Neurology | Page 32 of 81 | Links Medicus Content Curation & Alerts in Medicine

Three Neurologic Societies, Including the AAN, Issue Strong Position Statement on Aducanumab.

24 Nov, 2021 | 08:36h | UTC

Three Neurologic Societies, Including the AAN, Issue Strong Position Statement on Aducanumab – Neurology Today

See statement: Decisions With Patients and Families Regarding Aducanumab in Alzheimer Disease, With Recommendations for Consent: AAN Position Statement – Neurology

Editorial: Aducanumab for Alzheimer’s disease?

FDA approvement of Alzheimer’s drug sparks controversy among doctors.

Commentary on Twitter

Decisions With Patients and Families Regarding #Aducanumab in Alzheimer Disease, With Recommendations for Consent—Read the full AAN @AANMember Position Statement: https://t.co/ckoIVRi4DE #Neurology pic.twitter.com/q8TSU67zm9

— Neurology Journal (@GreenJournal) November 19, 2021

Systematic Review: Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery.

24 Nov, 2021 | 08:22h | UTC

Summary: Selective serotonin reuptake inhibitors for stroke recovery – Cochrane Library

Original Article: Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery – Cochrane Library

RCT: Routine treatment with fluoxetine does not reduce the incidence of depression after stroke.

[Abstract Only] Randomized trial: Fluoxetine does not improve functional recovery after acute stroke

Randomized Trial: Effects of Fluoxetine on Functional Outcomes After Acute Stroke

Commentary on Twitter

Selective #serotonin reuptake inhibitors for #stroke recovery https://t.co/7R5bijz49e Updated @CochraneStroke systematic review: 'reduced risk of future depression by about a quarter, but led to a slight increase in the risk of seizures & increased the risk of bone fractures.'

— The Cochrane Library (@CochraneLibrary) November 19, 2021

M-A: Current evidence does not support intensive blood pressure reduction as a preventive strategy for cognitive decline and dementia.

23 Nov, 2021 | 08:26h | UTC

Evaluation of Intensive vs Standard Blood Pressure Reduction and Association With Cognitive Decline and Dementia: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary on Twitter

Meta-analysis found no associated reduction in the risk of cognitive decline with intensive as compared to standard blood pressure (BP) interventions. There is insufficient evidence to support intensive BP management to prevent cognitive impairment. https://t.co/2BEV1ywrCO

— JAMA Network Open (@JAMANetworkOpen) November 22, 2021

Review: Counting the neurological cost of COVID-19.

19 Nov, 2021 | 10:52h | UTC

Counting the neurological cost of COVID-19 – Nature Reviews Neurology

Commentary on Twitter

In our latest News & Views, Abdul Mannan Baig discusses how the neurological manifestations of COVID-19 are expected to increase the burden of morbidity and mortality. #NewfromNRNeurology https://t.co/DNc6B1OBpM

— Nat Rev Neurology (@NatRevNeurol) November 18, 2021

What is the functional/organic distinction actually doing in psychiatry and neurology?

19 Nov, 2021 | 10:29h | UTC

What is the functional/organic distinction actually doing in psychiatry and neurology? – Wellcome Open Research

Commentary on Twitter

Beautiful paper puts nails in coffin of outdated/inaccurate distinction "Functional" Vs "Organic".

Confusion causes great harms:
I've seen many 100s patients mislabeled primary psych disorder whose symptoms were really caused by medical illness/med side effect/drugs.

Must read: https://t.co/Fl492ADrjE

— Allen Frances (@AllenFrancesMD) November 12, 2021

Observational study in patients with stroke with large-vessel occlusion presenting in the extended window suggests non-contrast CT is as good as CT perfusion or MRI to select patients for thrombectomy.

