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Critical Care

Position Paper: Management of drug-induced liver injury

25 Feb, 2021 | 08:27h | UTC

Drug-induced liver injury: A management position paper from the Latin American Association for Study of the liver – Annals of Hepatology

 


ICU-based renal replacement therapy

25 Feb, 2021 | 08:23h | UTC

ICU-Based Renal Replacement Therapy – Critical Care Medicine

 

Commentary on Twitter

 


Sepsis treatment: Another trial shows no benefit from the combination of Vitamin C, Thiamine, and Hydrocortisone

24 Feb, 2021 | 02:25h | UTC

Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Hydrocortisone, Vitamin C, and Thiamine for Treatment of Sepsis: Making Evidence Matter

Related: The VITAMINS Randomized Clinical Trial: Vitamin C, Hydrocortisone, and Thiamine Not beneficial for Patients with Sepsis (study and commentaries)

 

Commentary on Twitter

 


How the COVID-19 pandemic will change the future of critical care

24 Feb, 2021 | 02:49h | UTC

How the COVID-19 pandemic will change the future of critical care – Intensive Care Medicine

 

Commentary on Twitter

 


M-A: The diagnostic accuracy of noninvasive methods to measure the intracranial pressure

23 Feb, 2021 | 01:14h | UTC

The Diagnostic Accuracy of Noninvasive Methods to Measure the Intracranial Pressure: A Systematic Review and Meta-analysis – Anesthesia & Analgesia

 


FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias

23 Feb, 2021 | 02:03h | UTC

FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT

FDA Safety Alert: Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration

Related: “Racial Bias in Pulse Oximetry Measurement”. In two large cohorts, Black patients had nearly three times the frequency of occult hypoxemia that was not detected by pulse oximetry as White patients – New England Journal of Medicine (study and commentaries)

 


Editorial: Prophylactic anticoagulation for patients in hospital with covid-19

23 Feb, 2021 | 01:59h | UTC

Prophylactic anticoagulation for patients in hospital with covid-19 – The BMJ

Related: Full-dose Heparin best for moderate COVID-19 regardless of D-dimer — Data released from ACTIV-4a, ATTACC, and REMAP-CAP trials AND Cohort study: Early initiation of prophylactic anticoagulation linked to reduced mortality in patients admitted to hospital with Covid-19

 


Intensive care management of patients with COVID-19: a practical approach

21 Feb, 2021 | 22:34h | UTC

Intensive care management of patients with COVID-19: a practical approach – Intensive Care Management

Related Guideline: Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update AND Infographic

 


SOFA score is not accurate enough for mortality prediction in severely ill patients with COVID-19 pneumonia

19 Feb, 2021 | 02:44h | UTC

Determining the Probable Mortality of Patients With COVID-19 Pneumonia Requiring Mechanical Ventilation – JAMA

 

Commentary on Twitter

 


Review: Oxygen administration for patients with ARDS

19 Feb, 2021 | 02:24h | UTC

Oxygen administration for patients with ARDS – Journal of Intensive Care

 


RCT: Vitamin D3 does not improve outcomes in hospitalized patients with moderate to severe COVID-19

18 Feb, 2021 | 03:20h | UTC

Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial – JAMA

Editorial: Vitamin D3 to Treat COVID-19: Different Disease, Same Answer

 

 


Video: Emergency intubation in Covid-19

18 Feb, 2021 | 03:16h | UTC

Emergency Intubation in Covid-19 – New England Journal of Medicine

 


M-A: The effect of convalescent plasma therapy on COVID-19 patient mortality

18 Feb, 2021 | 03:07h | UTC

The Effect of Convalescent Plasma Therapy on COVID-19 Patient Mortality: Systematic Review and Meta-analysis – Mayo Clinic Proceedings

Related study (not published yet) with conflicting results: RECOVERY trial: No Benefit from convalescent plasma in hospitalized patients with Covid-19 (news release and commentary)

 


Patient characteristics and clinical outcomes of Type 1 vs. Type 2 myocardial infarction

18 Feb, 2021 | 02:54h | UTC

Patient Characteristics and Clinical Outcomes of Type 1 Versus Type 2 Myocardial Infarction – Journal of the American Academy of Cardiology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Short review: Acute CV complications of hematopoietic stem cell transplantation

