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Oncology – Breast

RCT: Heart-protecting drugs likely unnecessary for most breast cancer patients undergoing adjuvant treatment.

8 Jun, 2021 | 09:15h | UTC

Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy (PRADA) Extended Follow-Up of a 2×2 Factorial, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Candesartan and Metoprolol – Circulation

Commentaries: Heart-protecting drugs likely unnecessary for many breast cancer patients – American College of Cardiology

 


Population-based cohort study suggests increased survival after breast conservation surgery + radiotherapy compared to mastectomy with or without radiotherapy in women with breast cancer.

10 May, 2021 | 00:42h | UTC

Survival After Breast Conservation vs Mastectomy Adjusted for Comorbidity and Socioeconomic Status: A Swedish National 6-Year Follow-up of 48 986 Women – JAMA Surgery

Commentary: Breast-Conserving Surgery+RT Yields Significant Survival Benefits For Early-Stage Breast Cancer – Physician’s Weekly

 

Commentary on Twitter

 


AHA Scientific Statement: Close monitoring for heart risk needed if breast, prostate cancer treatment includes hormonal therapies

29 Apr, 2021 | 08:33h | UTC

Impact of Hormonal Therapies for Treatment of Hormone-Dependent Cancers (Breast and Prostate) on the Cardiovascular System: Effects and Modifications: A Scientific Statement From the American Heart Association – Circulation: Genomic and Precision Medicine

News release: Close monitoring for heart risk needed if breast, prostate cancer treatment includes hormones – American Heart Association

Top Things to Know: Impact of Hormonal Therapies for Treatment of Hormone-Dependent Cancers (Breast and Prostate) on the Cardiovascular System – American Heart Association

Commentaries: Hormonal Therapy for Breast and Prostate Cancer: Lessons and Opportunities – American Heart Association AND Hormonal Based Therapies in the Treatment of Breast and Prostate Cancer – balancing the risks! – American Heart Association AND Hormone Cancer Therapies Increase CV Risk: AHA Scientific Statement – TCTMD AND Closely Monitor Heart Health in Cancer Patients Who Get Hormonal Therapies: AHA – HealthDay

 


Systematic Review: PARP (Poly ADP‐Ribose Polymerase) inhibitors for locally advanced or metastatic breast cancer

23 Apr, 2021 | 08:16h | UTC

PARP (Poly ADP‐Ribose Polymerase) inhibitors for locally advanced or metastatic breast cancer – Cochrane Library

Summary: PARP inhibitors for locally advanced or metastatic breast cancer – Cochrane Library

 


RCT: Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer

22 Apr, 2021 | 08:15h | UTC

Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

 


Guide to enhanced recovery for cancer patients undergoing breast surgery and reconstruction

14 Mar, 2021 | 20:01h | UTC

Guide to Enhanced Recovery for Cancer Patients Undergoing Breast Surgery and Reconstruction – Annals of Surgical Oncology

Related: Consensus Review of Optimal Perioperative Care in Breast Reconstruction: Enhanced Recovery after Surgery (ERAS) Society Recommendations – Plastic and Reconstructive Surgery

 


70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age

14 Mar, 2021 | 20:07h | UTC

70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age – The Lancet Oncology (link to abstract – $ for full-text)

 


Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance

5 Mar, 2021 | 08:35h | UTC

Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance – The BMJ

Recommendations: Pharmacovigilance Evidence Review: The effect of COVID-19 vaccines on breast screening – Drug Safety Research Unit

Related: 2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients

 


2 Case Series and Guidance| Lymphadenopathy in COVID-19 Vaccine Recipients

28 Feb, 2021 | 21:42h | UTC

Case series: Lymphadenopathy in COVID-19 Vaccine Recipients: Diagnostic Dilemma in Oncology Patients – Radiology

Related case series in women without cancer: Coronavirus Disease (COVID-19) Vaccination Associated Axillary Adenopathy: Imaging Findings and Follow-Up Recommendations in 23 Women – American Journal of Roentgenology

Related guidance 1: Multidisciplinary Recommendations Regarding Post-Vaccine Adenopathy and Radiologic Imaging: Radiology Scientific Expert Panel – Radiology

Related guidance 2: Mitigating the Impact of Coronavirus Disease (COVID-19) Vaccinations on Patients Undergoing Breast Imaging Examinations: A Pragmatic Approach – American Journal of Roentgenology AND Commentary: What to do when a mammogram shows swollen lymph nodes in women just vaccinated for COVID – Massachusetts General Hospital

