TOP 10 Medical News Stories

“Most people are resilient after disasters, and only a small percentage develop chronic conditions. But in a nation of 328 million, small percentages become large numbers when translated into absolute terms.”

7 – The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings – Brain

Commentaries: The coronavirus may cause brain damage, even in patients with mild cases, a new study found – Business Insider AND Scientists warn of potential wave of COVID-linked brain damage – Reuters AND Coronavirus pandemic could cause wave of brain damage, scientists warn – CNN

8 – Assessment of patients who tested positive for COVID-19 after recovery – The Lancet Infectious Diseases

9 – Baloxavir Marboxil for Prophylaxis against Influenza in Household Contacts – New England Journal of Medicine

Commentary: Baloxavir Helps Prevent Flu in Exposed Household Contacts – NEJM Journal Watch

10 –COVID-19 Updates / 09 July 2020 Edition

09 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Wed July 08 – 10 Stories of The Day!

8 Jul, 2020 | 01:07h | UTC

1 – Preventing the next pandemic – Zoonotic diseases and how to break the chain of transmission – United Nations

Commentary: Coronavirus: world treating symptoms, not cause of pandemics, says UN – The Guardian

2 – School openings across globe suggest ways to keep coronavirus at bay, despite outbreaks – Science

3 – COVID-19-associated acute respiratory distress syndrome: is a different approach to management warranted? – The Lancet Respiratory Medicine

4 – Standardized Management for Hypoxemic Respiratory Failure and ARDS: Systematic Review & Meta-analysis – Chest

5 – Reset Sustainable Development Goals for a pandemic world – Nature

6 – In a new hospital ranking, doing good counts nearly as much as doing well – STAT

Lown Institute Hospital Index: Hospitals Serve Individuals AND Communities

7 – Draft Recommendation Statement: Lung Cancer Screening – U.S Preventive Services Task Force

Commentaries: Proposed changes to lung cancer screening guidance could increase scans among Black patients, women – STAT

8 – Methotrexate is not an additional risk factor for interstitial lung disease in RA patients – News Medical

9 – Comparative effectiveness of biological medicines in rheumatoid arthritis: systematic review and network meta-analysis including aggregate results from reanalysed individual patient data – The BMJ

Commentary: Lessons from a network meta-analysis of biologics in rheumatoid arthritis – The BMJ Opinion

10 –COVID-19 Updates / 08 July 2020 Edition

08 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Tue July 07 – 10 Stories of The Day!

7 Jul, 2020 | 09:06h | UTC

1 – It is Time to Address Airborne Transmission of COVID-19 – Clinical Infectious Diseases

Commentaries: Global experts: Ignoring airborne COVID spread risky – CIDRAP AND Coronavirus can float in air and WHO and CDC should tell people that, experts say – CNN AND Expert reaction to commentary about potential airborne transmission of the SARS-CoV-2 virus – Science Media Centre

2 – Data show panic and disorganization dominate the study of Covid-19 drugs – STAT

3 – WHO: access to HIV medicines severely impacted by COVID-19 as AIDS response stalls – World Health Organization

Commentary: Pandemic tops 11.5 million cases, imperils HIV care – CIDRAP

4 – Developing a SARS-CoV-2 Vaccine at Warp Speed – JAMA

Related Video: Coronavirus Vaccine Development – JAMA

5 – The Development of COVID-19 Vaccines: Safeguards Needed – JAMA

6 – Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study – The Lancet

Commentaries: SARS-CoV-2 seroprevalence in COVID-19 hotspots – The Lancet AND Spain’s coronavirus antibodies study adds evidence against herd immunity – CNN

7 – Clinical Validity of Serum Antibodies to SARS-CoV-2: A Case–Control Study – Annals of Internal Medicine

8 – A Comprehensive Review of Manifestations of Novel Coronaviruses in the Context of Deadly COVID-19 Global Pandemic – The American Journal of Medical Sciences

9 – Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline: Executive Summary – Clinical Infectious Diseases

10 –COVID-19 Updates / 07 July 2020 Edition

07 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Mon July 06 – 10 Stories of The Day!

6 Jul, 2020 | 09:05h | UTC

1 – ACMT Position Statement: Medication Administration and Safety During the Response to COVID-19 Pandemic – Journal of Medical Toxicology

2 – WHO discontinues hydroxychloroquine and lopinavir/ritonavir treatment arms for COVID-19 – World Health Organization

Commentary: WHO says trials show malaria and HIV drugs don’t cut Covid-19 hospital deaths – The Guardian

3 – Study Publications Must Be Up-To-Date in Covid Time – Absolutely Maybe Blog, by Hilda Bastian

Original Study: Treatment with Hydroxychloroquine, Azithromycin, and Combination in Patients Hospitalized with COVID-19 – International Journal of Infectious Diseases

4 – One U.K. trial is transforming COVID-19 treatment. Why haven’t others delivered more results? – Science

Study 1 – lopinavir-ritonavir: No clinical benefit from use of lopinavir-ritonavir in hospitalised COVID-19 patients studied in RECOVERY

Study 2 – dexamethasone: Low-cost dexamethasone reduces death by up to one third in hospitalised patients with severe respiratory complications of COVID-19 – Recovery Trial AND Effect of Dexamethasone in Hospitalized Patients with COVID-19: Preliminary Report – medRxiv

Study 3 – hydroxychloroquine: No clinical benefit from use of hydroxychloroquine in hospitalised patients with COVID-19

5 – 239 Experts With 1 Big Claim: The Coronavirus Is Airborne – The New York Times

“… in an open letter to the W.H.O., 239 scientists in 32 countries have outlined the evidence showing that smaller particles can infect people, and are calling for the agency to revise its recommendations. The researchers plan to publish their letter in a scientific journal next week.”

