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Bioethics

Navigating financial toxicity in patients with cancer: A multidisciplinary management approach.

26 May, 2022 | 10:57h | UTC

Navigating financial toxicity in patients with cancer: A multidisciplinary management approach – CA: A Cancer Journal for Clinicians

Related:

Financial Toxicity in Advanced and Metastatic Cancer: Overburdened and Underprepared – JCO Oncology Practice

The high price of anticancer drugs: origins, implications, barriers, solutions – Nature Reviews: Clinical Oncology

Unmet Need for Clinician Engagement Regarding Financial Toxicity After Diagnosis of Breast Cancer – Cancer

Financial toxicity: 1 in 3 cancer patients have to turn to friends or family to pay for care – STAT News 

Not Just Nausea And Vomiting: Cancer Docs Now Worry About ‘Financial Toxicity’ – WBUR 

Financial Toxicity and Cancer Treatment (PDQ®) – National Institute of Cancer

Financial Toxicity: Cancer Supportive Care Professionals Consider the Side Effects of Soaring Costs – ASCO Post

 


Viewpoint: The imperative for diversity and inclusion in clinical trials and health research participation.

23 May, 2022 | 00:49h | UTC

The Imperative for Diversity and Inclusion in Clinical Trials and Health Research Participation – JAMA

 


Results of two cases of pig-to-human kidney xenotransplantation.

19 May, 2022 | 11:11h | UTC

Results of Two Cases of Pig-to-Human Kidney Xenotransplantation – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 


ECRI and ISMP Public Statement | Medication errors are complex; criminal charges will not improve care.

10 May, 2022 | 11:29h | UTC

ECRI and ISMP PUBLIC STATEMENT | Medication Errors are Complex; Criminal Charges Will Not Improve Care – Institute for Safe Medication Practices

See also:

ISMP Speaks Out Against Criminalization of Medication Errors – Institute for Safe Medication Practices

The simple thing hospitals can do to prevent dangerous drug mistakes – CNN

 


WHO reveals shocking extent of exploitative formula milk marketing.

29 Apr, 2022 | 10:58h | UTC

News Release: WHO reveals shocking extent of exploitative formula milk marketing – World Health Organization

Report: Scope and impact of digital marketing strategies for promoting breastmilk substitutes – World Health Organization

Related: More than half of parents and pregnant women exposed to aggressive formula milk marketing – WHO, UNICEF – World Health Organization

 

Commentary on Twitter (thread – click for more)

 


Analysis | Presenting complaint: use of language that disempowers patients.

28 Apr, 2022 | 11:02h | UTC

Presenting complaint: use of language that disempowers patients – The BMJ

News Release: Language that belittles or blames patients is overdue for change – British Medical Journal

 


FDA warns of risks associated with non-invasive prenatal screening tests – inappropriate interpretation of results may lead to potentially improper medical decisions.

20 Apr, 2022 | 09:52h | UTC

FDA Warns of Risks Associated with Non-Invasive Prenatal Screening Tests – U.S. Food & Drug Administration

See also: Genetic Non-Invasive Prenatal Screening Tests May Have False Results: FDA Safety Communication – U.S. Food & Drug Administration

 


Evaluation of the causes of sex disparity in heart failure trials.

20 Apr, 2022 | 09:41h | UTC

Evaluation of the causes of sex disparity in heart failure trials – Heart

 

Commentary on Twitter

Images and article under a http://creativecommons.org/licenses/by-nc/4.0/ license

 


Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge (deliberately infecting individuals in a controlled environment) in young adults.

4 Apr, 2022 | 01:27h | UTC

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults – Nature Medicine

Commentaries:

Understanding COVID-19 through human challenge models – Nature Medicine

First human challenge study of Covid-19 yields valuable insights about how we get sick – CNN

First Human Challenge Trial Shows How COVID-19 Strikes – HealthDay

Related:

Scientists deliberately gave people COVID — here’s what they learnt.

[Preprint] Results from the first Covid-19 human challenge study (deliberately infecting individuals in a controlled environment).

Perspective | SARS-CoV-2 human challenge studies — establishing the model during an evolving pandemic.

World’s first coronavirus “Human Challenge” study receives ethics approval in the UK  (several texts on the subject)

Are SARS-CoV-2 Human Challenge Trials Ethical? – “A clinical trial is underway in the UK in which young, healthy participants are exposed deliberately to SARS-CoV-2 to assess the viral inoculum needed to produce an infection and to test vaccine efficacy”.

 

Commentary on Twitter

 


Prevalence of third-party tracking on medical journal websites.

23 Mar, 2022 | 09:56h | UTC

Prevalence of Third-party Tracking on Medical Journal Websites – JAMA Health Forum

 

Commentary on Twitter

 


Study shows whole-genome risk prediction of common diseases in human preimplantation embryos is feasible, leading to ethical concerns.

22 Mar, 2022 | 09:42h | UTC

Whole-genome risk prediction of common diseases in human preimplantation embryos – Nature Medicine

Invited Commentaries:

Polygenic embryo testing: understated ethics, unclear utility – Nature Medicine

The uncertain science of preimplantation and prenatal genetic testing – Nature Medicine

Commentary: As genetic testing of human embryos expand, researchers call for frank assessment of profound ethical implications – The Hastings Center

Related: Opinion | “The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice”.

 

Commentary on Twitter (thread – click for more)

 


Enabling patient choice: the “deciding not to decide” option for older adults facing dialysis decisions.

