TOP 10 Medical News Stories

Related Cochrane Review: Kangaroo mother care to reduce morbidity and mortality in low birthweight infants (free) AND Summary: Kangaroo mother care to reduce morbidity and mortality in low birthweight infants (free)

6 – Primary Prevention of Cardiovascular Disease – JAMA (free for a limited period)

Original Guideline: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease (free guideline and resources)

7 – Vaping Illness Update: FDA Warns Public to Stop Using Tetrahydrocannabinol (THC)-Containing Vaping Products and Any Vaping Products Obtained Off the Street – U.S. Food & Drug Administration (free)

8 – Advice to Young Psychiatrists From a Very Old One – Psychiatric Times (free)

9 – Highlight negative results to improve science – Nature (free)

10 – Predictors of gastrointestinal bleeding in adult ICU patients: a systematic review and meta-analysis – Intensive Care Medicine (free)

Source: Grupo UTIclínica – HCFMUSP

Fri October 4 – 10 Stories of The Day!

4 Oct, 2019 | 08:34h | UTC

1 – 2019 EACTS/EACTA/EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery – Interactive CardioVascular and Thoracic Surgery (free)

2 – Management of Severe Asthma: a European Respiratory Society/American Thoracic Society Guideline – European Respiratory Journal (free PDF)

3 – Blame rising cancer overdiagnosis on ‘irrational exuberance’ for early detection – STAT (free)

4 – A Comprehensive Algorithm for Management of Neuropathic Pain – Pain Medicine (free)

5 – Medical treatment of primary aldosteronism – European Journal of Endocrinology (free)

6 – Enhanced Recovery After Cardiac Surgery (ERAS Cardiac) Recommendations: An Important First Step—But There Is Much Work to Be Done – Cardiothoracic and Vascular Anesthesia (free)

Original Article: Enhanced Recovery After Surgery (ERAS) Guidelines for Perioperative Care in Cardiac Surgery (free guideline and commentary)

7 – Supplement: Obstructive Sleep Apnea – Cleveland Clinic Journal of Medicine (free articles)

– Introduction—Obstructive sleep apnea: A wake-up call for better outcomes

– Obstructive sleep apnea basics

– Sleep apnea and the heart

– Beyond heart health: Consequences of obstructive sleep apnea

– Positive airway pressure: Making an impact on sleep apnea

– Alternative interventions for obstructive sleep apnea

8 – 2019 Update in perioperative cardiovascular medicine – Cleveland Clinic Journal of Medicine (free)

9 – Parental alcohol consumption and the risk of congenital heart diseases in offspring: An updated systematic review and meta-analysis – European Journal of Preventive Cardiology (free)

Commentaries: Fathers-to-be should avoid alcohol six months before conception – European Society of Cardiology (free) AND Dads-to-be should stop drinking 6 months before conception for baby’s heart health, study says – CNN (free)

10 – Association of Use of Oral Contraceptives With Depressive Symptoms Among Adolescents and Young Women – JAMA Psychiatry (link to abstract – $ for full-text)

Commentaries: Teens taking oral contraceptives may be at increased risk for depressive symptoms – Brigham and Women’s Hospital (free) AND Teen OC Users More Likely to Report Depressive Symptoms – NEJM (free)

Thu October 3 – 10 Stories of The Day!

3 Oct, 2019 | 10:24h | UTC

1 – Community-wide Screening for Tuberculosis in a High-Prevalence Setting – New England Journal of Medicine (free)

2 – Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Cooling cardiac arrest patients may protect brain function – UPI (free) AND Hypothermia Helps After Cardiac Arrest With Nonshockable Rhythm – MedPage Today (free registration required)

3 – Effect of Postextubation High-Flow Nasal Oxygen With Noninvasive Ventilation vs High-Flow Nasal Oxygen Alone on Reintubation Among Patients at High Risk of Extubation Failure: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Added Benefit of Noninvasive Ventilation to High-Flow Nasal Oxygen to Prevent Reintubation in Higher-Risk Patients (free for a limited period)

4 – Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a clinical practice guideline – The BMJ (free)

Editorial: Personalised and risk based cancer screening (free)

Commentaries: Guideline Moves Away from Colorectal Cancer Screening for Some – NEJM Journal Watch (free) AND First Guideline to Say Colon Cancer Screening Is Not for All – Medscape (free registration required)

Related Guidelines: Colorectal Cancer Screening for Average‐risk Adults (guidelines from other organizations)

