M-A: New pharmacologic agents (Ditans and Gepants) are not as good as triptans for treating migraines.

Comparison of New Pharmacologic Agents With Triptans for Treatment of Migraine: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary: Migraine: Older Drugs May Be Best Bet for Lessening Pain – Physician’s Weekly

Commentary on Twitter

This systematic review and meta-analysis found that ditans and gepants were associated with less efficacy compared with triptans, whereas gepants were associated with fewer adverse events compared with triptans for migraine treatment. https://t.co/PFCHg4MZ8r

— JAMA Network Open (@JAMANetworkOpen) October 11, 2021