Daily Archives: March 3, 2022
WHO: COVID-19 pandemic triggers a 25% increase in the prevalence of anxiety and depression worldwide.
3 Mar, 2022 | 09:44h | UTCNews Release: COVID-19 pandemic triggers 25% increase in prevalence of anxiety and depression worldwide – World Health Organization
Scientific Brief: Mental health and COVID-19: Early evidence of the pandemic’s impact – World Health Organization
Commentary on Twitter (thread – click for more)
? #COVID19 pandemic triggers 25% increase in prevalence of anxiety & depression worldwide: New WHO publication
More: https://t.co/QFiH7j312f#MentalHealth?: Getty Images/J. Paget pic.twitter.com/iX15sbHXcW
— World Health Organization (WHO) (@WHO) March 2, 2022
RCT: Aspirin and unfractionated heparin increase the risk of symptomatic intracranial hemorrhage in patients undergoing endovascular treatment for ischemic stroke.
3 Mar, 2022 | 08:53h | UTCSafety and efficacy of aspirin, unfractionated heparin, both, or neither during endovascular stroke treatment (MR CLEAN-MED): an open-label, multicentre, randomised controlled trial – The Lancet (link to abstract – $ for full-text)
RCT: Nirsevimab for prevention of RSV in healthy late-preterm and term infants.
3 Mar, 2022 | 09:42h | UTCCommentaries:
Nirsevimab Protects Late-Preterm, Term Infants from RSV-Related Lower RTI, Study Finds – AJMC
Nirsevimab Prophylaxis Wards Off RSV Infections in Healthy Infants— Monoclonal antibody showed 74.5% efficacy against RSV infections requiring medical care – MedPage Today (free registration required)
Related: Randomized trial: Single-dose nirsevimab for prevention of RSV in preterm infants
National, regional, and global causes of mortality in 5–19-year-olds from 2000 to 2019: a systematic analysis.
3 Mar, 2022 | 08:51h | UTCInvited commentary: Child and adolescent deaths: a call for strengthening mortality surveillance systems – The Lancet Global Health
Cohort Study: High-sensitivity Troponin I after cardiac surgery and 30-day mortality.
3 Mar, 2022 | 08:54h | UTCHigh-Sensitivity Troponin I after Cardiac Surgery and 30-Day Mortality – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
NEJM study evaluates levels of HS Troponin after cardiac surgery and risk of death – MedicalResearch
Commentary on Twitter
The levels of high-sensitivity troponin I associated with an increased risk of death within 30 days after cardiac surgery are higher than levels currently used to define clinically important periprocedural myocardial injury. https://t.co/bnwPzQmh1h pic.twitter.com/pdmx23jPdz
— NEJM (@NEJM) March 2, 2022
[News release – not published yet] Study finds blood pressure cuff size matters, affects blood pressure readings.
3 Mar, 2022 | 08:47h | UTCStudy finds blood pressure cuff size matters, affects blood pressure readings – AHA Newsroom
M-A: Use of tocilizumab and sarilumab alone or in combination with corticosteroids for covid-19.
3 Mar, 2022 | 08:49h | UTCEditorial: Treatment of severe covid-19 with interleukin 6 receptor inhibition – BMJ Medicine
Related study (just published): Mortality Rates Among Hospitalized Patients With COVID-19 Infection Treated With Tocilizumab and Corticosteroids: A Bayesian Reanalysis of a Previous Meta-analysis – JAMA Network Open
Myocarditis following COVID-19 BNT162b2 vaccination among adolescents in Hong Kong.
3 Mar, 2022 | 08:43h | UTCMyocarditis Following COVID-19 BNT162b2 Vaccination Among Adolescents in Hong Kong – JAMA Pediatrics
Commentary: Study: Dosing change could reduce COVID-19 vaccine heart side effect in teens – UPI
Related:
Myocarditis after BNT162b2 vaccination in Israeli adolescents.
[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.
Heart-inflammation risk from Pfizer COVID vaccine is very low.
COVID-19 in people with rheumatic diseases: risks, outcomes, treatment considerations.
3 Mar, 2022 | 08:46h | UTC
Commentary on Twitter
Our latest #Review is online now. #COVID-19 risks, outcomes and treatment considerations in #rheumatic disease.
Read it for #free here: https://t.co/WsmuyoFNGT@philipcrobinson pic.twitter.com/I4RWh0Gftr
— NatRevRheumatol (@NatRevRheumatol) February 28, 2022
RCT: Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis.
3 Mar, 2022 | 08:40h | UTC
Commentary on Twitter
Therapeutic drug monitoring‑guided pip/tazo infusion vs fixed dose in #sepsis, TARGET RCT:
?no significant difference in mean SOFA
⬇️28-day mortality + ⬆️ clinical/microbiological cure if TDM (no statistical significance)
Results https://t.co/cLS1OQ173I
⬇️Below visual abstract pic.twitter.com/jRjzfNLj1T— Intensive Care Medicine (@yourICM) March 1, 2022
RCT: In patients with early-stage lung cancer, video-assisted thoracoscopic lobectomy is associated with better recovery of physical function at 5 weeks.
