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Antibiotic Stewardship

Review: Management of infectious emergencies for the inpatient dermatologist.

17 Oct, 2021 | 21:06h | UTC

Management of Infectious Emergencies for the Inpatient Dermatologist – Current Dermatology Reports (if this link is paywalled, try this one)

 


Review: Timing of antibiotic therapy in the ICU.

17 Oct, 2021 | 21:05h | UTC

Timing of antibiotic therapy in the ICU – Critical Care

 


Cluster RCT: An antimicrobial stewardship intervention safely reduced the use of broad-spectrum antibiotics among patients hospitalized with moderately severe community-acquired pneumonia.

11 Oct, 2021 | 23:55h | UTC

Narrow-spectrum antibiotics for community-acquired pneumonia in Dutch adults (CAP-PACT): a cross-sectional, stepped-wedge, cluster-randomised, non-inferiority, antimicrobial stewardship intervention trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)

 


U.S. Data: Drug-resistant Infections led to $1.9 billion in health care costs, more than 10,000 deaths among older adults in one year.

8 Oct, 2021 | 10:11h | UTC

News release: Drug-resistant Infections Led to $1.9 Billion in Health Care Costs, More Than 10,000 Deaths Among Older Adults in One Year – Infectious Diseases Society of America

Original study: Mortality, Length of Stay, and Healthcare Costs Associated With Multidrug-Resistant Bacterial Infections Among Elderly Hospitalized Patients in the United States – Clinical Infectious Diseases

Commentaries:

Urgent, Comprehensive Federal Action Needed To Stem Mortality and Medicare Costs Associated With Antimicrobial Resistance – Clinical Infectious Diseases

Study highlights impact of antibiotic resistance on older Americans – CIDRAP

 


RCT: Immediate drainage did not improve outcomes compared to postponed intervention in patients with infected necrotizing pancreatitis.

7 Oct, 2021 | 10:35h | UTC

Immediate versus Postponed Intervention for Infected Necrotizing Pancreatitis – New England Journal of Medicine

 


Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.

3 Oct, 2021 | 22:41h | UTC

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021 – Intensive Care Medicine

 


WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections.

1 Oct, 2021 | 10:24h | UTC

WSES/GAIS/SIS-E/WSIS/AAST global clinical pathways for patients with intra-abdominal infections – World Journal of Emergency Surgery

Related:

The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection – Surgical Infections

The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections – World Journal of Emergency Surgery

 


RCT: Doxycycline better than Azithromycin for the treatment of rectal Chlamydia in men who have sex with men.

1 Oct, 2021 | 10:09h | UTC

Doxycycline Versus Azithromycin for the Treatment of Rectal Chlamydia in Men Who Have Sex With Men: A Randomized Controlled Trial – Clinical Infectious Diseases

Related: RCT: Doxycycline for 7 days superior to single-dose azithromycin for the treatment of rectal chlamydia infection.

 


Optimizing antimicrobial use in humans – review of current evidence and an interdisciplinary consensus on key priorities for research.

30 Sep, 2021 | 10:05h | UTC

Optimising antimicrobial use in humans – review of current evidence and an interdisciplinary consensus on key priorities for research – The Lancet Regional Health – Europe

 


M-A: Efficacy and secondary infection risk of tocilizumab, sarilumab and anakinra in COVID-19 patients.

29 Sep, 2021 | 10:24h | UTC

Efficacy and secondary infection risk of tocilizumab, sarilumab and anakinra in COVID-19 patients: A systematic review and meta-analysis – Reviews in Medical Virology

 


Podcast: Neutropenic Fever.

28 Sep, 2021 | 08:52h | UTC

#288 LIVE! Neutropenic Fever featuring Dr. Susan Seo – The Curbsiders

 


Antibiotic Overuse and Stewardship at Hospital Discharge: The Reducing Overuse of Antibiotics at Discharge (ROAD) Home Framework.

26 Sep, 2021 | 21:40h | UTC

Antibiotic Overuse and Stewardship at Hospital Discharge: The Reducing Overuse of Antibiotics at Discharge (ROAD) Home Framework – Clinical Infectious Diseases

 

Commentary on Twitter

 


Less common bacterial, fungal and viral infections: review of management in the pregnant patient.

