Critical Care
Review: Drug-induced acute kidney injury.
14 Mar, 2022 | 00:48h | UTCDrug-Induced Acute Kidney Injury – Clinical Journal of the American Society of Nephrology
RCT: Safety and efficacy of three enteral feeding strategies in patients with severe stroke.
11 Mar, 2022 | 09:51h | UTCSafety and efficacy of three enteral feeding strategies in patients with severe stroke in China (OPENS): a multicentre, prospective, randomised, open-label, blinded-endpoint trial – The Lancet Neurology (link to abstract – $ for full-text)
Association between statin use and daptomycin-related musculoskeletal adverse events: A mixed approach combining a meta-analysis and a disproportionality analysis.
11 Mar, 2022 | 09:39h | UTC
RCT: In patients with refractory out-of-hospital cardiac arrest, a strategy of intra-arrest transport, extracorporeal cardiopulmonary resuscitation, and immediate invasive assessment did not significantly improve survival with a favorable neurological outcome (OR 1.63; 95% CI 0.93 to 2.85; P = .09).
10 Mar, 2022 | 10:57h | UTCEffect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Early Invasive Therapy for Out-of-Hospital Cardiac Arrest – American College of Cardiology
Commentary on Twitter
https://twitter.com/JAMA_current/status/1496183512025677829
Meta-analysis of randomized trials: benefits and harms of direct oral anticoagulation and low molecular weight heparin for thromboprophylaxis in patients undergoing non-cardiac surgery.
10 Mar, 2022 | 10:48h | UTC
Commentary on Twitter
https://twitter.com/KariTikkinen/status/1501532156786577415
Perspective: Once viewed as a promising COVID-19 treatment, convalescent plasma falls out of favor.
10 Mar, 2022 | 10:47h | UTCOnce Viewed as a Promising COVID-19 Treatment, Convalescent Plasma Falls Out of Favor – JAMA
Guideline: Implementing advance care plans in the peri-operative period, including plans for cardiopulmonary resuscitation.
10 Mar, 2022 | 10:40h | UTC
RCT: The SGLT2 inhibitor empagliflozin in patients hospitalized for acute heart failure.
9 Mar, 2022 | 10:04h | UTC
ACS Best Practice Guidelines: Spine injury.
9 Mar, 2022 | 10:00h | UTCSpine Injury – American College of Surgeons
News Release: New guidelines will help trauma centers treat spinal injury patients
RCT: In patients with trauma-related hemorrhagic shock receiving prehospital care, there was no benefit from resuscitation with blood products compared to 0.9% sodium chloride.
9 Mar, 2022 | 09:55h | UTCInvited commentary: Prehospital blood transfusion: who benefits? – The Lancet Haematology
Commentary on Twitter
NEW research—resuscitation with blood products in patients with trauma-related haemorrhagic shock receiving prehospital care: results of #RePHILL, a randomised, controlled, phase 3 trial #openaccess #EmergencyMedicine 🚑🩸https://t.co/Ci0lMMCryX pic.twitter.com/iWEtV12N1r
— The Lancet Haematology (@TheLancetHaem) March 8, 2022
IDSA Guidance on the treatment of antimicrobial-resistant Gram-Negative infections – A focus on extended-spectrum β-lactamase producing Enterobacterales, Carbapenem-resistant Enterobacterales, and Pseudomonas aeruginosa with difficult-to-treat resistance.
9 Mar, 2022 | 08:51h | UTCRelated:
IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.
Doing more can be worse: ten common errors in the ICU.
8 Mar, 2022 | 08:51h | UTCDoing More Can Be Worse: Ten Common Errors in the ICU – ICU Management & Practice
Fighting against sudden cardiac death: need for a paradigm shift—Adding near-term prevention and pre-emptive action to long-term prevention.
8 Mar, 2022 | 08:39h | UTC
Commentary on Twitter
Fighting against #SuddenCardiacDeath: need for a paradigm shift—Adding near-term prevention and pre-emptive action to long-term prevention https://t.co/5xLeUAB9QD @escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/IGzZ8dmLd6
— European Society of Cardiology Journals (@ESC_Journals) March 7, 2022
Case report: Nonthrombotic pulmonary embolism secondary to cyanoacrylate embolization of gastric varices.