6 – COVID-19: This model shows why masks and social distancing are so important – World Economic Forum

7 – How to Safely Reopen Colleges and Universities During COVID-19: Experiences From Taiwan – Annals of Internal Medicine

Editorial: Reopening Colleges and Universities During the COVID-19 Pandemic

8 – Convalescent Plasma for COVID-19. A randomized clinical trial – medRxiv

9 – Six months of pandemic photography – Science

10 –COVID-19 Updates / 06 July 2020 Edition

06 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Fri July 03 – 10 Stories of The Day!

3 Jul, 2020 | 08:49h | UTC

1 – Coronavirus Update With Anthony Fauci – JAMA

2 – Selected Articles: COVID-19 in Surgical Patients

Article 1: Managing COVID-19 in Surgical Systems – Annals of Surgery

Article 2: Surgical Training During and After COVID-19: A Joint Trainee and Trainers Manifesto – Annals of Surgery

Article 3: COVID-19 – Considerations and Implications for Surgical Learners – Annals of Surgery

Article 4: Perioperative COVID-19 Defense: An Evidence-Based Approach for Optimization of Infection Control and Operating Room Management – Anesthesia & Analgesia

Article 5: A Guide for Surgical and Procedural Recovery After the First Surge of Covid-19 – NEJM Catalyst

3 – Distribution of Transmission Potential during Non-Severe COVID-19 Illness – Clinical Infectious Diseases

4 – Neurological associations of COVID-19 – The Lancet Neurology

5 – Risk of Ischemic Stroke in Patients with Coronavirus Disease 2019 (COVID-19) vs Patients with Influenza – JAMA Neurology

Commentaries: Stroke appears 8 times more likely with COVID than with flu – MedicalXpress AND Comparing COVID-19’s stroke rate with those of other respiratory infections – Cardiovascular Business

6 – Characteristics of Adult Outpatients and Inpatients with COVID-19 — 11 Academic Medical Centers, United States, March–May 2020 – CDC Morbidity and Mortality Weekly Report

Commentaries: Most COVID-19 patients don’t know who infected them, CDC survey finds – USA Today AND Despite Lockdowns Many Americans Likely Contracted Coronavirus From Strangers – Medical Daily AND Many Americans with COVID-19 don’t know how they got infected, survey suggests – Live Sciences

7 – SARS‐CoV‐2 endothelial infection causes COVID‐19 chilblains: histopathological, immunohistochemical and ultraestructural study of 7 paediatric cases – British Journal of Dermatology

News Release: Study supports link between COVID-19 and ‘COVID Toes’ – Wiley

8 – Apgar Score and Risk of Neonatal Death among Preterm Infants – New England Journal of Medicine

Commentaries: Apgar score effective in assessing health of preterm infants – Karolinska Institutet AND Apgar scores provide prognostic information for survival of preterm infants – 2 Minute Medicine AND Decreasing Apgar Scores Ups Risk of Neonatal Mortality in Preterm Infants – Physician’s Weekly

9 – Effect of alcohol on blood pressure – Cochrane Library

Summary: Alcohol has a biphasic effect on blood pressure and increases heart rate – Cochrane Library

10 –COVID-19 Updates / 03 July 2020 Edition

03 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Thu July 02 – 10 Stories of The Day!

2 Jul, 2020 | 08:56h | UTC

1 – Diagnostic accuracy of serological tests for covid-19: systematic review and meta-analysis – The BMJ

2 – Excess Deaths From COVID-19 and Other Causes, March-April 2020 – JAMA

Editorial: Mortality and Morbidity: The Measure of a Pandemic

Author Interview: Estimation of Excess Deaths From COVID-19 in the United States

Commentaries: About 30% of COVID deaths may not be classified as such – CIDRAP AND Study: 35 percent of excess deaths in pandemic’s early months tied to causes other than COVID-19 – Virginia Commonwealth University

3 – COVID-19 and the cardiovascular system: A review of current data, summary of best practices, outline of controversies, and illustrative case reports – American Heart Journal

4 – The prevalence of symptoms in 24,410 adults infected by the novel coronavirus (SARS-CoV-2; COVID-19): A systematic review and meta-analysis of 148 studies from 9 countries – PLOS One

5 – Accelerating Development of SARS-CoV-2 Vaccines — The Role for Controlled Human Infection Models – New England Journal of Medicine

6 – Visualizing the effectiveness of face masks in obstructing respiratory jets – Physics of Fluids

Commentaries: New Paper Shows Why Face Masks Are Essential In Curbing Covid-19 – Forbes AND Face Mask Construction, Materials Matter for Containing Coughing, Sneezing Droplets – American Institute of Physics

7 – The Moral Imperative to Include Pregnant Women in Clinical Trials of Interventions for COVID-19 – Annals of Internal Medicine

8 – The ethics of COVID-19 treatment studies: too many are open, too few are double-masked – CEBM Oxford

9 – Evidence does not support vitamin D for reducing respiratory infections, reviews conclude – The BMJ

10 –COVID-19 Updates / 02 July 2020 Edition

02 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Wed July 01 – 10 Stories of The Day!