5 – Marine Omega‐3 Supplementation and Cardiovascular Disease: An Updated Meta‐Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants – Journal of the American Heart Association (free)

Commentaries: Omega-3 fish oil supplements linked with lower cardiovascular disease risk – Harvard T.H. Chan School of Public Health (free) AND Latest fish oil analysis suggests omega-3s promote heart health – Cardiovascular Business (free)

6 – Cochrane Handbook for Systematic Reviews of Interventions – Version 6, 2019 – Cochrane Library (free chapters)

Cochrane News Releases: New Cochrane Handbook for Systematic Reviews of Interventions (free) What you need to know about the new Cochrane Handbook (free)

7 – Pathology of Vaping-Associated Lung Injury – New England Journal of Medicine (free)

Commentaries: Vaping-related lung injuries resemble chemical burns, study finds – STAT (free) AND U.S. doctors rule out pneumonia due to inhaled oil as cause of vaping injuries – Reuters (free) AND Lung Damage From Vaping Resembles Chemical Burns, Report Says – The New York Times (10 articles per month are free)

8 – Editor’s Choice – Overview of Primary and Secondary Analyses From 20 Randomised Controlled Trials Comparing Carotid Artery Stenting With Carotid Endarterectomy – European Journal of Vascular & Endovascular Surgery (free)

9 – Antidepressant use during pregnancy and the risk of gestational diabetes mellitus: a nested case–control study – BMJ Open (free)

Commentaries: Antidepressants linked to heightened pregnancy related diabetes risk – BMJ (free) AND Antidepressants linked to risk of gestational diabetes – OnMedica (free) AND Antidepressants are linked to a higher gestational diabetes risk in a new study – CNN (free)

10 – Association of Antidepressant Use With Adverse Health Outcomes: A Systematic Umbrella Review – JAMA Psychiatry (free for a limited period)

Editorial: Selective Serotonin Reuptake Inhibitor Use During Pregnancy—Associated With but Not Causative of Autism in Offspring (free for a limited period)

Commentaries: Antidepressant medications appear to be generally safe,study suggests – Linköping University (free) AND Expert reaction to study on association of antidepressant use with adverse health outcomes – Science Media Centre (free)

Wed October 2 – 10 Stories of The Day!

2 Oct, 2019 | 10:19h | UTC

1 – Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America – American Journal of Respiratory and Critical Care Medicine (free)

News Release: ATS/IDSA publishes clinical guideline on community acquired pneumonia – American Thoracic Society (free)

See also: Executive Summary (free PDF)

2 – Healthy Dietary Patterns and Incidence of CKD: A Meta-Analysis of Cohort Studies – Clinical Journal of the American Society of Nephrology (free)

Commentaries: A healthy diet may help prevent kidney disease – American Society of Nephrology (free) AND Healthy Diet May Prevent CKD, Albuminuria – Renal & Urology News (free) AND Patient Voice: Diet Patterns and Kidney Disease – Clinical Journal of the American Society of Nephrology (free)

3 – Special Issue: Obstetric Anaesthesia – Update in Anaesthesia (free articles)

– Homepage

– Obstetric anaesthesia in resource limited settings

– Obstetric airway management

– General anesthesia for elective cesarean section in resource-limited settings

– Obstetric spinal anaesthesia

– Management of total spinal block in obstetrics

– Labour epidural the basics

– Labour epidural troubleshooting

– Establishing an epidural service for labour analgesia in a variable resource environment

– Emergency management of maternal collapse and arrest

– Pre-eclampsia – prevention, diagnosis and management

– Placental pathology: a review of placenta previa, placental abruption and placenta accreta

– Anaesthetic implications of morbid obesity in pregnancy

– Update in obstetric trauma management

– Update in obstetric maternal sepsis

– Oxytocics

– Obstetric and foetal physiology

– Newborn resuscitation

– Anaesthesia for non obstetric surgery during pregnancy

Source: Critical Care Reviews Newsletter

4 – Chronic Kidney Disease Diagnosis and Management: A Review – JAMA (free for a limited period)

5 – Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Is High-Dose Vitamin C Beneficial for Patients With Sepsis? (free)

Commentary: ‘Tantalizing’ Results For A Test Of Vitamin C For Sepsis – NPR (free)

In exploratory analyses that did not adjust for multiple comparisons, 3 secondary outcomes (out of 46 examined) were significantly different between groups. At day 28, mortality was 46.3% (38/82) in the placebo group vs 29.8% (25/84) in the vitamin C group (P = .03). The number of ICU-free days to day 28 was 10.7 in the vitamin C group vs 7.7 in the placebo group (P = .03). The number of hospital-free days in the vitamin C group vs the placebo group was 22.6 vs 15.5, respectively (P = .04)

