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Critical Care

Review: How to manage a high-output stoma.

21 Mar, 2022 | 08:44h | UTC

How to manage a high-output stoma – Frontline Gastroenterology

 

Commentary on Twitter

 

Review: Challenging management dogma where evidence is non-existent, weak or outdated.

21 Mar, 2022 | 08:55h | UTC

Challenging management dogma where evidence is non-existent, weak or outdated – Intensive Care Medicine (if the link is paywalled, try this one)

 

Guideline: Management of anticoagulants and antiplatelets during acute gastrointestinal bleeding and the periendoscopic period.

18 Mar, 2022 | 09:39h | UTC

American College of Gastroenterology-Canadian Association of Gastroenterology Clinical Practice Guideline: Management of Anticoagulants and Antiplatelets During Acute Gastrointestinal Bleeding and the Periendoscopic Period – Journal of the Canadian Association of Gastroenterology

 

Commentary on Twitter

 

M-A: Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxemic respiratory failure.

18 Mar, 2022 | 09:32h | UTC

Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis – The Lancet Respiratory Medicine

Invited Commentary: The pandemic and the great awakening in the management of acute hypoxaemic respiratory failure – The Lancet Respiratory Medicine

Related:

[Preprint] RCT: In hypoxic but not critically ill patients with COVID-19, an intervention to increase prone positioning did not improve outcomes.

RCT: Awake prone positioning reduces the need for intubation in patients with COVID-19.

RCT: Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19 – no difference in intubation rates compared to standard care.

M-A: Prone positioning of nonintubated patients with Covid-19 improve oxygenation variables without any reported serious adverse events – randomized trials with patient-relevant outcomes such as the need for intubation or mortality rates are required

 

Hypertension in the hospitalized patient: an update

18 Mar, 2022 | 08:18h | UTC

Hypertension in the hospitalized patient: An update – Nefrología

 

Study shows low risk of complications after ipsilateral intravenous catheter placement in breast cancer surgery patients.

18 Mar, 2022 | 08:48h | UTC

Ipsilateral Intravenous Catheter Placement in Breast Cancer Surgery Patients – Anesthesia & Analgesia (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Cohort Study: Characteristics and outcomes of Type 2 myocardial infarction.

18 Mar, 2022 | 08:05h | UTC

Characteristics and Outcomes of Type 2 Myocardial Infarction – JAMA Cardiology (link to abstract – $ for full-text)

Commentaries:

Type 2 MI Not Uncommon in the Emergency Department – TCTMD

Type 2 Myocardial Infarction: Clinical Characteristics and Outcomes – American College of Cardiology

 

Commentary on Twitter

 

RCT: Oral contezolid vs. linezolid in adults with complicated skin and soft tissue infections.

18 Mar, 2022 | 07:54h | UTC

A Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infections – Journal of Antimicrobial Therapy (link to abstract – $ for full-text)

 

Commentary on Twitter

 

2022 ACC expert consensus decision pathway on cardiovascular sequelae of COVID-19 in adults: myocarditis and other myocardial involvement, post-acute sequelae of SARS-CoV-2 infection, and return to play.

17 Mar, 2022 | 09:26h | UTC

2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocarditis and Other Myocardial Involvement, Post-Acute Sequelae of SARS-CoV-2 Infection, and Return to Play: A Report of the American College of Cardiology Solution Set Oversight Committee – Journal of the American College of Cardiology

Commentaries:

ACC Issues Clinical Guidance on CV Consequences of COVID-19 – American College of Cardiology

ACC Releases Guidance on CV Issues With COVID-19 – TCTMD

Key Points: 2022 ACC Decision Pathway on Cardiovascular Sequelae of COVID-19

Related:

Review | Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus.

The pathogenesis and long-term consequences of Covid-19 cardiac injury: state-of-the-art review.

COVID-19 infections increase risk of heart conditions up to a year later, study finds.

 

Commentary on Twitter (thread – click for more)

 

Treatments for moderate to severe COVID-19: Cochrane evidence.

17 Mar, 2022 | 09:19h | UTC

Treatments for moderate to severe COVID-19: Cochrane evidence – Evidently Cochrane

 

Malignant Hypertension: Current perspectives and challenges.

17 Mar, 2022 | 09:03h | UTC

Malignant Hypertension: Current Perspectives and Challenges – Journal of the American Heart Association

 

Open-Label, multicenter study of Flecainide Acetate oral inhalation solution for acute conversion of recent-onset, symptomatic atrial fibrillation to sinus rhythm.

17 Mar, 2022 | 09:01h | UTC

Open-Label, Multicenter Study of Flecainide Acetate Oral Inhalation Solution for Acute Conversion of Recent-Onset, Symptomatic Atrial Fibrillation to Sinus Rhythm – Circulation: Arrythmia & Electrophysiology

 

Commentary on Twitter

 

M-A: The role of acute hypercapnia on mortality and short-term physiology in patients mechanically ventilated for ARDS.

17 Mar, 2022 | 08:31h | UTC

The role of acute hypercapnia on mortality and short-term physiology in patients mechanically ventilated for ARDS: a systematic review and meta-analysis – Intensive Care Medicine (free for a limited period)

 

Commentary on Twitter

 

Happy TRALIdays: An overview of trauma resuscitation and transfusion complications.

