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Cardiology (all articles)

Cluster RCT: A household salt substitution intervention is a cost-effective intervention for preventing stroke and improving quality of life.

29 Mar, 2022 | 10:16h | UTC

Cost-effectiveness of a Household Salt Substitution Intervention: Findings From 20,995 Participants of the Salt Substitute and Stroke Study (SSaSS) – Circulation

Commentary: ACC: Use of Salt Substitute to Prevent Stroke Is Cost-Saving – HealthDay

Original Study: #ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

Related:

Former CDC director: Low sodium salt could save millions of lives – CNN

Is salt good for you after all? The evidence says no.

Systematic Review: Altered dietary salt intake for people with chronic kidney disease.

New WHO benchmarks help countries reduce salt intake and save lives.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Meta-Analysis: Effect of Reduction in Dietary Sodium on Blood Pressure Levels

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

 


Cohort Study: Coronary artery and cardiac disease are common in patients with type 2 myocardial infarction.

29 Mar, 2022 | 10:14h | UTC

Coronary Artery and Cardiac Disease in Patients With Type 2 Myocardial Infarction: A Prospective Cohort Study – Circulation

Commentary: AHA News: Undiagnosed Heart Disease May Be Common in People With Heart Attacks Not Caused by Clots – HealthDay

 

Commentary on Twitter

 


Myocarditis and pericarditis after COVID-19 vaccination: clinical management guidance for healthcare professionals.

29 Mar, 2022 | 10:09h | UTC

Myocarditis and pericarditis after COVID-19 vaccination: clinical management guidance for healthcare professionals – UK Health Security Agency

Related:

Myocarditis following a third Pfizer vaccination dose in military recruits in Israel.

Myocarditis following COVID-19 BNT162b2 vaccination among adolescents in Hong Kong.

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 


Meta-analysis of randomized trials: GLP1 receptor agonists increase the risk of gallbladder and biliary diseases (RR, 1.37; 95% CI, 1.23-1.52).

29 Mar, 2022 | 10:02h | UTC

Association of Glucagon-Like Peptide-1 Receptor Agonist Use With Risk of Gallbladder and Biliary Diseases: A Systematic Review and Meta-analysis of Randomized Clinical Trials – JAMA Internal Medicine (free for a limited period)

Commentary: GLP-1 Receptor Agonists: How Safe Are They for the Gallbladder?— Link with gallbladder, biliary diseases could be due to weight loss associated with class of drug – MedPage Today (free registration required)

 


Crossover RCT: Effects of experimental sleep restriction on energy intake, energy expenditure, and visceral obesity.

29 Mar, 2022 | 08:31h | UTC

Effects of Experimental Sleep Restriction on Energy Intake, Energy Expenditure, and Visceral Obesity – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentary: Lack of sleep increases unhealthy abdominal fat, study finds – Mayo Clinic

Related: RCT: Advising overweight patients to increase sleep duration may reduce caloric intake.

 


M-A: Comparative effectiveness of statins on non-HDL cholesterol in people with diabetes and at risk of cardiovascular disease.

25 Mar, 2022 | 10:01h | UTC

Comparative effectiveness of statins on non-high density lipoprotein cholesterol in people with diabetes and at risk of cardiovascular disease: systematic review and network meta-analysis – The BMJ

News Release: Best statins for reducing cardiovascular risk in people with diabetes found – University of Manchester

 

Commentary on Twitter

 


Review: How to improve compliance to hypertension treatment.

28 Mar, 2022 | 08:31h | UTC

How to improve compliance to hypertension treatment – European Society of Cardiology

 

Commentary on Twitter

 


RCT: Nitroglycerin does not prevent radial occlusion after transradial access in the cath lab.

28 Mar, 2022 | 08:26h | UTC

Randomized Clinical Trial on Prevention of Radial Occlusion After Transradial Access Using Nitroglycerin: PATENS Trial – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)

Commentary: Nitroglycerin Given Early or Late Fails to Prevent Radial Artery Occlusion: PATENS – TCTMD

 


Studies show same-day discharge post–transcatheter aortic valve replacement is feasible.

25 Mar, 2022 | 09:58h | UTC

Study 1: Same-Day Discharge Post–Transcatheter Aortic Valve Replacement During the COVID-19 Pandemic: The Multicenter PROTECT TAVR Study – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)

Study 2: Feasibility and Safety of Same-Day Discharge Following Transfemoral Transcatheter Aortic Valve Replacement – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)

Editorial: Did the COVID-19 Pandemic Just Turn TAVR Into an Outpatient Procedure?