6 – Meat’s Bad for You! No, It’s Not! How Experts See Different Things in the Data – The New York Times (10 articles per month are free)

Original Article: Guideline: It Is NOT Necessary to Reduce Red and Processed Meat Consumption (free guideline and commentaries)

7 – Cool Running Water First Aid Decreases Skin Grafting Requirements in Pediatric Burns: A Cohort Study of Two Thousand Four Hundred Ninety-five Children – Annals of Emergency Medicine (link to abstract – $ for full-text)

Commentary: Simple Cool Running Water Reduces Burn Severity in Children – Journal Feed (free)

8 – Smoking reduction interventions for smoking cessation – Cochrane Library (free)

Summary: Can people stop smoking by cutting down the amount they smoke first? – Cochrane Library (free)

9 – Long-term outcomes of childhood sexual abuse: an umbrella review – The Lancet Psychiatry (free)

Commentaries: Understanding and responding to the long-term burdens of childhood sexual abuse – The Lancet Psychiatry (free) AND Childhood sexual abuse linked to a range of physical and mental health conditions – University of Oxford (free)

10 – Single inhaler extrafine triple therapy in uncontrolled asthma (TRIMARAN and TRIGGER): two double-blind, parallel-group, randomised, controlled phase 3 trials – The Lancet (link to abstract – $ for full-text)

Commentaries: Asthma 3-in-1 Therapy May Improve Lung Function, Study Shows – The New York Times (10 articles per month are free) AND Triple-Therapy Inhaler Tied to Better Lung Function in Asthma – NEJM Journal Watch (free)

Tue October 1 – 10 Stories of The Day!

1 Oct, 2019 | 01:36h | UTC

1 – Unprocessed Red Meat and Processed Meat Consumption: Dietary Guideline Recommendations From the Nutritional Recommendations (NutriRECS) Consortium – Annals of Internal Medicine (free)

Editorial: Meat Consumption and Health: Food for Thought (free)

Commentaries: Eat Less Red Meat, Scientists Said. Now Some Believe That Was Bad Advice. – The New York Times (10 articles per month are free) AND Red and processed meat are OK to eat, controversial new guidelines claim. Don’t believe it, leading experts say – CNN (free) AND Expert reaction to new papers looking at red and processed meat consumption and health – Science Media Centre (free)

2 – Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents – Pediatrics (free)

News Release: Updated ADHD guideline addresses evaluation, diagnosis, treatment from ages 4-18 – American Academy of Pediatrics (free)

Commentary: Pediatricians Stand By Meds For ADHD, But Some Say Therapy Should Come First – NPR (free)

3 – State of the Art Review: What are the respiratory effects of e-cigarettes? – The BMJ (free for a limited period)

4 – Chronic Kidney Disease and Coronary Artery Disease: State-of-the-Art Review – Journal of the American College of Cardiology (free for a limited period)

Key Points to Remember: Chronic Kidney Disease and Coronary Artery Disease (free)

5 – Top 10 evidence-based recommendations from the Brazilian Society of Infectious Diseases for the Choosing Wisely Project – The Brazilian Journal of Infectious Diseases (free)

See other Choosing Wisely recommendations in infectious diseases: Infectious Diseases Society of America / American Academy of Pediatrics – Committee on Infectious Diseases and the Pediatric Infectious Diseases Society / Australasian Society for Infectious Diseases / Association of Medical Microbiology and Infectious Disease Canada

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

6 – Prednisolone Versus Dexamethasone for Croup: a Randomized Controlled Trial – Pediatrics (link to abstract – $ for full-text)

Commentaries: Steroids for Croup RCT – Dexamethasone or Prednisolone? – Journal Feed (free) AND Prednisolone and Dexamethasone Demonstrated Noninferiority in Childhood Croup – Pulmonology Advisor (free)

Related Systematic Review: Glucocorticoids for croup in children – Cochrane Library (free)

7 – Incidence and Determinants of Mental Health Service Use After Bariatric Surgery – JAMA Psychiatry (free for a limited period)

Commentaries: Patients more likely to seek psychiatric help after weight-loss surgery – Reuters (free) AND Mental health service use up after bariatric surgery – MedicalXpress (free)

8 – Prevention, assessment, diagnosis and management of diabetic foot based on clinical practice guidelines: A systematic review – Medicine (free)

