Pediatrics – Allergy and Immunology
Cohort Study: Short-term outcomes of corticosteroid monotherapy in multisystem inflammatory syndrome in children.
30 Mar, 2022 | 10:40h | UTC
Commentary on Twitter
In this study, corticosteroid monotherapy successfully treated a subset of patients with mild multisystem inflammatory syndrome in children. https://t.co/fuhHeBSaRp
— JAMA Pediatrics (@JAMAPediatrics) March 28, 2022
Cohort Study: Prenatal occupational disinfectant exposure linked to increased risk of childhood allergies.
30 Mar, 2022 | 08:48h | UTCCommentary: Disinfectant use by pregnant women may increase risk for asthma and eczema in children – BMJ/News Medical
Commentary on Twitter
Disinfectant use during pregnancy linked to childhood asthma and eczema, suggests @OEM_BMJ research https://t.co/90JYoTFHpo pic.twitter.com/zlqouZWQSM
— BMJ (@bmj_company) March 29, 2022
The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.
28 Mar, 2022 | 09:48h | UTCM-A: Most patients with allergy to Penicillin can be given Cefazolin
Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy
Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule
Consensus Recommendations: Management of a Surgical Patient with a Label of Penicillin Allergy
Practical Guide for Pharmacists to Successfully Implement Penicillin Allergy Skin Testing
NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk
Commentary on Twitter
In this cohort study of more than 330,000 children, less than 5% were labeled with penicillin allergy with wide variation across practices, with 8% of those labeled despite not receiving any penicillin prescription. https://t.co/kvXcm1RKRd
— JAMA Network Open (@JAMANetworkOpen) March 15, 2022
Food protein-induced enterocolitis syndrome: A large French multicentric experience.
25 Mar, 2022 | 08:27h | UTC
Systematic Review: Strategies for using topical corticosteroids in children and adults with eczema.
21 Mar, 2022 | 08:33h | UTCStrategies for using topical corticosteroids in children and adults with eczema – Cochrane Library
Summary: What is the best way to use topical corticosteroids to treat people with eczema? – Cochrane Library
Commentary on Twitter
What is the best way to use topical #corticosteroids to treat people with #eczema?
"Generally, stronger topical corticosteroids are probably more effective than weaker preparations". https://t.co/iaH6fzyXL4Read the latest evidence from @CochraneSkin @CebdNottm pic.twitter.com/f01BO2FyDs
— Cochrane UK (@CochraneUK) March 17, 2022
Retrospective Cohort: Asthma in children and adolescents is not associated with increased risk of SARS-CoV-2 infection.
15 Mar, 2022 | 08:55h | UTCAsthma and the Risk of SARS-CoV-2 Infection Among Children and Adolescents – Pediatrics
Commentary: Kids with asthma not at higher risk of COVID-19, study finds – CIDRAP
Related:
We expected people with asthma to fare worse during COVID. Turns out they’ve had a break.
Asthma in COVID-19 hospitalizations: An overestimated risk factor?
Open Label RCT: Azithromycin for poorly controlled asthma in children.
15 Mar, 2022 | 08:39h | UTCAzithromycin for Poorly Controlled Asthma in Children: A randomized controlled trial – CHEST (link to abstract – $ for full-text)
Commentary: Adding azithromycin to standard care improves asthma control, exacerbations in children – Healio
Systematic Review: Effect of asthma education on health outcomes in children.
25 Feb, 2022 | 11:09h | UTC
Anti-inflammatory treatment of Kawasaki Disease: comparison of current guidelines and perspectives.
25 Feb, 2022 | 10:29h | UTC
ACR Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS–CoV-2 and Hyperinflammation in Pediatric COVID-19.
15 Feb, 2022 | 10:17h | UTCCommentary and summary: ACR Updates Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With COVID – RheumNow
Clinical practice guideline on tympanostomy tubes in children.
10 Feb, 2022 | 10:10h | UTC
Short Review | Hypersensitivity reactions to vaccines in children: from measles to SARS-CoV-2.
2 Feb, 2022 | 08:13h | UTCCommentary: Vaccine hypersensitivity in children – News Medical
RCT: In children with peanut allergy, initiation of peanut oral immunotherapy before age 4 years induced desensitization in 71% of patients and remission in 21%.
