M-A: Targeted temperature management following out-of-hospital cardiac arrest – “Routine use of moderate or deep hypothermia in comatose survivors of OHCA may potentially be associated with more harm than benefit”.

Targeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets – Intensive Care Medicine (free for a limited period)

Related: RCT: In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not improve outcomes.

Commentary on Twitter

#TTM post #OHCA, SR/NMA:
❄️deep, moderate & mild hypothermia not improve survival/functional outcome vs normothermia
❄️deep vs moderate hypothermia may not improve survival with good outcome
❄️higher incidence of arrhythmia with moderate & deep hypothermiahttps://t.co/Z18v5HSXyr pic.twitter.com/6TQf8QPKiA

— Intens Care Med (@yourICM) August 14, 2021