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General Gynecology

SR | Oral contraceptives containing drospirenone for premenstrual syndrome

3 Jul, 2023 | 14:13h | UTC

Oral contraceptives containing drospirenone for premenstrual syndrome – Cochrane Library

Summary: Birth control pills with drospirenone for treating premenstrual syndrome – Cochrane Library

 


RCT | Noninferior results with quick resumption of activity after pelvic organ prolapse surgery

30 Jun, 2023 | 14:38h | UTC

Standard Restrictions vs Expedited Activity After Pelvic Organ Prolapse Surgery: A Randomized Clinical Trial – JAMA Surgery (link to abstract – $ for full-text)

See also: Visual Abstract

Commentary: No Need to Avoid Exercise After Prolapse Surgery, Study Finds – HealthDay

 


M-A | The effectiveness and safety of laparoscopic uterosacral ligament suspension

30 Jun, 2023 | 14:37h | UTC

The effectiveness and safety of laparoscopic uterosacral ligament suspension: a systematic review and meta-analysis – BJOG

 


FIGO staging of endometrial cancer: 2023

29 Jun, 2023 | 13:53h | UTC

FIGO staging of endometrial cancer: 2023 – Gynecology & Obstetrics

 


Cohort Study | Increased depression risk observed in first two years of oral contraceptive use

23 Jun, 2023 | 13:19h | UTC

Population-based cohort study of oral contraceptive use and risk of depression – Epidemiology and Psychiatric Sciences

News Release: New study links contraceptive pills and depression – Uppsala University

Commentary: Depression Risk May Rise During First Two Years of Oral Contraceptive Use – Psychiatric News Alert

 

Commentary on Twitter

 


SR | Effectiveness of anticholinergic drugs for treating people with overactive bladder syndrome

12 Jun, 2023 | 13:41h | UTC

Oral anticholinergic drugs versus placebo or no treatment for managing overactive bladder syndrome in adults – Cochrane Library

Summary: Effectiveness of anticholinergic drugs for treating people with overactive bladder syndrome – Cochrane Library

 


Podcast | Ascend your understanding of pelvic inflammatory disease

6 Jun, 2023 | 14:23h | UTC

#83: Ascend Your Understanding of Pelvic Inflammatory Disease (PID) – The Cribsiders

 


#ASCO23 – RCT | Simple hysterectomy shown non-inferior to radical hysterectomy in low-risk early-stage cervical cancer

5 Jun, 2023 | 13:43h | UTC

An international randomized phase III trial comparing radical hysterectomy and pelvic node dissection (RH) vs simple hysterectomy and pelvic node dissection (SH) in patients with low-risk early-stage cervical cancer (LRESCC):  A Gynecologic Cancer Intergroup study led by the Canadian Cancer Trials Group (CCTG CX.5-SHAPE). – American Society of Clinical Oncology (link to abstract – not published yet)

Commentaries:

SHAPE Trial: Radical Hysterectomy May Not Be Needed for Early-Stage, Low-Risk Cervical Cancer – ASCO Daily News

Simple Hysterectomy May Be a Safe Option for Patients With Early-Stage, Low-Risk Cervical Cancer – The ASCO Post

 


Cohort Study | Associations of menstrual cycle regularity and length with cardiovascular diseases

1 Jun, 2023 | 12:07h | UTC

Associations of Menstrual Cycle Regularity and Length With Cardiovascular Diseases: A Prospective Study From UK Biobank – Journal of the American Heart Association

News Release: Long or short menstrual cycles linked to higher risk of CVD including atrial fibrillation – American Heart Association

 


Review | Managing menopausal symptoms, fertility, and bone health in breast cancer women on endocrine therapy

30 May, 2023 | 11:40h | UTC

Advances in the Management of Menopausal Symptoms, Fertility Preservation, and Bone Health for Women With Breast Cancer on Endocrine Therapy – ASCO Educational Book

 


A pragmatic approach to the management of menopause

25 May, 2023 | 11:30h | UTC

A pragmatic approach to the management of menopause – Canadian Medical Association Journal

News Release: Managing menopause: Hormone therapy is back – Canadian Medical Association Journal

 


RCT | Spironolactone enhances acne outcomes and offers a viable alternative to oral antibiotics

24 May, 2023 | 13:27h | UTC

Summary: The SAFA (Spironolactone for Adult Female Acne) trial was a multicenter, phase 3, double-blind, randomized controlled trial in England and Wales and evaluated the efficacy of spironolactone for treating adult women with acne vulgaris. A total of 410 women, aged ≥18 years and suffering from facial acne for a minimum of six months, were randomly assigned to receive either 50 mg/day of spironolactone or a placebo, increasing to 100 mg/day until week 24.

The primary outcome was measured by the Acne-Specific Quality of Life (Acne-QoL) symptom subscale score at week 12 and 24. The trial demonstrated that spironolactone improved Acne-QoL scores more effectively than the placebo, particularly at week 24. Additionally, more participants in the spironolactone group reported acne improvement, and treatment success was significantly higher in this group at week 12. Mild side effects, notably headaches, were more common in the spironolactone group.

The findings from the SAFA trial highlight spironolactone’s effectiveness, safety, and tolerability in treating adult women with acne vulgaris, suggesting it is a viable alternative to long-term antibiotic treatments. Future research is proposed on higher initial dosages of spironolactone, and its effects on different subgroups like patients with different ages, body mass index, and ethnicity.