1 Jul, 2020 | 08:00h | UTC

1 – Editorial: Is a “Cytokine Storm” Relevant to COVID-19? – JAMA Internal Medicine

2 – Editorial: Will COVID-19 be evidence-based medicine’s nemesis? – PLOS Medicine

“In the current fast-moving pandemic, where the cost of inaction is counted in the grim mortality figures announced daily, implementing new policy interventions in the absence of randomized trial evidence has become both a scientific and moral imperative.”

3 – Whole-town study reveals more than 40% of COVID-19 infections had no symptoms – Imperial College London

Original Study: Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo’ – Nature

4 – The line is forming for a COVID-19 vaccine. Who should be at the front? – Science

5 – Why COVID-19 Silent Hypoxemia is Baffling to Physicians – American Journal of Respiratory and Critical Care Medicine

Commentary: Silent Hypoxemia from COVID-19 Explained – Journal Feed

6 – Outcomes from intensive care in patients with COVID‐19: a systematic review and meta‐analysis of observational studies – Anaesthesia

7 – COVID-19 Planning Considerations: Guidance for School Re-entry – American Academy of Pediatrics

Commentaries: U.S. Pediatricians Call For In-Person School This Fall – NPR AND Academic, mental and physical benefits of in-person school outweigh virus risks, pediatrics group says – CNN AND Why a Pediatric Group Is Pushing to Reopen Schools This Fall – The New York Times

8 – Twin epidemics of covid-19 and non-communicable disease – The BMJ

9 – Swine flu strain with human pandemic potential increasingly found in pigs in China – Science

Original Study: Prevalent Eurasian avian-like H1N1 swine influenza virus with 2009 pandemic viral genes facilitating human infection – Proceedings of the National Academy of Sciences

10 –COVID-19 Updates / 01 July 2020 Edition

01 July 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Tue June 30 – 10 Stories of The Day!

30 Jun, 2020 | 08:12h | UTC

1 – No clinical benefit from use of lopinavir-ritonavir in hospitalised COVID-19 patients studied in RECOVERY

Commentary: Expert reaction to statement from RECOVERY trial on lopinavir-ritonavir in hospitalised COVID-19 patients, reporting no clinical benefit – Science Media Centre

2 – Immunity to COVID-19 is probably higher than tests have shown – Karolinska Institutet

Original Study: Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19 – bioRxiv

3 – Coronavirus: could it be burning out after 20% of a population is infected? – The Conversation

4 – Studies: Childhood Multisystem Inflammatory Syndrome — A New Challenge in the Pandemic

Study 1: Multisystem Inflammatory Syndrome in U.S. Children and Adolescents – New England Journal of Medicine

Study 2: Multisystem Inflammatory Syndrome in Children in New York State – New England Journal of Medicine

Editorial: Childhood Multisystem Inflammatory Syndrome — A New Challenge in the Pandemic – New England Journal of Medicine

Commentaries: Worrisome details noted in kids with COVID inflammatory syndrome – CIDRAP AND Researchers report nearly 300 cases of inflammatory syndrome tied to Covid-19 in kids – STAT

5 – COVID-19 rapid evidence summary: vitamin D for COVID-19 – National Institute for Health and Care Excellence

6 – Why N95 Should Be the Standard for All COVID-19 Inpatient Care – Annals of Internal Medicine

7 – Worldwide Effect of COVID-19 on Physical Activity: A Descriptive Study – Annals of Internal Medicine

8 – Recommendation Regarding the Use of Ivermectin as a Treatment for COVID-19, 22 June 2020 – Pan American Health Organization

9 – Considerations for Wearing Cloth Face Coverings – Centers for Disease Control and Prevention

10 –COVID-19 Updates / 30 June 2020 Edition

30 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Mon June 29 – 10 Stories of The Day!

29 Jun, 2020 | 09:21h | UTC

1 – Pediatric Airway Management in COVID-19 Patients: Consensus Guidelines From the Society for Pediatric Anesthesia’s Pediatric Difficult Intubation Collaborative and the Canadian Pediatric Anesthesia Society – Anesthesia & Analgesia

2 – Recommendations for Hospital-Based Physical Therapists Managing Patients With COVID-19 – Physical Therapy

3 – Editorial Evaluation and Peer Review During a Pandemic: How Journals Maintain Standards – JAMA

4 – COVID-19 in 7780 pediatric patients: A systematic review – EClinicalMedicine

Commentary: Children more resilient against coronavirus, study reveals – University of Texas Health Science Center at San Antonio

5 – Novel use of home pulse oximetry monitoring in COVID‐19 patients discharged from the emergency department identifies need for hospitalization – Academic Emergency Medicine

Commentary: Pulse Oximetry in Outpatients with COVID-19 – NEJM Journal Watch

6 – Incidence and Severity of COVID-19 in HIV-Positive Persons Receiving Antiretroviral Therapy: A Cohort Study – Annals of Internal Medicine

7 – Solve the “medicine by press release” problem with registered reports – Medium

8 – British Society of Gastroenterology (BSG)-led multisociety consensus care bundle for the early clinical management of acute upper gastrointestinal bleeding – Frontline Gastroenterology

9 – Updated Guidelines to Reduce Venous Thromboembolism in Trauma Patients: A Western Trauma Association Critical Decisions Algorithm – Trauma and Acute Care Surgery

10 –COVID-19 Updates / 29 June 2020 Edition

29 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Fri June 26 – 10 Stories of The Day!

