Transplantation – Lung
Extracorporeal CPR dissemination and integration with organ preservation in the USA: ethical and logistical considerations
28 Apr, 2023 | 12:47h | UTC
Cold static preservation at 10°C shows promising results for safely extending lung transplantation timeframes
24 Apr, 2023 | 13:38h | UTCExtension of Cold Static Donor Lung Preservation at 10°C – NEJM Evidence
Commentary on Twitter
Donor lungs for transplantation are stored on ice and transplanted as rapidly as possible. In an advance that may ease transplant logistics, Ali et al. now report that prolonged storage of donor lungs at 10°C may lead to equivalent outcomes.
Read the Original Article:
— NEJM Evidence (@NEJMEvidence) April 22, 2023
Expanding Organ Usage: UK study finds organs from patients with a primary brain tumor are a viable option
27 Mar, 2023 | 13:27h | UTCSummary: A national cohort study in the UK investigated the risk of cancer transmission from deceased donors with primary brain tumors to organ recipients. The study found no cases of brain tumor transmission among 778 transplants from 282 donors with primary brain tumors, including 262 from donors with high-grade tumors. Organ transplant survival was equivalent to that in matched controls, and some organs from donors with high-grade tumors were less likely to be transplanted.
The results suggest that the risk of cancer transmission in transplants from deceased donors with primary brain tumors is lower than previously thought. Furthermore, the study indicated that donors with brain tumors provided good-quality organs with favorable risk markers and excellent transplant outcomes. Some organs from donors with high-grade tumors were underutilized, indicating a possible aversion by transplant clinicians or patients to use these organs.
These findings imply that it may be possible to safely expand organ usage from donors with primary brain tumors without negatively impacting outcomes, potentially benefiting many patients waiting for a transplant. Although this might lead to a slight rise in transplant numbers in the UK, the findings may hold particular significance for nations with stricter guidelines, such as the United States. The study’s findings can help transplant clinicians discuss the risks and benefits of accepting organ offers from such donors.
Consensus Document | The use of mechanical circulatory support in lung transplantation
11 Jan, 2023 | 14:18h | UTC
Commentary on Twitter
AATS announces the publication of “The use of mechanical circulatory support in lung transplantation" in #JTCVS! Read the AATS 2022 Expert Consensus Document: https://t.co/rNPCl6bzYK @mghartwigmd @AnkitBharatMD @MarceloCypel @KHoetzenecker @Machuca_TN @IsaOpitz @tssmn @AATSHQ pic.twitter.com/jU7JcJ0jeB
— AATS Journals (@AATSJournals) October 27, 2022
Special Issue | Lung transplantation.
10 Nov, 2022 | 13:30h | UTCIndications for Lung Transplantation and Patient Selection
Recipient Management before Lung Transplantation
Allocation of Donor Lungs in Korea
Donor Selection, Management, and Procurement for Lung Transplantation
Donation after Circulatory Death in Lung Transplantation
Ex Vivo Lung Perfusion in Lung Transplantatio
A Review of Anesthesia for Lung Transplantation
Technical Aspects of Lung Transplantation: General Considerations
Technical Aspects of Lung Transplantation: Adverse Events and Circumstances
Technical Aspects of Lung Transplantation: Pediatric and Lobar Transplantation
Technical Aspects of Combined Heart-Lung Transplantation
Critical Care Management Following Lung Transplantation
Surgical Complications Affecting the Early and Late Survival Rates after Lung Transplantation
Medical Complications of Lung Transplantation
Lung Transplantation for Patients with COVID-19 Acute Respiratory Distress Syndrome
Review: Primary graft dysfunction after clinical lung transplantation.
28 Jun, 2022 | 10:37h | UTC
Review: Dyspnea and cough in a lung transplant recipient.
7 Jun, 2022 | 11:16h | UTCDyspnea and cough in a lung transplant recipient – Cleveland Clinic Journal of Medicine
Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them.
29 Apr, 2022 | 10:51h | UTC
Commentary on Twitter
🆕💥Review Article @ASHE_Journal
Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them #IDTwitter #medtwitter #TwitteRx #MedEd https://t.co/ToPLQXtC4r pic.twitter.com/pZQWWb3ZSx— Antibiotic Steward Bassam Ghanem🆔🔥 (@ABsteward) April 28, 2022
Under a http://creativecommons.org/licenses/by/4.0/ license
Clinical characteristics and outcomes of patients with COVID-19–Associated Acute Respiratory Distress Syndrome who underwent lung transplant.
28 Jan, 2022 | 08:41h | UTC
Cases of lung transplantation for Covid-19–related respiratory failure in the US were associated with a three-month survival of 95.6%.
27 Jan, 2022 | 10:00h | UTCCommentaries:
New data on COVID-19 lung transplants – Cedars-Sinai Medical Center
~7 Percent of Lung Transplants Due to COVID-19 Respiratory Failure – HealthDay
RCT: Maribavir for refractory Cytomegalovirus infections with or without resistance post-transplant.
7 Dec, 2021 | 08:37h | UTC
How I Do It: Considering lung transplantation for patients with COVID-19.
24 Aug, 2021 | 09:55h | UTCHow I Do It: Considering lung transplantation for patients with COVID-19 – CHEST
Related:
Report: Lung transplantation for 3 patients with severe COVID-19
FDA authorizes additional Covid-19 vaccine dose for certain immunocompromised individuals – Other fully vaccinated individuals do not need an additional vaccine dose right now.