9 – Racial/Ethnic Disparities in the Prevalence of Diabetes and Prediabetes by BMI: Patient Outcomes Research To Advance Learning (PORTAL) Multisite Cohort of Adults in the U.S. – Diabetes Care (link to abstract – $ for full-text)

Commentaries: Members of minority groups more likely to have diabetes at lower weights – News Medical (free) AND Rates of Diabetes Higher at Lower BMIs Among Minorities – Endocrinology Advisor (free) AND Minorities More Likely Than Whites to Have Diabetes at Normal BMI – Medscape (free registration required)

10 – Diagnosis of osteoporosis in statin-treated patients is dose-dependent – Annals of Rheumatic Diseases (free)

Commentary: Statins could increase or decrease osteoporosis risk — the dosage makes the difference – Complexity Science Hub Vienna (free)

Mon September 30 – 10 Stories of The Day!

30 Sep, 2019 | 01:31h | UTC

1 – Characteristics of a Multistate Outbreak of Lung Injury Associated with E-cigarette Use, or Vaping — United States, 2019 – Centers for Diseases Control and Prevention (free)

Commentaries: Many patients with vaping-related illnesses used THC, CDC reports – STAT (free) AND THC vape products may be the main culprit in the mysterious lung illness outbreak – Vox (free) AND U.S. CDC recommends against using vapes with marijuana ingredient – Reuters (free)

Related: Preliminary Report: Pulmonary Illness Related to E-Cigarette Use (free resources)

2 – Special Issue: Nutrition – ICU Management & Practice (free articles)

– Homepage

– Editorial by Prof. Jean-Louis Vincent, MD, PhD

– New ESPEN Guidelines for Nutrition in the Critically Ill: Help, What Happened!?

– New Trends in ICU Nutrition

– Emerging Concepts in Nutritional Therapy for the Critically Ill Child

– Obesity and Nutrition in Critical Illness

– Objective Malnutrition Diagnosis and Personalised Nutrition Delivery in the ICU

– The Role of Speech and Language Therapy Supporting Nutritional Management in ICU

Infographic: An overview of nutrition management in the ICU

3 – Novelist Cormac McCarthy’s tips on how to write a great science paper – Nature (free)

4 – Understanding acute burn injury as a chronic disease – Burns & Trauma (free)

5 – Five-Year Outcomes after PCI or CABG for Left Main Coronary Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: EXCEL at 5 Years: PCI for Left Main CAD Still Noninferior to CABG – TCTMD (free) AND EXCEL: No Significant Outcome Differences in PCI vs CABG for Left Main Coronary Disease at Five Years – American College of Cardiology (free)

6 – Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study – JAMA Oncology (free)

7 – The Effect of Abemaciclib Plus Fulvestrant on Overall Survival in Hormone Receptor–Positive, ERBB2-Negative Breast Cancer That Progressed on Endocrine Therapy—MONARCH 2: A Randomized Clinical Trial – JAMA Oncology (free)

Commentary: Two Studies Show CDK4/6 Inhibitors Improve Overall Survival in Advanced Breast Cancer [ESMO 2019 Press Release] (free)

#ESMO19 – Just presented at the European Society of Medical Oncology Congress 2019 in Barcelona

8 – Men with Prostate Cancer can be Spared Radiotherapy after Surgery [ESMO 2019 Press Release] (free)

#ESMO19 – Just presented at the European Society of Medical Oncology Congress 2019 in Barcelona

9 – Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Skin cancer: Half of people surviving advanced melanoma – BBC (free) AND Combination immunotherapy drugs herald new hope for melanoma patients with long term survival rates – The Royal Marsden NHS Foundation Trust (free)

#ESMO19 – Just presented at the European Society of Medical Oncology Congress 2019 in Barcelona

10 – Nivolumab plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Two immunotherapy drug combination offers chemotherapy-free option for advanced NSCLC – European Society for Medical Oncology (free) AND Nivolumab/Low-dose Ipilimumab: A Potential Chemotherapy-Sparing Option in Advanced NSCLC – Pharmacy Times (free)

#ESMO19 – Just presented at the European Society of Medical Oncology Congress 2019 in Barcelona

Fri September 27 – 10 Stories of The Day!

27 Sep, 2019 | 08:36h | UTC

1 – Diagnosis and management of Guillain–Barré syndrome in ten steps – Nature Reviews Neurology (free)

2 – Should antidepressants be used for major depressive disorder? – BMJ Evidence-Based Medicine (free)

Related Commentary: Do Antidepressants Work? – The New York Times (10 articles per month are free)

“Generally, all the previous reviews show that antidepressants seem to have statistically significant effects on depressive symptoms, but the size of the effect has questionable importance to most patients.”