26 Jun, 2020 | 09:29h | UTC

1 – Clinical guide for the management of critical care for adults with COVID-19 during the Coronavirus pandemic – Intensive Care Society

2 – The National Institutes of Health COVID-19 Treatment Guidelines Panel Provides Recommendations for Dexamethasone in Patients with COVID-19

3 – Antibody tests for identification of current and past infection with SARS‐CoV‐2 – Cochrane Library

News Release: New Cochrane review assesses how accurate antibody tests are for detecting COVID-19 – Cochrane Library

Commentaries: New Cochrane review assesses how accurate antibody tests are for detecting COVID-19 – Wiley AND Expert reaction to Cochrane Review of antibody tests for SARS-CoV-2 – Science Media Centre AND Covid-19: Timing is critical for antibody tests, finds Cochrane review – The BMJ

4 – Covid-19 antibody tests: a briefing – The BMJ

Commentary: Coronavirus: Antibody test lacks ‘proper assessment’ – BBC

5 – I’m a viral immunologist. Here’s what antibody tests for Covid-19 tell us – The Guardian

6 – Masks: The Easiest Way to Save Lives and Spare Jobs – Think Global Health

7 – Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study – The Lancet Psychiatry

Commentary: When Covid-19 hits the brain, it can cause strokes, psychosis and a dementia-like syndrome, new survey shows – STAT

8 – COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study – The Lancet Child & Adolescent Health

9 – Randomized Re-Opening of Training Facilities during the COVID-19 pandemic – medRxiv

10 –COVID-19 Updates / 26 June 2020 Edition

26 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Fri June 25 – 10 Stories of The Day!

25 Jun, 2020 | 08:32h | UTC

1 – Masks for Prevention of Respiratory Virus Infections, Including SARS-CoV-2, in Health Care and Community Settings: A Living Rapid Review – Annals of Internal Medicine

2 – COVID-19 and Public Interest in Face Mask Use – American Journal of Respiratory and Critical Care Medicine

Commentary: Countries with Early Adoption of Face Masks Showed Modest COVID-19 Infection Rates – American Thoracic Society

3 – Ten considerations for effectively managing the COVID-19 transition – Nature Human Behaviour

4 – Coronavirus Q&A: The Next COVID-19 Phase – JAMA

5 – Audio Interview: The Challenges of Safe Reopening – New England Journal of Medicine

6 – Effect of Colchicine vs Standard Care on Cardiac and Inflammatory Biomarkers and Clinical Outcomes in Patients Hospitalized With Coronavirus Disease 2019: The GRECCO-19 Randomized Clinical Trial – JAMA Network Open

Commentaries: Colchicine for the Treatment of Myocardial Injury in Patients With Coronavirus Disease 2019 (COVID-19)—An Old Drug With New Life? – JAMA Network Open AND In early trial, an ancient drug shows promise against severe COVID-19 – MedicalXpress

7 – Intrafamilial Exposure to SARS-CoV-2 Induces Cellular Immune Response without Seroconversion – medRxiv

Commentary: Exposure to SARS-CoV-2 can induce virus-specific T cell responses without seroconversion – News Medical

8 – Commercial influence and covid-19 – The BMJ

9 – Five ways to ensure that models serve society: a manifesto – Nature

“Pandemic politics highlight how predictions need to be transparent and humble to invite insight, not blame.”

10 –COVID-19 Updates / 25 June 2020 Edition

25 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Wed June 24 – 10 Stories of The Day!

24 Jun, 2020 | 03:38h | UTC

1 – Management of patients with liver derangement during the COVID-19 pandemic: an Asia-Pacific position statement – The Lancet Gastroenterology & Hepatology

2 – Measurement of airborne particle exposure during simulated tracheal intubation using various proposed aerosol containment devices during the COVID‐19 pandemic – Anaesthesia

3 – Inside the Coronavirus – Scientific American

“What scientists know about the inner workings of the pathogen that has infected the world”.

4 – How ‘Superspreading’ Events Drive Most COVID-19 Spread – Scientific American

“As few as 10 percent of infected people may drive a whopping 80 percent of cases, in specific types of situations”.

5 – Infographic. Graduated return to play guidance following COVID-19 infection – British Journal of Sports Medicine

6 – Dexamethasone & COVID – a study in immunopathology, evidence-based medicine, and ourselves – PulmCrit

7 – Early gestational diabetes screening in obese women: a randomized controlled trial – American Journal of Obstetrics & Gynecology

8 – Use of an electronic decision support tool to reduce polypharmacy in elderly people with chronic diseases: cluster randomised controlled trial – The BMJ

Commentary: Reduction of polypharmacy by electronic decision support—less is more – The BMJ Opinion

9 – Ultrasound for airway management: An evidence-based review for the emergency clinician – The American Journal of Emergency Medicine (free for 50 days)

10 –COVID-19 Updates / 24 June 2020 Edition

24 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Tue June 23 – 10 Stories of The Day!