Commentary: ‘Right Time, Right Moment’: Same-Day Discharge After TAVI Safe, Feasible – TCTMD

 


RCT: Among patients with heart failure and atrial fibrillation, an ablation-based rhythm-control strategy was not significantly better than a rate-control strategy for improving all-cause mortality and heart failure events (hazard ratio 0.71; 95% CI 0.49-1.03; p=0.066).

25 Mar, 2022 | 09:59h | UTC

Randomized Ablation-Based Rhythm-Control Versus Rate-Control Trial in Patients with Heart Failure and Atrial Fibrillation: Results from the RAFT-AF trial – Circulation

Related:

Update on management of atrial fibrillation in heart failure: a focus on ablation.

Review: Cryoballoon ablation as initial treatment for atrial fibrillation.

Subgroup analysis of RCT suggests early rhythm control therapy is beneficial for patients with atrial fibrillation and heart failure.

Meta-Analysis: Catheter Ablation Improves Outcomes in Patients with Atrial Fibrillation Complicated with Heart Failure

Catheter Ablation for Atrial Fibrillation Improves Outcomes in Heart Failure with Reduced Ejection Fraction

M-A: In patients with atrial fibrillation, catheter ablation was associated with a 38% reduction in recurrence and a 68% reduction in hospitalizations. The rate of serious complications was 4.2% with ablation vs. 2.8% in the antiarrhythmic group, a difference that was not statistically significant.

CABANATrial: Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation

 


The Role of Cardioprotection in Cancer Therapy Cardiotoxicity: JACC: CardioOncology State-of-the-Art Review.

25 Mar, 2022 | 08:51h | UTC

The Role of Cardioprotection in Cancer Therapy Cardiotoxicity: JACC: CardioOncology State-of-the-Art Review – JACC: CardioOncology

 


Review | Psychological stress and heart disease: fact or folklore?

23 Mar, 2022 | 10:30h | UTC

Psychological Stress and Heart Disease: Fact or Folklore? – The American Journal of Medicine

 


Consensus Statement: Appropriateness criteria for evaluation and prevention of renal damage in the patient undergoing contrast medium examinations.

23 Mar, 2022 | 10:11h | UTC

SIRM-SIN-AIOM: appropriateness criteria for evaluation and prevention of renal damage in the patient undergoing contrast medium examinations—consensus statements from Italian College of Radiology (SIRM), Italian College of Nephrology (SIN) and Italian Association of Medical Oncology (AIOM) – La radiologia medica

Related:

Another study shows intravenous radiocontrast use is not associated with reduced kidney function

ACR/NKF Consensus Statement: “The Risk of Acute Kidney Injury Developing in Patients with Reduced Kidney Function Following Exposure to Intravenous Iodinated Contrast Media has Been Overstated”

 


ANN Guideline: Stroke prevention in symptomatic large artery intracranial atherosclerosis practice advisory.

22 Mar, 2022 | 09:51h | UTC

Stroke Prevention in Symptomatic Large Artery Intracranial Atherosclerosis Practice Advisory: Report of the AAN Guideline Subcommittee – Neurology

News Release: AAN issues guidance on preventing second stroke in those with plaque in brain arteries – American Academy of Neurology

 


Review: Diagnosis and management of cirrhotic cardiomyopathy.

23 Mar, 2022 | 09:41h | UTC

Diagnosis and Management of Cirrhotic Cardiomyopathy – Journal of Clinical and Experimental Hepatology

 


AHA Scientific Statement: Understanding the importance of the lay responder experience in out-of-hospital cardiac arrest.

22 Mar, 2022 | 09:49h | UTC

Understanding the Importance of the Lay Responder Experience in Out-of-Hospital Cardiac Arrest: A Scientific Statement From the American Heart Association – Circulation

News Release: Lay rescuers who do CPR are heroes and survivors, new statement addresses their perspective – American Heart Association

Commentary: AHA News: CPR ‘Heroes’ Need More Support, Report Says – HealthDay

Related study: Pre-post study: The introduction of a text-message alert system to alert volunteers close to a cardiac arrest patient at home was associated with increased survival to hospital discharge.

 


Review: When to operate after SARS-CoV-2 infection?