3 – Clinical Approach to Lactose Intolerance – JAMA (free for a limited period)

4 – Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing non‐cardiac surgery – Cochrane Library (free)

Summary: Beta-blockers to prevent death or serious events after surgery not involving the heart – Cochrane Library (free)

5 – Over-the-Counter Access to Hormonal Contraception – American College of Obstetricians and Gynecologists (free)

Summary: Over-the-Counter Access to Hormonal Contraception (free)

News Release: ACOG Updates Guidance on Over-the-Counter Access to Hormonal Contraception (free)

Commentaries: Hormonal Contraceptives Should Be Available OTC, ACOG Recommends – NEJM Journal Watch (free) AND All hormonal birth control should be available over the counter, OB-GYN group says – NBC News (free)

6 – Total Hip Arthroplasty or Hemiarthroplasty for Hip Fracture – New England Journal of Medicine (free)

Commentary: International study finds similar results from total or partial hip replacement – McMaster University (free)

7 – Ticagrelor with or without Aspirin in High-Risk Patients after PCI – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Ticagrelor With Aspirin or Alone in High-Risk Patients After Coronary Intervention – TWILIGHT – American College of Cardiology (free) AND TWILIGHT: Ticagrelor Monotherapy Lowers Bleeding Without Increasing Ischemic Events – TCTMD (free)

8 – Association of BCG Vaccination in Childhood With Subsequent Cancer Diagnoses: A 60-Year Follow-up of a Clinical Trial – JAMA Network Open (free)

Commentaries: BCG Vaccination and Cancer Risk: What’s the Link? – MPR (free) AND BCG Vax: A Shot Against Lung Cancer in Native Populations? – MedPage Today (free)

9 – This is how attitudes to vaccines compare around the world – World Economic Forum (free)

10 – Effect of Organization-Directed Workplace Interventions on Physician Burnout: A Systematic Review – Mayo Clinic Proceedings: Innovations, Quality & Outcomes (free)

Related: Physician Burnout: A Global Crisis (several resources on the subject)

Thu September 26 – 10 Stories of The Day!

26 Sep, 2019 | 10:44h | UTC

1 – A comparison of deep learning performance against health-care professionals in detecting diseases from medical imaging: a systematic review and meta-analysis – The Lancet Digital Health (free)

Commentaries: Human versus machine in medicine: can scientific literature answer the question? – The Lancet Digital Health (free) AND First systematic review and meta-analysis suggests artificial intelligence may be as effective as health professionals at diagnosing disease – The Lancet (free) AND Can AI really interpret images as well as physicians? – Health Imaging (free) AND Expert reaction to a study looking at the effectiveness of AI at diagnosing disease compared to health professionals – Science Media Centre (free)

2 – Planned mode of delivery after previous cesarean section and short-term maternal and perinatal outcomes: A population-based record linkage cohort study in Scotland – PLOS Medicine (free)

Commentaries: Outcomes of birth options after a previous Cesarean section – PLOS (free) AND Repeat C-sections safer option for some women – OnMedica (free)

3 – State of the clinical science of perioperative brain health: report from the American Society of Anesthesiologists Brain Health Initiative Summit 2018 – British Journal of Anaesthesia (free)

4 – Injectable opioid agonist treatment for opioid use disorder: a national clinical guideline – Canadian Medical Association Journal (free)

Commentaries: First-of-its-kind guideline sets out best practices for delivering injectable opioid agonist treatment – The University of British Columbia (free) AND New national guideline sets out best practices for delivering injectable opioid agonist treatment – Canadian Medical Association Journal (free)

5 – European Society for Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2019 – Journal of Pediatric Gastroenterology and Nutrition (free PDF)

6 – Efficacy of Neurohormonal Therapies in Preventing Cardiotoxicity in Patients With Cancer Undergoing Chemotherapy – JACC CardioOncology (free)

7 – Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Study assesses asthma treatment options in African American children and adults – NIH News Release (free)

8 – Alex Nowbar’s journal review, 24 September 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

9 – Changes in nut consumption influence long-term weight change in US men and women – BMJ Nutrition, Prevention & Health (free)

Commentaries: Boosting daily nut consumption linked to less weight gain and lower obesity risk – The BMJ (free) AND Higher daily nut consumption linked to lower weight gain – OnMedica (free) AND Eating more nuts may help prevent weight gain – Medical News Today (free)

10 – High-Intensity Versus Low-Intensity Surveillance for Patients With Colorectal Adenomas: A Cost-Effectiveness Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Model supports high-intensity surveillance after detection of colorectal adenomas – ACP Internist (free) AND High-intensity surveillance colonoscopy reduces CRC risk, is cost-effective for patients with colorectal adenomas – American College of Physicians (free)

Wed September 25 – 10 Stories of The Day!