8 Mar, 2022 | 08:35h | UTC
RCT: In patients with stable chest pain with intermediate pretest probability of obstructive coronary artery disease, an initial diagnostic imaging strategy based on CT angiography resulted in similar risks of major adverse cardiovascular events compared to invasive coronary angiography.
7 Mar, 2022 | 00:55h | UTCCT or Invasive Coronary Angiography in Stable Chest Pain – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: DISCHARGE Hailed as a Big Step Forward for CTA in Stable Chest Pain – TCTMD
Commentary on Twitter
Among patients referred for invasive coronary angiography because of stable chest pain and intermediate pretest probability of CAD, the risk of major adverse CV events was similar in the CT group and the ICA group. #ECR22 https://t.co/KnuQo0juxE pic.twitter.com/Sf70dqfgKP
— NEJM (@NEJM) March 4, 2022
RCT: Anterior–lateral electrode position is more effective compared to anterior–posterior electrode position for cardioverting atrial fibrillation.
7 Mar, 2022 | 00:45h | UTCCommentary: Anterior-Lateral or Anterior-Posterior Pads for A-fib Cardioversion? – JournalFeed
Commentary on Twitter
#OriginalResearch In this multicenter RCT of 468 patients, anterior-lateral electrode position was more effective than anterior-posterior electrode position for ⚡cardioversion of #Afib #AHAJournalshttps://t.co/XJlxe7e7Ed pic.twitter.com/hA4wGb6Pak
— Circulation (@CircAHA) November 24, 2021
Systematic Review: Anticoagulants for people hospitalized with COVID‐19.
7 Mar, 2022 | 00:48h | UTCAnticoagulants for people hospitalised with COVID‐19 – Cochrane Library
Related: Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week.
Systematic Review: Prediction of good neurological outcome in comatose survivors of cardiac arrest.
7 Mar, 2022 | 00:40h | UTC
Commentary on Twitter
Predicting good neuro outcome in comatose cardiac arrest survivors? Look at
🧠 GCS motor 4/5
🧠 normal NSE
🧠 SSEP N20 wave amplitude > 4 μV or continuous EEG background without discharges
🧠 no diffusion restriction in cortex or deep grey matter on MRI
SR https://t.co/ixkMvErdux pic.twitter.com/GjeuTLgDlb— Intensive Care Medicine (@yourICM) March 4, 2022
Ten myths about albumin.
7 Mar, 2022 | 00:44h | UTCTen myths about albumin – Intensive Care Medicine (free for a limited period)
Commentary on Twitter
Albumin, 10 myths
1️⃣leaks into interstitium
2️⃣ ⬇️volume expansion vs artificial colloids
3️⃣ ⬇️AKI
4️⃣ sepsis: ⬆️survival
5️⃣ ⬆️diuretics effects
6️⃣RRT: ⬆️ fluid removal
7️⃣cirrhosis: ⬇️mortality
8️⃣TBI: ⬆️mortality
9️⃣correcting hypoalb ⬇️mortality
🔟 ⬆️NaCl
📎 https://t.co/nGOHOLYRqY pic.twitter.com/YroygQNNUk— Intensive Care Medicine (@yourICM) March 5, 2022
WSES/GAIS/WSIS/SIS-E/AAST global clinical pathways for patients with skin and soft tissue infections.
7 Mar, 2022 | 00:09h | UTC
WSES guidelines on blunt and penetrating bowel injury: diagnosis, investigations, and treatment.
7 Mar, 2022 | 00:11h | UTC
Arterial blood gas analysis: as safe as we think? A multicentre historical cohort study.
7 Mar, 2022 | 00:00h | UTCArterial blood gas analysis: as safe as we think? A multicentre historical cohort study – ERJ Open
Hepatorenal Syndrome Type 1: From diagnosis ascertainment to goal-oriented pharmacologic therapy.
6 Mar, 2022 | 23:47h | UTC
Distribution of delirium motor subtypes in the intensive care unit: a systematic scoping review.
6 Mar, 2022 | 23:38h | UTC
RCT: Preliminary trial suggests neostigmine may improve intra-abdominal hypertension and increase defecation in patients with acute pancreatitis.
6 Mar, 2022 | 23:39h | UTC