Infectious Diseases (all articles)
New WHO guidance on the role of HIV viral suppression in improving individual health and reducing transmission
24 Jul, 2023 | 13:17h | UTCNews Release: New WHO guidance on HIV viral suppression and scientific updates released at IAS 2023 – World Health Organization
WHO Guidance: The role of HIV viral suppression in improving individual health and reducing transmission – Word Health Organization
Related WHO Guidelines:
WHO recommends optimizing HIV testing services – World Health Organization
Primary health care and HIV: convergent actions – World Health Organization
Systematic Review | Low-level HIV viremia (below 1000 copies/mL) linked to minimal sexual transmission risk
24 Jul, 2023 | 13:15h | UTCThe risk of sexual transmission of HIV in individuals with low-level HIV viraemia – The Lancet
Editorial: HIV is sexually untransmittable when viral load is undetectable – The Lancet
Related: Study: Growing Acceptability of “Undetectable = Untransmittable” but Widespread Misunderstanding of HIV Transmission Risk Persists (several texts on the subject)
Commentary on Twitter
People on ART with low but detectible levels of HIV viral load have almost zero risk of sexually transmitting the virus to others, in-depth review suggests #IAS2023https://t.co/wU26C8cEMK pic.twitter.com/hQHLDqPxO6
— The Lancet (@TheLancet) July 22, 2023
Cohort Study | Increased risk of depression and suicide among people with HIV, especially in the first two years post-diagnosis
24 Jul, 2023 | 13:01h | UTC
Commentary on Twitter
Risk of Depression in People With HIV: A nationwide population-based matched cohort study
✅ Just Accepted
? Freely Availablehttps://t.co/nyrzPqRRqw— Clinical Infectious Diseases (@CIDJournal) July 22, 2023
RCT | Long-term Doxycycline for COPD does not reduce exacerbations, except possibly in severe cases or with low eosinophils
24 Jul, 2023 | 12:50h | UTCA Double-Blind, Randomised, Placebo-controlled Trial of Long-Term Doxycycline Therapy on Exacerbation Rate in Patients with Stable COPD – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
M-A | Exposure to smoke, overcrowding, poor living conditions, and contact with TB cases identified as risk conditions for pediatric TB
24 Jul, 2023 | 12:43h | UTC
Correspondence | Potential “healthy vaccinee bias” in a study of BNT162b2 vaccine against Covid-19
21 Jul, 2023 | 13:43h | UTC
Commentary from the author on Twitter (thread – click for more)
Our correspondence is out in @njem written w @VPrasadMDMPH & Ram Duriseti
We show v strong evidence of healthy vaccinee bias in an Israeli study of Pfizer booster vs covid death, which wasn't disclosed
Could explain ALL reported benefit of the booster?https://t.co/F3WeafvUnw pic.twitter.com/b29YQ0lblh
— Tracy Høeg, MD, PhD (@TracyBethHoeg) July 20, 2023
Phase 2 Trial | Maternal GBS6 vaccine shows promise in infant group B strep prevention
21 Jul, 2023 | 13:34h | UTCCommentary: Maternal strep B vaccine slashes risk of infection among infants – CIDRAP
RCT | Molecular screening for bacterial vaginosis does not significantly reduce preterm birth rates
21 Jul, 2023 | 13:31h | UTCSee also: Visual Abstract
IDSA 2023 Guidance on the treatment of antimicrobial resistant gram-negative infections
20 Jul, 2023 | 11:15h | UTC
RCT | Direct oral challenge noninferior to skin testing followed by direct oral challenge in low-risk penicillin allergy patients
18 Jul, 2023 | 13:54h | UTCEfficacy of a Clinical Decision Rule to Enable Direct Oral Challenge in Patients With Low-Risk Penicillin Allergy: The PALACE Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
See also: Visual Abstract
News Release: World-first clinical trial to help millions with penicillin allergies – Vanderbilt University Medical Center
Commentary: Trial supports use of direct oral challenge for penicillin allergy – CIDRAP
Cohort study | Poor sensitivity of procalcitonin-on-admission for ruling out bloodstream infections in patients with suspected sepsis
