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Artificial sweetener erythritol possibly implicated in increased cardiovascular risk

1 Mar, 2023 | 14:08h | UTC

Summary: A recent study published in Nature Medicine found that erythritol, a popular artificial sweetener, is possibly implicated with an increased risk of major adverse cardiovascular events (MACE) such as heart attack and stroke. Analyzing data from over 4,000 people in the US and Europe, the researchers found that those with higher blood erythritol levels were at a greater risk of MACE. The researchers also examined the effects of adding erythritol to whole blood or isolated platelets and found that it made platelets easier to activate and form clots. In addition, a pilot intervention study with healthy volunteers showed that erythritol ingestion led to a marked and sustained increase in plasma erythritol levels above those associated with heightened platelet reactivity and thrombosis potential. The authors note that further studies are needed to confirm their findings and assess the long-term safety of erythritol.

Article: The artificial sweetener erythritol and cardiovascular event risk – Nature Medicine (free for a limited period)

News Release: Cleveland Clinic study finds common artificial sweetener linked to higher rates of heart attack and stroke

Commentaries:

Zero-calorie sweetener linked to heart attack and stroke, study finds – CNN

Could a Common Sweetener Raise Heart Risks? – HealthDay

 

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