22 Mar, 2022 | 09:44h | UTC

When to operate after SARS-CoV-2 infection? A review on the recent consensus recommendation of the DGC/BDC and the DGAI/BDA – Langenbeck’s Archives of Surgery

Related:

Guideline Update: Timing of elective surgery and risk assessment after SARS-CoV-2 infection – “The guidance remains that patients should avoid elective surgery within 7 weeks of infection, unless the benefits of doing so exceed the risk of waiting”.

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

 


Study shows low risk of acute myocardial infarction after ophthalmologic procedures, confirming previous knowledge that preoperative evaluation may be unnecessary for most patients.

22 Mar, 2022 | 08:47h | UTC

Risk for Acute Myocardial Infarction After Ophthalmologic Procedures – Annals of Internal Medicine (link to abstract – $ for full-text)

Summary for patients: Summary for Patients: Risk for Heart Attack After Eye Procedures

Editorial: Preoperative Evaluation Can Delay Ophthalmologic Surgery Without Improving Outcomes ($)

Commentary: Ophthalmologic Procedures Not Tied to Increased AMI Risk – HealthDay

Related:

Position Statement: Preoperative Care for Cataract Surgery – “In spite of evidence debunking the utility of testing before cataract surgery, studies suggest that medical testing and the use of medical consultations before cataract surgery continue to increase”.

Study: Prevalence and Cost of Care Cascades After Low-Value Preoperative Electrocardiogram for Cataract Surgery

Evaluation of an Intervention to Reduce Low-Value Preoperative Care for Patients Undergoing Cataract Surgery

Systematic Review: Routine Preoperative Medical Testing for Cataract Surgery

Preoperative Medical Testing in Medicare Patients Undergoing Cataract Surgery – New England Journal of Medicine

 

Commentary on Twitter

 


Myocarditis following a third Pfizer vaccination dose in military recruits in Israel.

21 Mar, 2022 | 09:37h | UTC

Myocarditis Following a Third BNT162b2 Vaccination Dose in Military Recruits in Israel – JAMA

Related:

Myocarditis following COVID-19 BNT162b2 vaccination among adolescents in Hong Kong.

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 


M-A: Prevalence of coronary microvascular disease and coronary vasospasm in patients with nonobstructive coronary artery disease.

21 Mar, 2022 | 08:47h | UTC

Prevalence of Coronary Microvascular Disease and Coronary Vasospasm in Patients With Nonobstructive Coronary Artery Disease: Systematic Review and Meta‐Analysis – Journal of the American Heart Association

 


Editorial | BNP: Biomarker Not Perfect in heart failure with preserved ejection fraction.

21 Mar, 2022 | 08:31h | UTC

Editorial: BNP: Biomarker Not Perfect in heart failure with preserved ejection fraction – European Heart Journal

Original Study: Heart failure with preserved ejection fraction in patients with normal natriuretic peptide levels is associated with increased morbidity and mortality – European Heart Journal (link to abstract – $ for full-text)

 


Blood pressure hyperreactivity to standing: a predictor of adverse outcome in young hypertensive patients.

21 Mar, 2022 | 08:30h | UTC

Blood Pressure Hyperreactivity to Standing: a Predictor of Adverse Outcome in Young Hypertensive Patients – Hypertension (link to abstract – $ for full-text)

News Release: If blood pressure rises upon standing, so may risk for heart attack – American Heart Association

Commentaries:

BP Hyperreactivity to Standing Tied to CV, Renal Events – HealthDay

Young hypertensives: increase in blood pressure on standing linked to increase in adverse events – MedicalResearch

 


RCT: Cocoa flavanol supplementation shows promise for the prevention of cardiovascular disease events.

18 Mar, 2022 | 08:54h | UTC

Effect of cocoa flavanol supplementation for prevention of cardiovascular disease events: The COSMOS randomized clinical trial – American Journal of Clinical Nutrition

Commentary: New trial finds signs of preventive cardiovascular effects for cocoa flavanols – Brigham and Women’s Hospital

 

Commentary on Twitter (thread – click for more)

 


Hypertension in the hospitalized patient: an update

18 Mar, 2022 | 08:18h | UTC

Hypertension in the hospitalized patient: An update – Nefrología

 


AHA Scientific Statement: Advances in managing transition to adulthood for adolescents with congenital heart disease.

18 Mar, 2022 | 08:19h | UTC

Advances in Managing Transition to Adulthood for Adolescents With Congenital Heart Disease: A Practical Approach to Transition Program Design: A Scientific Statement From the American Heart Association – Journal of the American Heart Association

News Release: For youth with a heart defect, shift to adult-focused care is key to health, quality of life – American Heart Association

 


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