23 Jun, 2020 | 08:52h | UTC

1 – Effect of Dexamethasone in Hospitalized Patients with COVID-19: Preliminary Report – medRxiv

Article press release from a few days ago: Dexamethasone Reduces Death by Up to One Third in Patients with Severe COVID-19

2 – Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19

3 – Use of Tracheostomy During the COVID-19 Pandemic: CHEST/AABIP/AIPPD: Expert Panel Report – CHEST

4 – Position Paper for the State-of-the-Art Application of Respiratory Support in Patients with COVID-19 – Respiration

5 – A compendium answering 150 questions on COVID‐19 and SARS‐CoV‐2 – Allergy

6 – What is the evidence to support the 2-metre social distancing rule to reduce COVID-19 transmission? – CEBM Oxford

7 – Ethics for surgeons during the COVID-19 pandemic, review article – Annals of Medicine and Surgery

8 – Potential Indirect Effects of the COVID-19 Pandemic on Use of Emergency Departments for Acute Life-Threatening Conditions — United States, January–May 2020 – Centers for Disease Control and Prevention

Commentary: The COVID-19 Pandemic Kept Thousands of People From Getting Urgent Medical Care, CDC Says – TIME

9 – Self-Measured Blood Pressure Monitoring at Home: A Joint Policy Statement from the American Heart Association and American Medical Association – Circulation

News Release: American Heart Association and American Medical Association urge broader adoption of self-measured blood pressure monitoring – American Medical Association

10 –COVID-19 Updates / 23 June 2020 Edition

23 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Mon June 22 – 10 Stories of The Day!

21 Jun, 2020 | 23:48h | UTC

1 – Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections – Nature Medicine

Commentaries: Chinese study: Antibodies in COVID-19 patients fade quickly – CIDRAP AND Coronavirus antibodies may disappear 2 to 3 months after people recover, a new study found – Business Insider AND New insights can change everything we know about coronavirus antibodies – BGR – News Beezer AND Expert reaction to study looking at the immune response of 37 asymptomatic people with confirmed SARS-CoV-2 infection – Science Media Centre AND You May Have Antibodies After Coronavirus Infection. But Not for Long – The New York Times

2 – NIH halts clinical trial of hydroxychloroquine – NIH News Releases

3 – COVID-19 Evidence is lacking for 2 meter distancing – CEBM Oxford

4 – Association of Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker Use With COVID-19 Diagnosis and Mortality – JAMA

Editorial: Renin-Angiotensin-Aldosterone Inhibitors and Susceptibility to and Severity of COVID-19 – JAMA

5 – COVID-19 Clinical Guidance for Pediatric Patients with Rheumatic Disease – American College of Rheumatology

News Release: COVID-19: ACR issues draft pediatric guidance – Medicine Matters

6 – Clinical Guidance for Pediatric Patients with Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 and Hyperinflammation in COVID-19 – American College of Rheumatology

7 – SARS-CoV-2 Infection in Infants Less than 90 Days Old – Journal of Pediatrics

Commentary: Babies with COVID-19 tend to have mild illness, mostly with fever – MedicalXpress

8 – Feasibility and physiological effects of prone positioning in non-intubated patients with acute respiratory failure due to COVID-19 (PRON-COVID): a prospective cohort study – The Lancet Respiratory Medicine

Commentaries: Prone positioning in non-intubated patients with COVID-19: raising the bar – The Lancet Respiratory Medicine AND Prone position ups oxygenation in patients with severe COVID-19 – MedicalXpress

9 – Characteristics Associated With Out-of-Hospital Cardiac Arrests and Resuscitations During the Novel Coronavirus Disease 2019 Pandemic in New York City – JAMA Cardiology

Editorial: Heroism in the Face of the COVID-19 Pandemic

Commentary: 911 calls for heart attack tripled in New York City during COVID-19 outbreak, victims more likely to die, study finds – AZCentral

10 –COVID-19 Updates / 22 June 2020 Edition

22 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Fri June 19 – 10 Stories of The Day!

19 Jun, 2020 | 09:49h | UTC

1 – Use of N95, Surgical, and Cloth Masks to Prevent COVID-19 in Health Care and Community Settings: Living Practice Points From the American College of Physicians (Version 1) – Annals of Internal Medicine

News Release: Living Practice Points from ACP: Advice on Use of N95, Surgical, and Cloth Masks to Prevent COVID-19 – American College of Physicians

2 – We Need Better Masks – Harvard Business Review

3 – Challenges of “Return to Work” in an Ongoing Pandemic – New England Journal of Medicine

4 – COVID-19 Is Far More Lethal Than Influenza – Medium

5 – How likely are kids to get Covid-19? Scientists see a ‘huge puzzle’ without easy answers – STAT

6 – The other infectious diseases spreading in the shadow of the pandemic – Vox

7 – Depression, Pain, Breathing Problems—and That’s After Surviving COVID-19 – Global Health NOW

Related: Report Suggests Some ‘Mildly Symptomatic’ Covid-19 Patients Endure Serious Long-Term Effects (other commentaries on the subject)

8 – Limited Role for Antibiotics in COVID-19: Scarce Evidence of Bacterial Coinfection – medRxiv

9 – Ethical dilemmas due to the Covid-19 pandemic – Annals of Intensive Care

10 –COVID-19 Updates / 19 June 2020 Edition

19 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Thu June 18 – 10 Stories of The Day!