16 Aug, 2021 | 01:22h | UTCCommentaries:
CDC, FDA recommend COVID booster for immune-compromised – CIDRAP
FDA authorizes additional dose of Covid-19 vaccine for the immunocompromised – STAT
Covid booster: US approves third jab for the immunocompromised – BBC
CDC Panel Recommends 3rd Vaccine Dose For Immunocompromised People – NPR
6 Things To Know If You’re Immunocompromised And Considering A 3rd Shot – NPR
CDC recommends third Covid-19 vaccine dose for certain immunocompromised people – CNN
Commentary on Twitter
The Infectious Diseases Society of America (IDSA) supports the @FDA and @CDCgov's decision to authorize a supplemental vaccine dose for immunocompromised patients.
Read our statement: https://t.co/odzzSgIxnY pic.twitter.com/4PZfUwpjhM
— IDSA (@IDSAInfo) August 13, 2021
RCT: third dose of Moderna mRNA vaccine increases immunity in transplant recipients.
12 Aug, 2021 | 09:56h | UTCEditorial: Third Time’s a Charm — Covid-19 Vaccine Hope for Solid-Organ Transplant Recipients
Related:
[Preprint] 3rd AstraZeneca shot gives strong immunity.
Commentaries on Twitter
..1st randomized trial results of 3rd doses of Moderna vax for 120 people with organ transplants: month 4, their minimum anti-RBD antibody levels were 55% for 3rd dose vs 18% (still increasing a little in the placebo group). No cases of acute rejection https://t.co/BcfeyUEhx5 #IC
— Hilda Bastian, PhD (@hildabast) August 11, 2021
The authors conclude that a third-dose booster of mRNA-1273 vaccine should be considered for transplant recipients. https://t.co/Q3gakSaNjd pic.twitter.com/CMN8f7cq29
— NEJM (@NEJM) August 11, 2021
Review: Lung transplantation for interstitial lung disease.
5 Aug, 2021 | 08:32h | UTCLung transplantation for interstitial lung disease – European Respiratory Review
Three doses of an mRNA Covid-19 vaccine in solid-organ transplant recipients can improve the immunogenicity of the vaccine.
24 Jun, 2021 | 10:32h | UTC
Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.
15 Jun, 2021 | 08:59h | UTCCommentaries: For Transplant Recipients, Third Time May Be the Charm for Better COVID Vaccine Protection – Hopkins Medicine AND Extra COVID Vaccine May Help Protect Transplant Patients – Associated Press
Commentary on Twitter
Our report about 3rd vaccine doses in transplant patients is published! "It is encouraging that antibody titers increased after the 3rd dose in 1/3 of patients who had negative antibody titers and in all patients who had low-positive antibody titers"https://t.co/6XElwyIdAa
— Dorry Segev (@Dorry_Segev) June 14, 2021
Cohort study shows inadequate antibody response to mRNA SARS-CoV-2 vaccine among kidney transplant recipients.
6 May, 2021 | 09:01h | UTC
Commentary on Twitter
The studies of mRNA vax in people with transplants are getting bigger: still the same message. Some protection, but not enough. This time, 308 people with kidney transplants in Israel, BNT-Pfizer vaccine https://t.co/Otvt8F11my
— Hilda Bastian, PhD (@hildabast) May 6, 2021
Organ transplant recipients remain vulnerable to Covid-19 even after second vaccine dose.
6 May, 2021 | 09:03h | UTCOriginal Study: Antibody Response to 2-Dose SARS-CoV-2 mRNA Vaccine Series in Solid Organ Transplant Recipients – JAMA
Systematic review: Interventions for increasing solid organ donor registration
28 Apr, 2021 | 08:11h | UTCInterventions for increasing solid organ donor registration – Cochrane Library
Summary: Interventions for increasing solid organ donor registration – Cochrane Library
Japanese doctors perform world’s first living donor lung transplant to a Covid-19 patient
12 Apr, 2021 | 01:12h | UTCJapanese doctors perform world’s first living donor lung transplant to a Covid-19 patient – CNN
Review: Care for the organ transplant recipient on the intensive care unit
8 Apr, 2021 | 08:36h | UTCCare for the organ transplant recipient on the intensive care unit – Journal of Critical Care
Early outcomes after lung transplantation for severe COVID-19: a series of the first consecutive cases from four countries
5 Apr, 2021 | 01:49h | UTCCommentary: Criteria for selecting COVID-19 patients for lung lung transplantation – Medical University of Vienna
Commentary on Twitter
NEW Research—Lung transplantation is the only option for survival in some patients with severe, unresolving #COVID19-associated #ARDS
From Ankit Bharat & colleagues https://t.co/7u52IJSOIn, including a fantastic video abstract https://t.co/2cjfTLXR8R
— The Lancet Respiratory Medicine (@LancetRespirMed) April 1, 2021
Review: Post-Transplant Pregnancy and Contraception
23 Mar, 2021 | 02:10h | UTCPost-Transplant Pregnancy and Contraception – Clinical Journal of the American Society of Nephrology
Immunogenicity of a single dose of SARS-CoV-2 mRNA vaccine in solid organ transplant recipients
17 Mar, 2021 | 02:55h | UTC