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Global & Public Health (all articles)

Review: Global accessibility of therapeutics for diabetes mellitus.

13 Feb, 2022 | 21:51h | UTC

Global accessibility of therapeutics for diabetes mellitus – Nature Reviews Endocrinology (if the link is paywalled, try this one)

Related:

New WHO report maps barriers to insulin availability and suggests actions to promote universal access – “100 years after its discovery, insulin still out of reach for many living with diabetes”.

Editorial | Insulin for all: a hope yet to be realized.

One hundred years of insulin therapy.

The state of diabetes treatment coverage in 55 low-income and middle-income countries – fewer than one in ten people with diabetes in LMICs receive comprehensive care such as low-cost medicines to reduce blood sugar, blood pressure and cholesterol levels, in addition to counseling on diet, exercise and weight.

 

Babies born during pandemic’s first year score slightly lower on a developmental screening test.

11 Feb, 2022 | 08:46h | UTC

News Release: Babies born during pandemic’s first year score slightly lower on a developmental screening test – Columbia University Irving Medical Center

Original Study: Association of Birth During the COVID-19 Pandemic With Neurodevelopmental Status at 6 Months in Infants With and Without In Utero Exposure to Maternal SARS-CoV-2 Infection – JAMA Pediatrics

Editorial: Understanding the Effects of the Pandemic on Infant Development—The Preterm Problem

Commentaries:

Covid-19: Babies born during the pandemic show slight development delays – The BMJ

Pandemic birth tied to poor development – CIDRAP

 

Audio Interview: Covid-19 as an endemic disease.

11 Feb, 2022 | 08:47h | UTC

Audio Interview: Covid-19 as an Endemic Disease – New England Journal of Medicine

 

Community control strategies for scabies: A cluster randomized trial showed one dose of Ivermectin was noninferior to two doses (7 to 14 days apart) to reduce the prevalence of the disease at 12 months.

11 Feb, 2022 | 08:38h | UTC

Community control strategies for scabies: A cluster randomised noninferiority trial – PLOS Medicine

News Release: One dose of anti-parasite drug just as effective as two at reducing scabies – Murdoch Children’s Research Institute

 

M-A: The prevalence of loneliness across 113 countries.

10 Feb, 2022 | 10:08h | UTC

The prevalence of loneliness across 113 countries: systematic review and meta-analysis – The BMJ

Editorial: We need a public health approach to loneliness

News Release: Problematic levels of loneliness widespread in many countries – BMJ

 

Commentary on Twitter

https://twitter.com/robert_eres/status/1491663838013702144

 

Sweden ends COVID-19 testing as pandemic restrictions lifted – “only health care and elderly care workers and the most vulnerable will be entitled to free PCR testing if they are symptomatic, while the rest of the population will simply be asked to stay home if they show symptoms that could be COVID-19”.

10 Feb, 2022 | 10:07h | UTC

Sweden ends COVID-19 testing as pandemic restrictions lifted – Associated Press

Related:

How Denmark Decided COVID Isn’t a Critical Threat to Society – “The country became the first in the EU to lift all COVID restrictions despite leading the world in per capita infections”.

Covid: Europe set for ‘long period of tranquillity’ in pandemic, says WHO.

As Denmark scraps COVID restrictions, WHO urges caution.

Despite the ongoing spread of Omicron, some European countries have decided to lift Covid-19 restrictions.

 

A population-based study in Qatar showed previous infection provided robust protection against reinfection with the alpha, beta, and delta variants of SARS-CoV-2 (approximately 90%). However, protection against reinfection with the omicron variant was lower (around 60%).

10 Feb, 2022 | 10:04h | UTC

Protection against the Omicron Variant from Previous SARS-CoV-2 Infection – New England Journal of Medicine

 

Commentary on Twitter

 

RCT: Final analysis of efficacy and safety of single-dose J&J vaccine.

10 Feb, 2022 | 10:03h | UTC

Final Analysis of Efficacy and Safety of Single-Dose Ad26.COV2.S – New England Journal of Medicine

 

Commentary on Twitter

 

Vaccine effectiveness of heterologous CoronaVac plus Pfizer in Brazil.

10 Feb, 2022 | 10:01h | UTC

Vaccine effectiveness of heterologous CoronaVac plus BNT162b2 in Brazil – Nature Medicine

 

Commentary on Twitter

 

Systematic Review: Overuse of diagnostic testing in healthcare.

