Open access
Open access
Powered by Google Translator Translator

Oncology – Bone and Sarcomas

Consensus Paper | Ten recommendations for sarcoma surgery

14 Jul, 2023 | 12:49h | UTC

Ten recommendations for sarcoma surgery: consensus of the surgical societies based on the German S3 guideline “Adult Soft Tissue Sarcomas” – Langenbeck’s Archives of Surgery

 


RCT | Ganitumab added to chemotherapy did not improve outcomes in patients with metastatic Ewing sarcoma

30 Mar, 2023 | 14:16h | UTC

Randomized Phase III Trial of Ganitumab With Interval-Compressed Chemotherapy for Patients With Newly Diagnosed Metastatic Ewing Sarcoma: A Report From the Children’s Oncology Group – Journal of Clinical Oncology (link to abstract – $ for full-text)

Commentary: Ganitumab Provides No Benefit in Metastatic Ewing Sarcoma – Cancer Therapy Advisor

 


RCT | Nirogacestat for desmoid tumors

15 Mar, 2023 | 14:57h | UTC

Nirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Nirogacestat Improves Outcomes for Patients With Desmoid Tumors – Memorial Sloan Kettering Cancer Center

 

Commentary on Twitter

 


Consensus Recommendations | Spinal tumors

9 Mar, 2023 | 14:15h | UTC

Spinal tumours: recommendations of the Polish Society of Spine Surgery, the Polish Society of Oncology, the Polish Society of Neurosurgeons, the Polish Society of Oncologic Surgery, the Polish Society of Oncologic Radiotherapy, and the Polish Society of Orthopaedics and Traumatology – European Spine Journal

 


Review | Morbidity and mortality after surgery for retroperitoneal sarcoma

28 Feb, 2023 | 13:35h | UTC

Morbidity and Mortality after Surgery for Retroperitoneal Sarcoma – Current Oncology

 


German Guidelines on Sarcoma of the Uterus.

6 Dec, 2022 | 13:50h | UTC

Sarcoma of the Uterus. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/074, April 2021) – Geburtshilfe und Frauenheilkunde 


Single-arm P2 study | Hypofractionated, 3-week, preoperative radiotherapy for patients with soft tissue sarcomas.

9 Nov, 2022 | 12:24h | UTC

Hypofractionated, 3-week, preoperative radiotherapy for patients with soft tissue sarcomas (HYPORT-STS): a single-centre, open-label, single-arm, phase 2 trial – The Lancet Oncology (link to abstract – $ for full-text)

News Release: Shorter course of radiation therapy yields comparable results for patients with non-metastatic soft tissue sarcoma – The University of Texas MD Anderson Cancer Center

 


RCT | Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma.

9 Nov, 2022 | 12:12h | UTC

Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma (EE2012): an open-label, randomised, phase 3 trial – The Lancet (link to abstract – $ for full-text)

 


SR | Efficacy and safety of stereotactic body radiotherapy for painful bone metastases.

8 Nov, 2022 | 12:00h | UTC

Efficacy and safety of stereotactic body radiotherapy for painful bone metastases: Evidence from randomized controlled trials – Frontiers in Oncology

 


Single-arm phase 2 study | Activity of Cabazitaxel in metastatic or inoperable locally advanced dedifferentiated liposarcoma.

22 Aug, 2022 | 11:53h | UTC

Activity of Cabazitaxel in Metastatic or Inoperable Locally Advanced Dedifferentiated Liposarcoma: A Phase 2 Study of the EORTC Soft Tissue and Bone Sarcoma Group (STBSG) – JAMA Oncology (free for a limited period)

Invited Commentary: Optimizing Histology-Specific Clinical Trials in Soft-Tissue Sarcoma—Are We There Yet? – JAMA Oncology (free for a limited period)

 


Single-center phase 2 trial | Durvalumab plus tremelimumab in advanced or metastatic soft tissue and bone sarcomas.

11 Aug, 2022 | 11:52h | UTC

Durvalumab plus tremelimumab in advanced or metastatic soft tissue and bone sarcomas: a single-centre phase 2 trial – The Lancet Oncology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


RCT | Doxorubicin alone vs. doxorubicin with trabectedin followed by trabectedin alone as first-line therapy for metastatic or unresectable leiomyosarcoma.

