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Nephrology

M-A: Adjuvant corticosteroids are effective in lowering the risk of kidney scarring in children with acute pyelonephritis

28 Feb, 2021 | 20:38h | UTC

Adjuvant corticosteroids for prevention of kidney scarring in children with acute pyelonephritis: a systematic review and meta-analysis – Archives of Disease in Childhood (link to abstract – $ for full-text)

 

ICU-based renal replacement therapy

25 Feb, 2021 | 08:23h | UTC

ICU-Based Renal Replacement Therapy – Critical Care Medicine

 

Commentary on Twitter

 

KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease

24 Feb, 2021 | 02:21h | UTC

Executive summary of the KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease – Kidney International

 

Commentary on Twitter (thread – Click for more)

 

Pro-con Debate: Starting antihypertensive drug treatment with combination therapy

23 Feb, 2021 | 01:26h | UTC

Con: Starting Antihypertensive Drug Treatment With Combination Therapy

Pro: Starting Antihypertensive Drug Treatment With Combination Therapy

 

M-A: Blood pressure effects of sodium reduction

23 Feb, 2021 | 01:28h | UTC

Blood Pressure Effects of Sodium Reduction: Dose-Response Meta-Analysis of Experimental Studies – Circulation

Commentaries: The Lower the Sodium, the Better for BP: Updated Meta-analysis – TCTMD AND AHA News: Lower Your Sodium, and Blood Pressure Will Follow – HealthDay

 

Study: In intensively treated hypertensive patients, a diastolic blood pressure of less than 60 mm Hg was associated with increased risk of cardiovascular events

19 Feb, 2021 | 02:37h | UTC

Evaluation of Optimal Diastolic Blood Pressure Range Among Adults With Treated Systolic Blood Pressure Less Than 130 mm Hg – JAMA Network Open

Commentary: Treated Diastolic Blood Pressure: How Low Is Too Low? – NEJM Journal Watch

 

Commentary on Twitter

 

RCT: Avacopan for the treatment of ANCA-associated vasculitis

18 Feb, 2021 | 02:50h | UTC

Avacopan for the Treatment of ANCA-Associated Vasculitis – New England Journal of Medicine (link to abstract – $ for full-text)

 

Systematic review: Urgent‐start peritoneal dialysis vs. hemodialysis for people with chronic kidney disease

15 Feb, 2021 | 00:46h | UTC

Urgent‐start peritoneal dialysis versus haemodialysis for people with chronic kidney disease – Cochrane Library

Summary: Urgent-start peritoneal dialysis versus haemodialysis for people with chronic kidney disease – Cochrane Library

 

M-A: No link between blood pressure drugs and falls

12 Feb, 2021 | 02:05h | UTC

No link between blood pressure drugs and falls, finds study – University of Oxford

Original study: Association between antihypertensive treatment and adverse events: systematic review and meta-analysis – The BMJ

 

Commentary on Twitter (thread – click for more)

 

Meta-analysis: Chlorthalidone vs. hydrochlorothiazide

11 Feb, 2021 | 02:00h | UTC

Chlorthalidone versus hydrochlorothiazide: major cardiovascular events, blood pressure, left ventricular mass, and adverse effects – Journal of Hypertension (link to abstract – $ for full-text)

Commentary: Chlorthalidone Compared With HCTZ for MACE Reduction – Renal & Urology News

 

Combination of vancomycin plus piperacillin and risk of acute kidney injury: a worldwide pharmacovigilance database analysis

11 Feb, 2021 | 01:50h | UTC

Combination of vancomycin plus piperacillin and risk of acute kidney injury: a worldwide pharmacovigilance database analysis – Journal of Antimicrobial Chemotherapy

Related: Risk of acute kidney injury and Clostridioides difficile infection with piperacillin/tazobactam, cefepime and meropenem with or without vancomycin – Clinical Infectious Diseases AND Vancomycin Plus Piperacillin-Tazobactam and Acute Kidney Injury in Adults: A Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract – $ for full-text) AND Association of Acute Kidney Injury With Concomitant Vancomycin and Piperacillin/Tazobactam Treatment Among Hospitalized Children – JAMA Pediatrics (link to abstract – $ for full-text) AND Co-administration of vancomycin and piperacillin-tazobactam is associated with increased renal dysfunction in adult and pediatric burn patients – Critical Care

 

Commentary on Twitter

 

RCT: No difference in kidney allograft survival in kidney transplant patients allocated to early corticosteroid cessation vs. long-term corticosteroid therapy

