Pediatrics – Neonatal/Perinatal
RCT: Discontinuing nasal continuous positive airway pressure either at 5 cm H2O vs. 3 cm H2O in infants ≤32 weeks of gestational age
3 May, 2021 | 05:15h | UTCDiscontinuing Nasal Continuous Positive Airway Pressure in Infants ≤32 Weeks of Gestational Age: A Randomized Control Trial – The Journal of Pediatrics (link to abstract – $ for full-text)
Commentary on Twitter
Randomized trial finds stopping CPAP at 5 cm H2O versus weaning until 3 cm H2O & then stopping is no different except babies will less likely to fail the initial attempt of discontinuation in weaning group (wean until 3 cm & then stop)@EBNEO @JPediatr https://t.co/G5yNK3fD1b
— Abdul Razak, MD, FRCPCH (@DrAbdulRazak_MD) October 27, 2020
Cohort study: Association of maternal SARS-CoV-2 infection in pregnancy with neonatal outcomes – “although babies born of test-positive mothers are more likely to be born early, extremely few were infected with COVID-19”
30 Apr, 2021 | 08:17h | UTCAssociation of Maternal SARS-CoV-2 Infection in Pregnancy With Neonatal Outcomes – JAMA
News release: Low risk of infection in babies born to mothers with COVID-19 – Karolinska Institutet
Editorial: Understanding Risk for Newborns Born to SARS-CoV-2–Positive Mothers – JAMA
Commentary on Twitter
Maternal #SARSCoV2 infection in pregnancy was significantly associated with small increases in the absolute risk of respiratory disorders and some other neonatal morbidities https://t.co/ANkXkaxnwp
— JAMA (@JAMA_current) April 29, 2021
Pre-post study: A hospital quality improvement intervention significantly reduced the rates of cesarean delivery for nulliparous, term, singleton, vertex births
29 Apr, 2021 | 08:21h | UTCHospital Quality Improvement Interventions, Statewide Policy Initiatives, and Rates of Cesarean Delivery for Nulliparous, Term, Singleton, Vertex Births in California – JAMA (free for a limited period)
Editorial: Initiatives to Reduce Cesarean Delivery Rates for Low-risk First Births – JAMA
Commentary on Twitter (thread – click for more)
"Rates of cesarean delivery for NTSV births in California decreased [from 26% to 22.8%] in the setting of a coordinated hospital-level collaborative and statewide initiatives designed to support vaginal birth.
"The rest of the US had no change."https://t.co/jwKkQZ4nix @cmqcc
— Ben Harder #BlackLivesMatter (@benharder) April 27, 2021
Covid-19: More data on the increased risks to pregnant women and their newborn infants
23 Apr, 2021 | 08:44h | UTCEditorial: COVID-19 in Pregnant Women and Their Newborn Infants
Commentaries: Pregnant women with COVID-19 face high mortality rate – University of Washington School of Medicine AND Covid-19 raises risks for expectant mothers and babies, study says – CNN
Commentary on Twitter
18 country study in >2000 pregnant women with and without #COVID19 shows higher complication and death rates in symptomatic, but not asymptomatic, women with COVID-19. Their babies were at greater risk of neonatal complications, mainly due to preterm birth https://t.co/mRl8OOIMsz
— JAMA Pediatrics (@JAMAPediatrics) April 22, 2021
Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons
22 Apr, 2021 | 08:49h | UTCAudio Interview: Covid-19 Vaccines and Pregnancy — A Conversation with CDC Director Rochelle Walensky – New England Journal of Medicine
Commentaries: No evidence that Pfizer or Moderna vaccines are unsafe during pregnancy, a preliminary study says. – The New York Times AND Preliminary data show no safety concerns for pregnant women receiving COVID-19 vaccines – AAP News AND Messenger RNA COVID vaccines likely safe for pregnant women: Study – ABC News
Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions
22 Apr, 2021 | 08:19h | UTCSee also: Final Report AND Evidence Summary
NICE Guideline | Neonatal infection: antibiotics for prevention and treatment
21 Apr, 2021 | 06:46h | UTC
NICE Guideline | Postnatal care
21 Apr, 2021 | 06:43h | UTCPostnatal care – National Institute for Health and Care Excellence
Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis
2 Apr, 2021 | 09:23h | UTCCommentaries: Covid-19 led to a global increase in stillbirths, maternal mortality, and depression, review finds – CNN AND COVID-19 pandemic and health-care disruptions: count the most vulnerable – The Lancet Global Health
Commentary on Twitter
NEW—Pregnancy outcomes worsened during the #COVID19 pandemic worldwide, with an increase in maternal deaths, stillbirth, ruptured ectopic pregnancies, and maternal depression.