18 Nov, 2021 | 08:41h | UTC

Noncontrast Computed Tomography vs Computed Tomography Perfusion or Magnetic Resonance Imaging Selection in Late Presentation of Stroke With Large-Vessel Occlusion – JAMA Neurology

Commentary: Noncontrast CT a cost-friendly alternative to select late-stroke patients for thrombectomy – Health Imaging

Commentary on Twitter

Don’t have CTP worry not! No MRI/MRP worry not! Good old non-contrast CTH performs just as well for pt selection! But I do like those colored CBF, CBV, MTT maps & don’t like the errors in image processing! This will inc access to late thrombectomy #NoELVOleftbehind @almuftifawaz https://t.co/vBv5y2IDjT

— Neha Dangayach MD MSCR FAAN FANA FCCP FCCM FNCS (@drdangayach) November 11, 2021

M-A: In patients with anterior circulation acute stroke and evidence of reversible cerebral ischemia across the 6–24 h time window, thrombectomy was associated with higher rates of independence in activities of daily living at 90 days than best medical therapy alone.

18 Nov, 2021 | 08:43h | UTC

Thrombectomy for anterior circulation stroke beyond 6 h from time last known well (AURORA): a systematic review and individual patient data meta-analysis – The Lancet (link to abstract – $ for full-text)

Demystifying the EEG report for intensivists.

18 Nov, 2021 | 08:36h | UTC

Demystifying the EEG Report – NeuroEMCrit

AAN Guideline: Dopaminergic Therapy for Motor Symptoms in Early Parkinson Disease.

17 Nov, 2021 | 08:32h | UTC

Dopaminergic Therapy for Motor Symptoms in Early Parkinson Disease Practice Guideline Summary – Neurology

News Release: AAN Issues Guideline for Treatment of Early Parkinson’s Disease – American Academy of Neurology

Drug-induced orthostatic hypotension: A systematic review and meta-analysis of randomized controlled trials.

17 Nov, 2021 | 08:12h | UTC

Drug-induced orthostatic hypotension: A systematic review and meta-analysis of randomised controlled trials – PLOS Medicine

#AHA21 – [News release – not published yet] RCT: Long-term, low-dose aspirin did not affect risk of dementia in adults with type 2 diabetes.

16 Nov, 2021 | 08:30h | UTC

Long-term, low-dose aspirin did not affect risk of dementia in adults with type 2 diabetes – American Heart Association

Original Study: Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes

RCT: In patients with acute stroke eligible for intravenous alteplase and endovascular treatment, intravenous alteplase before endovascular treatment did not improve outcomes compared to endovascular treatment alone.

11 Nov, 2021 | 08:43h | UTC

A Randomized Trial of Intravenous Alteplase before Endovascular Treatment for Stroke – New England Journal of Medicine (link to abstract – $ for full-text)

A New Dementia Test Raises More Questions Than Answers – “A 5-minute assessment on an iPad could transform how we screen for dementia—or overwhelm the health care system with worried test-takers”.

11 Nov, 2021 | 08:29h | UTC

A New Dementia Test Raises More Questions Than Answers – Wired

Systematic Review: Prevention of dementia and decline in cognition by using multi-domain interventions.

11 Nov, 2021 | 08:27h | UTC

Summary: Prevention of dementia and decline in cognition by using multi-domain interventions – Cochrane Library

Original Study: Multi‐domain interventions for the prevention of dementia and cognitive decline – Cochrane Library

Guideline: Nonpharmacological treatment of persistent postconcussion symptoms in adults.

10 Nov, 2021 | 07:07h | UTC

Nonpharmacological Treatment of Persistent Postconcussion Symptoms in Adults: A Systematic Review and Meta-analysis and Guideline Recommendation – JAMA Network Open

Invited commentary: Advances in Clinical Management of Persistent Postconcussion Symptoms—The Danish National Clinical Guideline – JAMA Network Open

Commentary on Twitter

Based on low certainty of evidence or based on consensus, new guideline provides recommendations for commonly applied non-pharmacological interventions to treat persistent post-concussion symptoms in adults. https://t.co/CM1pbMqRXN

— JAMA Network Open (@JAMANetworkOpen) November 9, 2021

M-A: Among patients with acute intracerebral hemorrhage, interventions to lower blood pressure within 7 days of the onset had no overall benefit on functional recovery, despite reducing bleeding.