Commentary: COVID-19 vaccine affects imaging results, researchers warn – AuntMinnie (free registration required)

 


Clinical practice guidelines for BRCA1 and BRCA2 genetic testing

21 Feb, 2021 | 21:43h | UTC

Clinical practice guidelines for BRCA1 and BRCA2 genetic testing – European Journal of Cancer

 

Commentary on Twitter

 


Review: Optimal supportive care for patients with metastatic breast cancer according to their disease progression phase

18 Feb, 2021 | 02:35h | UTC

Optimal Supportive Care for Patients With Metastatic Breast Cancer According to Their Disease Progression Phase – JCO Oncology Practice

 


Review: Breast cancer in adolescent and young adult women under the age of 40 years

17 Feb, 2021 | 01:13h | UTC

Breast Cancer in Adolescent and Young Adult Women Under the Age of 40 Years – JCO Oncology Practice

 


Cost-effective analysis suggests incorporating baseline breast density at 40 years to determine the frequency of screening in women at average risk for breast cancer

10 Feb, 2021 | 01:37h | UTC

Incorporating Baseline Breast Density When Screening Women at Average Risk for Breast Cancer: A Cost-Effectiveness Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Screening based on breast density at age 40 may reduce breast cancer mortality – ACP Internist AND Screening strategy based on baseline breast density at age 40 may be effective for reducing breast cancer mortality – American College of Physicians AND For Mammography: Baseline at 40 Makes Sense – Diagnostic Imaging

 

Commentary on Twitter

 


PET imaging reveals which breast cancer patients won’t respond to hormone therapy

10 Feb, 2021 | 01:09h | UTC

PET Imaging Reveals Which Breast Cancer Patients Won’t Respond to Hormone Therapy – Diagnostic Imaging

Original study: Association of PET-based estradiol-challenge test for breast cancer progesterone receptors with response to endocrine therapy – Nature Communications

 


Breast Cancer Risk Genes — Association Analysis in More than 113,000 Women

10 Feb, 2021 | 01:07h | UTC

Breast Cancer Risk Genes — Association Analysis in More than 113,000 Women – New England Journal of Medicine

Commentary: Protein-Truncating and Rare Missense Variants in Breast Cancer Risk Genes: Association With Disease Risk – The ASCO Post

 


A population-based study of genes previously implicated in breast cancer

10 Feb, 2021 | 01:05h | UTC

A Population-Based Study of Genes Previously Implicated in Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

 


Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

7 Feb, 2021 | 20:47h | UTC

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries – CA: A Cancer Journal for Clinicians

Commentaries: Breast cancer tops lung cancer as most diagnosed cancer in the world, new report says – CNN AND Breast Cancer Tops Lung Cancer for No. 1 Diagnosis Worldwide – Diagnostic Imaging

Related: Breast cancer now most common form of cancer: WHO taking action – World Health Organization

 

Commentary on Twitter

 


COVID-19 vaccine-linked adenopathies could mimic breast malignancies

2 Feb, 2021 | 01:17h | UTC

COVID-19 Vaccine-Linked Adenopathies Could Mimic Breast Malignancies – Diagnostic Imaging

Original Study: Unilateral axillary Adenopathy in the setting of COVID-19 vaccine – Clinical Imaging

 

Commentaries on Twitter

 


ASCO Guideline: Neoadjuvant chemotherapy, endocrine therapy, and targeted therapy for breast cancer

1 Feb, 2021 | 01:34h | UTC

Neoadjuvant Chemotherapy, Endocrine Therapy, and Targeted Therapy for Breast Cancer: ASCO Guideline – Journal of Clinical Oncology

 


Consensus statement recommends individualizing surveillance mammography for older patients after treatment for early-stage breast cancer

1 Feb, 2021 | 01:33h | UTC

Individualizing Surveillance Mammography for Older Patients After Treatment for Early-Stage Breast Cancer: Multidisciplinary Expert Panel and International Society of Geriatric Oncology Consensus Statement – JAMA Oncology

Commentaries: First Mammography Guidelines Released for Older Breast Cancer Survivors – Diagnostic Imaging AND New Surveillance Mammography Screening Guidelines Issued for Breast Cancer Survivors Aged 75 and Older – The ASCO Post

 


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