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Nephrology

Management of Diabetes Mellitus in patients with CKD: Core Curriculum 2022.

17 Oct, 2021 | 21:23h | UTC

Management of Diabetes Mellitus in Patients With CKD: Core Curriculum 2022 – American Journal of Kidney Diseases

 


Home Hemodialysis: Core Curriculum 2021.

14 Oct, 2021 | 09:55h | UTC

Home Hemodialysis: Core Curriculum 2021 – American Journal of Kidney Diseases

 

Commentary on Twitter

 


Consensus Guidance: Hyperkalemia management in the emergency department.

13 Oct, 2021 | 01:34h | UTC

Hyperkalemia management in the emergency department: An expert panel consensus – Journal of the American College of Emergency Physicians Open

Related: Review: Clinical Management of Hyperkalemia. Classification and monitoring, when to reinitiate RAASi therapy, use oral K+-binding agents, and more

Podcast: Hyperkalemia, Diet, K+ Binders, Exercise

Hyperkalemia: Pathophysiology, Risk Factors and Consequence

Hyperkalemia: Pathophysiology, Risk Factors and Consequence (several articles)

 


Study suggests a 30-second interval between automated office blood pressure measurements is as accurate and reliable as a 60-second interval.

8 Oct, 2021 | 10:09h | UTC

Impact of 30- Versus 60-Second Time Intervals Between Automated Office Blood Pressure Measurements on Measured Blood Pressure – Hypertension (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Genetic testing in the diagnosis of chronic kidney disease: recommendations for clinical practice.

7 Oct, 2021 | 10:17h | UTC

Genetic testing in the diagnosis of chronic kidney disease: recommendations for clinical practice – Nephrology Dialysis Transplantation

 

Commentary on Twitter

 


Long-Term Immunosuppression Management: Opportunities and Uncertainties.

7 Oct, 2021 | 10:15h | UTC

Long-Term Immunosuppression Management: Opportunities and Uncertainties – Clinical Journal of the American Society of Nephrology

 

Commentary on Twitter

 


Nephrotoxicity of cancer therapeutic drugs: Focusing on novel agents.

7 Oct, 2021 | 10:14h | UTC

Nephrotoxicity of cancer therapeutic drugs: Focusing on novel agents – Kidney Research and Clinical Practice

 


Cohort study: Adding a new antihypertensive to existing regimens is associated with greater blood pressure reductions than maximizing dose.

6 Oct, 2021 | 09:57h | UTC

Adding a New Medication Versus Maximizing Dose to Intensify Hypertension Treatment in Older Adults: A Prospective Observational Study – Annals of Internal Medicine

News release: When blood pressure needs more control, what’s better: An additional drug or more of the same? – Michigan Medicine

Commentary: Adding an antihypertensive to existing regimens associated with greater BP reduction than maximizing dose, with some caveats in adherence – ACP Internist

Related: #ESCCongress – RCT: Initial hypertension treatment with a single pill with 4 drugs at quarter doses (irbesartan 37.5 mg, amlodipine 1.25 mg, indapamide 0.625 mg, and bisoprolol 2.5 mg) achieved better BP lowering vs. standard monotherapy (irbesartan 150 mg).

 

Commentary on Twitter (thread – click for more)

 


Is salt good for you after all? The evidence says no.

6 Oct, 2021 | 08:52h | UTC

Is salt good for you after all? The evidence says no – The Conversation

Related:

#ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

Systematic Review: Altered dietary salt intake for people with chronic kidney disease.

New WHO benchmarks help countries reduce salt intake and save lives.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Meta-Analysis: Effect of Reduction in Dietary Sodium on Blood Pressure Levels

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

 


Podcast: Urinary Stone Disease.

5 Oct, 2021 | 08:50h | UTC

#298 Urinary Stone Disease Will Rock Your World – The Curbsiders

 


Review: Membranous nephropathy.

1 Oct, 2021 | 10:01h | UTC

Membranous nephropathy – Nature Reviews Disease Primers (free for a limited period)

Infographic: Membranous nephropathy (free for a limited period)

 

Commentary on Twitter

 


Review: Monitoring of Treatment for Arterial Hypertension.

29 Sep, 2021 | 09:59h | UTC

Monitoring of Treatment for Arterial Hypertension – Deutsches Ärzteblatt International

 


Expert panel recommends against use of race in assessment of kidney function.

24 Sep, 2021 | 09:01h | UTC

Expert panel recommends against use of race in assessment of kidney function – STAT

Original Guidance: A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease – American Journal of Kidney Diseases

 

Commentary on Twitter

 


Landmark articles suggest eliminating race in the estimation of kidney function.