25 Sep, 2019 | 10:35h | UTC

1 – Final Recommendation Statement: Screening for Asymptomatic Bacteriuria in Adults – U.S. Preventive Services Task Force (free)

Editorials: Updated Guidelines for Screening for Asymptomatic Bacteriuria (free) AND The 2019 USPSTF Report on Screening for Asymptomatic Bacteriuria—Lessons From History (free)

Author Interview: USPSTF Recommendation: Screening for Asymptomatic Bacteriuria in Adults (free audio)

2 – Guideline Synopsis: Prevention and Management of Venous Thromboembolism – JAMA (free for a limited period)

Clinical Review Audio: An Update on the Diagnosis and Treatment of Venous Thromboembolic Disease (free)

Original American Society of Hematology 2018 Guidelines: Prophylaxis for hospitalized and nonhospitalized medical patients (free) AND Diagnosis of venous thromboembolism (free) AND Optimal management of anticoagulation therapy (free) AND Treatment of pediatric venous thromboembolism (free) AND Venous thromboembolism in the context of pregnancy (free) AND Heparin-induced thrombocytopenia (free)

3 – Withholding and withdrawing life-support in adults in emergency care: joint position paper from the French Intensive Care Society and French Society of Emergency Medicine – Annals of Intensive Care (free)

4 – Injury Risk Associated with Sports Specialization and Activity Volume in Youth – Orthopaedic Journal of Sports Medicine (free)

Commentaries: For young athletes, sport specialization means increased risk of injury – Brown University (free) AND Sports Specialization Hurts Girls More Than Boys – MedicalResearch.com (free)

Related Meta-Analysis: Sport Specialization and Risk of Overuse Injuries (link to abstract and commentary)

5 – Effects of antihypertensives, lipid-modifying drugs, glycaemic control drugs and sodium bicarbonate on the progression of stages 3 and 4 chronic kidney disease in adults: a systematic review and meta-analysis – BMJ Open (free)

6 – A Simple Regimen Can Prevent TB. Why Aren’t More People on It? – The New York Times (10 articles per month are free)

7 – Age to stop? Appropriate screening in older patients – Canadian Family Physician (free)

Editorial: Preventive care at both ends of life (free)

Podcast: Appropriate screening in older patients (free audio)

Source: Canadian Task Force on Preventive Health Care Newsletter

8 – Finding the Right Words to Stop Cancer Screening in Older Adults – JAMA (free)

9 – Acute ischaemic stroke: challenges for the intensivist – Intensive Care Medicine (free)

Source: Critical Care Reviews Newsletter

10 – Inherited Thrombophilia and the Risk of Arterial Ischemic Stroke: A Systematic Review and Meta‐Analysis – Journal of the American Heart Association (free)

Tue September 24 – 10 Stories of The Day!

24 Sep, 2019 | 10:30h | UTC

1 – School-aged Children Who Are Not Progressing Academically: Considerations for Pediatricians – Pediatrics (free)

News Release: Report guides pediatricians in evaluating children with academic problems – American Academy of Pediatrics (free)

Commentary: Pediatrics Group Offers Guidance for Supporting Children who Struggle in School – NEJM Journal Watch (free)

2 – Expert panel consensus recommendations for ambulatory blood pressure monitoring in Asia: The HOPE Asia Network – The Journal of Clinical Hypertension (free)

3 – Chronic kidney disease and valvular heart disease: conclusions from Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference – Kidney International (free)

4 – Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C Virus Infection in Chronic Kidney Disease: Synopsis of the Kidney Disease: Improving Global Outcomes 2018 Clinical Practice Guideline – Annals of Internal Medicine (free)

Original Guideline: KDIGO 2018 Clinical Practice Guideline for the Prevention, Diagnosis, Evaluation, and Treatment of Hepatitis C in Chronic Kidney Disease – Kidney International (free)

5 – Association of Relative Age in the School Year With Diagnosis of Intellectual Disability, Attention-Deficit/Hyperactivity Disorder, and Depression – JAMA Pediatrics (free)

