General Gynecology
RCT | Mammography screening with AI reduces workload by 44.3% without loss in detection efficacy
4 Aug, 2023 | 12:13h | UTCArtificial intelligence-supported screen reading versus standard double reading in the Mammography Screening with Artificial Intelligence trial (MASAI): a clinical safety analysis of a randomised, controlled, non-inferiority, single-blinded, screening accuracy study – The Lancet Oncology (link to abstract – $ for full-text)
News Release: First randomized trial finds AI-supported mammography screening is safe and almost halves radiologist workload – Lancet
Commentaries:
Large Mammography Study Shows Significant Benefits with AI-Aided Screening – Diagnostic Imaging
Systematic Review | Moderate evidence supports interactive mobile phone interventions for contraception use enhancement
25 Jul, 2023 | 13:25h | UTCMobile phone‐based interventions for improving contraception use – Cochrane Library
FDA approves first nonprescription daily oral contraceptive
19 Jul, 2023 | 14:25h | UTCFDA Approves First Nonprescription Daily Oral Contraceptive – U.S. Food & Drug Administration
Cohort Study | Long-term use of menopausal hormone therapy linked to heightened dementia risk
11 Jul, 2023 | 14:04h | UTCMenopausal hormone therapy and dementia: nationwide, nested case-control study – The BMJ
Editorial: Menopausal hormone therapy and dementia – The BMJ
News Release: Menopausal hormone therapy linked to increased rate of dementia – BMJ Newsroom
Commentaries: Expert reaction to observational study on HRT and dementia – Science Media Centre
RCT | Effect of mifepristone vs. placebo for treatment of adenomyosis with pain symptoms
5 Jul, 2023 | 01:06h | UTCSee also: Visual Abstract
SR | Gonadotropin‐releasing hormone analogues for endometriosis
3 Jul, 2023 | 14:14h | UTCGonadotropin‐releasing hormone analogues for endometriosis – Cochrane Library
Summary: Gonadotrophin-releasing hormone analogues for pain associated with endometriosis – Cochrane Library
SR | Oral contraceptives containing drospirenone for premenstrual syndrome
3 Jul, 2023 | 14:13h | UTCOral contraceptives containing drospirenone for premenstrual syndrome – Cochrane Library
Summary: Birth control pills with drospirenone for treating premenstrual syndrome – Cochrane Library
RCT | Noninferior results with quick resumption of activity after pelvic organ prolapse surgery
30 Jun, 2023 | 14:38h | UTCStandard Restrictions vs Expedited Activity After Pelvic Organ Prolapse Surgery: A Randomized Clinical Trial – JAMA Surgery (link to abstract – $ for full-text)
See also: Visual Abstract
Commentary: No Need to Avoid Exercise After Prolapse Surgery, Study Finds – HealthDay
M-A | The effectiveness and safety of laparoscopic uterosacral ligament suspension
30 Jun, 2023 | 14:37h | UTC
FIGO staging of endometrial cancer: 2023
29 Jun, 2023 | 13:53h | UTCFIGO staging of endometrial cancer: 2023 – Gynecology & Obstetrics
Cohort Study | Increased depression risk observed in first two years of oral contraceptive use
23 Jun, 2023 | 13:19h | UTCNews Release: New study links contraceptive pills and depression – Uppsala University
Commentary: Depression Risk May Rise During First Two Years of Oral Contraceptive Use – Psychiatric News Alert
Commentary on Twitter
Population-based cohort study of oral #contraceptive use and risk of #depression suggests that the use of OCs, particularly during the first 2 years, increases the risk of depression.https://t.co/spWuqCMKfW@therese_johans #mentalhealth #epidemiology pic.twitter.com/xMO0yiqPvt
— Epidemiology & Psychiatric Sciences (@EpiPsychSci) June 19, 2023
SR | Effectiveness of anticholinergic drugs for treating people with overactive bladder syndrome
12 Jun, 2023 | 13:41h | UTC
Podcast | Ascend your understanding of pelvic inflammatory disease
6 Jun, 2023 | 14:23h | UTC#83: Ascend Your Understanding of Pelvic Inflammatory Disease (PID) – The Cribsiders
#ASCO23 – RCT | Simple hysterectomy shown non-inferior to radical hysterectomy in low-risk early-stage cervical cancer
5 Jun, 2023 | 13:43h | UTCCommentaries:
Cohort Study | Associations of menstrual cycle regularity and length with cardiovascular diseases
1 Jun, 2023 | 12:07h | UTCNews Release: Long or short menstrual cycles linked to higher risk of CVD including atrial fibrillation – American Heart Association
Review | Managing menopausal symptoms, fertility, and bone health in breast cancer women on endocrine therapy
30 May, 2023 | 11:40h | UTC
A pragmatic approach to the management of menopause
25 May, 2023 | 11:30h | UTCA pragmatic approach to the management of menopause – Canadian Medical Association Journal
News Release: Managing menopause: Hormone therapy is back – Canadian Medical Association Journal
RCT | Spironolactone enhances acne outcomes and offers a viable alternative to oral antibiotics
24 May, 2023 | 13:27h | UTCSummary: The SAFA (Spironolactone for Adult Female Acne) trial was a multicenter, phase 3, double-blind, randomized controlled trial in England and Wales and evaluated the efficacy of spironolactone for treating adult women with acne vulgaris. A total of 410 women, aged ≥18 years and suffering from facial acne for a minimum of six months, were randomly assigned to receive either 50 mg/day of spironolactone or a placebo, increasing to 100 mg/day until week 24.
