Pathology
Consensus Recommendations | Standardizing pathologic evaluation of breast carcinoma after neoadjuvant chemotherapy.
23 Aug, 2022 | 12:52h | UTC
Spindle cell lesions of the breast: a diagnostic algorithm.
23 Aug, 2022 | 12:51h | UTC
Review | Drug regimens of novel antibiotics in critically ill patients with varying renal functions.
23 Aug, 2022 | 12:49h | UTC
Review | Barrett Esophagus.
17 Aug, 2022 | 14:26h | UTCBarrett Esophagus: A Review – JAMA (free for a limited period)
Audio clinical review: Barrett Esophagus – JAMA
Review | Liver biopsy in patients with alcohol-associated liver disease with acute-on-chronic liver failure.
22 Jul, 2022 | 11:28h | UTC
Guidelines on germline testing for urologic tumor syndromes.
15 Jul, 2022 | 12:49h | UTCGuidelines on Germline Testing for Urologic Tumor Syndromes – European Urology Focus
Review | The promise of precision medicine in rheumatology.
12 Jul, 2022 | 12:38h | UTCThe promise of precision medicine in rheumatology – Nature Reviews Rheumatology
Commentary on Twitter
A Review in @NatureMedicine discusses recent efforts to dissect cellular and molecular heterogeneity across multiple systemic autoimmune rheumatic diseases and future directions for implementing stratification approaches for SARD treatment. https://t.co/5EGTkQjasR pic.twitter.com/NAgbnyU96O
— Nature Portfolio (@NaturePortfolio) July 8, 2022
M-A | Does it really pay-off? Comparison of lymphadenectomy versus observational approach in skin melanoma with positive sentinel node biopsy.
12 Jul, 2022 | 12:37h | UTC
Evaluation of the molecular landscape of pediatric thyroid nodules and use of a multigene genomic classifier in children.
8 Jul, 2022 | 11:20h | UTC
Commentaries on Twitter
A multigene classifier reveals that malignant pediatric thyroid nodules have a unique molecular landscape vs those in adults. The classifier had a sensitivity of 96% & specificity of 78% for cancer detection & might reduce the need for diagnostic surgery: https://t.co/hdsPjGe9IR
— NatureRevClinOncol (@NatRevClinOncol) June 16, 2022
Pediatric thyroid cancer is on the rise. Its genomic landscape is unique; but, this retrospective case series shows that it may still be amenable to molecular classification—potentially decreasing diagnostic surgery & opening avenues for targeted therapy. https://t.co/KiYMsB1qGM
— JAMA Oncology (@JAMAOnc) June 10, 2022
Opinion | Renaming Gleason Score 6 prostate to noncancer: a flawed idea scientifically and for patient care.
30 Jun, 2022 | 10:44h | UTCOriginal Opinion Paper: Low-Grade Prostate Cancer: Time to Stop Calling It Cancer – Journal of Clinical Oncology
ASCO Guideline Update: Biomarkers for systemic therapy in metastatic breast cancer.
29 Jun, 2022 | 11:40h | UTC
Commentary on Twitter
‼️ 🆕 @ASCO guideline update published in #JCO by @lynnhenrymd et al: Biomarkers for #SystemicTherapy in Metastatic #BreastCancer ➡️ https://t.co/qAzT9WNKTF #bcsm #biomarkers @AngieDemichele pic.twitter.com/3WtAt8TK5w
— Journal of Clinical Oncology (@JCO_ASCO) June 27, 2022
Consensus report on anatomy, pathophysiology and clinical significance of the gastro-esophageal junction.
23 Jun, 2022 | 10:26h | UTC
Causes of liver cancer are changing around the world: some up, some down.
13 Jun, 2022 | 07:54h | UTCNews Release: Causes of Liver Cancer are Changing Around the World: Some Up, Some Down – UC San Diego Health
Original Study: Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of liver cancer – Cell Metabolism (link to abstract – $ for full-text)
Circulating tumor DNA as a biomarker in patients with stage III and IV Wilms tumor.
8 Jun, 2022 | 10:43h | UTCCommentary: Analysis of Circulating Tumor DNA as a Biomarker in Stage III and IV Wilms Tumor – The ASCO Post
#ASCO22 – RCT: Circulating tumor DNA analysis guiding adjuvant therapy in stage II colon cancer.