10 Feb, 2022 | 08:47h | UTC

Overuse of diagnostic testing in healthcare: a systematic review – BMJ Quality & Safety

 

WHO: Two years into COVID pandemic, most countries still face significant health service disruptions.

9 Feb, 2022 | 10:13h | UTC

Two Years into COVID Pandemic, Most Countries Still Face Significant Health Service Disruptions – Health Policy Watch

Original Report: Third round of the global pulse survey on continuity of essential health services during the COVID-19 pandemic – World Health Organization

 

Cohort Study: Physical and mental health 3 months after SARS-CoV-2 infection (long COVID) among adolescents in England.

9 Feb, 2022 | 10:12h | UTC

Physical and mental health 3 months after SARS-CoV-2 infection (long COVID) among adolescents in England (CLoCk): a national matched cohort study – The Lancet Child & Adolescent Health

See also: Long COVID symptoms in SARS-CoV-2-positive adolescents and matched controls (LongCOVIDKidsDK): a national, cross-sectional study – The Lancet Child & Adolescent Health

Editorial: Assessing the impact of the pandemic in children and adolescents: SARS-CoV-2 infection and beyond – The Lancet Child & Adolescent Health

Commentary: Long COVID and kids: more research is urgently needed – Nature

Related:

A nationwide cohort study in Denmark showed Long Covid in children is rare and mainly of short duration.

Editorial | Long covid in children and adolescents – “Risk appears low, but many questions remain”.

M-A: Persistent symptoms following SARS-CoV-2 infection among children and young people – “Higher study quality was associated with lower prevalence of all symptoms, except loss of smell and cognitive symptoms”.

Review: Long COVID symptoms in children rarely persist beyond three months.

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

 

Commentary on Twitter (thread – click for more)

 

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

9 Feb, 2022 | 10:08h | UTC

Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy: a multi-database, self-controlled case series study -medRxiv

Related:

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 

Commentary on Twitter

 

Perspective | Tracking COVID-19 infections: time for change.

9 Feb, 2022 | 10:03h | UTC

Tracking COVID-19 infections: time for change – Nature

 

Systematic Review: Video-observed therapy vs. directly observed therapy in patients with tuberculosis.

9 Feb, 2022 | 08:35h | UTC

Video-Observed Therapy Versus Directly Observed Therapy in Patients With Tuberculosis – American Journal of Preventive Medicine (link to abstract – $ for full-text)

Related: RCT: Electronic directly observed therapy is noninferior to in-person observed therapy for ensuring adherence to tuberculosis treatment.

 

Commentary on Twitter

 

ESCMID guidelines on testing for SARS-CoV-2 in asymptomatic individuals to prevent transmission in the healthcare setting.

8 Feb, 2022 | 10:18h | UTC

ESCMID guidelines on testing for SARS-CoV-2 in asymptomatic individuals to prevent transmission in the healthcare setting – Clinical Microbiology and Infection

 

Rapid control of hospital-based SARS-CoV-2 Omicron clusters through daily testing and universal use of N95 respirators.

8 Feb, 2022 | 10:09h | UTC

Rapid control of hospital-based SARS-CoV-2 Omicron clusters through daily testing and universal use of N95 respirators – Clinical Infectious Diseases

 

Opinion: Wastewater analysis can be a powerful public health tool—if it’s done sensibly.

8 Feb, 2022 | 10:08h | UTC

Opinion: Wastewater analysis can be a powerful public health tool—if it’s done sensibly – Proceedings of the National Academy of Sciences

Commentary: Wastewater monitoring for public health – University of California

Related:

CDC unveils its latest weapon in Covid-19 detection: wastewater.

CDC Report: Using Wastewater Surveillance Data to Support the COVID-19 Response — United States, 2020–2021.

Rapid, large-scale wastewater surveillance and automated reporting system enabled early detection of nearly 85% of COVID-19 cases on a University campus.

[Preprint] Wastewater genomic testing can effectively track COVID-19 variants of concern.

Human Waste Could Be The Next Big Weapon in Controlling COVID-19 – TIME

Next steps for wastewater testing to help end this pandemic — and prevent the next one – STAT

Sewage sleuths helped an Arizona town beat back Covid-19. For wastewater epidemiology, that’s just the start – STAT

The myriad ways sewage surveillance is helping fight COVID around the world – Nature

Testing sewage can give school districts, campuses and businesses a heads-up on the spread of COVID-19 – The Conversation

It’s time to begin a national wastewater testing program for Covid-19 – STAT

Coronavirus: Testing sewage an ‘easy win’ – BBC

Development of wastewater pooled surveillance of SARS-CoV-2 from congregate living settings – high sensitivity, but unable to distinguish new infectious cases from persistent convalescent shedding.

