TOP 10 Medical News Stories
Mon, February 18 – 10 Stories of The Day!
18 Feb, 2019 | 00:01h | UTC
News Release: AASM publishes clinical practice guideline on use of PAP therapy for sleep apnea (free)
Related Podcast: Sleep Apnea Pearls and Pitfalls (free)
Related Guideline: 2018 ESC/EACTS Guidelines on myocardial revascularization – European Heart Journal (free)
3 – Homepage: FIGO Working Group on Good Clinical Practice in Maternal–Fetal Medicine – International Journal of Gynecology & Obstetrics (free articles)
– Good clinical practice advice: Micronutrients in the periconceptional period and pregnancy
– Good clinical practice advice: Iron deficiency anemia in pregnancy
– Good clinical practice advice: Management of twin pregnancy
– Good clinical practice advice: Role of ultrasound in the management of twin pregnancy
– Good clinical practice advice: Thyroid and pregnancy
– Good clinical practice advice: Antenatal corticosteroids for fetal lung maturation
4 – Managing malignant pleural effusion – Cleveland Clinic Journal of Medicine (free)
Related Guidelines: Management of Malignant Pleural Effusions. An Official ATS/STS/STR Clinical Practice Guideline – American Journal of Respiratory and Critical Care Medicine (free) AND ERS/EACTS statement on the management of malignant pleural effusions – European Respiratory Journal (free)
5 – Dialysis Is a Way of Life for Many Older Patients. Maybe It Shouldn’t Be – The New York Times (10 articles per month are free)
Related: Editorial: Prioritizing Patient and Caregiver Values in the Delivery of High-Quality Medical Management Without Dialysis (free)
“So-called conservative management can ease symptoms without dialysis in some people with kidney disease. But many of them are never given the option.”
News Release: New recommendations published: screening intervals and more (free)
Commentaries: Survival of total hip replacements – The Lancet (free) AND Longevity of hip, knee replacements in OA patients estimated – medwire News (free) AND Most hip and knee replacements ‘last longer than thought’ – BBC News (free)
10 – Homepage: Special Issue: Spinal Infections: From Prevention to Cure – Global Spine Journal (free articles)
– Surgical Site Infections in Spine Surgery: Preoperative Prevention Strategies to Minimize Risk
– Postoperative Spine Infection: Diagnosis and Management
– Risk Factors and Prevention of Surgical Site Infections Following Spinal Procedures
– Etiology and Surgical Management of Cervical Spinal Epidural Abscess (SEA):: A Systematic Review
– Thoracic Epidural Abscesses: A Systematic Review
– Lumbar Epidural Abscesses: A Systematic Review
– Spinal Tuberculosis: Current Concepts
Fri, February 15 – 10 Stories of The Day!
15 Feb, 2019 | 01:23h | UTC
1 – Computer vs. patient: Fighting for residents’ attention – SCOPE (free)
Original Article: Characterizing electronic health record usage patterns of inpatient medicine residents using event log data – PLOS One (free)
Related: Putting Patients First by Reducing Administrative Tasks in Health Care: A Position Paper of the American College of Physicians (free) AND Date Night with the EHR – NEJM Catalyst (free) AND How Tech Can Turn Doctors into Clerical Workers – The New York Times Magazine (10 articles per month are free) AND To Combat Physician Burnout and Improve Care, Fix the Electronic Health Record – Harvard Business Review (a few articles per month are free) AND “It is like texting at the dinner table”: a qualitative analysis of the impact of electronic health records on patient–physician interaction in hospitals – Journal of Innovation in Health Informatics (free) AND A Time-Motion Study of Primary Care Physicians’ Work in the Electronic Health Record Era – Family Medicine (free) AND Care-Centered Clinical Documentation in the Digital Environment: Solutions to Alleviate Burnout – National Academy of Medicine (free) AND Electronic Health Record Usability Issues and Potential Contribution to Patient Harm – JAMA (free)
2 – Head to Head: Should we screen for atrial fibrillation? – The BMJ (free)
Commentary: Should we screen people for irregular heartbeat? – The BMJ, via ScienceDaily (free)
Related: USPSTF Statement: Screening with Resting or Exercise Electrocardiography (ECG) Not Recommended (free Guideline and commentaries) AND Wearable technology to screen for atrial fibrillation: does it raise more questions than it answers? (free commentaries) AND Get Ready For A Tsunami Of ECGs (free commentaries)
