Pain Medicine
Guideline for opioid therapy and chronic noncancer pain
10 May, 2017 | 18:26h | UTCGuideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free) (RT @IrfanDhalla and @jendlake see Tweet)
Mortality risk during and after opioid substitution treatment
28 Apr, 2017 | 16:36h | UTCEditorial: Opioid substitution treatment is linked to reduced risk of death in opioid use disorder – The BMJ (free)
Commentary: Opioid Substitution Therapy Associated with Reduced Mortality – Physician’s First Watch (free)
Opioid substitution treatment seems to be associated with decreased mortality.
Advil, Motrin and other NSAIDs painkillers should be prescription only, Danish study says
28 Apr, 2017 | 16:37h | UTCAdvil, Motrin and other NSAIDs painkillers should be prescription only, Danish study says – Pittsburgh Post-Gazette (free) (RT @medpagetodaysee Tweet)
Original article: Non-steroidal anti-inflammatory drug use is associated with increased risk of out-of-hospital cardiac arrest: a nationwide case–time–control study – European Heart Journal – Cardiovascular Pharmacotherapy (free)
See more commentaries on this study in our March 17 issue, see #5.
After Knee or Hip Replacement, No Place Like Home
27 Apr, 2017 | 16:28h | UTCAfter Knee or Hip Replacement, No Place Like Home – The New York Times (10 articles per month are free)
See also: Time to Rethink Inpatient Rehab After Knee Replacement? – The Rheumatologist (free)
Original article abstract ($ for full-text): Effect of Inpatient Rehabilitation vs a Monitored Home-Based Program on Mobility in Patients With Total Knee Arthroplasty: The HIHO Randomized Clinical Trial – JAMA (free)
The NYT commentary talks about the futility of some interventions currently used to postpone surgery and about the benefits of outpatient rehabilitation.
New warnings about the use of codeine and tramadol
24 Apr, 2017 | 15:32h | UTCFDA Safety Alert: Codeine and Tramadol Medicines: Drug Safety Communication – Restricting Use in Children, Recommending Against Use in Breastfeeding Women (free)
FDA Statement: New warnings about the use of codeine and tramadol in children & nursing mothers (free)
Commentaries on the statement: FDA: Codeine Now Contraindicated for Pain and Cough in Kids – Physician’s First Watch (free) AND Codeine cough syrup should not be given to kids, FDA warns – STAT News (free)
These drugs should not be used at all for children younger than 12 years, and their use should also be limited in some older children.
EULAR revised recommendations for the management of fibromyalgia
12 Apr, 2017 | 15:52h | UTCEULAR revised recommendations for the management of fibromyalgia – Annals of Rheumatic Diseases (free)
Source: EULAR Revised Recommendations for the Management of Fibromyalgia – Medscape (free registration required)
Neuropathic pain in adults
3 Apr, 2017 | 19:23h | UTC
Pregabalin for Acute and Chronic Sciatica
23 Mar, 2017 | 17:15h | UTCTrial of Pregabalin for Acute and Chronic Sciatica – New England Journal of Medicine (link to abstract – $ required for full-text)
Pregabalin did not reduce pain and was associated with higher incidence of adverse events.