17 Mar, 2022 | 08:08h | UTC

Happy TRALIdays: An Overview of Trauma Resuscitation and Transfusion Complications – emDocs

 

Review: Role of imaging in rare COVID-19 vaccine multiorgan complications.

16 Mar, 2022 | 10:00h | UTC

Role of imaging in rare COVID-19 vaccine multiorgan complications – Insights into Imaging

 

Electroencephalography in delirium assessment: a scoping review.

16 Mar, 2022 | 08:31h | UTC

Electroencephalography in delirium assessment: a scoping review – BMC Neurology

 

Extracorporeal membrane oxygenation (ECMO) in COVID-19 patients: a pocket guide for radiologists.

15 Mar, 2022 | 09:51h | UTC

Extracorporeal membrane oxygenation (ECMO) in COVID-19 patients: a pocket guide for radiologists – La Radiologia Medica

 

Clinical practice guidelines for pain, agitation, delirium, immobility, and sleep disturbance in the intensive care unit.

15 Mar, 2022 | 08:45h | UTC

2021 KSCCM clinical practice guidelines for pain, agitation, delirium, immobility, and sleep disturbance in the intensive care unit – Acute and Critical Care

 

M-A: Similar outcomes with Beta-lactam monotherapy vs. combination therapy for bloodstream infections or pneumonia due to Pseudomonas aeruginosa.

15 Mar, 2022 | 08:29h | UTC

Beta-lactam monotherapy or combination therapy for bloodstream infections or pneumonia due to Pseudomonas aeruginosa: a meta-analysis – International Journal of Antimicrobial Agents (link to abstract – $ for full-text)

 

Podcast: Cardiorenal Syndrome Pearls.

15 Mar, 2022 | 08:23h | UTC

#326 NephMadness 2022: Cardiorenal Syndrome – The Curbsiders

 

Meta-analysis of randomized controlled trials comparing intraoperative red blood cell transfusion strategies.

14 Mar, 2022 | 01:47h | UTC

A Systematic Review and Meta-analysis of Randomized Controlled Trials Comparing Intraoperative Red Blood Cell Transfusion Strategies – Annals of Surgery

Related:

Systematic Review: Restrictive transfusion thresholds can safely decrease transfusions by 41% across a broad range of clinical contexts.

RCT: Among patients with acute MI and anemia, a restrictive transfusion strategy resulted in a noninferior rate of major cardiovascular events compared to a liberal transfusion strategy

Randomized trial: Liberal vs. restrictive transfusion thresholds in extremely low-birth-weight infants

Meta-Analysis: Effects of Restrictive vs. Liberal Transfusion Strategies on Longer-term Outcomes After Cardiac Surgery

Randomized Trial: In Patients Undergoing Cardiac Surgery, A Restrictive Transfusion Approach Does Not Increase the Risk of Acute Kidney Injury

Effects of restrictive red blood cell transfusion on the prognoses of adult patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials – Critical Care

Research: Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery

Transfusion Requirements After Cardiac Surgery: The TRACS Randomized Controlled Trial – JAMA

 

Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies.

14 Mar, 2022 | 01:04h | UTC

Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies – Intensive and Critical Care Nursing

 

Target temperature management following cardiac arrest: a systematic review and Bayesian meta-analysis.

14 Mar, 2022 | 01:14h | UTC

Target temperature management following cardiac arrest: a systematic review and Bayesian meta-analysis – Critical Care

Related:

ERC-ESICM guidelines on temperature control after cardiac arrest in adults.

M-A: In comatose survivors of cardiac arrest, targeted hypothermia is not associated with improved survival or better neurological outcomes vs. targeted normothermia.

RCT: In comatose survivors of out-of-hospital cardiac arrest, there was no difference in mortality and neurologic outcomes with mild (target temperature of 34 °C) vs. moderate therapeutic hypothermia (target temperature of 31 °C).

M-A: Targeted temperature management following out-of-hospital cardiac arrest – “Routine use of moderate or deep hypothermia in comatose survivors of OHCA may potentially be associated with more harm than benefit”.

RCT: In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not improve outcomes.

 

RCT: Effectiveness of Fosfomycin for treating multidrug-resistant Escherichia coli bacteremic urinary tract infections.

14 Mar, 2022 | 00:53h | UTC

Effectiveness of Fosfomycin for the Treatment of Multidrug-Resistant Escherichia coli Bacteremic Urinary Tract Infections: A Randomized Clinical Trial – JAMA Network Open

Commentaries:

The Role of Intravenous Fosfomycin: Finding Our Way Out of Dante’s Forest Dark – JAMA Network Open

Fosfomycin Not Noninferior to Comparators for Bacteremic UTI – HealthDay

‘Forgotten’ antibiotic recovered for resistant bacterial infections – University of Seville

 

Commentary on Twitter

 

Management of respiratory failure: ventilator management 101 and noninvasive ventilation.

14 Mar, 2022 | 00:45h | UTC

Management of Respiratory Failure: Ventilator Management 101 and Noninvasive Ventilation – Clinical Journal of the American Society of Nephrology

 

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