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Transplantation – Lung

Extracorporeal CPR dissemination and integration with organ preservation in the USA: ethical and logistical considerations

28 Apr, 2023 | 12:47h | UTC

Extracorporeal cardiopulmonary resuscitation dissemination and integration with organ preservation in the USA: ethical and logistical considerations – Critical Care

 


Cold static preservation at 10°C shows promising results for safely extending lung transplantation timeframes

24 Apr, 2023 | 13:38h | UTC

Extension of Cold Static Donor Lung Preservation at 10°C – NEJM Evidence

 

Commentary on Twitter

 


Expanding Organ Usage: UK study finds organs from patients with a primary brain tumor are a viable option

27 Mar, 2023 | 13:27h | UTC

Summary: A national cohort study in the UK investigated the risk of cancer transmission from deceased donors with primary brain tumors to organ recipients. The study found no cases of brain tumor transmission among 778 transplants from 282 donors with primary brain tumors, including 262 from donors with high-grade tumors. Organ transplant survival was equivalent to that in matched controls, and some organs from donors with high-grade tumors were less likely to be transplanted.

The results suggest that the risk of cancer transmission in transplants from deceased donors with primary brain tumors is lower than previously thought. Furthermore, the study indicated that donors with brain tumors provided good-quality organs with favorable risk markers and excellent transplant outcomes. Some organs from donors with high-grade tumors were underutilized, indicating a possible aversion by transplant clinicians or patients to use these organs.

These findings imply that it may be possible to safely expand organ usage from donors with primary brain tumors without negatively impacting outcomes, potentially benefiting many patients waiting for a transplant. Although this might lead to a slight rise in transplant numbers in the UK, the findings may hold particular significance for nations with stricter guidelines, such as the United States. The study’s findings can help transplant clinicians discuss the risks and benefits of accepting organ offers from such donors.

Article: Organ Transplants From Deceased Donors With Primary Brain Tumors and Risk of Cancer Transmission – JAMA Surgery

 


Consensus Document | The use of mechanical circulatory support in lung transplantation

11 Jan, 2023 | 14:18h | UTC

The American Association for Thoracic Surgery (AATS) 2022 Expert Consensus Document: The use of mechanical circulatory support in lung transplantation – The Journal of Thoracic and Cardiovascular Surgery

 

Commentary on Twitter

 


Special Issue | Lung transplantation.

10 Nov, 2022 | 13:30h | UTC

Homepage

Indications for Lung Transplantation and Patient Selection

Recipient Management before Lung Transplantation

Allocation of Donor Lungs in Korea

Donor Selection, Management, and Procurement for Lung Transplantation

Donation after Circulatory Death in Lung Transplantation

Ex Vivo Lung Perfusion in Lung Transplantatio

A Review of Anesthesia for Lung Transplantation

Technical Aspects of Lung Transplantation: General Considerations

Technical Aspects of Lung Transplantation: Adverse Events and Circumstances

Technical Aspects of Lung Transplantation: Pediatric and Lobar Transplantation

Technical Aspects of Combined Heart-Lung Transplantation

Critical Care Management Following Lung Transplantation

Surgical Complications Affecting the Early and Late Survival Rates after Lung Transplantation

Medical Complications of Lung Transplantation

Lung Transplantation for Patients with COVID-19 Acute Respiratory Distress Syndrome

 


Review: Primary graft dysfunction after clinical lung transplantation.

28 Jun, 2022 | 10:37h | UTC

A Focused Review on Primary Graft Dysfunction after Clinical Lung Transplantation: A Multilevel Syndrome – Cells

 


Review: Dyspnea and cough in a lung transplant recipient.

7 Jun, 2022 | 11:16h | UTC

Dyspnea and cough in a lung transplant recipient – Cleveland Clinic Journal of Medicine

 


Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them.

29 Apr, 2022 | 10:51h | UTC

Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them – Antimicrobial Stewardship & Healthcare Epidemiology

 

Commentary on Twitter

Under a http://creativecommons.org/licenses/by/4.0/ license

 


Clinical characteristics and outcomes of patients with COVID-19–Associated Acute Respiratory Distress Syndrome who underwent lung transplant.

28 Jan, 2022 | 08:41h | UTC

Clinical Characteristics and Outcomes of Patients With COVID-19–Associated Acute Respiratory Distress Syndrome Who Underwent Lung Transplant – JAMA

Related: Cases of lung transplantation for Covid-19–related respiratory failure in the US were associated with a three-month survival of 95.6%.

 


Cases of lung transplantation for Covid-19–related respiratory failure in the US were associated with a three-month survival of 95.6%.

27 Jan, 2022 | 10:00h | UTC

Lung Transplantation for Covid-19–Related Respiratory Failure in the United States – New England Journal of Medicine

Commentaries:

New data on COVID-19 lung transplants – Cedars-Sinai Medical Center

~7 Percent of Lung Transplants Due to COVID-19 Respiratory Failure – HealthDay

 


RCT: Maribavir for refractory Cytomegalovirus infections with or without resistance post-transplant.

7 Dec, 2021 | 08:37h | UTC

Maribavir for Refractory Cytomegalovirus Infections With or Without Resistance Post-Transplant: Results from a Phase 3 Randomized Clinical Trial – Clinical Infectious Diseases

 


How I Do It: Considering lung transplantation for patients with COVID-19.