Related Cochrane Review (just published): Pregabalin for neuropathic pain in adults – Cochrane Library (free) and Commentary: Pregabalin for neuropathic pain: balancing benefits and harms – Evidently Cochrane (free)
4 – Guideline Synopsis: Diagnosis and Management of Infectious Diarrhea – JAMA (free)
Original Guideline: 2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea (free)
Related Guidelines: Guidelines for the prevention and treatment of travelers’ diarrhea: a graded expert panel report (free) AND Guidelines for the Investigation of Chronic Diarrhoea in Adults: British Society of Gastroenterology (free)
Related Report: Global Burden of Diarrhea (free report and commentaries)
5 – Next-Generation Sequencing of Infectious Pathogens – JAMA (free)
Related: Advanced Molecular Detection (AMD) – Centers for Disease Control and Prevention (free resources) AND Next Generation Sequencing of Infectious Pathogens in Public Health and Clinical Practice – JAMA (free podcast) AND Integrating Advanced Molecular Technologies into Public Health – Journal of Clinical Microbiology (free) AND Next-generation sequencing technologies and their application to the study and control of bacterial infections – Clinical Microbiology and Infection (free) AND Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis – Clinical Microbiology Reviews (free)
6 – Decolonization to Reduce Postdischarge Infection Risk among MRSA Carriers – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Study: At-home decolonization cuts MRSA, other infections – CIDRAP (free) AND Outpatient cleaning regimen cuts MRSA infection by a third – News Medical (free) AND Cleaning routine shows promise in curbing superbug infection – Associated Press (free)
Worth reading.
Related: Guideline: Deprescribing Benzodiazepines (free guideline and resources) AND Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
Commentaries: Diet drinks may be associated with strokes among post-menopausal women – American Heart Association (free) AND Post-menopausal women who drink diet soda have increased stroke risk – UPI (free) AND Artificially Sweetened Drinks Linked to Stroke, Heart Disease – NEJM Journal Watch (free)
10 – Association of Behavior in Boys From Low Socioeconomic Neighborhoods With Employment Earnings in Adulthood – JAMA Pediatrics (free for a limited period)
Commentaries: Inattention in Low-Income Boys Tied to Lesser Earnings in Adulthood – PsychCentral (free) AND Low-income boys’ inattention in kindergarten associated with lower earnings 30 years later – Carnegie Mellon University (free) AND Behavior at Age 6 May Predict Adult Income – The New York Times (10 articles per month are free)
Thu, February 14 – 10 Stories of The Day!
14 Feb, 2019 | 02:03h | UTC
Commentary: Absence of hypertension, overweight and smoking results in 9 disease-free years and prolonged life expectancy of 6 years – PACE-CME (free)
2 – Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Ibuprofen may be a ‘reasonable option’ for analgesia after hip replacement – medwire News (free) AND Acetaminophen Plus Ibuprofen Linked to Less Morphine Use After Hip Arthroplasty – NEJM Journal Watch (free) AND Paracetamol plus ibuprofen significantly reduces post-operative morphine use in total hip arthroplasty patients – 2 Minute Medicine (free)
3 – Does This Patient Have a Severe Snake Envenomation? The Rational Clinical Examination Systematic Review – JAMA Surgery (free for a limited period)
Related: Global Mapping of Vulnerability to Snakebite Envenoming (free study and commentaries) AND Why Are So Many People Still Dying from Snake Bites? (free) AND Snakebite finally makes a WHO list of top global health priorities (free) AND Snakebites Make The List Of ‘Neglected Tropical Diseases’ (free)
Commentary: Permissive hypotensive resuscitation in patients with traumatic hemorrhagic shock – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)
5 – Zackary Berger’s weekly research reviews, 13 February 2019 – The BMJ Opinion (free)
7 – Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood: A Systematic Review and Meta-analysis – JAMA Psychiatry (link to abstract – $ for full-text)