24 Sep, 2021 | 09:03h | UTC

Editorial: Time to Eliminate Health Care Disparities in the Estimation of Kidney Function – New England Journal of Medicine

Study 1: New Creatinine- and Cystatin C–Based Equations to Estimate GFR without Race – New England Journal of Medicine

Study 2: Race, Genetic Ancestry, and Estimating Kidney Function in CKD – New England Journal of Medicine

Commentaries:

NIH-supported study suggests alternative to race-based kidney function calculations – NIH News Releases

Remove Race From Equation Used to Assess Kidney Function, Researchers Say – AJMC

Researchers identify potential approach to eliminate race from equations to estimate kidney function – News Medical

 

Commentary on Twitter

 


KDIGO 2021 clinical practice guideline for the management of glomerular diseases.

21 Sep, 2021 | 09:05h | UTC

KDIGO 2021 clinical practice guideline for the management of glomerular diseases – Kidney Disease: Improving Global Outcomes

Executive summary: KDIGO 2021 Guideline for the Management of Glomerular Diseases – Kidney Disease: Improving Global Outcomes

 


Systematic Review: Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement therapy.

16 Sep, 2021 | 09:53h | UTC

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement therapy – Cochrane Library

Summary: Non-pharmacological interventions for preventing clotting of extracorporeal circuits during continuous kidney replacement therapy – Cochrane Library

 


Covid-19: Infection increases the risk of kidney disease even in mild cases, finds study.

10 Sep, 2021 | 05:33h | UTC

Covid-19: Infection increases the risk of kidney disease even in mild cases, finds study – The BMJ

Original study: Kidney Outcomes in Long COVID – Journal of the American Society of Nephrology

 


Long COVID and kidney disease.

10 Sep, 2021 | 05:31h | UTC

Long COVID and kidney disease – Nature Reviews Nephrology

 


NICE Guideline: Assessment and management of chronic kidney disease.

1 Sep, 2021 | 09:47h | UTC

Chronic kidney disease: assessment and management – National Institute for Health and Care Excellence

 


Study shows that current definitions of chronic kidney disease overestimate the CKD burden in older individuals and results in overdiagnosis.

1 Sep, 2021 | 09:43h | UTC

Accounting for Age in the Definition of Chronic Kidney Disease – JAMA Internal Medicine (free for a limited period)

Invited commentary: Overdiagnosis of Chronic Kidney Disease in Older Adults—An Inconvenient Truth – JAMA Internal Medicine (free for a limited period)

 

Commentary on Twitter

 


#ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

29 Aug, 2021 | 19:21h | UTC

Effect of Salt Substitution on Cardiovascular Events and Death – New England Journal of Medicine (link to abstract – $ for full-text)

News release: Low-sodium salt prevents stroke – European Society of Cardiology

Commentary: Massive SSaSS Study Shows Switch to Salt Substitute Cuts Stroke, CVD – TCTMD

 

Commentary on Twitter

 


#ESCCongress – RCT: Finerenone reduced CV events in patients with kidney disease and type 2 diabetes (12.4% vs. 14.2% during a median follow-up of 3.4 years), but the risk of hyperkalemia was increased (10.8% vs. 5.3%).

29 Aug, 2021 | 18:14h | UTC

Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes – New England Journal of Medicine

News release: Finerenone benefits patients with diabetes across spectrum of kidney disease – European Society of Cardiology

Commentaries:

Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease – FIGARO-DKD – American College of Cardiology

FIGARO-DKD and FIDELITY Findings Show Benefits of Finerenone to Improve Outcomes in Patients With Kidney Disease, Diabetes – American College of Cardiology

Related:

[Abstract Only] Randomized trial: Effect of Finerenone on chronic kidney disease outcomes in Type 2 diabetes

 

Commentary on Twitter

 


#ESCCongress – RCT: Initial hypertension treatment with a single pill with 4 drugs at quarter doses (irbesartan 37.5 mg, amlodipine 1.25 mg, indapamide 0.625 mg, and bisoprolol 2.5 mg) achieved better BP lowering vs. standard monotherapy (irbesartan 150 mg).

29 Aug, 2021 | 18:11h | UTC

Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Quadruple UltrA-low-dose tReaTment for hypErTension – QUARTET – American College of Cardiology

 


New WHO Guideline for the pharmacological treatment of hypertension in adults.

26 Aug, 2021 | 08:57h | UTC

Guideline for the pharmacological treatment of hypertension in adults – World Health Organization

Related: WHO: More than 700 million people with untreated hypertension – Number of people living with hypertension has doubled to 1.28 billion since 1990.

 

Commentary on Twitter (thread – click for more)

 


Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants.

25 Aug, 2021 | 08:56h | UTC

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants – The Lancet

Commentary: Global and national high blood pressure burden and control – The Lancet (free registration required)

 

Commentary on Twitter

 


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