New review of 40 studies from 17 countries in @LancetGH: https://t.co/GWBohu6b6k pic.twitter.com/4RzgtShYeH
— The Lancet (@TheLancet) April 1, 2021
The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis
31 Mar, 2021 | 03:27h | UTC
Cohort study: Even small amounts of Caffeine consumption in pregnancy were linked to smaller neonatal birth size
28 Mar, 2021 | 22:14h | UTCCommentaries: Even a Little Coffee in Pregnancy Could Impact Newborn’s Weight: Study – HealthDay AND Moderate daily caffeine intake during pregnancy may lead to smaller birth size – NIH News Releases
Commentary on Twitter
Cohort study finds even small amounts of caffeine consumption in pregnancy were associated with smaller birthweight and lean tissue measures, consistent for measured plasma caffeine/paraxanthine, and self-reported caffeine consumption. @NIH https://t.co/YzDVU6ejYO
— JAMA Network Open (@JAMANetworkOpen) March 25, 2021
Systematic review: Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates
18 Mar, 2021 | 08:45h | UTC
WHO: New research highlights risks of separating newborns from mothers during COVID-19 pandemic
17 Mar, 2021 | 03:04h | UTC
M-A: Assessment of postnatal corticosteroids for the prevention of bronchopulmonary dysplasia in preterm neonates
16 Mar, 2021 | 01:38h | UTCAssessment of Postnatal Corticosteroids for the Prevention of Bronchopulmonary Dysplasia in Preterm Neonates: A Systematic Review and Network Meta-analysis – JAMA Pediatrics (free for a limited period)
Editorial: The Swinging Pendulum of Postnatal Corticosteroid Use (free for a limited period)
M-A: Association of umbilical cord management strategies with outcomes of preterm infants
9 Mar, 2021 | 02:26h | UTCAssociation of Umbilical Cord Management Strategies With Outcomes of Preterm Infants: A Systematic Review and Network Meta-analysis – JAMA Pediatrics (free for a limited period)
RCT: Evaluation of oral dextrose gel for prevention of neonatal hypoglycemia
7 Mar, 2021 | 19:01h | UTC
Position Paper: Nutritional management of the critically ill neonate
4 Mar, 2021 | 08:22h | UTC
Cohort study: Association between preterm-birth phenotypes and differential morbidity, growth, and neurodevelopment at age 2 years
2 Mar, 2021 | 01:41h | UTC
M-A: Umbilical cord management at term and late preterm birth
2 Mar, 2021 | 01:25h | UTCUmbilical Cord Management at Term and Late Preterm Birth: A Meta-analysis – Pediatrics (link to abstract – $ for full-text)
Indian Guidelines for pediatric skin care in neonates, infants, and children
28 Feb, 2021 | 20:37h | UTCIndian Academy of Pediatrics Guidelines for Pediatric Skin Care
Prevalence of bicuspid aortic valve and associated aortopathy in newborns in Copenhagen, Denmark
21 Feb, 2021 | 21:58h | UTCPrevalence of Bicuspid Aortic Valve and Associated Aortopathy in Newborns in Copenhagen, Denmark – JAMA (link to abstract – $ for full-text)
Commentary on Twitter
In this population epi study the prevalence of bicuspid aortic valve (BAV) among newborns in Copenhagen was 0.77%; aortopathy incl. coarctation was common, suggesting that it represents a fetal malformation https://t.co/xqUBzQn9NA @HenningBundgaa1 @jamapediatrics
— JAMA (@JAMA_current) February 11, 2021
Meta-analysis: Sustained lung inflations during neonatal resuscitation at birth
19 Feb, 2021 | 02:21h | UTCSustained Lung Inflations During Neonatal Resuscitation at Birth: A Meta-analysis – Pediatrics (link to abstract – $ for full-text)
Commentaries on Twitter
#Metaanalysis by @KapadiaNeo & @Ilcor_org colleagues finds Sustained lung inflation is a potential harmful intervention in babies, particularly in extreme preterm infants who are at increased risk of death@AAPJournals @EBNEO #NeoEBM @wyllie_jonathan https://t.co/rsDYtDRgm0 pic.twitter.com/fO6mu4ICil
— Abdul Razak, MD, FRCPCH (@DrAbdulRazak_MD) December 23, 2020
If your center is still using sustained lung inflations this systematic review should give you reason to pause. #neoEBM #Meded #MedTwitter https://t.co/WCHCdHzyGX pic.twitter.com/53lOMIFQas
— Michael Narvey (@NICU_Musings) January 8, 2021
RCT: Among children with Myelomeningocele, long term results confirm the benefits of prenatal repair compared to standard postnatal repair
10 Feb, 2021 | 01:28h | UTCPrenatal Repair and Physical Functioning Among Children With Myelomeningocele: A Secondary Analysis of a Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)
Editorial: Long-term Outcomes of Children After Fetal Surgery for Spina Bifida—Toward Sustainability – JAMA Pediatrics (free for a limited period)
Commentaries: Spina Bifida Repair: The Sooner the Better – Physician’s Weekly AND Prenatal Myelomeningocele Repair Tied to Better Function – HealthDay
Commentary on Twitter
Previous work reported that prenatal versus postnatal repair of myelomeningocele resulted in improved physical functioning. A secondary analysis at #jamapeds reports that these improvements persist into school age. https://t.co/2aehk5L6pi pic.twitter.com/hASLEUcvqm
— JAMA Pediatrics (@JAMAPediatrics) February 9, 2021
M-A: Interventions to minimize blood loss in very preterm infants
10 Feb, 2021 | 01:19h | UTC
RCT: Enteral lipid supplement reduces the risk of severe retinopathy of prematurity
7 Feb, 2021 | 21:04h | UTCCommentary: Halved risk for severe retinal disease in extremely premature infants – University of Gothenburg
Commentary on Twitter
A new study at #jamapeds reports that enteral fatty acid supplementation with AA and DHA lowers the risk of retinopathy of prematurity among extremely preterm infants. https://t.co/skN41O2YX4 pic.twitter.com/c9bv3V6wbn
— JAMA Pediatrics (@JAMAPediatrics) February 4, 2021