Observational study: The combination of Immunoglobulins + Methylprednisolone was associated with a better course of fever compared to Immunoglobulins alone in Multisystem Inflammatory Syndrome in children

Association of Intravenous Immunoglobulins Plus Methylprednisolone vs Immunoglobulins Alone With Course of Fever in Multisystem Inflammatory Syndrome in Children – JAMA

Commentaries on Twitter

In this cohort study, treatment w IVIG + methylprednisolone was associated w lower risk of treatment failure (defined as fever persistence 2d after start of therapy or fever recrudescence within 7 days) vs IVIG alone among children w MIS-C https://t.co/LjEBFuf33q

— JAMA (@JAMA_current) February 1, 2021

Yes, retrospective, but I find these data interesting as I expect the combined treatment group to be the sicker of the 2

Association of IVIG Plus Methylprednisolone With Persistent or Recurrent Fever in Children With MIS-C https://t.co/Oio8t05zQ1 via @JAMA_current @JAMANetwork

— Joshua Denson MD (@jdensonMD) February 2, 2021