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Critical Care

AHA/ASA Guideline for the management of patients with aneurysmal subarachnoid hemorrhage

29 May, 2023 | 11:16h | UTC

2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage: A Guideline From the American Heart Association/American Stroke Association – Stroke

Top Things to Know: 2023 Aneurysmal Subarachnoid Hemorrhage Guideline – American Heart Association

 

Commentary on Twitter

 

RCT | Communication-priming intervention boosts goals-of-care discussions for seriously ill patients

29 May, 2023 | 11:12h | UTC

Intervention to Promote Communication About Goals of Care for Hospitalized Patients With Serious Illness: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Conversations on Goals of Care With Hospitalized, Seriously Ill Patients – JAMA (free for a limited period)

See also: Visual Abstract

Commentary: Some Surrogate Endpoints Are Fine – By Dr John Mandrola

 

M-A | Hydrocortisone shows no significant impact on 90-day mortality in septic shock patients

29 May, 2023 | 11:06h | UTC

Patient-Level Meta-Analysis of Low-Dose Hydrocortisone in Adults with Septic Shock – NEJM Evidence

News Release: Study examines the role of hydrocortisone in the management of adult patients with septic shock – University of California San Francisco Medical Center/News Medical

 

Consensus Paper | Cardiac arrest in the perioperative period

29 May, 2023 | 11:04h | UTC

Cardiac arrest in the perioperative period: a consensus guideline for identification, treatment, and prevention from the European Society of Anaesthesiology and Intensive Care and the European Society for Trauma and Emergency Surgery – European Journal of Anaesthesiology

 

Guideline | Investigation and management of acute transfusion reactions

29 May, 2023 | 11:02h | UTC

Guideline on the investigation and management of acute transfusion reactions – British Journal of Haematology

 

ISPD Catheter-related infection recommendations

29 May, 2023 | 11:00h | UTC

ISPD Catheter-related Infection Recommendations: 2023 Update – Peritoneal Dialysis International

 

Guideline | Targeted temperature management in intracerebral, subarachnoid hemorrhage and acute ischemic stroke

29 May, 2023 | 10:48h | UTC

Targeted temperature management in patients with intracerebral haemorrhage, subarachnoid haemorrhage, or acute ischaemic stroke: updated consensus guideline recommendations by the Neuroprotective Therapy Consensus Review (NTCR) group – British Journal of Anaesthesia

 

Consensus Statement | Rationale and clinical application of antimicrobial stewardship principles in the intensive care unit

24 May, 2023 | 13:15h | UTC

Rationale and clinical application of antimicrobial stewardship principles in the intensive care unit: a multidisciplinary statement – Journal of Anesthesia, Analgesia and Critical Care

 

M-A | Optimizing enteral nutrition delivery by implementing volume-based feeding protocol for critically ill patients

24 May, 2023 | 13:13h | UTC

Optimizing enteral nutrition delivery by implementing volume-based feeding protocol for critically ill patients: an updated meta-analysis and systematic review – Critical Care

 

Guideline | Assessment and early management of head injury

23 May, 2023 | 13:11h | UTC

Head injury: assessment and early management – NICE

Commentary: NICE head injury guidelines 2023: Now who do we scan? – St Emilyn’s

 

Review | Microcirculatory dysfunction in cardiogenic shock

23 May, 2023 | 12:50h | UTC

Microcirculatory dysfunction in cardiogenic shock – Annals of Intensive Care

 

Ventilator associated tracheobronchitis and pneumonia: one infection with two faces

23 May, 2023 | 12:49h | UTC

Ventilator associated tracheobronchitis and pneumonia: one infection with two faces – Intensive Care Medicine

 

Review | The esophageal balloon for respiratory monitoring in ventilated patients

23 May, 2023 | 12:40h | UTC

The oesophageal balloon for respiratory monitoring in ventilated patients: updated clinical review and practical aspects – European Respiratory Review

 

Editorial | Selective digestive decontamination – Pro

22 May, 2023 | 13:34h | UTC

Selective digestive decontamination – Pro – Intensive Care Medicine (free for a limited period)

 

Commentary on Twitter

 

