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Urology

#ASCO2017 – Abiraterone for Prostate Cancer

5 Jun, 2017 | 14:51h | UTC

#ASCO2017 – Abiraterone for Prostate Cancer

Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer – New England Journal of Medicine (free) AND Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy – New England Journal of Medicine (free)

ASCO News Releases: Abiraterone Delays Metastatic Prostate Cancer Growth by 18 Months, Extends Survival (free) Abiraterone Slows Advanced Prostate Cancer, Helps Patients Live Longer (free)

 


American Urological Assn. Adds 5 More Unnecessary Practices to Choosing Wisely

23 May, 2017 | 14:24h | UTC

American Urological Assn. Adds 5 More Unnecessary Practices to Choosing Wisely – Physician’s First Watch (free)

See also: Complete American Urological Association list with 15 Things Physicians and Patients Should Question – Choosing Wisely (free)

 


Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline

11 May, 2017 | 18:35h | UTC

Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline (free)

Source: Urologic Groups Offer New Prostate Cancer Management Guideline – Physician’s First Watch (free)

 


Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017

5 May, 2017 | 20:29h | UTC

Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery (free) (RT @jankluytmans and @CIDRAP_ASP see Tweet)

Invited commentary: Surgical Site Infection Prevention – What We Know and What We Do Not Know – JAMA Surgery (free)

Commentary: ‘Long-Awaited’ CDC Guidelines on SSI Prevention Released – Medscape (free registration required)

Related: Global guidelines on the prevention of surgical site infection 2016 – World Health Organization (free)

 


Trial of Transplantation of HCV-Infected Kidneys into Uninfected Recipients

5 May, 2017 | 20:19h | UTC

Correspondence: Trial of Transplantation of HCV-Infected Kidneys into Uninfected Recipients – The New England Journal of Medicine (free)

Transplantation of HCV-infected-kidneys into uninfected recipients seems feasible in this era of direct-acting antiviral agents, maybe shortening waiting times for those willing to take the risk.

 


Urinary catheter care: what does the evidence say?

4 May, 2017 | 20:12h | UTC

Urinary catheter care: what does the evidence say? – Cochrane Library (free)

“How frequently should indwelling urinary catheters be changed? Are catheter washouts effective? Which type of catheter reduces rates of urinary tract infection?”. This post look at the evidence regarding urinary catheter care.

 


ASCO Guideline on Castrate-Resistant Prostate Cancer

3 May, 2017 | 17:23h | UTC

Second-Line Hormonal Therapy for Men With Chemotherapy-Naïve, Castration-Resistant Prostate Cancer: American Society of Clinical Oncology Provisional Clinical Opinion (free)

Source: ASCO Issues Guideline on Castrate-Resistant Prostate Cancer – Medscape (free registration required)

 


Approaches for Evaluation of Asymptomatic Microscopic Hematuria

20 Apr, 2017 | 14:27h | UTC

Cost-effectiveness of Common Diagnostic Approaches for Evaluation of Asymptomatic Microscopic Hematuria – JAMA Internal Medicine (free)

Invited commentary: Asymptomatic Microscopic Hematuria – Rethinking the Diagnostic Algorithm (free)

Routine urinalysis for screening is not presently recommended by any major health organization, but asymptomatic microscopic hematuria is a common incidental finding. This study suggests that the combination of renal ultrasound and cystoscopy is the most cost-effective approach for the evaluation of these patients.

 


Mortality Trends After Surgical Safety Checklist

20 Apr, 2017 | 14:31h | UTC

Mortality Trends After a Voluntary Checklist-based Surgical Safety Collaborative – Annals of Surgery (link to abstract – free PDF available)

Sources: Global Health NOW Newsletter (free) AND South Carolina Hospitals Saw Surgery Deaths Drop After Implementing WHO Checklist – AJMC News (free) AND A simple checklist prevents deaths after surgery, a large new study suggests – The Washington Post (a few articles per month are free)

See also: WHO Surgical Safety Checklist – World Health Organization (free) AND A Surgical Safety Checklist to Reduce Morbidity and Mortality in a Global Population – New England Journal of Medicine (free)

 


European Association of Urology releases its 1st thromboprophylaxis guideline

14 Apr, 2017 | 16:10h | UTC

European Association of Urology releases its 1st thromboprophylaxis guideline (free)