 

Fresh research says Omicron lasts much longer on surfaces than other variants – but disinfecting still works.

8 Feb, 2022 | 10:05h | UTC

Fresh research says Omicron lasts much longer on surfaces than other variants – but disinfecting still works – The Conversation

 

Sudden rise of more transmissible form of Omicron catches scientists by surprise.

8 Feb, 2022 | 10:06h | UTC

Sudden rise of more transmissible form of Omicron catches scientists by surprise – Science

Related:

Omicron’s sister variant spreads faster. So why did the one we call Omicron hit first?

[Preprint] Study suggests SARS-CoV-2 Omicron subvariants BA.2 is even more transmissible than the original variant.

BA.2 is like Omicron’s sister. Here’s what we know about it so far – The Conversation

 

Perspective | Three, four or more: what’s the magic number for booster shots?

8 Feb, 2022 | 10:03h | UTC

Three, four or more: what’s the magic number for booster shots? – Nature

 

Where did Omicron come from? Three key theories.

8 Feb, 2022 | 10:04h | UTC

Where did Omicron come from? Three key theories – Nature

 

Cluster-Randomized Trial: A multicomponent diagnostic strategy (on-site molecular testing for tuberculosis, guided restructuring of clinic workflows, and monthly feedback of quality metrics) significantly improved the rates of a confirmed diagnosis of tuberculosis within 14 days after presentation.

8 Feb, 2022 | 08:43h | UTC

Multicomponent Strategy with Decentralized Molecular Testing for Tuberculosis – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Editorial: “Excess deaths” is the best metric for tracking the pandemic.

7 Feb, 2022 | 08:54h | UTC

“Excess deaths” is the best metric for tracking the pandemic – The BMJ

Related:

The pandemic’s true death toll: millions more than official counts.

We can be confident there have been far more than 5 million global Covid deaths – “Estimating ‘excess’ fatalities, a more robust analysis method, puts the pandemic’s grim toll between 10m and 19m people”.

Global Covid-19 deaths surpass five million.

Effects of the Covid-19 pandemic on life expectancy and premature mortality in 2020 – this time series analysis showed there were more than 28 million excess years of life lost in 2020 in 31 countries.

Under-reporting of deaths limits our understanding of true burden of covid-19.

Study shows COVID-19 has caused the biggest decrease in life expectancy since World War II.

Just how do deaths due to COVID-19 stack up?

Tracking excess mortality across countries during the COVID-19 pandemic with the World Mortality Dataset.

Exploring the gap between excess mortality and COVID-19 deaths in 67 countries.

Report: Three new estimates of India’s all-cause excess mortality during the COVID-19 Pandemic – pandemic death toll estimated to be between 3.4 million and 4.9 million excess deaths.

COVID-19 has caused 6.9 million deaths globally, more than double what official reports show

 

Commentaries on Twitter

 

CDC unveils its latest weapon in Covid-19 detection: wastewater.

7 Feb, 2022 | 08:49h | UTC

CDC unveils its latest weapon in Covid-19 detection: wastewater – CNN

CDC Website: National Wastewater Surveillance System (NWSS): A new public health tool to understand COVID-19’s spread in a community – Centers for Disease Control and Prevention

Related:

CDC Report: Using Wastewater Surveillance Data to Support the COVID-19 Response — United States, 2020–2021.

Rapid, large-scale wastewater surveillance and automated reporting system enabled early detection of nearly 85% of COVID-19 cases on a University campus.

[Preprint] Wastewater genomic testing can effectively track COVID-19 variants of concern.

Human Waste Could Be The Next Big Weapon in Controlling COVID-19 – TIME

Next steps for wastewater testing to help end this pandemic — and prevent the next one – STAT

Sewage sleuths helped an Arizona town beat back Covid-19. For wastewater epidemiology, that’s just the start – STAT

The myriad ways sewage surveillance is helping fight COVID around the world – Nature

Testing sewage can give school districts, campuses and businesses a heads-up on the spread of COVID-19 – The Conversation

It’s time to begin a national wastewater testing program for Covid-19 – STAT

Coronavirus: Testing sewage an ‘easy win’ – BBC

Development of wastewater pooled surveillance of SARS-CoV-2 from congregate living settings – high sensitivity, but unable to distinguish new infectious cases from persistent convalescent shedding.

 

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