Bioethics | Links Medicus Content Curation & Alerts in Medicine

Ableism in #ICU? ie
➡️ assumption that individuals w disabilities are not capable of making decisions about their own care
➡️ lack of accessibility to adjustments to aid communication
➡️ lack of knowledge/understanding among providers#ICMfromtheInside
🖇️ https://t.co/NvqnoP4FM6 pic.twitter.com/TH16gQOrJo

— Intensive Care Medicine (@yourICM) May 1, 2023

ChatGPT’s responses to patient questions rated higher for quality and empathy than physicians

2 May, 2023 | 14:00h | UTC

ChatGPT’s responses to patient questions rated higher for quality and empathy than physicians

Comparing Physician and Artificial Intelligence Chatbot Responses to Patient Questions Posted to a Public Social Media Forum – JAMA Internal Medicine (free for a limited period)

Commentaries:

How Chatbots and Large Language Model Artificial Intelligence Systems Will Reshape Modern Medicine: Fountain of Creativity or Pandora’s Box? – JAMA Internal Medicine (free for a limited period)

Expert reaction to study comparing physician and AI chatbot responses to patient questions – Science Media Centre

Commentary on Twitter (thread – click for more)

Here's what's under appreciated about Chat GPT paper🧵
PCP panel can be 2 to 5k
Doc in clinic 40 hours++ already
Doc not good at typing
Chat GPT can reply instantly
Chat GPT never fatigues
Can keep replying
Can reply day&night
Can read chart
Can type pleasantries, doc too busy 4

— Vinay Prasad MD MPH (@VPrasadMDMPH) April 30, 2023

Extracorporeal CPR dissemination and integration with organ preservation in the USA: ethical and logistical considerations

28 Apr, 2023 | 12:47h | UTC

Extracorporeal cardiopulmonary resuscitation dissemination and integration with organ preservation in the USA: ethical and logistical considerations – Critical Care

Opinion | Precision palliative care as a pragmatic solution for a care delivery problem

26 Apr, 2023 | 14:19h | UTC

Precision Palliative Care as a Pragmatic Solution for a Care Delivery Problem – Journal of Clinical Oncology

Commentary from the author on Twitter (thread – click for more)

In the @JCO_ASCO‼️‼️, @ravi_b_parikh & I make the case for 🎯"Precision Palliative Care" 🎯as a pragmatic solution for a care delivery problem

A 🧵
Article https://t.co/1mYcaVIov4 pic.twitter.com/5Kj87rcuZK

— Ramy Sedhom, MD (@ramsedhom) April 22, 2023

Study shows approximately half of infectious diseases guideline authors have conflicts of interest with pharmaceutical companies

18 Apr, 2023 | 13:28h | UTC

Conflicts of Interest Among Infectious Diseases Clinical Practice Guideline Authors and the Pharmaceutical Industry – JAMA Network Open

Report | The implications of defining obesity as a disease

18 Apr, 2023 | 12:55h | UTC

The implications of defining obesity as a disease: a report from the Association for the Study of Obesity 2021 annual conference – eClinicalMedicine

Commentary on Twitter

The implications of defining #obesity as a disease: a report from the ASO 2021 annual conference

"the goal is common: to provide a healthcare system that supports and protects the patients…and policies that reduce stigma and promote health equity"https://t.co/Iftxra5i2g pic.twitter.com/8luPJchn3x

— eClinicalMedicine – The Lancet Discovery Science (@eClinicalMed) April 11, 2023

ChatGPT et al? Not so fast, say journal editors

11 Apr, 2023 | 14:36h | UTC

ChatGPT et al? Not So Fast, Say Journal Editors – TCTMD

Related:

AI-Generated Medical Advice—GPT and Beyond – JAMA (free for a limited period)

Chat GPT will change Medicine – Vinay Prasad’s Observations and Thoughts

The use of ChatGPT and other large language models in surgical science – BJS Open

ChatGPT vs. NCI: analyzing the quality of cancer information on myths and misconceptions

ChatGPT has many uses. Experts explore what this means for healthcare and medical research – The Conversation

Artificial Intelligence in Medicine & ChatGPT: De-Tether the Physician – Journal of Medical Systems (if the link is paywalled, try this one)

Can artificial intelligence help for scientific writing? – Critical Care

Artificial intelligence in academic writing: a paradigm-shifting technological advance

Performance of ChatGPT on USMLE: potential for AI-assisted medical education using large language models

Perspective | ChatGPT-assisted diagnosis: is the future suddenly here?