20 Jul, 2022 | 11:36h | UTC

Doxorubicin alone versus doxorubicin with trabectedin followed by trabectedin alone as first-line therapy for metastatic or unresectable leiomyosarcoma (LMS-04): a randomised, multicentre, open-label phase 3 trial – The Lancet Oncology (link to abstract – $ for full-text)

 


RCT: Efficacy and safety of TRC105 plus pazopanib vs. pazopanib alone for treatment of patients with advanced angiosarcoma.

27 May, 2022 | 11:15h | UTC

Efficacy and Safety of TRC105 Plus Pazopanib vs Pazopanib Alone for Treatment of Patients With Advanced Angiosarcoma: A Randomized Clinical Trial – JAMA Oncology

Commentaries:

Addition of Carotuximab to Pazopanib in Advanced Angiosarcoma – The ASCO Post

Carotuximab addition to pazopanib does not improve survival in advanced angiosarcoma patients – Physician’s Weekly

 

Commentaries on Twitter

 


RCT: Selinexor in advanced, metastatic dedifferentiated liposarcoma.

12 Apr, 2022 | 08:24h | UTC

Selinexor in Advanced, Metastatic Dedifferentiated Liposarcoma: A Multinational, Randomized, Double-Blind, Placebo-Controlled Trial – Journal of Clinical Oncology

 


Guidelines for diagnosing incidental solitary bone lesions on CT and MRI in adults: bone reporting and data system (Bone-RADS).

4 Apr, 2022 | 00:45h | UTC

Society of Skeletal Radiology– white paper. Guidelines for the diagnostic management of incidental solitary bone lesions on CT and MRI in adults: bone reporting and data system (Bone-RADS) – Skeletal Radiology

 

Commentary on Twitter (article and images under a http://creativecommons.org/licenses/by-nc/4.0/)

 


Educational Review: Multiparametric MRI evaluation of bone sarcomas in children.

3 Mar, 2022 | 07:54h | UTC

Multiparametric MRI evaluation of bone sarcomas in children – Insights into Imaging

 


RCT: Prolonging prophylactic intravenous antibiotic regimens not beneficial after endoprosthetic reconstruction for lower extremity bone tumors.

19 Jan, 2022 | 08:37h | UTC

Comparison of Prophylactic Intravenous Antibiotic Regimens After Endoprosthetic Reconstruction for Lower Extremity Bone Tumors: A Randomized Clinical Trial – JAMA Oncology

Commentary: No Benefit Seen With Longer Antibiotic Course After Surgery for Bone Tumors – Cancer Therapy Advisor

 


Bone sarcomas: ESMO–EURACAN–GENTURIS–ERNPaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up.

1 Oct, 2021 | 09:57h | UTC

Bone sarcomas: ESMO–EURACAN–GENTURIS–ERNPaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up – Annals of Oncology

 


ASTRO Guideline: Radiation therapy for treatment of soft tissue sarcoma in adults.

29 Jul, 2021 | 10:54h | UTC

Radiation Therapy for Treatment of Soft Tissue Sarcoma in Adults: Executive Summary of an ASTRO Clinical Practice Guideline – Practical Radiation Oncology

News release: Astro Issues Clinical Guideline on Radiation Therapy for Soft Tissue Sarcoma in Adults

 


ESMO Guidelines: Soft tissue and visceral sarcomas.

29 Jul, 2021 | 10:53h | UTC

Soft tissue and visceral sarcomas: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up – Annals of Oncology

 


Meta-analysis: Bisphosphonates or RANK‐ligand‐inhibitors for men with prostate cancer and bone metastases

20 Jan, 2021 | 01:09h | UTC

Bisphosphonates or RANK‐ligand‐inhibitors for men with prostate cancer and bone metastases: a network meta‐analysis – Cochrane Library

 


Stay Updated in Your Specialty

Telegram Channels
Free

WhatsApp alerts 10-day free trial

No spam, just news.