Pathology
Cohort Study | 5-mm margins may be adequate for T1a melanoma excision near critical structures
16 May, 2023 | 14:40h | UTCAssociation of Excision Margin Size With Local Recurrence and Survival in Patients With T1a Melanoma at Critical Structures – JAMA Dermatology (link to abstract – $ for full-text)
Commentary: Melanoma Excisions with 5 Millimeter Margins Linked to Less Risk of Local Recurrence – HCP Live
Commentary on Twitter
Study on thin melanomas (T1a) near critical anatomic sites such as the head and face showed that 5-mm surgical margins may be safe for patients and decrease reconstructive surgery and potential adverse, including scarring and mental issues. https://t.co/Mw7Ub4xMVX
— JAMA Dermatology (@JAMADerm) April 12, 2023
An update on the role of immunohistochemistry in the evaluation of pancreatic/liver/gastrointestinal luminal tract disorders
15 May, 2023 | 13:02h | UTC
2023 Rectal cancer lexicon update | Revised consensus on terminology and staging
15 May, 2023 | 12:50h | UTC
RCT | Cancer stem cell assay-guided chemotherapy improves survival of patients with recurrent glioblastoma
12 May, 2023 | 13:18h | UTCNews Release: ChemoID platform-predicted treatments lead to longer survival for glioblastoma patients – University of Cincinnati
Commentary on Twitter
Online now: Cancer stem cell assay-guided chemotherapy improves survival of patients with recurrent glioblastoma in a randomized trial https://t.co/y5GYCCgg3b
— Cell Reports Medicine (@CellRepMed) May 3, 2023
Review | Applications of artificial intelligence in breast pathology
9 May, 2023 | 14:36h | UTC
Cohort Study | Skin biopsy yields 88% sensitivity in detecting meningococcal Purpura Fulminans
5 May, 2023 | 15:15h | UTC
Review | Updated salivary gland immunohistochemistry
5 May, 2023 | 14:55h | UTCUpdated Salivary Gland Immunohistochemistry: A Review – Archives of Pathology & Laboratory Medicine
Researchers develop an AI-based method to replace chemical staining of tissue
4 May, 2023 | 13:48h | UTCNews Release: Researchers develop an AI-based method to replace chemical staining of tissue – University of Turku
Original Study: Unstained Tissue Imaging and Virtual Hematoxylin and Eosin Staining of Histologic Whole Slide Images – Laboratorial Investigation
What is acute kidney injury? A visual guide
4 Apr, 2023 | 14:02h | UTCWhat is acute kidney injury? A visual guide – Nature
Practice Guide | Acquiring tissue for advanced lung cancer diagnosis and comprehensive biomarker testing
9 Mar, 2023 | 14:04h | UTC
Gadolinium nanoparticles detected in kidney tissue of patients after MRI with gadolinium contrast, raising safety concerns
20 Feb, 2023 | 12:24h | UTCSummary: Researchers have discovered that tiny particles of the rare earth metal gadolinium can infiltrate kidney cells, potentially causing side effects. These particles, used to enhance MRI scans, were found in human and rodent specimens in a study that used electron microscopy to detect them. Gadolinium is typically tightly bound to chelating molecules in MRI contrast agents so that it can be eliminated via the kidneys, but the researchers found that some particles can leach out and build up in tissues. This raises questions about the safety of contrast agents containing gadolinium, which are used in around 50% of MRI scans, and highlights the need for further research into the risks and potential harms associated with these agents.