Perspective | Generating scholarly content with ChatGPT: ethical challenges for medical publishing

ChatGPT: Will It Transform the World of Health Care? – UCSF Department of Medicine

ChatGPT and the future of medical writing (ChatGPT itself wrote this paper)

ChatGPT: five priorities for research – Nature

The path forward for ChatGPT in academia – Lumo’s Newsletter

Nonhuman “Authors” and Implications for the Integrity of Scientific Publication and Medical Knowledge – JAMA

ChatGPT is fun, but not an author – Science

Tools such as ChatGPT threaten transparent science; here are our ground rules for their use – Nature

ChatGPT listed as author on research papers: many scientists disapprove – Nature

Abstracts written by ChatGPT fool scientists

Perspective | Gender dysphoria in young people is rising — and so is professional disagreement

28 Feb, 2023 | 13:55h | UTC

Gender dysphoria in young people is rising—and so is professional disagreement – The BMJ

News Release: Gender dysphoria is rising—and so is professional disagreement – BMJ Newsroom

Commentary on Twitter

More children and adolescents are identifying as transgender and are being offered medical treatment, especially in the US—but some providers and European authorities are urging caution because of a lack of strong evidence. @writingblock reports https://t.co/24aDMo7rb0

— The BMJ (@bmj_latest) February 26, 2023

Perspective | The inertia of clinical trials and unethical control arms in oncology

28 Feb, 2023 | 13:51h | UTC

The inertia of clinical trials and unethical control arms – Sensible Medicine

Cohort Study | Aggressive end-of-life care is still common among older adults with metastatic cancer in the US

27 Feb, 2023 | 13:11h | UTC

Summary: The study aimed to compare the markers of aggressive end-of-life (EOL) care between older adults with metastatic cancer who are nursing home (NH) residents and those who live in community settings. The study analyzed data from 146,329 patients who died from metastatic breast, colorectal, lung, pancreas, or prostate cancer between 2013 and 2017, and found that aggressive EOL care was more common among NH residents than community-dwelling residents (63.6% vs. 58.3%). More than one hospital admission in the last 30 days of life and death in the hospital were the key markers associated with a higher prevalence of aggressive EOL care. The authors suggest that interventions targeting these factors could improve the quality of end-of-life care.

Article: Incidence of Aggressive End-of-Life Care Among Older Adults With Metastatic Cancer Living in Nursing Homes and Community Settings – JAMA Network Open

Analysis | High drug prices are not justified by industry’s spending on research and development

21 Feb, 2023 | 11:41h | UTC

High drug prices are not justified by industry’s spending on research and development – The BMJ

News Release: Drug prices not justified by industry’s research and development spending – BMJ Newsroom

Commentary: Pharmaceutical companies can develop more innovative and affordable medicines by refocusing their spending but government intervention is needed – London School of Hygiene & Tropical Medicine

Commentary from the author on Twitter (thread – click for more)

New @bmj_latest paper📭

High drug prices do not seem justified by pharma industry’s R&D spending & new drugs' added benefits 💊💰
How can companies develop more innovative & affordable medicines?

Read the thread 🧵https://t.co/YYznD4Tvwq @ojwouters @ElsTorreele @martinmckee

— Aris Angelis (@Aris_Angelis) February 16, 2023

M-A | Financial toxicity among patients with breast cancer worldwide

17 Feb, 2023 | 13:20h | UTC

Financial Toxicity Among Patients With Breast Cancer Worldwide: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary: Breast Cancer Treatment Is Associated With Financial Toxicity Worldwide, Study Finds – AJMC

Financial Toxicity in Advanced and Metastatic Cancer: Overburdened and Underprepared – JCO Oncology Practice

The high price of anticancer drugs: origins, implications, barriers, solutions – Nature Reviews: Clinical Oncology

Unmet Need for Clinician Engagement Regarding Financial Toxicity After Diagnosis of Breast Cancer – Cancer

Financial toxicity: 1 in 3 cancer patients have to turn to friends or family to pay for care – STAT News

Not Just Nausea And Vomiting: Cancer Docs Now Worry About ‘Financial Toxicity’ – WBUR

Financial Toxicity and Cancer Treatment (PDQ®) – National Institute of Cancer

Commentary on Twitter

Financial toxicity for patients with breast cancer (pooled): 78% in LMICs and 35% in HICs; much higher than other health conditions, including other cancers. Policies to address this huge burden are critical to improve financial and health outcomes. https://t.co/eaB7nCvurU

— JAMA Network Open (@JAMANetworkOpen) February 9, 2023

Regulations on palliative sedation: an international survey across eight European countries

16 Feb, 2023 | 15:17h | UTC

Regulations on palliative sedation: an international survey across eight European countries – European Journal of Public Health

Developments under assisted dying legislation: the experience in Belgium and other countries

14 Feb, 2023 | 11:02h | UTC

Summary: The legalization of assisted dying (including euthanasia and physician-assisted suicide) remains a controversial issue as more countries consider such laws. A selective literature review was conducted to examine the developments globally, and the experience in Belgium was found to be instructive. Since legalization, the practice of assisted dying has increased gradually, accompanied by a growing acceptance among the public and physicians. Although fears have been largely alleviated, ongoing monitoring and research are necessary to address important concerns. Research in Belgium has not found evidence of harmful effects, but the implementation of assisted dying laws should always consider integration into the healthcare system, physician training, conscientious objection, availability of palliative care, public education, and monitoring systems. To ensure the quality of end-of-life care, it is advisable to set up monitoring and evaluation systems and carry out impartial studies. It is important to have high levels of openness and involvement with healthcare providers and the general public.

(By ChatGPT, reviewed and edited)

Article: Developments Under Assisted Dying Legislation: The Experience in Belgium and other countries – Deutsches Ärzteblatt international