Pathology
The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
7 May, 2021 | 08:30h | UTC
Commentary on Twitter
We forget that covid-19 is a new disease, never having been seen until late 2019, w/ different features than any prior illness. A truly outstanding review today on its pathophysiology https://t.co/8gx2w8r1xf @LancetRespirMed @osuchm and colleagues pic.twitter.com/WGIfI2nb9B
— Eric Topol (@EricTopol) May 6, 2021
Review: Histiocytosis
4 May, 2021 | 08:29h | UTC
Diagnosis and management of leukocytoclastic vasculitis
14 Apr, 2021 | 01:26h | UTCDiagnosis and management of leukocytoclastic vasculitis – Internal and Emergency Medicine
70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age
14 Mar, 2021 | 20:07h | UTC70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age – The Lancet Oncology (link to abstract – $ for full-text)
Pathological Evidence for SARS-CoV-2 as a Cause of Myocarditis: JACC Review Topic of the Week
4 Feb, 2021 | 01:27h | UTC
Commentary on Twitter
How common is COVID-19-induced myocarditis as evaluated by histologic examination of autopsy or EMB specimens? Short answer: its pretty uncommon. See our State of the Art Review in JACC this week. https://t.co/SlzQ4ICwTW
— Aloke Finn (@AlokeFinn) January 19, 2021
[Abstract Only] Systematic review and meta-analysis of native kidney biopsy complications
20 Oct, 2020 | 01:26h | UTCSystematic Review and Meta-Analysis of Native Kidney Biopsy Complications – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)
Commentary on Twitter
A meta-analysis found that although native kidney biopsy is an invasive diagnostic procedure, the rates of bleeding complications are low. Complications are more frequently seen after kidney biopsies of hospitalized patients with AKI. https://t.co/kxK6qxX1fc pic.twitter.com/SgCoI505cc
— CJASN (@CJASN) October 15, 2020
Image: SARS-CoV-2 infection of airway cells
4 Sep, 2020 | 02:15h | UTCImages in Clinical Medicine: SARS-CoV-2 Infection of Airway Cells – New England Journal of Medicine
Forty postmortem examinations in COVID-19 Patients: Two distinct pathologic phenotypes and correlation with clinical and radiologic findings
4 Sep, 2020 | 02:05h | UTC
Commentary on Twitter
Our COVID autopsy study is now online! We describe 2 distinct pathologic phenotypes and correlate with clinical and radiologic data. So proud of this team! 💕@ColumbiaPath @AJCPjournal #pulmpath #pathology #autopsy #NYC #COVID19 #covid https://t.co/f3xhc0v1si
— Simona De Michele, MD (@SDeMicheleMD) September 3, 2020
Histopathological findings and viral tropism in patients with severe fatal COVID-19: A post-mortem study
21 Aug, 2020 | 02:31h | UTCCommentary: Blood clots and lung injuries found in patients who have died of COVID-19 – Imperial College London
Peripheral blood examination findings in SARS-CoV-2 infection
10 Aug, 2020 | 01:58h | UTC
From ‘brain fog’ to heart damage, COVID-19’s lingering problems alarm scientists
3 Aug, 2020 | 00:57h | UTCFrom ‘brain fog’ to heart damage, COVID-19’s lingering problems alarm scientists – Science
How does SARS-CoV-2 cause COVID-19?
31 Jul, 2020 | 08:38h | UTCHow does SARS-CoV-2 cause COVID-19? – Science
Case report: Cardiac endotheliitis and multisystem inflammatory syndrome after COVID-19
30 Jul, 2020 | 10:18h | UTC
COVID-19 and cardiovascular disease: From basic mechanisms to clinical perspectives
27 Jul, 2020 | 10:01h | UTC
Non-invasive early detection of cancer four years before conventional diagnosis using a blood test
27 Jul, 2020 | 09:37h | UTC
COVID-19 autopsy in people who died in community settings
23 Jul, 2020 | 08:29h | UTC
Histopathology and ultrastructural findings of fatal COVID-19 infections
20 Jul, 2020 | 08:04h | UTC
Related Commentary on Twitter
NEW Case Series—Histopathology and ultrastructural findings of 14 fatal #COVID19 infections in Washington State shows primary pathology as diffuse alveolar damage, with virus located in the pneumocytes and tracheal epithelium @UWMedicinehttps://t.co/vZggyxhjU1 pic.twitter.com/AFeuiMiH26
— The Lancet (@TheLancet) July 17, 2020
Review: Extrapulmonary Manifestations of COVID-19
13 Jul, 2020 | 00:28h | UTCExtrapulmonary manifestations of COVID-19 – Nature Medicine
Related review: Extra‐pulmonary complications of COVID‐19: a multi‐system disease? – Journal of Medical Virology
Interactive Atlas: Inside the Coronavirus
24 Jun, 2020 | 03:32h | UTCInside the Coronavirus – Scientific American
“What scientists know about the inner workings of the pathogen that has infected the world”.
Related Commentary on Twitter
This is terrific! An interactive look at the novel coronovirus & how it infects humans, @markfischetti @FalconieriV @brittaspen – https://t.co/PbejT01doE #COVID19 #science @sciam kudos! to @laurahelmuth
— Elaine Schattner MD, MA (@ESchattner) June 23, 2020
Neuropathological Features of Covid-19
15 Jun, 2020 | 03:35h | UTCNeuropathological Features of Covid-19 – New England Journal of Medicine
Study Shows Abnormalities in Placentas from COVID-19-positive Pregnant Women
26 May, 2020 | 10:00h | UTCPlacental Pathology in COVID-19 – American Journal of Clinical Pathology
Commentaries: Placentas from COVID-19-positive pregnant women show injury – Northwestern University AND Expert reaction to study looking at placentas from COVID19-positive pregnant women – Science Media Centre AND Covid-19 appears to attack placenta during pregnancy, study says – CNN AND Placenta Injury Observed in Pregnant Women Who Test Positive For Coronavirus – Forbes
Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19
22 May, 2020 | 04:59h | UTCCommentary: Lungs of deceased COVID-19 patients show distinctive features – Brigham and Women’s Hospital
Related: Postmortem Examination of Patients With COVID-19 – JAMA AND Pulmonary Arterial Thrombosis in COVID-19 With Fatal Outcome: Results From a Prospective, Single-Center, Clinicopathologic Case Series – Annals of Internal Medicine AND Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19 – Journal of Thrombosis and Haemostasis
Autopsies Find High Incidence of Venous Thromboembolism in Patients with Covid-19
7 May, 2020 | 09:18h | UTCRelated Study: Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19 – Journal of Thrombosis and Haemostasis
Lung Pathology of COVID-19: Is AFOP in Play?
29 Apr, 2020 | 04:58h | UTCLung pathology of COVID-19: is AFOP in play? – PulmCrit
Pathological Evidence of Pulmonary Thrombotic Phenomena in Severe COVID-19
17 Apr, 2020 | 02:24h | UTC* We congratulate the authors for this significant contribution to the understanding of this disease.