Commentary: Expert left ‘astounded’ by gadolinium discovery – Health Imaging
Recent advances in the classification of gynecological tract tumors: updates from the 5th edition of the WHO “Blue Book”
16 Feb, 2023 | 14:35h | UTC
Study shows non-diabetic kidney disease is prevalent among individuals with diabetes undergoing renal biopsy
15 Feb, 2023 | 15:41h | UTCCommentary: Non-Diabetic Kidney Disease Prevalent in Individuals With Type 2 Diabetes – Consultant 360
Single-arm phase 2 study | Neoadjuvant pembrolizumab in localized microsatellite instability high/deficient mismatch repair solid tumors
24 Jan, 2023 | 14:19h | UTCNeoadjuvant Pembrolizumab in Localized Microsatellite Instability High/Deficient Mismatch Repair Solid Tumors – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentary: Neoadjuvant Pembrolizumab in Localized MSI-H/dMMR Solid Tumors – The ASCO Post
Glomerulonephritis: immunopathogenesis and immunotherapy
17 Jan, 2023 | 13:12h | UTCGlomerulonephritis: immunopathogenesis and immunotherapy – Nature Reviews Immunology (if the link is paywalled, try this one)
Commentary on Twitter
A Review in @NatRevImmunol proposes a new grouping of glomerulonephritis disorders based on their underlying immunopathogenesis, with a view to improving diagnosis, mechanistic understanding and treatment of these immune-mediated kidney diseases. https://t.co/5EsGFBpU3K pic.twitter.com/KULbWS0xMz
— Nature Portfolio (@NaturePortfolio) January 15, 2023
ASCO Guideline | Immunotherapy and biomarker testing in recurrent and metastatic head and neck cancers
9 Jan, 2023 | 14:41h | UTCNews Release: ASCO Publishes New Guideline on Immunotherapy, Biomarker Testing in Advanced Head and Neck Cancer – ASCO Daily News
Review | Role of AI and digital pathology for colorectal immuno-oncology.
16 Dec, 2022 | 13:11h | UTCRole of AI and digital pathology for colorectal immuno-oncology – British Journal of Cancer
Review | Acute and chronic alcoholic pancreatitis, including paraduodenal pancreatitis.
2 Dec, 2022 | 14:08h | UTC
Sudden cardiac death in the young: a consensus statement on recommended practices for cardiac examination by the pathologist.
17 Nov, 2022 | 12:27h | UTC
RCT | Transbronchial needle aspiration combined with cryobiopsy in the diagnosis of mediastinal diseases.
10 Nov, 2022 | 13:54h | UTCTransbronchial needle aspiration combined with cryobiopsy in the diagnosis of mediastinal diseases: a multicentre, open-label, randomised trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary on Twitter
NEW—Mediastinal cryobiopsy + standard EBUS-TBNA = significant improvement in diagnostic yield for mediastinal lesions. This combined approach is a valid first-line diagnostic tool for mediastinal diseases.
Study from Prof Felix Herth, & colleagues https://t.co/DGJCrKVDbI pic.twitter.com/cvG89hNIHS
— The Lancet Respiratory Medicine (@LancetRespirMed) October 24, 2022
Brief Review | Close collaboration between pathologists and intensivists to understand (not just) coronavirus disease.
4 Nov, 2022 | 13:37h | UTC
Commentary on Twitter
Pathologists & intensivists collaborating to understand (not just) #COVID19
➡️ facing an unknown entity: challenge in #ICU
➡️ lightening pathophysiological shadow: demand for autopsies
➡️ formalizing interdisciplinary exchange to optimize outcome#FOAMcc
🗞️https://t.co/0a48Vontzn pic.twitter.com/K9zTl5b8vp— Intensive Care Medicine (@yourICM) November 2, 2022
Guideline | Reporting of surgically removed lymph nodes for breast tumors.
25 Oct, 2022 | 13:20h | UTC
Cohort Study | Genetic sequencing of pancreatic cyst fluid reveals diverse genomic alterations that may guide clinical management.
20 Oct, 2022 | 12:24h | UTCNews Release: Genetic test for pancreatic cancer outperforms current guidelines – University of Pittsburgh
Commentary from the author on Twitter (thread – click for more)
A tweetorial on our study (https://t.co/OCqCRJEMdx). But, first a case: Young female w/ a 1.9 cm incidental pancreatic cyst. No concerning features, but KRAS, TP53 and SMAD4 mutations on molecular testing. Surgical resection: #IPMN w/ a small #PancreaticCancer. #Pathology #GIPath pic.twitter.com/hMJQ4OAUld
— Aatur Singhi, MD PhD (@PancPathologist) October 10, 2022
Study | Plaque histology and myocardial disease in sudden coronary death.
30 Sep, 2022 | 12:41h | UTC
Consensus Recommendations | Standardizing pathologic evaluation of breast carcinoma after neoadjuvant chemotherapy.
23 Aug, 2022 | 12:52h | UTC