 

Procedure-specific Risks of Thrombosis and Bleeding in Urological Cancer Surgery: Systematic Review and Meta-analysis – European Urology (free)

“Extended thromboprophylaxis is warranted in some procedures (eg, open and robotic cystectomy) but not others (eg, robotic prostatectomy without pelvic lymph node dissection in low-risk patients)

 

Procedure-specific Risks of Thrombosis and Bleeding in Urological Non-cancer Surgery: Systematic Review and Meta-analysis – European Urology (free)

“Extended prophylaxis is warranted for some procedures (eg, kidney transplantation procedures in high-risk patients) but not others (transurethral resection of the prostate and reconstructive female pelvic surgery in low-risk patients)”

 


Prostate Cancer Screening – Conflicting views on the new USPSTF draft recommendations

13 Apr, 2017 | 16:06h | UTC

Prostate Cancer Screening – Conflicting views on the new USPSTF draft recommendations

In favor of screening: New Official Prostate Cancer Screening Guidelines Announced: Too Little, Too Late? – Forbes (free) AND Federal Task Force Softens Opposition To Routine Prostate Cancer Screening – NPR

Against screening: The new recommendations for prostate cancer screenings are a bad deal – STAT News (free)

See also: Original USPSTF draft recommendations and related commentaries in yesterday’s issue

 


Prostate Cancer Screening Draft Recommendations – USPSTF

12 Apr, 2017 | 15:58h | UTC

Prostate Cancer Screening Draft Recommendations – U.S. Preventive Services Task Force (free)

Viewpoint: The US Preventive Services Task Force 2017 Draft Recommendation Statement on Screening for Prostate Cancer: An Invitation to Review and Comment – JAMA (free)

See also: Should you get screened for prostate cancer? We break down the latest advice – STAT News (free)

For those aged 55 to 69 it recommends “informed, individualized decision making based on a man’s values and preferences”. According to a useful infographic from the draft recommendations, the benefits are likely small. For every 1000 men offered PSA based screening over a period of 10-15 years, the test would avoid cancer spreading in 3 men and death from prostate cancer in 1-2 men, with the undesired consequences of false positives and subsequent procedures in many patients.

 


Management of cystic renal lesions

5 Apr, 2017 | 21:51h | UTC

CUA guideline on the management of cystic renal lesions – Canadian Urological Association Journal (free)

 


American College of Radiology (ACR) Appropriateness Criteria Adds Topics

4 Apr, 2017 | 21:19h | UTC

ACR Appropriateness Criteria Adds Topics, Covers More Clinical Variants Than Ever Before (free)

Browse Appropriateness Criteria Topics (free)

Source: Newswise

This comprehensive guide from American College of Radiology (ACR) covers 230 topics with more than 1,100 clinical indications and has just been updated. It is a very useful resource for doctors in all specialties to guide which exam is most appropriate in each clinical situation.

 


Erectile dysfunction in men exposed to the 5α-reductase inhibitors

30 Mar, 2017 | 17:25h | UTC

Persistent erectile dysfunction in men exposed to the 5α-reductase inhibitors, finasteride, or dutasteride – PeerJ (free)

Source: SciCombinator

Observational data suggests there might be a link.

 


Surgeries are being performed with the patient awake

27 Mar, 2017 | 00:59h | UTC

Going Under the Knife, With Eyes and Ears Wide Open – New York Times (free access to 10 articles per month)

“More and more surgeries are being performed with the patient awake and looking on, for financial and medical reasons”.

 


Adverse Effects of Prostate Cancer Treatments

27 Mar, 2017 | 00:48h | UTC

Adverse Effects of Prostate Cancer Treatments Vary – MedPage Today (free registration required)

Study 1 – Link to abstract ($ required for full-text): Association Between Radiation Therapy, Surgery, or Observation for Localized Prostate Cancer and Patient-Reported Outcomes After 3 Years – JAMA

Study 2 – Link to abstract ($ required for full-text): Association Between Choice of Radical Prostatectomy, External Beam Radiotherapy, Brachytherapy, or Active Surveillance and Patient-Reported Quality of Life Among Men With Localized Prostate Cancer – JAMA

 


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