24 Jan, 2022 | 08:18h | UTCEfficacy and safety of oral immunotherapy in children aged 1–3 years with peanut allergy (the Immune Tolerance Network IMPACT trial): a randomised placebo-controlled study – The Lancet (link to abstract – $ for full-text)
News Release: Oral immunotherapy induces remission of peanut allergy in some young children – NIH News Releases
Commentary: Peanut Oral Immunotherapy at Younger Age Ups Desensitization in Children – HealthDay
In a study with 1110 children with prolonged fever, MRP8/14 serum levels were validated as a diagnostic marker for systemic juvenile idiopathic arthritis.
14 Jan, 2022 | 08:07h | UTCMRP8/14 serum levels as diagnostic markers for systemic juvenile idiopathic arthritis in children with prolonged fever – Rheumatology (link to abstract – $ for full-text)
Commentary: It is about time: the first validated biomarker for early diagnosis of sJIA – Rheumatology
RCT: Among children between the ages of 6 and 11 years with uncontrolled moderate-to-severe asthma, add-on Dupilumab reduced exacerbations and improved lung function.
9 Dec, 2021 | 10:21h | UTCDupilumab in Children with Uncontrolled Moderate-to-Severe Asthma – New England Journal of Medicine
AAP Clinical Report: Biologics for Asthma and Allergic Skin Diseases in Children.
19 Nov, 2021 | 10:34h | UTCBiologics for Asthma and Allergic Skin Diseases in Children – Pediatrics
An Update on Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2.
11 Nov, 2021 | 08:52h | UTCRelated:
Ten Things to Know About Multisystem Inflammatory Syndrome in Children (MIS-C).
Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.
Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.
Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children
Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)
SR: Multisystem inflammatory syndrome in children related to COVID-19
Ten Things to Know About Multisystem Inflammatory Syndrome in Children (MIS-C).
4 Nov, 2021 | 10:00h | UTCTen Things to Know About MIS-C – American College of Cardiology
Related:
Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.
Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.
Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children
Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)
SR: Multisystem inflammatory syndrome in children related to COVID-19
Podcast: Atopic Dermatitis Pearls.
27 Oct, 2021 | 01:01h | UTCAtopic Dermatitis Pearls – The Cribsiders
Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.
12 Sep, 2021 | 21:54h | UTCCommentary: Outcome Good at One Year for Majority of PIMS-TS Patients – HealthDay
Commentary on Twitter
A new study reports that a small number of pediatric patients are at risk for poor long-term outcomes of multisystem inflammatory syndrome in children. https://t.co/rUk4YEGRin pic.twitter.com/CgBi33Mzd5
— JAMA Pediatrics (@JAMAPediatrics) September 2, 2021
Kids and COVID: why young immune systems are still on top.
7 Sep, 2021 | 21:46h | UTCKids and COVID: why young immune systems are still on top – Nature
Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.
3 Aug, 2021 | 09:05h | UTCSix Month Follow-up of Patients With Multisystem Inflammatory Syndrome in Children – Pediatrics (PDF)
Experts recommend Covid jabs for some under-18s in UK – “advice is that 16 to 18-year-olds can be offered a Pfizer jab if they are in a priority group or live with someone who has a weakened immune system”.
20 Jul, 2021 | 10:15h | UTCCommentaries: Experts recommend Covid jabs for some under-18s in UK – BBC
New Zealand children falling ill in high numbers due to Covid ‘immunity debt’.
14 Jul, 2021 | 11:16h | UTCNew Zealand children falling ill in high numbers due to Covid ‘immunity debt’ – The Guardian
Related: New Zealand, where Covid-19 is dormant, fights another respiratory virus – The New York Times
CDC: mRNA vaccines are likely linked to cases of myocarditis and pericarditis – 1,226 cases of myocarditis or pericarditis have been reported mostly in people under 30.
24 Jun, 2021 | 09:51h | UTCSee also: Experts: mRNA COVID-19 vaccines likely tied to heart inflammation – CIDRAP
Related: Case series: 7 cases of myocarditis following mRNA-based COVID-19 vaccination. AND Case series: clinical and cardiac magnetic resonance imaging findings of 4 cases of myocarditis following mRNA-based COVID-19 vaccination. AND Case series: symptomatic acute myocarditis in 7 adolescents following mRNA COVID-19 vaccination. AND CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. AND Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. AND CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.