24 Aug, 2021 | 09:55h | UTC

How I Do It: Considering lung transplantation for patients with COVID-19 – CHEST

 

Related:

Early outcomes after lung transplantation for severe COVID-19: a series of the first consecutive cases from four countries

Report: Lung transplantation for 3 patients with severe COVID-19

 


FDA authorizes additional Covid-19 vaccine dose for certain immunocompromised individuals – Other fully vaccinated individuals do not need an additional vaccine dose right now.

16 Aug, 2021 | 01:22h | UTC

Coronavirus (COVID-19) Update: FDA Authorizes Additional Vaccine Dose for Certain Immunocompromised Individuals – U.S. Food & Drug Administration

Commentaries:

Statement on FDA Authorization of Supplemental Vaccine Dose for Immunocompromised Patients – Infectious Diseases Society of America

CDC, FDA recommend COVID booster for immune-compromised – CIDRAP

FDA authorizes additional dose of Covid-19 vaccine for the immunocompromised – STAT

The fine print: Understanding the new policy authorizing extra Covid vaccine doses for the immunocompromised – STAT

Covid booster: US approves third jab for the immunocompromised – BBC

CDC Committee Approves Third Covid-19 Shot For Immunocompromised People—Here’s Who Should Get One – Forbes

CDC Panel Recommends 3rd Vaccine Dose For Immunocompromised People – NPR

6 Things To Know If You’re Immunocompromised And Considering A 3rd Shot – NPR

CDC recommends third Covid-19 vaccine dose for certain immunocompromised people – CNN

 

Commentary on Twitter

 


RCT: third dose of Moderna mRNA vaccine increases immunity in transplant recipients.

12 Aug, 2021 | 09:56h | UTC

Randomized Trial of a Third Dose of mRNA-1273 Vaccine in Transplant Recipients – New England Journal of Medicine

Editorial: Third Time’s a Charm — Covid-19 Vaccine Hope for Solid-Organ Transplant Recipients

Related:

Study: Among kidney transplant recipients who did not respond after 2 doses, a third dose of an mRNA-1273 vaccine induced a serologic response in 49% of patients.

Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.

[Preprint] 3rd AstraZeneca shot gives strong immunity.

 

Commentaries on Twitter

 


Review: Lung transplantation for interstitial lung disease.

5 Aug, 2021 | 08:32h | UTC

Lung transplantation for interstitial lung disease – European Respiratory Review

 


Three doses of an mRNA Covid-19 vaccine in solid-organ transplant recipients can improve the immunogenicity of the vaccine.

24 Jun, 2021 | 10:32h | UTC

Three Doses of an mRNA Covid-19 Vaccine in Solid-Organ Transplant Recipients – New England Journal of Medicine

 


Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.

15 Jun, 2021 | 08:59h | UTC

Safety and Immunogenicity of a Third Dose of SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients: A Case Series – Annals of Internal Medicine

Commentaries: For Transplant Recipients, Third Time May Be the Charm for Better COVID Vaccine Protection – Hopkins Medicine AND Extra COVID Vaccine May Help Protect Transplant Patients – Associated Press

 

Commentary on Twitter

 


Cohort study shows inadequate antibody response to mRNA SARS-CoV-2 vaccine among kidney transplant recipients.

6 May, 2021 | 09:01h | UTC

Antibody response to mRNA SARS-CoV-2 vaccine among kidney transplant recipients – Prospective cohort study – Clinical Microbiology and Infection

 

Commentary on Twitter

 


Organ transplant recipients remain vulnerable to Covid-19 even after second vaccine dose.

6 May, 2021 | 09:03h | UTC

Organ Transplant Recipients Remain Vulnerable to Covid-19 Even After Second Vaccine Dose – Johns Hopkins Medicine

Original Study: Antibody Response to 2-Dose SARS-CoV-2 mRNA Vaccine Series in Solid Organ Transplant Recipients – JAMA

 


Systematic review: Interventions for increasing solid organ donor registration

28 Apr, 2021 | 08:11h | UTC

Interventions for increasing solid organ donor registration – Cochrane Library

Summary: Interventions for increasing solid organ donor registration – Cochrane Library

 


Japanese doctors perform world’s first living donor lung transplant to a Covid-19 patient

12 Apr, 2021 | 01:12h | UTC

Japanese doctors perform world’s first living donor lung transplant to a Covid-19 patient – CNN

 


Review: Care for the organ transplant recipient on the intensive care unit

8 Apr, 2021 | 08:36h | UTC

Care for the organ transplant recipient on the intensive care unit – Journal of Critical Care

 


Early outcomes after lung transplantation for severe COVID-19: a series of the first consecutive cases from four countries

5 Apr, 2021 | 01:49h | UTC

Early outcomes after lung transplantation for severe COVID-19: a series of the first consecutive cases from four countries – The Lancet Respiratory Medicine

Commentary: Criteria for selecting COVID-19 patients for lung lung transplantation – Medical University of Vienna

 

Commentary on Twitter

 


Review: Post-Transplant Pregnancy and Contraception

23 Mar, 2021 | 02:10h | UTC

Post-Transplant Pregnancy and Contraception – Clinical Journal of the American Society of Nephrology

 


Immunogenicity of a single dose of SARS-CoV-2 mRNA vaccine in solid organ transplant recipients

17 Mar, 2021 | 02:55h | UTC

Immunogenicity of a Single Dose of SARS-CoV-2 Messenger RNA Vaccine in Solid Organ Transplant Recipients – JAMA

 


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