Article: Effectiveness of spironolactone for women with acne vulgaris (SAFA) in England and Wales: pragmatic, multicentre, phase 3, double blind, randomised controlled trial – The BMJ

Editorial: What do we know about prescribing spironolactone for acne? – The BMJ

News Release: Non-antibiotic treatment for women with persistent acne shown to be effective – University of Southhampton

 


USPSTF Draft Statement recommends biennial screening mammography for women ages 40 to 74 years

22 May, 2023 | 13:56h | UTC

Breast Cancer: Screening – U.S. Preventive Services Task Force

Critical perspectives on the statement:

Earlier screening for breast cancer: Benefits and harms – Lown Institute

Video: Mammography – Does it save lives? | The USPSTF is incorrect | I review ALL the data – By Dr. Vinay Prasad

Why more mammograms aren’t the solution to breast cancer – Vox

 


RCT | Neck–shoulder region training for chronic headache in women

15 May, 2023 | 12:59h | UTC

Neck–Shoulder Region Training for Chronic Headache in Women: A Randomized Controlled Trial – Clinical Rehabilitation

 

Commentary on Twitter

 


RCT | Transvenous occlusion of incompetent pelvic veins to treat chronic pelvic pain in women

15 May, 2023 | 12:54h | UTC

Transvenous occlusion of incompetent pelvic veins to treat chronic pelvic pain in women: A randomised controlled trial – BJOG

 


Single-arm study | Halting endocrine therapy for pregnancy not linked to increased breast cancer events vs. a control cohort

10 May, 2023 | 16:01h | UTC

Interrupting Endocrine Therapy to Attempt Pregnancy after Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Temporary Interruption of Adjuvant Endocrine Treatment to Attempt Pregnancy Does Not Increase Short-Term Risk for Worsening Breast Cancer Outcomes – ESMO

 

Commentary on Twitter

 


Cohort Study | Limited evidence linking COVID-19 vaccines to menstrual disturbance or postmenopausal bleeding

9 May, 2023 | 14:52h | UTC

Association between SARS-CoV-2 vaccination and healthcare contacts for menstrual disturbance and bleeding in women before and after menopause: nationwide, register based cohort study – The BMJ

News Release: New study finds no increased risk of menstrual changes after covid-19 vaccination – BMJ Newsroom

Commentary: Large study shows no changes to menstrual cycles after COVID vaccination – CIDRAP

Related:

A prospective study of the association between SARS-CoV-2 infection and COVID-19 vaccination with changes in usual menstrual cycle characteristics.

Editorial: Menstruation and Covid-19 vaccination.

 

Commentary on Twitter

 


Enhanced recovery after surgery (ERAS) society guidelines for gynecologic oncology: addressing implementation challenges

5 May, 2023 | 14:53h | UTC

Enhanced recovery after surgery (ERAS®) society guidelines for gynecologic oncology: Addressing implementation challenges – 2023 update – Gynecologic Oncology

 


RCT | Levonorgestrel IUS vs. hysteroscopic niche resection for postmenstrual spotting in cesarean scar

3 May, 2023 | 15:15h | UTC

Comparing levonorgestrel intrauterine system with hysteroscopic niche resection in women with postmenstrual spotting related to a niche in the uterine cesarean scar: a randomized, open-label, controlled trial – American Journal of Obstetrics & Gynecology

 


Cohort Study | Long-term health consequences after ovarian removal at benign hysterectomy

3 May, 2023 | 14:58h | UTC

Long-Term Health Consequences After Ovarian Removal at Benign Hysterectomy: A Nationwide Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Risks of removing ovaries at benign hysterectomy may outweigh the benefits for women at low risk for ovarian cancer – American College of Physicians

 


AUA/SUFU Guideline | Updates to surgical treatment of female stress urinary incontinence

2 May, 2023 | 13:43h | UTC

Updates to Surgical Treatment of Female Stress Urinary Incontinence (SUI): AUA/SUFU Guideline (2023) – The Journal of Urology

 


SR | Cranberries can prevent recurrent urinary tract infections in selected patients

25 Apr, 2023 | 14:41h | UTC

Cranberries for preventing urinary tract infections – Cochrane Library

Summary: Cranberries for preventing urinary tract infections – Cochrane Library

Commentaries:

Cranberry juice can prevent recurrent UTIs, but only for some people – The Conversation

Review confirms that cranberry products help prevent urinary tract infections – News Medical

 


Study suggests that routine axillary scanning in diagnostic breast ultrasound has limited impact on cancer detection

19 Apr, 2023 | 13:06h | UTC

To scan or not to scan: effect of scanning the axilla of all patients undergoing diagnostic breast ultrasound – Clinical Imaging (link to abstract – $ for full-text)

Commentary: Is scanning the axilla during diagnostic breast ultrasound necessary? – Health Imaging

 


M-A | Self-sampling strategies in populations at risk of Chlamydia trachomatis and Neisseria gonorrhoeae

18 Apr, 2023 | 13:09h | UTC

Self-sampling strategies (with/without digital innovations) in populations at risk of Chlamydia trachomatis and Neisseria gonorrhoeae: a systematic review and meta-analyses – Sexually Transmitted Infections

 

Commentary on Twitter

 


RCT | Safety of Fezolinetant for vasomotor symptoms associated with menopause

17 Apr, 2023 | 12:54h | UTC

Safety of Fezolinetant for Vasomotor Symptoms Associated With Menopause: A Randomized Controlled Trial – Obstetrics and Gynecology

Related:

RCT | Fezolinetant for treatment of moderate-to-severe vasomotor symptoms associated with menopause

RCT | Efficacy of Fezolinetant in moderate-to-severe vasomotor symptoms associated with menopause

 


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