6 Jun, 2022 | 11:53h | UTCCirculating Tumor DNA Analysis Guiding Adjuvant Therapy in Stage II Colon Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: ctDNA Effectively Detects When Adjuvant Chemo Is Avoidable in Stage II Colon Cancers – Cancer Network
Commentary on Twitter
DYNAMIC: Among patients with stage II colon cancer, a ctDNA-guided management approach reduced the use of adjuvant chemotherapy without increasing the risk of recurrence. #ASCO22 https://t.co/xXjXyPXRC9 pic.twitter.com/gvHMnGWbyE
— NEJM (@NEJM) June 4, 2022
Review: Pathogenesis of alcohol-associated liver disease.
6 Jun, 2022 | 10:50h | UTCPathogenesis of Alcohol-Associated Liver Disease – Journal of Clinical and Experimental Hepatology
Cardiac metastasis from solid cancers: a 35-year single-center autopsy study.
3 Jun, 2022 | 10:54h | UTC
RCT: Effect of reflectance confocal microscopy for suspect lesions on diagnostic accuracy in melanoma.
2 Jun, 2022 | 10:41h | UTC
Commentary on Twitter
In this RCT, adjunctive use of reflectance confocal microscopy for suspicious lesions is proven to reduce unnecessary excisions and removes all aggressive melanomas at baseline in a real-life, prospective clinical decision making setting. https://t.co/cWJu9TlaEH
— JAMA Dermatology (@JAMADerm) June 1, 2022
M-A: Association between benign ovarian tumors and ovarian cancer risk.
2 Jun, 2022 | 10:18h | UTC
Redefining breast cancer subtypes to guide treatment prioritization and maximize response: Predictive biomarkers across 10 cancer therapies.
31 May, 2022 | 10:46h | UTC
Commentary on Twitter
Online Now: Redefining breast cancer subtypes to guide treatment prioritization and maximize response: Predictive biomarkers across 10 cancer therapies https://t.co/Im8F60VMjO
— Cancer Cell (@Cancer_Cell) May 27, 2022
A clinical severity index for eosinophilic esophagitis: development, consensus, and future directions.
30 May, 2022 | 11:29h | UTC
Commentary on Twitter
New in @AGA_Gastro: 1️⃣st ever severity index for eosinophilic esophagitis (#EoE)! We can now combine all elements of a patient’s disease activity into a single score to understand disease severity. Check it out ➡️ https://t.co/WgRiH47S6W @KhouryMD @LabMuir @DrGaryFalk #DDW2022 pic.twitter.com/Tyo6hltJ5r
— American Gastroenterological Association (AGA) (@AmerGastroAssn) May 20, 2022
Retrospective Cohort Study | Ovarian cancer detection in average-risk women: classic- versus nonclassic-appearing adnexal lesions.
30 May, 2022 | 10:58h | UTCNews Release: Researchers use ultrasound to predict ovarian cancer – Radiological Society of North America
Commentary: Appearance of Ovarian Lesions on Ultrasound May Predict Malignancy – HealthDay
Commentary on Twitter
Classifying adnexal lesion appearance as classic or nonclassic has high sensitivity and specificity for diagnosing malignancy in women at average risk for ovarian cancer. @BaranLab @drantil7 @kpatellippmann @katematuren @ayakamaya @hanna_zrad @LizSadowski https://t.co/6NphOIycMe pic.twitter.com/99DyWIHXwU
— Radiology (@radiology_rsna) March 28, 2022
Review: Autopsy in the era of advanced cardiovascular imaging.
30 May, 2022 | 10:49h | UTCAutopsy in the era of advanced cardiovascular imaging – European Heart Journal
Commentary on Twitter
Autopsy in the era of advanced cardiovascular imaging https://t.co/2sFRlhQ9Fh @escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/gJthaYph4M
— European Society of Cardiology Journals (@ESC_Journals) May 24, 2022
Under a https://creativecommons.org/licenses/by-nc/4.0/ license
Health Technology Assessment: Molecular testing for thyroid nodules of indeterminate cytology.
25 May, 2022 | 10:42h | UTC
Nonrandomized Controlled Trial: Clinical impact of intraoperative margin assessment in breast-conserving surgery with a novel Pegulicianine Fluorescence–guided system.
18 May, 2022 | 10:28h | UTC
Commentary on Twitter
New intraoperative margin detection technology is safe and reduces reexcision rates in patients undergoing breast conserving surgery! (include infographic) #bcsm https://t.co/NqUOhGJBo4
— JAMA Surgery (@JAMASurgery) May 11, 2022