Practice Guidance | Differential diagnosis of suspected COPD exacerbations in the acute care setting

15 May, 2023 | 13:26h | UTC

Differential Diagnosis of Suspected Chronic Obstructive Pulmonary Disease Exacerbations in the Acute Care Setting: Best Practice – American Journal of Respiratory and Critical Care Medicine

 

Commentary on Twitter

 

RCT | Prophylactic antibiotics show no statistically significant survival improvement in severe alcohol-related hepatitis

15 May, 2023 | 13:21h | UTC

Summary: This multicenter, randomized, double-blind clinical trial aimed to determine the efficacy of amoxicillin-clavulanate combined with prednisolone compared to placebo combined with prednisolone on mortality in patients hospitalized with severe alcohol-related hepatitis. The study involved 284 patients from 25 centers in France and Belgium with biopsy-proven severe alcohol-related hepatitis, who were followed up for 180 days.

The primary outcome was all-cause mortality at 60 days, while secondary outcomes included mortality at 90 and 180 days, infection rates, hepatorenal syndrome, and changes in Model for End-stage Liver Disease (MELD) and Lille scores. The results showed no statistically significant difference in 60-day mortality between the two groups, with 17.3% in the amoxicillin-clavulanate group and 21.3% in the placebo group. However, infection rates at 60 days were significantly lower in the amoxicillin-clavulanate group compared to the placebo group.

It is worth noting that the study may have been underpowered, as the absolute risk difference of 4% did not achieve statistical significance. In conclusion, the combination of amoxicillin-clavulanate and prednisolone did not show a statistically significant improvement in 2-month survival in patients hospitalized with severe alcohol-related hepatitis compared to prednisolone alone. These findings do not support the use of prophylactic antibiotics to improve survival in this patient population, but the potential underpowered nature of the study should be considered.

Article: Effect of Prophylactic Antibiotics on Mortality in Severe Alcohol-Related Hepatitis: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Therapeutic plasma exchange: Core curriculum 2023

15 May, 2023 | 13:14h | UTC

Therapeutic Plasma Exchange: Core Curriculum 2023 – American Journal of Kidney Diseases

 

Commentary on Twitter

 

Review | Intensive care unit–acquired weakness in patients with acute kidney injury

15 May, 2023 | 13:12h | UTC

Intensive Care Unit–Acquired Weakness in Patients With Acute Kidney Injury: A Contemporary Review – American Journal of Kidney Diseases

 

Commentary on Twitter

 

Brief Review | Coagulation support during perioperative bleeding management

15 May, 2023 | 13:01h | UTC

Coagulation support during perioperative bleeding management – Intensive Care Medicine

 

Commentary on Twitter

 

Review | Awake prone positioning in acute hypoxemic respiratory failure

15 May, 2023 | 12:56h | UTC

Awake prone positioning in acute hypoxaemic respiratory failure – European Respiratory Review

 

M-A | Effectiveness of diaphragmatic ultrasound as a predictor of successful weaning from mechanical ventilation

15 May, 2023 | 12:46h | UTC

Effectiveness of diaphragmatic ultrasound as a predictor of successful weaning from mechanical ventilation: a systematic review and meta-analysis – Critical Care

M-A | Endovascular therapy for stroke presenting beyond 24 hours

12 May, 2023 | 13:44h | UTC

Endovascular Therapy for Stroke Presenting Beyond 24 Hours: A Systematic Review and Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 

Review | Progress in the treatment of acute pulmonary embolism and chronic thrombo-embolic pulmonary hypertension/disease

12 May, 2023 | 13:24h | UTC

Progress in the treatment of acute pulmonary embolism and chronic thrombo-embolic pulmonary hypertension/disease – European Heart Journal Supplements

See all articles in the series here

 

Review | Takotsubo syndrome: more frequent in women, more dangerous in men

12 May, 2023 | 13:21h | UTC

Takotsubo syndrome: more frequent in women, more dangerous in men – European Heart Journal Supplements

See all articles in the series here

A review of bicarbonate use in common clinical scenarios

11 May, 2023 | 12:17h | UTC

A Review of Bicarbonate Use in Common Clinical Scenarios – The Journal of Emergency Medicine

 

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