Cluster-Randomized Trial: A multicomponent diagnostic strategy (on-site molecular testing for tuberculosis, guided restructuring of clinic workflows, and monthly feedback of quality metrics) significantly improved the rates of a confirmed diagnosis of tuberculosis within 14 days after presentation.

Multicomponent Strategy with Decentralized Molecular Testing for Tuberculosis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary on Twitter

A cluster-randomized trial in 20 Ugandan health centers compared a multicomponent TB strategy with routine care. The intervention led to greater numbers of patients being tested for, receiving a diagnosis of, and being treated for confirmed TB. https://t.co/PcJDC1I0CY pic.twitter.com/AT99QVOn2S

— NEJM (@NEJM) December 28, 2021