18 Jun, 2020 | 09:14h | UTC

1 – Genomewide Association Study of Severe Covid-19 with Respiratory Failure – New England Journal of Medicine

Commentary: Study ties blood type to COVID-19 risk; O may help, A hurt – Associated Press

2 – Community Use Of Face Masks And COVID-19: Evidence From A Natural Experiment Of State Mandates In The US – Health Affairs

Commentary: Face mask requirements may have prevented 450,000 coronavirus cases – BGR

3 – Diabetes and COVID-19: Risks, Management, and Learnings from Other National Disasters – Diabetes Care

4 – Prone Positioning in Awake, Nonintubated Patients With COVID-19 Hypoxemic Respiratory Failure – JAMA Internal Medicine

Invited Commentary: Prone Positioning in Awake, Nonintubated Patients With COVID-19: Necessity Is the Mother of Invention – JAMA Internal Medicine

5 – Audio Interview: A Look at SARS-CoV-2 Transmission – New England Journal of Medicine

6 – Household secondary attack rate of COVID-19 and associated determinants in Guangzhou, China: a retrospective cohort study – The Lancet Infectious Diseases

Invited Commentary: Household studies provide key insights on the transmission of, and susceptibility to, SARS-CoV-2 – The Lancet Infectious Diseases

7 – Guidance on diagnosis, prevention and treatment of thromboembolic complications in COVID-19: a position paper of the Brazilian Society of Thrombosis and Hemostasis and the Thrombosis and Hemostasis Committee of the Brazilian Association of Hematology, Hemotherapy and Cellular Therapy – Hematology, Transfusion and Cell Therapy

8 – World Health Organization to Include Dexamethasone In Updated COVID-19 Care Guidelines; Drops Hydroxychloroquine From Massive Solidarity Trial – Health Policy Watch

9 – Update Alert: Should Clinicians Use Chloroquine or Hydroxychloroquine Alone or in Combination With Azithromycin for the Prophylaxis or Treatment of COVID-19? Living Practice Points From the American College of Physicians – Annals of Internal Medicine

10 –COVID-19 Updates / 18 June 2020 Edition

18 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Wed June 17 – 10 Stories of The Day!

17 Jun, 2020 | 02:51h | UTC

1 – Low-cost dexamethasone reduces death by up to one third in hospitalised patients with severe respiratory complications of COVID-19 – Recovery Trial

Commentaries: Coronavirus breakthrough: dexamethasone is first drug shown to save lives – Nature AND WHO welcomes preliminary results about dexamethasone use in treating critically ill COVID-19 patients – World Health Organization AND Major study finds common steroid reduces deaths among patients with severe Covid-19 – STAT AND Dexamethasone reduces death in hospitalised patients with severe respiratory complications of COVID-19 – University of Oxford AND Coronavirus: Dexamethasone proves first life-saving drug – BBC

2 – Effectiveness of isolation, testing, contact tracing, and physical distancing on reducing transmission of SARS-CoV-2 in different settings: a mathematical modelling study – The Lancet Infectious Diseases

Commentary: Case isolation, contact tracing, and physical distancing are pillars of COVID-19 pandemic control, not optional choices – The Lancet Infectious Diseases

3 – A Visual Guide to the SARS-CoV-2 Coronavirus – Scientific American

4 – Coronavirus Antibody Tests Have a Mathematical Pitfall – Scientific American

5 – How deadly is the coronavirus? Scientists are close to an answer – Nature

6 – Age-dependent effects in the transmission and control of COVID-19 epidemics – Nature Medicine

Commentary: People under 20 half as likely to catch Covid-19, study finds – CNN AND Expert reaction to new paper looking at age and COVID-19 susceptibility and severity – Science Media Centre

7 – Ibuprofen use and clinical outcomes in COVID-19 patients – Clinical Microbiology and Infection

8 – COVID-19: Pandemic surgery guidance – 4open

Commentary: Surgical guidance in the time of COVID-19 – SciencePOD

9 – The Science Behind the Search for a Covid-19 Vaccine – University of Melbourne

10 –COVID-19 Updates / 17 June 2020 Edition

17 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Tue June 16 – 10 Stories of The Day!

16 Jun, 2020 | 08:25h | UTC

1 – How to avoid the virus as the world reopens – Financial Times

2 – Coronavirus Q&A: Clinical Update with Carlos del Rio, MD

3 – Coronavirus Disease 2019 Case Surveillance — United States, January 22–May 30, 2020 – Centers for Disease Control and Prevention

Commentary: COVID-19 patients with underlying health conditions are 12 times more likely to die: CDC – The Hill

4 – Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study – The Lancet Global Health

Commentaries: COVID-19: rethinking risk – The Lancet Global Health AND Study Finds 1 in 5 People Worldwide at Risk of Severe Covid-19 – The New York Times

5 – Renal dysfunction in hospitalised children with COVID-19 – The Lancet Child & Adolescent Health

6 – Coronavirus (COVID-19) Update: FDA Revokes Emergency Use Authorization for Chloroquine and Hydroxychloroquine – U.S. Food & Drug Administration

Commentaries: FDA Withdraws Emergency Use Authorization For Hydroxychloroquine – NPR AND FDA revokes authorization of drug Trump touted – CNN

7 – Natural History of Asymptomatic SARS-CoV-2 Infection – New England Journal of Medicine

8 – Coronavirus: wastewater can tell us where the next outbreak will be – The Conversation

9 – Levels of SARS-CoV-2 RNA in sewage rose with COVID-19 cases in Dutch cities – American Chemical Society

Original Study: Presence of SARS-Coronavirus-2 RNA in Sewage and Correlation with Reported COVID-19 Prevalence in the Early Stage of the Epidemic in The Netherlands – Environmental Science & Technology Letters

10 –COVID-19 Updates / 16 June 2020 Edition

16 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Mon June 15 – 10 Stories of The Day!