3 Mar, 2022 | 08:42h | UTCVideo-Assisted Thoracoscopic or Open Lobectomy in Early-Stage Lung Cancer – NEJM Evidence
Commentary on Twitter
For patients with early-stage #LungCancer, resection by video-assisted thoracoscopic surgery was superior to open resection with respect to postoperative recovery of physical function as shown in a randomized trial. @ekslim @RBandH #VATS #OncoAlert https://t.co/j23CgZp5U5 pic.twitter.com/UsIx3D8Zem
— NEJM Evidence (@NEJMEvidence) January 19, 2022
Prevalence trends of site-specific osteoarthritis from 1990 to 2019: findings from the Global Burden of Disease Study 2019.
3 Mar, 2022 | 08:27h | UTCNews Release: Study reveals a persistently high burden of osteoarthritis across the globe – Wiley
RCT: In patients with acute coronary syndrome, clopidogrel monotherapy after 1 to 2 months of dual antiplatelet therapy was NOT noninferior to 12 months of dual antiplatelet therapy.
3 Mar, 2022 | 08:32h | UTCComparison of Clopidogrel Monotherapy After 1 to 2 Months of Dual Antiplatelet Therapy With 12 Months of Dual Antiplatelet Therapy in Patients With Acute Coronary Syndrome: The STOPDAPT-2 ACS Randomized Clinical Trial – JAMA Cardiology (free for a limited period)
Commentary on Twitter
Study found the effectiveness of clopidogrel monotherapy after 1 to 2 months of dual antiplatelet therapy is inconclusive, and further investigation is needed to define the optimal therapy for patients with acute coronary syndromes. https://t.co/aqxk39TjY3
— JAMA Cardiology (@JAMACardio) March 2, 2022
Observational study suggests norepinephrine is a better choice than epinephrine in cardiac arrest patients with post-resuscitation shock.
3 Mar, 2022 | 08:38h | UTCEpinephrine versus norepinephrine in cardiac arrest patients with post-resuscitation shock – Intensive Care Medicine (link to abstract – $ for full-text)
Noradrenaline better vs adrenaline in cardiac arrest pts with post #resus shock?
?766 pts, 5 ?
? noradrenaline better survival/neuro-outcome: all-cause & cardiovascular mortality significantly ⬆️ with epinephrine
?️ Results #FOAMcc https://t.co/ihuEPg8sGq
⬇️ Visual Abstract pic.twitter.com/aakmkpPxXf— Intensive Care Medicine (@yourICM) February 24, 2022
A low-energy diet shows promise for reducing the symptoms of fibromyalgia.
3 Mar, 2022 | 08:23h | UTCEarly Relationships of a Low-Energy Diet With Symptoms of Fibromyalgia ACR Open Rheumatology
Commentary: Fibromyalgia Patients See Rapid Benefit From Low-Cal Diet — With marked symptom reduction in just 3 weeks, weight loss not a factor – MedPage Today (free registration required)
Guideline: Management of Clostridioides difficile infection in hematopoietic cell transplant recipients.
3 Mar, 2022 | 08:17h | UTCSee other articles in the series:
The effects of foods on LDL cholesterol levels: A systematic review of the accumulated evidence from systematic reviews and meta-analyses of randomized controlled trials.
3 Mar, 2022 | 08:22h | UTC
Cancer risks other than female breast and ovarian cancers associated with BRCA1 and BRCA2 pathogenic variants.
3 Mar, 2022 | 08:14h | UTCCancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants – Journal of Clinical Oncology
Commentary: Faulty BRCA genes linked to prostate and pancreatic cancers – University of Cambridge
RCT: In operated patients with head and neck cancer, chemoradiotherapy with weekly cisplatin is noninferior to 3-weekly cisplatin and is associated with reduced toxicity.
3 Mar, 2022 | 08:11h | UTC
Commentary from the author on Twitter
Dear friends,
Finally, the results of JCOG1008, post operative CRT (weekly CDDP vs. 3-weekly CDDP) has published on Journal of Oncology.
Weekly CDDP+RT is a new treatment option with equal efficacy and better safety profile.
Please check the manuscript!!https://t.co/XG6mkGeo4Y— Naomi Kiyota (@kiyota_naomi) March 1, 2022
Coccidioidomycosis: A Contemporary review.
3 Mar, 2022 | 08:20h | UTCCoccidioidomycosis: A Contemporary Review – Infectious Diseases and Therapy
(Epi)genetic predisposing factors found in one-third of children diagnosed with Wilms tumor.
3 Mar, 2022 | 08:10h | UTC
SEOM-GECP-GETTHI Clinical Guidelines for the treatment of patients with thymic epithelial tumors.
3 Mar, 2022 | 08:08h | UTC
Meta-analysis showed a 2.4-fold increased risk of cancer in patients with pediatric-onset inflammatory bowel disease.
3 Mar, 2022 | 08:06h | UTCCommentary: Kids With IBD Need Close Monitoring as They Grow Up — Meta-analysis confirms: substantially increased cancer risk in adulthood – MedPage Today (free registration required)
Concise Review: A Practical 5-step approach to nausea and vomiting.
3 Mar, 2022 | 08:04h | UTCA Practical 5-Step Approach to Nausea and Vomiting – Mayo Clinic Proceedings
Association of Mesh and fixation options with reoperation risk after laparoscopic groin hernia surgery: A Swedish hernia registry study of 25,190 totally extraperitoneal and transabdominal preperitoneal repairs.
3 Mar, 2022 | 08:07h | UTC