The primary outcome was measured by the Acne-Specific Quality of Life (Acne-QoL) symptom subscale score at week 12 and 24. The trial demonstrated that spironolactone improved Acne-QoL scores more effectively than the placebo, particularly at week 24. Additionally, more participants in the spironolactone group reported acne improvement, and treatment success was significantly higher in this group at week 12. Mild side effects, notably headaches, were more common in the spironolactone group.
The findings from the SAFA trial highlight spironolactone’s effectiveness, safety, and tolerability in treating adult women with acne vulgaris, suggesting it is a viable alternative to long-term antibiotic treatments. Future research is proposed on higher initial dosages of spironolactone, and its effects on different subgroups like patients with different ages, body mass index, and ethnicity.
Editorial: What do we know about prescribing spironolactone for acne? – The BMJ
News Release: Non-antibiotic treatment for women with persistent acne shown to be effective – University of Southhampton
USPSTF Draft Statement recommends biennial screening mammography for women ages 40 to 74 years
22 May, 2023 | 13:56h | UTCBreast Cancer: Screening – U.S. Preventive Services Task Force
Critical perspectives on the statement:
Earlier screening for breast cancer: Benefits and harms – Lown Institute
Why more mammograms aren’t the solution to breast cancer – Vox
RCT | Neck–shoulder region training for chronic headache in women
15 May, 2023 | 12:59h | UTC
Commentary on Twitter
Neck-Shoulder Region Training for Chronic Headache in Women: A Randomized Controlled Trial
????
"The progressive exercise program almost halved headache frequency"https://t.co/HQN2yppF27 pic.twitter.com/3ZFltwJTWl
— Physio Meets Science (@PhysioMeScience) April 26, 2023
RCT | Transvenous occlusion of incompetent pelvic veins to treat chronic pelvic pain in women
15 May, 2023 | 12:54h | UTC
Single-arm study | Halting endocrine therapy for pregnancy not linked to increased breast cancer events vs. a control cohort
10 May, 2023 | 16:01h | UTCInterrupting Endocrine Therapy to Attempt Pregnancy after Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
In women with previous breast cancer who temporarily discontinued adjuvant endocrine therapy to attempt pregnancy, the frequency of breast cancer events was below the prespecified safety threshold and similar to that in controls (POSITIVE trial). https://t.co/zM3f4SbgjE
— NEJM (@NEJM) May 3, 2023
Cohort Study | Limited evidence linking COVID-19 vaccines to menstrual disturbance or postmenopausal bleeding
9 May, 2023 | 14:52h | UTCNews Release: New study finds no increased risk of menstrual changes after covid-19 vaccination – BMJ Newsroom
Commentary: Large study shows no changes to menstrual cycles after COVID vaccination – CIDRAP
Related:
Editorial: Menstruation and Covid-19 vaccination.
Commentary on Twitter
The findings of this new study do not provide substantial support for a causal association between SARS-CoV-2 vaccination and healthcare contacts related to menstrual or bleeding disordershttps://t.co/Tsw2hjIiIz
— The BMJ (@bmj_latest) May 4, 2023
Enhanced recovery after surgery (ERAS) society guidelines for gynecologic oncology: addressing implementation challenges
5 May, 2023 | 14:53h | UTC
RCT | Levonorgestrel IUS vs. hysteroscopic niche resection for postmenstrual spotting in cesarean scar
3 May, 2023 | 15:15h | UTC