15 Jun, 2020 | 03:50h | UTC

1 – Identifying airborne transmission as the dominant route for the spread of COVID-19 – Proceedings of the National Academy of Sciences

Commentaries: Face masks critical in preventing spread of COVID-19 – Texas A&M University AND Expert reaction to a study looking at mandatory face masks and number of COVID-19 infections in New York, Wuhan and Italy – Science Media Centre

2 – Wear a mask? Yes, always wear a mask – Institute for Health Metrics and Evaluation

3 – The Masks Masquerade – Medium

4 – European Resuscitation Council COVID-19 Guidelines Executive Summary – Resuscitation

5 – Acute kidney injury in critically ill patients with COVID-19 – Intensive Care Medicine

6 – COVID ‐19: a global threat to the nervous system – Annals of Neurology

Commentary: COVID-19 threatens the entire nervous system – Northwestern University

7 – A systematic review of neurological manifestations of SARS‐CoV‐2 infection: the devil is hidden in the details – European Journal of Neurology

8 – Neuropathological Features of Covid-19 – New England Journal of Medicine

9 – New-Onset Diabetes in Covid-19 – New England Journal of Medicine

Commentary: Expert reaction to letter warning of new-onset diabetes in COVID-19 patients – Science Media Centre

10 –COVID-19 Updates / 15 June 2020 Edition

15 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Fri June 12 – 10 Stories of The Day!

12 Jun, 2020 | 09:31h | UTC

1 – Widespread mask-wearing could prevent COVID-19 second waves: study – Reuters

Original Study: A modelling framework to assess the likely effectiveness of facemasks in combination with ‘lock-down’ in managing the COVID-19 pandemic – Proceedings of the Royal A

2 – Face Masks Considerably Reduce COVID-19 Cases in Germany: A Synthetic Control Method Approach – Institute of Labor Economics

3 – Covid-19: Appropriate PPE prevents infections in doctors in frontline roles, study shows – The BMJ

Original Study: Use of personal protective equipment against coronavirus disease 2019 by healthcare professionals in Wuhan, China: cross sectional study – The BMJ

4 – Opinion: John Ioannidis and Medical Tribalism in the Era of Covid-19 – Undark

“The critical questions the Stanford professor is raising about Covid-19 have gotten lost amid partisan bickering”

5 – Debate: What to Think of Public Health Experts Defending Protests During the Pandemic?

Opinion 1: Public-Health Experts Are Not Hypocrites – The Atlantic

Opinion 2: We often accuse the right of distorting science. But the left changed the coronavirus narrative overnight – The Guardian

“Health is about more than simply remaining free of coronavirus infection.” (from The Atlantic)

“Progressives blithely accepted throwing millions out of work to fight coronavirus – but now urge street protests to fight racism” (from The Guardian)

6 – Prevalence of Gastrointestinal Symptoms and Fecal Viral Shedding in Patients With Coronavirus Disease 2019: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary: COVID-19 may spread through feces of those infected, analysis finds – UPI

7 – Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Geneva, Switzerland (SEROCoV-POP): a population-based study – The Lancet

8 – Covid-19 Patient Gets Double Lung Transplant, Offering Hope for Others – The New York Times

9 – Rehabilitation after COVID-19: an evidence-based approach – Clinical Medicine Journal

10 –COVID-19 Updates / 12 June 2020 Edition

12 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Thu June 11 – 10 Stories of The Day!

11 Jun, 2020 | 09:54h | UTC

1 – Prone position ventilation in non-intubated, spontaneously ventilating patients: New guidance from the Intensive Care Society (UK) and existing evidence – Journal of the Intensive Care Society

2 – Why, when, and how to use lung ultrasound during the COVID-19 pandemic: enthusiasm and caution – European Heart Journal – Cardiovascular Imaging

3 – Risks to healthcare workers following tracheal intubation of patients with COVID‐19: a prospective international multicentre cohort study – Anaesthesia

4 – The Importance of Proper Death Certification During the COVID-19 Pandemic – JAMA

5 – Asymptomatic coronavirus spread is real – Vox

6 – How and When to End the COVID-19 Lockdown: An Optimization Approach – Frontiers in Public Health

7 – COVID-19 and Cushing’s syndrome: recommendations for a special population with endogenous glucocorticoid excess – The Lancet Diabetes & Endocrinology

8 – Coronavirus Vaccine Tracker – The New York Times

9 – Collective intelligence, not market competition, will deliver the best Covid-19 vaccine – STAT

10 –COVID-19 Updates / 11 June 2020 Edition

11 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Wed June 10 – 10 Stories of The Day!

10 Jun, 2020 | 05:01h | UTC

1 – Three big studies dim hopes that hydroxychloroquine can treat or prevent COVID-19 – Science

Original Studies: No Benefit From the Use of Hydroxychloroquine in Hospitalized Patients with COVID-19 AND Hydroxychloroquine Not Effective as Postexposure Prophylaxis for Covid-19

2 – Managing ICU surge during the COVID-19 crisis: rapid guidelines – Intensive Care Medicine

3 – ‘We don’t actually have that answer yet’: WHO clarifies comments on asymptomatic spread of Covid-19 – STAT

4 – Exercise in the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) era: A Question and Answer session with the experts Endorsed by the section of Sports Cardiology & Exercise of the European Association of Preventive Cardiology (EAPC) – European Journal of Preventive Cardiology

5 – Effects of COVID‐19 Lockdown on Lifestyle Behaviors in Children with Obesity Living in Verona, Italy: A Longitudinal Study – Obesity