26 Sep, 2021 | 21:38h | UTC

Less common bacterial, fungal and viral infections: review of management in the pregnant patient – Drugs in Context

 


RCT confirms antibiotics are not needed for most children with uncomplicated lower respiratory tract infection if pneumonia is not suspected clinically.

24 Sep, 2021 | 09:00h | UTC

Antibiotics for lower respiratory tract infection in children presenting in primary care in England (ARTIC PC): a double-blind, randomised, placebo-controlled trial – The Lancet

 

Commentary on Twitter

 


WHO global antimicrobial resistance surveillance for Neisseria gonorrhoeae 2017–18 – In many countries, ciprofloxacin resistance was exceedingly high, and decreased susceptibility or resistance to ceftriaxone and cefixime continued to emerge.

24 Sep, 2021 | 08:53h | UTC

WHO global antimicrobial resistance surveillance for Neisseria gonorrhoeae 2017–18: a retrospective observational study – The Lancet Microbe

 


RCT: Probiotics do not reduce the incidence of ventilator-associated pneumonia in critically ill patients.

22 Sep, 2021 | 10:03h | UTC

Effect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: Probiotic Flops for Ventilator-Associated Pneumonia Prevention – MedPage Today (free registration required)

 


Cluster RCT: Procalcitonin point-of-care testing may reduce antibiotic prescription for patients with suspected lower respiratory tract infection in primary care.

22 Sep, 2021 | 10:01h | UTC

Procalcitonin and lung ultrasonography point-of-care testing to determine antibiotic prescription in patients with lower respiratory tract infection in primary care: pragmatic cluster randomised trial – The BMJ

 


Cluster RCT: Implementing C reactive protein point-of-care testing in nursing homes may reduce antibiotic prescribing for suspected lower respiratory tract infections.

22 Sep, 2021 | 10:02h | UTC

Effect of C reactive protein point-of-care testing on antibiotic prescribing for lower respiratory tract infections in nursing home residents: cluster randomised controlled trial – The BMJ

 


Large cohort study suggests routine replacement (every 96 hours) of peripheral intravenous catheters may reduce the risk of bloodstream infections compared to clinically indicated replacement.

19 Sep, 2021 | 23:34h | UTC

Comparison of Routine Replacement With Clinically Indicated Replacement of Peripheral Intravenous Catheters – JAMA Internal Medicine (free for a limited period)

Related Cochrane Review with different findings: Systematic Review: Clinically‐indicated vs. Routine Replacement of Peripheral Venous Catheters

 

Commentary on Twitter

 


As Covid Cases Rise, So Do Hospital-Related Infections.

17 Sep, 2021 | 10:08h | UTC

As Covid Cases Rise, So Do Hospital-Related Infections – Wired

 


A guide to the treatment of cellulitis and other soft-tissue infections.

16 Sep, 2021 | 09:47h | UTC

A guide to the Tx of cellulitis and other soft-tissue infections – Journal of Family Practice

 


Antifungal Susceptibility Testing: A Primer for Clinicians.

14 Sep, 2021 | 08:46h | UTC

Antifungal Susceptibility Testing: A Primer for Clinicians – Open Forum Infectious Diseases

 

Commentary on Twitter

 


RCT: A Seven-days course of antibiotics for the treatment of bloodstream infections by Enterobacterales was noninferior to a 14-days course.

9 Sep, 2021 | 09:03h | UTC

Seven versus 14-days course of antibiotics for the treatment of bloodstream infections by Enterobacterales. A randomized, controlled trial – Clinical Microbiology and Infection

 

Commentary on Twitter

 


Antibiotics use is linked to increased risk of subsequent colorectal cancer.

7 Sep, 2021 | 21:25h | UTC

Antibiotics Use and Subsequent Risk of Colorectal Cancer: A Swedish Nationwide Population-Based Study – JNCI: Journal of the National Cancer Institute

Commentaries:

Antibiotics linked to increased risk of colon cancer – Umea University

Study links antibiotics use and increased subsequent risk of colorectal cancer – MedicalResearch.com

 


Annual Update in Intensive Care and Emergency Medicine 2021 – Covid articles.

7 Sep, 2021 | 10:50h | UTC

Secondary infections in critically ill patients with COVID-19

Tracheostomy for COVID-19: evolving best practice

See also: Non-Covid articles

 


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