Wed September 18 – 10 Stories of The Day!

1 – Updated good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults and children in the UK – JAC-Antimicrobial Resistance (free)

Commentary: Outpatient parenteral antimicrobial therapy: updated recommendations from the UK – Journal of Antimicrobial Chemotherapy (free)

Related: IDSA Guideline: Management of Outpatient Parenteral Antimicrobial Therapy (free)

2 – Blood Culture Results Before and After Antimicrobial Administration in Patients with Severe Manifestations of Sepsis: A Diagnostic Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Initiating empirical therapy for sepsis reduces blood culture sensitivity – MedicalXpress (free) AND Study changes guidelines for sepsis management – University of Arizona College of Medicine (free)

3 – Personalized Prediction of Cardiovascular Benefits and Bleeding Harms From Aspirin for Primary Prevention: A Benefit–Harm Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Aspirin may benefit some people without cardiovascular disease, new analysis finds – ACP Internist (free) AND Some Adults Without Heart Disease May Benefit From Aspirin – MedicalResearch.com (free) AND Expert reaction to study looking at benefits and harms of aspirin in people without cardiovascular disease – Science Media Centre (free)

4 – Effect of Vaginal Mesh Hysteropexy vs Vaginal Hysterectomy With Uterosacral Ligament Suspension on Treatment Failure in Women With Uterovaginal Prolapse: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Pelvic Organ Prolapse: Reconsidering Treatment, Innovation, and Failure (free)

Commentaries: Mesh implants have similar outcomes to hysterectomy for vaginal prolapse repair – NIH News Releases (free) AND Hysterectomy and Mesh Support May Have Similar Outcomes in Repairing Vaginal Prolapse – University of California San Diego Health (free)

5 – Effect of Behavioral and Pelvic Floor Muscle Therapy Combined With Surgery vs Surgery Alone on Incontinence Symptoms Among Women With Mixed Urinary Incontinence: The ESTEEM Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Evidence-Based Treatment for Mixed Urinary Incontinence (free)

Commentaries: Surgery may benefit women with two types of urinary incontinence – NIH News Releases (free) AND Surgery Alone Can Improve Mixed Urinary Incontinence Symptoms – Renal & Urology News (free)

6 – Almost Everywhere, Fewer Children Are Dying – The New York Times (10 articles per month are free)

Original Report: The Goalkeepers Report 2019 (free)

Related: What are children dying from and what can we do about it? – Our World in Data (free)

7 – Helmet use and bicycle-related trauma injury outcomes – Brain Injury (free)

Commentary: More evidence supports helmet use by cyclists – Reuters (free) AND Most cyclists suffering head injuries not wearing helmets, study shows – HealthDay (free)

8 – AAOS Systematic Literature Review: Summary on the Management of Surgical Site Infections – JAAOS – Journal of the American Academy of Orthopaedic Surgeons (free)

Original Guideline: Management of Surgical Site Infections – American Academy of Orthopedic Surgeons (free) / Full Guideline (free PDF)

Source: Medscape

9 – What’s new in airway management of the critically ill – Intensive Care Medicine (free)

10 – Interventions for treating brain arteriovenous malformations in adults – Cochrane Library (free)

Summary: Interventions for treating abnormal tangles of blood vessels in the brain in adults – Cochrane Library (free)