Commentary: COVID-19 lockdowns worsen childhood obesity, study finds – University at Buffalo

6 – Psychological Distress and Loneliness Reported by US Adults in 2018 and April 2020 – JAMA

Commentary: Survey finds large increase in psychological distress reported among US adults during the COVID-19 pandemic – Johns Hopkins University Bloomberg School of Public Health AND Three times more Americans are now experiencing psychological distress due to the pandemic -ZME Science

7 – AGA Clinical Practice Guidelines on the Role of Probiotics in the Management of Gastrointestinal Disorders – Gastroenterology

News Release: AGA does not recommend the use of probiotics for most digestive conditions

8 – American Cancer Society Guideline for Diet and Physical Activity for cancer prevention – CA: A Cancer Journal for Clinicians

News Release: American Cancer Society Updates Diet & Physical Activity Guideline for Cancer Prevention

9 – Screening for Anxiety in Adolescent and Adult Women: A Recommendation From the Women’s Preventive Services Initiative – Annals of Internal Medicine

Commentaries: New recommendations for early detection, treatment of unrecognized anxiety disorders in women, adolescent girls – OHSU AND WPSI Advises Screening for Anxiety in Women, Teen Girls – Physician’s Briefing AND Group Recommends Screening Females Aged 13 and Over for Anxiety – NEJM Journal Watch

10 –COVID-19 Updates / 10 June 2020 Edition

10 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Tue June 09 – 10 Stories of The Day!

9 Jun, 2020 | 05:08h | UTC

1 – Study: Lockdowns Prevented or Delayed Millions of Infections

The effect of large-scale anti-contagion policies on the COVID-19 pandemic – Nature

Commentaries: Shutdowns through early April prevented about 60 million US coronavirus infections, study says – CNN AND Coronavirus: Lockdowns in Europe saved millions of lives – BBC AND Lockdowns may have averted 3 million deaths in Europe by curbing COVID-19, study suggests – CBC

2 – Is the world making progress against the pandemic? We built the chart to answer this question – Our World in Data

3 – Editorial: SARS-CoV-2–Related Inflammatory Multisystem Syndrome in Children: Different or Shared Etiology and Pathophysiology as Kawasaki Disease? – JAMA

Study 1: Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2 – JAMA

Study 2: Multisystem Inflammatory Syndrome Related to COVID-19 in Previously Healthy Children and Adolescents in New York City – JAMA

Commentary: Expert reaction to new paper looking at clinical characteristics of 58 children in England hospitals with Kawasaki-like syndrome – Science Media Centre

4 – Assessment and management of adults with asthma during the covid-19 pandemic – The BMJ

5 – Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study – The BMJ

6 – Positive Covid-19 tests kept a mom and baby apart for 55 days. Experts see it as a bigger testing problem – STAT

7 – Symptom Course in COVID-19 Outpatients – medRxiv

Commentary: Symptoms can last for weeks even in mild cases, lockdowns likely saved millions of lives – Reuters

8 – Early Health Technology Assessment for a COVID-19 Vaccine – Center for Global Development

9 – When 511 Epidemiologists Expect to Fly, Hug and Do 18 Other Everyday Activities Again – The New York Times

10 –COVID-19 Updates / 09 June 2020 Edition

09 June 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

Mon June 08 – 10 Stories of The Day!

8 Jun, 2020 | 04:49h | UTC

1 – WHO Now Recommends the Use of Face Masks by the General Public

Advice on the use of masks in the context of COVID-19 – World Health Organization

Media Briefing: WHO Director-General’s opening remarks at the media briefing on COVID-19 – 5 June 2020

Commentaries: The WHO has new guidelines on face masks to fight Covid-19 – Vox AND WHO Urges Demonstrators To Protect Themselves From COVID-19, Issues New Mask Guidelines – Health Policy Watch AND WHO advises public to wear face masks when unable to distance – The Guardian AND Anyone Living in Areas With ‘Widespread’ COVID-19 Transmission Should Wear Masks, WHO Says – TIME

“In light of evolving evidence, WHO advises that governments should encourage the general public to wear masks where there is widespread transmission and physical distancing is difficult, such as on public transport, in shops or in other confined or crowded environments.” (from WHO Director-General’s media briefing)

2 – We can’t be 100% sure face masks work – but that shouldn’t stop us wearing them – The Guardian

3 – Randomized Trial: No Benefit From the Use of Hydroxychloroquine in Hospitalized Patients with COVID-19

Statement from the Chief Investigators of the Recovery Study: No clinical benefit from use of hydroxychloroquine in hospitalised patients with COVID-19

Commentary: Study: Hydroxychloroquine had no benefit for hospitalized Covid-19 patients, possibly closing door to use of drug – STAT

4 – False Negative Tests for SARS-CoV-2 Infection — Challenges and Implications – New England Journal of Medicine

Commentary: New report examines challenges and implications of false-negative COVID-19 tests – The Geisel School of Medicine at Dartmouth

5 – Prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST Guideline and Expert Panel Report – CHEST

6 – Ten things we learned about COVID-19 – Intensive Care Medicine

7 – Caring for Women Who Are Planning a Pregnancy, Pregnant, or Postpartum During the COVID-19 Pandemic – JAMA

8 – Will COVID-19 Kill the Routine Physical Exam? – Scientific American

9 – Extended use or re-use of single-use surgical masks and filtering facepiece respirators: A rapid evidence review – CEBM Oxford

10 –COVID-19 Updates / 08 June 2020 Edition