10 Nov, 2021 | 06:55h | UTC

Early lowering of blood pressure after acute intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data – Journal of Neurology, Neurosurgery & Psychiatry

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain.

9 Nov, 2021 | 01:17h | UTC

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Things We Do for No Reason: Prescribing Tramadol for Inpatients in Pain.

5 Nov, 2021 | 09:44h | UTC

Things We Do for No Reason: Prescribing Tramadol for Inpatients in Pain – Journal of Hospital Medicine

Large observational study suggests Tramadol is associated with increased risk of adverse outcomes compared to Codeine.

Tramadol: Where do we go from here? – “Tramadol’s unpredictability, unique potential harms, and lack of advantage over other opioids or NSAIDs are now well recognized”.

Cohort Study: Chronic Use of Tramadol After Acute Pain Episode

J&J Covid-19 vaccination is associated with increased risk of cerebral venous sinus thrombosis.

2 Nov, 2021 | 03:02h | UTC

Age- and Sex-Specific Incidence of Cerebral Venous Sinus Thrombosis Associated With Ad26.COV2.S COVID-19 Vaccination – JAMA

Commentary: Cerebral Venous Sinus Thrombosis Rate Up After Ad26.COV2.S Shot – HealthDay

Study shows increased risk of Guillain-Barré syndrome following vaccination with recombinant zoster vaccine – “an attributable risk of 3 cases per million RZV (Shingrix) doses”.

2 Nov, 2021 | 02:45h | UTC

Risk of Guillain-Barré Syndrome Following Recombinant Zoster Vaccine in Medicare Beneficiaries – JAMA Internal Medicine (free for a limited period)

Short Review: Metronidazole-induced neurotoxicity.

2 Nov, 2021 | 02:41h | UTC

Metronidazole-induced neurotoxicity – Canadian medical Association Journal

Commentary on Twitter

The ability of metronidazole to cause neurotoxicity is not widely appreciated. Here's our quick overview led by @DanicaQuickfall, just out in @CMAJ.
https://t.co/7sggYzCzGN pic.twitter.com/miW0trFuYv

— David Juurlink (@DavidJuurlink) October 25, 2021

Short Review: Ketamine for the treatment of acute pain.

2 Nov, 2021 | 02:43h | UTC

Ketamine for the treatment of acute pain – Canadian Medical Association Journal

Commentary on Twitter

If you manage pain in hospital, low-dose ketamine should be in your toolkit. And not just in the ED.

Quick overview with @WKSilverstein & @JonZipursky in @CMAJ: https://t.co/w5h3vIMiEK pic.twitter.com/gVO7W9dcYY

— David Juurlink (@DavidJuurlink) November 1, 2021

NICE Guideline | Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome: diagnosis and management.

31 Oct, 2021 | 20:03h | UTC

Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome: diagnosis and management – National Institute for Health and Care Excellence

Commentaries:

Chronic fatigue syndrome advice scraps exercise therapy – BBC

ME exercise therapy guidance scrapped by health watchdog Nice – The Guardian

Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis.

29 Oct, 2021 | 09:49h | UTC

Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis – Intensive Care Medicine

Commentary on Twitter

Post-cardiac arrest brain injury, narrative review:
🧠pathophysiology: primary (ischemic) & secondary (reperfusion)
🧠treatment options
🧠outcomes
🧠neuroprognostication
🧠@ERC_resus @ESICM 2021 algorithm for prognostication
Open #FOAMcc #FOAMres @yourICM https://t.co/b8GRhE3MuF pic.twitter.com/q10DJVRJOp

— Intensive Care Medicine (@yourICM) October 27, 2021