RCT: Methylphenidate may improve apathy in patients with Alzheimer Disease.

Effect of Methylphenidate on Apathy in Patients With Alzheimer Disease: The ADMET 2 Randomized Clinical Trial – JAMA Neurology (free for a limited period)

Editorial: Methylphenidate for Apathy in Alzheimer Disease—Why Should We Care? (free for a limited period)

Commentary on Twitter

Small to medium effects of methylphenidate for apathy in AD. Good to see a positive symptomatic treatment trial but I wonder just how important the improvements are to patients and their families. https://t.co/nGSxlAntAd

— Robert Howard (@ProfRobHoward) September 27, 2021