cohort Study: Frequency and outcomes of MRI-detected axillary adenopathy following COVID-19 vaccination.

11 Mar, 2022 | 10:05h | UTC

Frequency and outcomes of MRI-detected axillary adenopathy following COVID-19 vaccination – European Radiology

Related:

Regional lymphadenopathy following COVID-19 vaccination: Literature review and considerations for patient management in breast cancer care.

2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients

Axillary lymphadenopathy at the time of COVID-19 vaccination: ten recommendations from the European Society of Breast Imaging.

Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance

 


Screening Algorithms in Dense Breasts: AJR Expert Panel Narrative Review.

24 Feb, 2022 | 10:11h | UTC

Screening Algorithms in Dense Breasts: AJR Expert Panel Narrative Review – American Journal of Roentgenology

 


Guideline: Recommendations on Breast Ultrasound – Part I – Examination technique, ultrasound criteria, and documentation.

16 Feb, 2022 | 08:27h | UTC

Best Practice Guideline – DEGUM Recommendations on Breast Ultrasound – Part I – Examination technique, DEGUM ultrasound criteria, and documentation – Ultraschall in der Medizin

 


Systematic review finds there is insufficient evidence that AI breast cancer screening is accurate enough to replace human scrutiny.

10 Sep, 2021 | 05:12h | UTC

Insufficient evidence that AI breast cancer screening is accurate enough to replace human scrutiny – The BMJ

Original study: Use of artificial intelligence for image analysis in breast cancer screening programmes: systematic review of test accuracy – The BMJ

 

Commentary on Twitter

 


Axillary lymphadenopathy at the time of COVID-19 vaccination: ten recommendations from the European Society of Breast Imaging.

25 Aug, 2021 | 08:59h | UTC

Axillary lymphadenopathy at the time of COVID-19 vaccination: ten recommendations from the European Society of Breast Imaging (EUSOBI) – Insights into Imaging

Related:

Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance

2 Case Series and Guidance| Lymphadenopathy in COVID-19 Vaccine Recipients

COVID-19 vaccine-linked adenopathies could mimic breast malignancies

 


Mammographic features are associated with cardiometabolic disease risk and mortality.

6 Aug, 2021 | 09:04h | UTC

Mammographic features are associated with cardiometabolic disease risk and mortality – European Heart Journal

 


Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance

5 Mar, 2021 | 08:35h | UTC

Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance – The BMJ

Recommendations: Pharmacovigilance Evidence Review: The effect of COVID-19 vaccines on breast screening – Drug Safety Research Unit

Related: 2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients

 


2 Case Series and Guidance| Lymphadenopathy in COVID-19 Vaccine Recipients

28 Feb, 2021 | 21:42h | UTC

Case series: Lymphadenopathy in COVID-19 Vaccine Recipients: Diagnostic Dilemma in Oncology Patients – Radiology

Related case series in women without cancer: Coronavirus Disease (COVID-19) Vaccination Associated Axillary Adenopathy: Imaging Findings and Follow-Up Recommendations in 23 Women – American Journal of Roentgenology

Related guidance 1: Multidisciplinary Recommendations Regarding Post-Vaccine Adenopathy and Radiologic Imaging: Radiology Scientific Expert Panel – Radiology

Related guidance 2: Mitigating the Impact of Coronavirus Disease (COVID-19) Vaccinations on Patients Undergoing Breast Imaging Examinations: A Pragmatic Approach – American Journal of Roentgenology AND Commentary: What to do when a mammogram shows swollen lymph nodes in women just vaccinated for COVID – Massachusetts General Hospital

Commentary: COVID-19 vaccine affects imaging results, researchers warn – AuntMinnie (free registration required)

 


Cost-effective analysis suggests incorporating baseline breast density at 40 years to determine the frequency of screening in women at average risk for breast cancer

10 Feb, 2021 | 01:37h | UTC

Incorporating Baseline Breast Density When Screening Women at Average Risk for Breast Cancer: A Cost-Effectiveness Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Screening based on breast density at age 40 may reduce breast cancer mortality – ACP Internist AND Screening strategy based on baseline breast density at age 40 may be effective for reducing breast cancer mortality – American College of Physicians AND For Mammography: Baseline at 40 Makes Sense – Diagnostic Imaging

 

Commentary on Twitter

 


PET imaging reveals which breast cancer patients won’t respond to hormone therapy

10 Feb, 2021 | 01:09h | UTC

PET Imaging Reveals Which Breast Cancer Patients Won’t Respond to Hormone Therapy – Diagnostic Imaging

Original study: Association of PET-based estradiol-challenge test for breast cancer progesterone receptors with response to endocrine therapy – Nature Communications

 


COVID-19 vaccine-linked adenopathies could mimic breast malignancies

2 Feb, 2021 | 01:17h | UTC

COVID-19 Vaccine-Linked Adenopathies Could Mimic Breast Malignancies – Diagnostic Imaging

Original Study: Unilateral axillary Adenopathy in the setting of COVID-19 vaccine – Clinical Imaging

 

Commentaries on Twitter

 


Consensus statement recommends individualizing surveillance mammography for older patients after treatment for early-stage breast cancer

1 Feb, 2021 | 01:33h | UTC

Individualizing Surveillance Mammography for Older Patients After Treatment for Early-Stage Breast Cancer: Multidisciplinary Expert Panel and International Society of Geriatric Oncology Consensus Statement – JAMA Oncology

Commentaries: First Mammography Guidelines Released for Older Breast Cancer Survivors – Diagnostic Imaging AND New Surveillance Mammography Screening Guidelines Issued for Breast Cancer Survivors Aged 75 and Older – The ASCO Post

 


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