Commentaries: Youngest children in school year could be at higher risk of mental health problems – London School of Hygiene & Tropical Medicine (free) AND Expert reaction to relative age in school year, and diagnosis of intellectual disability, depression and ADHD – Science Media Centre (free)

Related: Study: Youngest in Class More Likely to be Diagnosed with ADHD (link to abstract and commentaries) AND Systematic Review: Youngest in Class More Likely to be Diagnosed with ADHD (free study and commentaries)

6 – Association Between Screen Media Use and Academic Performance Among Children and Adolescents: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a limited period)

Commentaries: Expert reaction to screen media use and academic performance – Science Media Centre (free) AND Not all screen time causes kids to underperform in school, study says – CNN (free)

7 – #174 Dominate Perioperative Medication Management – The Curbsiders Internal Medicine Podcast (free)

Related Episode: #135 Perioperative Medicine: Assess & Optimize Risk (free)

See also: Episode List

8 – Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing cardiac surgery – Cochrane Library (free)

Summary: Beta-blockers to prevent death or serious events after heart surgery – Cochrane Library (free)

Related: Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity – Cochrane Library (free)

9 – Non‐steroidal anti‐inflammatory drugs for heavy menstrual bleeding – Cochrane Library (free)

Summary: Are non-steroidal anti-inflammatory drugs safe and effective for treating heavy menstrual bleeding? – Cochrane Library (free)

10 – Rate and Prognosis of Brain Ischemia in Patients With Lower-Risk Transient or Persistent Minor Neurologic Events – JAMA Neurology (free for a limited period)

Editorial: Benefits of Magnetic Resonance Imaging for Patients Presenting With Low-risk Transient or Persistent Minor Neurologic Deficits (free)

Commentaries: MRI can help clinicians diagnose minor stroke – HealthImaging (free) AND Study highlights importance of MRI in helping diagnose minor strokes – News Medical (free)

Author Interview: Rate and Prognosis of Brain Ischemia in Lower-Risk Transient or Persistent Minor Neurologic Events (free)

Mon September 23 – 10 Stories of The Day!

23 Sep, 2019 | 01:39h | UTC

1 – UNICEF News Release: Surviving birth: Every 11 seconds, a pregnant woman or newborn dies somewhere around the world (free)

WHO News Release: More women and children survive today than ever before – World Health Organization (free)

Reports: Maternal mortality: Levels and trends 2000 to 2017 – WHO, UNICEF, UNFPA, World Bank Group and the United Nations Population Division (free PDF) AND Levels and trends in child mortality report 2019: Estimates developed by the UN Inter-agency Group for Child Mortality Estimation – UNICEF, WHO, World Bank, UN-DESA Population Division (free PDF)

WHO Updated Fact Sheets: Newborns: reducing mortality (free) AND Children: reducing mortality (free) AND Maternal mortality (free)

2 – Diagnosis of chronic anaemia in gastrointestinal disorders: A guideline by the Italian Association of Hospital Gastroenterologists and Endoscopists (AIGO) and the Italian Society of Paediatric Gastroenterology Hepatology and Nutrition (SIGENP) (free)

3 – The management of unanticipated difficult airways in children of all age groups in anaesthetic practice – the position paper of an expert panel – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)

Related: Guideline: Management of the Child’s Airway Under Anesthesia (free guidelines) AND Review: Difficult Airway Management Algorithms (free guidelines)

4 – The clinical effectiveness of sertraline in primary care and the role of depression severity and duration (PANDA): a pragmatic, double-blind, placebo-controlled randomised trial – The Lancet Psychiatry (free)

Commentaries: Examining the antidepressant scattergun approach – The Lancet Psychiatry (free) AND Expert reaction to study on the clinical effectiveness of the antidepressant sertraline – Science Media Centre (free) AND Common antidepressant more effective for anxiety than depression – UPI (free) AND Antidepressants work, but just not how scientists thought they worked – The Conversation (free) AND Antidepressants may reduce anxiety more than depressive symptoms – University College London (free)

5 – Population Impact Attributable to Modifiable Risk Factors for Hyperuricemia – Arthritis & Rheumatology (free)

Commentaries: Obesity, drinking and unhealthy diet add to gout risk – Reuters (free) AND Four Modifiable Risk Factors Tied to Hyperuricemia – HealthDay News (free)

6 – Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes – Cochrane Library (free)

Summary: Does delaying cord clamping or using cord milking at birth improve the health of babies born too early? – Cochrane Library (free)

7 – Association of Prenatal Maternal Anemia With Neurodevelopmental Disorders – JAMA Psychiatry (free)