18 Feb, 2021 | 02:40h | UTC

Acute CV Complications of Hematopoietic Stem Cell Transplantation – American College of Cardiology

 


Ocular MRI findings in patients with severe COVID-19

17 Feb, 2021 | 01:42h | UTC

Ocular MRI Findings in Patients with Severe COVID-19: A Retrospective Multicenter Observational Study – Radiology

Commentaries: New COVID-19 side effect: MRI links severe infection to dangerous eye problems – Health Imaging AND MRI illuminates COVID-19’s negative impact on the eyes – AuntMinnie AND Windows of Infection: MRI Reveals COVID-19-Linked Eye Abnormalities – Diagnostic Imaging

 


Cardiac arrest in COVID-19: characteristics and outcomes of in- and out-of-hospital cardiac arrest

17 Feb, 2021 | 01:32h | UTC

Cardiac arrest in COVID-19: characteristics and outcomes of in- and out-of-hospital cardiac arrest. A report from the Swedish Registry for Cardiopulmonary Resuscitation – European Heart Journal

Commentary: People infected with COVID-19 have a higher risk of dying after a cardiac arrest – European Society of Cardiology

 

Commentary on Twitter

 


Incidence rate and clinical impacts of arrhythmia following COVID-19: a systematic review and meta-analysis of 17,435 patients

17 Feb, 2021 | 01:31h | UTC

Incidence rate and clinical impacts of arrhythmia following COVID-19: a systematic review and meta-analysis of 17,435 patients – Critical Care

 


Study: Obesity and risk of catheter-related infections in the ICU

16 Feb, 2021 | 01:46h | UTC

Obesity and risk of catheter-related infections in the ICU. A post hoc analysis of four large randomized controlled trials – Intensive Care Medicine

 

Commentary on Twitter

 


Potential health and economic impacts of dexamethasone treatment for patients with COVID-19

16 Feb, 2021 | 02:10h | UTC

Potential health and economic impacts of dexamethasone treatment for patients with COVID-19 – Nature Communications

 

Commentary on Twitter

 


Opinion: RECOVERY confirms benefit of tocilizumab combined with dexamethasone

16 Feb, 2021 | 02:09h | UTC

PulmCrit – RECOVERY confirms benefit of toci combined with dexamethasone

Original study: RCT: Tocilizumab reduces deaths in patients hospitalized with COVID-19 (study and commentaries)

 


Consensus guidelines on perioperative management of suspected malignant hyperthermia or susceptible patients

15 Feb, 2021 | 00:56h | UTC

Consensus guidelines on perioperative management of malignant hyperthermia suspected or susceptible patients from the European Malignant Hyperthermia Group – British Journal of Anaesthesia

 


Randomized trial: Procalcitonin to reduce long-term infection-associated adverse events in sepsis

15 Feb, 2021 | 00:43h | UTC

Procalcitonin to Reduce Long-Term Infection-associated Adverse Events in Sepsis. A Randomized Trial – American Journal of Respiratory and Critical Care Medicine

 


Cohort study: Early initiation of prophylactic anticoagulation linked to reduced mortality in patients admitted to hospital with Covid-19

15 Feb, 2021 | 01:18h | UTC

Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study – The BMJ

Commentaries: Preventive blood thinning drugs could reduce COVID hospital deaths – London School of Hygiene & Tropical Medicine AND Preventive blood thinning drugs linked to reduced risk of death in COVID-19 patients – The BMJ AND Expert reaction to a study looking at prophylactic anticoagulants as a treatment for hospitalised patients with COVID-19 – Science Media Centre AND

 

Commentary on Twitter

 


Reports of anaphylaxis after receipt of mRNA COVID-19 vaccines in the US

15 Feb, 2021 | 01:13h | UTC

Reports of Anaphylaxis After Receipt of mRNA COVID-19 Vaccines in the US—December 14, 2020-January 18, 2021 – JAMA

Author interview: COVID-19 Vaccine Safety–Anaphylaxis and Allergic Reactions – JAMA

 

Commentary on Twitter

 


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