18 Jul, 2023 | 13:39h | UTCReliability of Admission Procalcitonin Testing for Capturing Bacteremia Across the Sepsis Spectrum: Real-World Utilization and Performance Characteristics, 65 U.S. Hospitals, 2008–2017 – Critical Care Medicine (link to abstract – $ for full-text)
Review | Infection prevention and control in the medical imaging environment
18 Jul, 2023 | 13:31h | UTC
Guideline | Antibiotic therapy in patients with suspected antibiotic allergy
17 Jul, 2023 | 13:59h | UTC
Systematic Review | Criteria to achieve safe antimicrobial intravenous-to-oral switch in hospitalized adult populations
17 Jul, 2023 | 13:34h | UTC
Case Series | Cutibacterium acnes endocarditis often misdiagnosed due to absence of typical symptoms and delayed culture results
17 Jul, 2023 | 13:31h | UTC
Cohort Study | Long-acting antiretroviral therapy may achieve virologic suppression in HIV patients with adherence challenges
17 Jul, 2023 | 13:26h | UTCDemonstration Project of Long-Acting Antiretroviral Therapy in a Diverse Population of People With HIV – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Long-Acting ART Achieves Virologic Suppression for People With HIV – HealthDay
Consensus Paper | Implementing strategies to prevent infections in acute-care settings
14 Jul, 2023 | 13:03h | UTCNews Release: New guidance for infection prevention in acute care settings – Society for Healthcare Epidemiology of America
Related:
Practice Recommendation | Strategies to prevent MRSA transmission and infection in hospitals
Consensus Paper | Strategies to prevent surgical site infections in acute-care hospitals
Consensus Paper | Strategies to prevent Clostridioides difficile infections in acute-care hospitals
Quality Improvement Study | Improved asymptomatic bacteriuria management by reduction of unnecessary urine culture requests
14 Jul, 2023 | 12:54h | UTCRelated:
Study: Hospital Intervention Resulted in a 45% Reduction in the Urine Cultures Ordered
USPSTF Recommendation Statement: Screening for Asymptomatic Bacteriuria in Adults
IDSA Guideline for the Management of Asymptomatic Bacteriuria
Commentary on Twitter
???Powerful message from our new study in @JAMAInternalMed: diagnostic stewardship (better use of diagnostic tests) was responsible for ALL the⬇️in unnecessary antibiotic use for ASB. ➕results??nudge to action. Time to??upstream to improve care! https://t.co/yO4UpA6ZKK pic.twitter.com/hXZGvNmVJP
— Valerie Vaughn (@ValerieVaughnMD) July 11, 2023
Retrospective Analysis | 18% of ICU patients develop sepsis-associated AKI, mostly stage 1, diagnosed by low urine output
12 Jul, 2023 | 13:39h | UTC
Commentary on Twitter
Fulminant myocarditis in #ICU
?short/long‑term prognosis
?clinical suspicion, initial recognition, differential diagnoses
?initial management & temporary #MCS: IABP #ECMO #Impella
?endomyocardial biopsy
?immunomodulatory therapies
?#FOAMcc @yourICM
?️https://t.co/JIGm4p0tv5 pic.twitter.com/o4RctuurEL— Intensive Care Medicine (@yourICM) July 11, 2023
Intervention Study | Pharmacist review may reduce antibiotic overuse at discharge
12 Jul, 2023 | 13:37h | UTCCommentary: Pharmacist review identifies improper antibiotic prescriptions – CIDRAP
Practice Recommendation | Strategies to prevent MRSA transmission and infection in hospitals
10 Jul, 2023 | 14:02h | UTCCommentary: New guidelines recommend antibiotic stewardship for preventing MRSA – CIDRAP
Global Burden of Disease Study | Understanding global trends of infectious diseases in younger population, 1990-2019
10 Jul, 2023 | 13:54h | UTCNews Release: Global efforts to reduce infectious diseases must extend beyond early childhood – Murdoch Children’s Research Institute
Commentary: Global infectious disease burden shifting from younger to older youth – CIDRAP
Podcast | Untangling catheter associated UTIs
10 Jul, 2023 | 13:21h | UTC#402 Don’t Get Caught with a CAUTI – The Curbsiders
Review | Post-COVID Conditions
7 Jul, 2023 | 16:21h | UTCPost-COVID Conditions – Mayo Clinic Proceedings
Consensus Paper | The place of new antibiotics for Gram-negative bacterial infections in intensive care
7 Jul, 2023 | 16:15h | UTC