5 Feb, 2021 | 01:26h | UTC

Early Corticosteroid Cessation vs Long-term Corticosteroid Therapy in Kidney Transplant Recipients: Long-term Outcomes of a Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Commentary: Long-Term Corticosteroids Not Necessary After Kidney Transplant – Physician’s Weekly AND Is it OK to Cut Back on Prednisone After Kidney Transplant? – MedPage Today (free registration required)

 

Commentary on Twitter

 

SR/MA: Colistin nephrotoxicity

5 Feb, 2021 | 01:21h | UTC

Colistin Nephrotoxicity: Meta-analysis of Randomized Controlled Trials – Open Forum Infectious Diseases

 

Dialysis patients have 4-fold greater risk of dying from COVID-19

5 Feb, 2021 | 01:39h | UTC

News Release: Dialysis patients have 4-fold greater risk of dying from COVID-19 – Canadian Medical Association Journal

Original Study: COVID-19 in patients undergoing long-term dialysis in Ontario – Canadian Medical Association Journal

 

Consensus recommendations: Diagnosis and management of Bartter syndrome

3 Feb, 2021 | 01:04h | UTC

Diagnosis and management of Bartter syndrome: executive summary of the consensus and recommendations from the European Rare Kidney Disease Reference Network Working Group for Tubular Disorders – Kidney International

 

Podcast: Hypertension Update

2 Feb, 2021 | 01:07h | UTC

#254 Hypertension Update with Dr. Wanpen Vongpatanasin – The Curbsiders Internal Medicine Podcast

 

Review: Ambulatory blood pressure monitoring to diagnose and manage hypertension

25 Jan, 2021 | 01:24h | UTC

Ambulatory Blood Pressure Monitoring to Diagnose and Manage Hypertension – Hypertension

 

Meta-analysis: Early initiation of renal replacement therapy is not associated with survival benefit in critically ill patients with acute kidney injury

20 Jan, 2021 | 01:25h | UTC

Timing of renal replacement therapy initiation for acute kidney injury in critically ill patients: a systematic review of randomized clinical trials with meta-analysis and trial sequential analysis – Critical Care

 

Randomized trial: Preoperative exercise improves vascular caliber and maturation of arteriovenous fistula

19 Jan, 2021 | 01:33h | UTC

Effect of preoperative exercise on vascular caliber and maturation of arteriovenous fistula: the physicalfav trial, a randomized controlled study – Journal of Nephrology

 

Perspective: Addressing polypharmacy in outpatient dialysis units

19 Jan, 2021 | 01:27h | UTC

Addressing Polypharmacy in Outpatient Dialysis Units – Clinical Journal of the American Society of Nephrology

Related: Targeted Deprescribing in an Outpatient Hemodialysis Unit: A Quality Improvement Study to Decrease Polypharmacy – American Journal of Kidney Diseases (link to abstract – $ for full-text)

 

Meta-analysis of randomized trials: SGLT-2 inhibitors and GLP-1 receptor agonists reduce cardiovascular and renal outcomes in type 2 diabetes

15 Jan, 2021 | 08:41h | UTC

Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials – The BMJ

Calculator based on the results: interactive decision support tool for outcomes

 

Cohort study: Piperacillin/tazobactam linked to increased risk of acute kidney injury when compared to cefepime or meropenem

15 Jan, 2021 | 08:24h | UTC

Risk of acute kidney injury and Clostridioides difficile infection with piperacillin/tazobactam, cefepime and meropenem with or without vancomycin – Clinical Infectious Diseases

 

Commentary on Twitter

 

Study: Despite recommendations, less than 2 percent of patients with treatment-resistant hypertension were tested for primary aldosteronism in a large U.S. cohort

14 Jan, 2021 | 01:55h | UTC

Testing for Primary Aldosteronism and Mineralocorticoid Receptor Antagonist Use Among U.S. Veterans: A Retrospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Primary Aldosteronism Testing Rare in Treatment-Resistant HTN – HealthDay AND Primary Aldosteronism Testing Rare for Patients with Resistant Hypertension – NEJM Journal Watch

 

Commentary from the author on Twitter (thread – click for more)

 

ACR Consensus Statement: Use of intravenous gadolinium-based contrast media in patients with kidney disease

14 Jan, 2021 | 01:52h | UTC

Use of Intravenous Gadolinium-based Contrast Media in Patients with Kidney Disease: Consensus Statements from the American College of Radiology and the National Kidney Foundation – Radiology

 

Commentary on Twitter

 

A randomized trial of albumin infusion to prevent intradialytic hypotension in hospitalized hypoalbuminemic patients

14 Jan, 2021 | 01:42h | UTC

A randomized trial of albumin infusion to prevent intradialytic hypotension in hospitalized hypoalbuminemic patients – Critical Care

 

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