Fri September 20 – 10 Stories of The Day!
20 Sep, 2019 | 08:48h | UTC
1 – Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction – New England Journal of Medicine (link to abstract – $ for full-text)
Related 2019 ESC Congress News Release, Before Publication: Randomized Trial: SGLT2 inhibitors Seems Beneficial for Heart Failure Even in Nondiabetics (free commentaries)
Commentaries: SGLT2 Inhibitor Dapagliflozin Lowers Risk for Worsening Heart Failure – NEJM Journal Watch (free) AND New research shows dapagliflozin used to treat diabetes can also treat heart failure, in patients with and without diabetes (the DAPA-HF Study) – Diabetologia (free)
Source: Low back pain: joint guidelines from US Departments of Veterans Affairs, Defense – Univadis (free registration required)
Related: Clinical practice guidelines for the management of non-specific low back pain in primary care: an updated overview – European Spine Journal (free) AND Clinical practice guidelines for the noninvasive management of low back pain: A systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration – European Journal of Pain (free) AND Low back pain and sciatica in over 16s: assessment and management – NICE (free) AND Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians (free) AND National Clinical Guidelines for non-surgical treatment of patients with recent onset low back pain or lumbar radiculopathy – European Spine Journal (free)
3 – Association of Early Palliative Care Use With Survival and Place of Death Among Patients With Advanced Lung Cancer Receiving Care in the Veterans Health Administration – JAMA Oncology (free for a limited period)
Editorial: Prolonged Survival With Palliative Care—It Is Possible, but Is It Necessary? (free)
Commentaries: Early Palliative Care Associated with Increased Survival in Lung Cancer Patients – MedicalResearch.com (free) AND Early palliative care for advanced lung cancer increases survival – Veterans Affairs Research Communications (free)
Related Systematic Review: Early palliative care for adults with advanced cancer – Cochrane Library (free summary and original article)
Related Guidelines: Integration of Palliative Care Into Standard Oncology Care: American Society of Clinical Oncology Clinical Practice Guideline Update (free) AND Consensus document of the Italian Association of Medical Oncology and the Italian Society of Palliative Care on early palliative care – Tumori Journal (free)
Related Video: Early Palliative Care: a video for health and care professionals – University of Edinburgh (free)
Related Randomized Trial: Early Palliative Care for Patients with Metastatic Non–Small-Cell Lung Cancer- New England Journal of Medicine (free)
4 – Association of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function – JAMA (free for a limited period)
Commentaries: Metformin Superior for Lowering CV Risk in Diabetics Who Progress to CKD – Renal & Urology News (free) AND Metformin Monotherapy Benefits Heart Even in Early CKD – MedPage Today (free registration required)
5 – Effect of Linagliptin vs Glimepiride on Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes: The CAROLINA Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Sulfonylureas and Cardiovascular Safety: The Final Verdict? – JAMA (free for a limited period)
Commentary: CAROLINA: No Added Heart Risk With Sulfonylureas – MedPage Today (free registration required)
6 – Preoxygenation before intubation in adult patients with acute hypoxemic respiratory failure: a network meta-analysis of randomized trials – Critical Care (free) (via Park M, MD)
7 – Metabolic support in the critically ill: a consensus of 19 – Critical Care (free) (via Park M, MD)
8 – Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Meta-Analysis of TAVR vs. SAVR in Low-Risk Patients – American College of Cardiology (free) AND TAVR Survival Surpasses SAVR in Low-Risk Patients: Meta-analysis – Medscape (free registration required)
“The one clear unknown that everyone points to is valve durability” (form Medscape)
“longer follow-up regarding valve degeneration will be needed to confirm TAVR as the preferred treatment for low-risk patients with severe AS.” (from American College of Cardiology)
9 – Cochrane Special Collection: Diagnosing Dementia – Cochrane Library (free articles)
Commentary: Dementia diagnosis: a decade of evidence – Evidently Cochrane (free)
10 – News Release: AAN Recommends People 65+ be Screened Yearly for Memory Problems – American Academy of Neurology (free)
Original Recommendations: Quality improvement in neurology: Mild cognitive impairment quality measurement set – American Academy of Neurology (free PDF)
USPSTF Disagrees: USPSTF Draft Statement: Insufficient Evidence to Recommend Screening for Cognitive Impairment in Older Adults (free)