Commentary: Early maternal anemia tied to intellectual disability, ADHD and autism – Karolinska Institutet (free) AND Anemia in Early Pregnancy May Harm Child Neurodevelopment – Clinical Advisor (free) AND Anemia in early pregnancy linked with risk for neurodevelopmental disorders – Reuters (free)

8 – Long-term immunity against yellow fever in children vaccinated during infancy: a longitudinal cohort study – The Lancet Infectious Diseases (free)

Commentaries: Are booster doses of yellow fever vaccine needed? – The Lancet Infectious Diseases (free) AND A single dose of yellow fever vaccine does not offer lasting protection to all children – MedicalXpress (free)

9 – Immunogenicity, effectiveness, and safety of measles vaccination in infants younger than 9 months: a systematic review and meta-analysis – The Lancet Infectious Diseases (free)

Invited Commentary: Early vaccination: a provisional measure to prevent measles in infants (free)

10 – Nicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation: a pragmatic, randomised trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

Commentary: Quick Take: Nicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation – 2 Minute Medicine (free)

Fri September 20 – 10 Stories of The Day!

20 Sep, 2019 | 08:48h | UTC

1 – Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction – New England Journal of Medicine (link to abstract – $ for full-text)

Related 2019 ESC Congress News Release, Before Publication: Randomized Trial: SGLT2 inhibitors Seems Beneficial for Heart Failure Even in Nondiabetics (free commentaries)

Commentaries: SGLT2 Inhibitor Dapagliflozin Lowers Risk for Worsening Heart Failure – NEJM Journal Watch (free) AND New research shows dapagliflozin used to treat diabetes can also treat heart failure, in patients with and without diabetes (the DAPA-HF Study) – Diabetologia (free)

2 – VA/DoD Clinical Practice Guideline: Diagnosis and Treatment of Low Back Pain – Journal of General Internal Medicine (free)

Source: Low back pain: joint guidelines from US Departments of Veterans Affairs, Defense – Univadis (free registration required)

3 – Association of Early Palliative Care Use With Survival and Place of Death Among Patients With Advanced Lung Cancer Receiving Care in the Veterans Health Administration – JAMA Oncology (free for a limited period)

Editorial: Prolonged Survival With Palliative Care—It Is Possible, but Is It Necessary? (free)

Commentaries: Early Palliative Care Associated with Increased Survival in Lung Cancer Patients – MedicalResearch.com (free) AND Early palliative care for advanced lung cancer increases survival – Veterans Affairs Research Communications (free)

Related Systematic Review: Early palliative care for adults with advanced cancer – Cochrane Library (free summary and original article)

4 – Association of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function – JAMA (free for a limited period)

Commentaries: Metformin Superior for Lowering CV Risk in Diabetics Who Progress to CKD – Renal & Urology News (free) AND Metformin Monotherapy Benefits Heart Even in Early CKD – MedPage Today (free registration required)

5 – Effect of Linagliptin vs Glimepiride on Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes: The CAROLINA Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Sulfonylureas and Cardiovascular Safety: The Final Verdict? – JAMA (free for a limited period)

Commentary: CAROLINA: No Added Heart Risk With Sulfonylureas – MedPage Today (free registration required)

6 – Preoxygenation before intubation in adult patients with acute hypoxemic respiratory failure: a network meta-analysis of randomized trials – Critical Care (free) (via Park M, MD)

7 – Metabolic support in the critically ill: a consensus of 19 – Critical Care (free) (via Park M, MD)

8 – Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Meta-Analysis of TAVR vs. SAVR in Low-Risk Patients – American College of Cardiology (free) AND TAVR Survival Surpasses SAVR in Low-Risk Patients: Meta-analysis – Medscape (free registration required)

“The one clear unknown that everyone points to is valve durability” (form Medscape)

“longer follow-up regarding valve degeneration will be needed to confirm TAVR as the preferred treatment for low-risk patients with severe AS.” (from American College of Cardiology)

9 – Cochrane Special Collection: Diagnosing Dementia – Cochrane Library (free articles)

Commentary: Dementia diagnosis: a decade of evidence – Evidently Cochrane (free)

10 – News Release: AAN Recommends People 65+ be Screened Yearly for Memory Problems – American Academy of Neurology (free)

Original Recommendations: Quality improvement in neurology: Mild cognitive impairment quality measurement set – American Academy of Neurology (free PDF)

USPSTF Disagrees: USPSTF Draft Statement: Insufficient Evidence to Recommend Screening for Cognitive Impairment in Older Adults (free)