22 Mar, 2022 | 08:25h | UTC

Enabling Patient Choice: The “Deciding Not to Decide” Option for Older Adults Facing Dialysis Decisions – Journal of the American Society of Nephrology

Commentary: The “Deciding Not to Decide” Option Can Improve Older Adult Patient Care – Rutgers University-New Brunswick

 


Opinion: Open science, done wrong, will compound inequities.

15 Mar, 2022 | 08:14h | UTC

Open science, done wrong, will compound inequities – Nature

Related:

Open-access publishing fees deter researchers in the global south.

Impact factor abandoned by Dutch university in hiring and promotion decisions – “Faculty and staff members at Utrecht University will be evaluated by their commitment to open science”.

Open-access Science Funders Announce Price Transparency Rules for Publishers (several resources on the subject)

A new mandate highlights costs, benefits of making all scientific articles free to read – Science

A guide to Plan S: the open-access initiative shaking up science publishing – Nature

 


Bioethics | The rupture of anonymity for sperm donors—a tangled web of conflicting rights.

14 Mar, 2022 | 00:49h | UTC

The rupture of anonymity for sperm donors—a tangled web of conflicting rights – The BMJ

 

Commentary on Twitter

 


Misinformation: susceptibility, spread, and interventions to immunize the public.

11 Mar, 2022 | 10:03h | UTC

Misinformation: susceptibility, spread, and interventions to immunize the public – Nature Medicine

See also: An epidemic of uncertainty: rumors, conspiracy theories and vaccine hesitancy – Nature Medicine

 


Perspective: The time toxicity of cancer treatment.

10 Mar, 2022 | 10:15h | UTC

The Time Toxicity of Cancer Treatment – Journal of Clinical Oncology

 


Four reasons why too many informed consents to clinical research are invalid: a critical analysis of current practices.

9 Mar, 2022 | 08:45h | UTC

Four reasons why too many informed consents to clinical research are invalid: a critical analysis of current practices – BMJ Open

 


WHO/UNICEF: More than half of parents and pregnant women exposed to aggressive formula milk marketing.

23 Feb, 2022 | 10:42h | UTC

More than half of parents and pregnant women exposed to aggressive formula milk marketing – WHO, UNICEF – World Health Organization

Commentary: Aggressive’ marketing of formula milk flouts code, warns WHO as it urges curbs – The Guardian

 

Commentary on Twitter

 


Opinion | Controlling the control arm in metastatic castration-resistant prostate cancer trials: best standard of care or the minimum standard of care?

23 Feb, 2022 | 10:03h | UTC

Controlling the Control Arm in Metastatic Castration-Resistant Prostate Cancer Trials: Best Standard of Care or the Minimum Standard of Care? – Journal of Clinical Oncology

 


Perspective | How to banish manels and manferences from scientific meetings.

22 Feb, 2022 | 08:23h | UTC

How to banish manels and manferences from scientific meetings – Nature

 


Scientists deliberately gave people COVID — here’s what they learnt.

15 Feb, 2022 | 10:06h | UTC

Scientists deliberately gave people COVID — here’s what they learnt – Nature

Original Study: [Preprint] Results from the first Covid-19 human challenge study (deliberately infecting individuals in a controlled environment).

Related:

Perspective | SARS-CoV-2 human challenge studies — establishing the model during an evolving pandemic.

World’s first coronavirus “Human Challenge” study receives ethics approval in the UK  (several texts on the subject)

Are SARS-CoV-2 Human Challenge Trials Ethical? – “A clinical trial is underway in the UK in which young, healthy participants are exposed deliberately to SARS-CoV-2 to assess the viral inoculum needed to produce an infection and to test vaccine efficacy”.

 


Ending the evidence gap for pregnancy, HIV and co-infections: ethics guidance from the PHASES project.

15 Feb, 2022 | 08:35h | UTC

Ending the evidence gap for pregnancy, HIV and co-infections: ethics guidance from the PHASES project – Journal of the International AIDS Society

 


FIMS / EFSMA Joint position statement on the International Olympic Committee framework on fairness, inclusion and non-discrimination based on gender identity and sex variations.

13 Feb, 2022 | 22:17h | UTC

Joint position statement of the International Federation of Sports Medicine (FIMS) and European Federation of Sports Medicine Associations (EFSMA) on the IOC framework on fairness, inclusion and non-discrimination based on gender identity and sex variations – BMJ Open Sport & Exercise Medicine

Original Guidance: IOC Framework on fairness, inclusion and non-discrimination on the basis of gender identity and sex variations – International Olympic Committee

Commentary: International Olympic Committee transgender guidance criticised by medical experts – BBC

 

Commentary on Twitter

 


Experts question unusual authorization plan for Covid vaccine for kids under 5.

4 Feb, 2022 | 09:57h | UTC

Experts question unusual authorization plan for Covid vaccine for kids under 5 – STAT

Related:

Pfizer and BioNTech seeking emergency use authorization from FDA for Covid-19 vaccine for children younger than 5 – CNN

Pfizer asks FDA to allow COVID-19 vaccine for kids under 5 – Associated Press

Pfizer Asks FDA to Approve Its Vaccine for the Youngest Children – HealthDay

 


Viewpoint: social media and the transformation of the physician-patient relationship.

4 Feb, 2022 | 08:28h | UTC

Social Media and the Transformation of the Physician-Patient Relationship: Viewpoint – Journal of Medical Internet Research

 


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