Commentaries: Expert reaction to cannabis use in adolescents and risk of depression, anxiety and suicidality – Science Media Centre (free) AND Increased depression and suicidal behavior risk for young cannabis users – McGill University Health Centre (free) AND Cannabis smoking in teenage years linked to adulthood depression – The Guardian (free) AND Teen cannabis use linked to higher risk of adolescent depression – Reuters (free)
8 – Breast cancer deaths averted over 3 decades – Cancer (free)
Commentaries: Treatment Advances Averted More Than Half a Million Breast Cancer Deaths Over 3 Decades – AJMC (free) AND Recent Decrease in Deaths Attributable to Breast Cancer in the United States – The ASCO Post (free)
9 – Association of Left Ventricular Ejection Fraction and Symptoms With Mortality After Elective Noncardiac Surgery Among Patients With Heart Failure – JAMA (link to abstract – $ for full-text)
Commentaries: Symptomatic and non-symptomatic heart failure associated with increased postoperative mortality in non-cardiac elective surgery – 2 Minute Medicine (free) AND LVEF, HF Symptoms, and Mortality After Surgery – American College of Cardiology (free)
10 – Association of dietary macronutrient composition and non-alcoholic fatty liver disease in an ageing population: the Rotterdam Study – Gut (link to abstract – $ for full-text)
Commentary: Eating lots of meat tied to higher risk of liver disease – Reuters (free) AND Diet Heavy in Meat Boosts NAFLD Risk – MedPage Today (free registration required)
Wed, February 13 – 10 Stories of The Day!
13 Feb, 2019 | 02:18h | UTC
1 – News Release: New WHO-ITU standard aims to prevent hearing loss among 1.1 billion young people – World Health Organization (free)
Report: Safe listening devices and systems: a WHO-ITU standard – World Health Organization and International Telecommunication Union (free PDF)
Toolkit: Toolkit for safe listening devices and systems – World Health Organization and International Telecommunication Union (free PDF)
Editorials: Implementing the USPSTF Recommendations on Prevention of Perinatal Depression—Opportunities and Challenges (free) AND Perinatal Depression: Recommendations for Prevention and the Challenges of Implementation (free)
Author Interview: USPSTF Recommendation: Interventions to Prevent Perinatal Depression (free audio)
Commentaries: Depression During and After Pregnancy Can Be Prevented, National Panel Says. Here’s How. – The New York Times (10 articles per month are free) AND To Prevent Pregnancy-Related Depression, At-Risk Women Advised To Get Counseling – NPR (free)
“The USPSTF recommends that clinicians provide or refer pregnant and postpartum persons who are at increased risk of perinatal depression to counseling interventions. (B recommendation)”
3 – Urine Sediment Examination in the Diagnosis and Management of Kidney Disease: Core Curriculum 2019 – American Journal of Kidney Diseases (free for a limited period)
Related Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)
Related Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)
5 – The Case of the Scientific Ruse – EMNerd (free)
“February 7th 2019 marked an auspicious day in the history of the NEJM and its relationship with the pharmaceutical industry.”
6 – Combined hormonal contraceptives for heavy menstrual bleeding – Cochrane Library (free)
Summary: Combined hormonal contraceptives for heavy menstrual bleeding – Cochrane Library (free)
7 – Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Intensive Blood Pressure Lowering With Intravenous Thrombectomy for Acute Ischemic Stroke Did Not Improve Functional Outcomes – Practical Neurology (free) AND Tighter BP Control No Better in Acute Stroke – MedPage Today (free registration required)
8 – Association Between Ultraprocessed Food Consumption and Risk of Mortality Among Middle-aged Adults in France – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Ultra-processed foods push death risk up by 14 percent, study says – UPI (free) AND Do ‘heavily processed’ foods increase the risk of an early death? – NHS Choices (free)
Commentaries: Study finds upsurge in ‘active surveillance’ for low-risk prostate cancer – Dana-Farber Cancer Institute (free) AND Prostate Cancer Active Surveillance Increasing in the US – Renal & Urology News (free) AND Conservative management of low-risk prostate cancer increasing in USA – medwire News (free) AND More men with low-risk prostate cancer are forgoing treatment, study finds – CNN (free)
Related Guidelines: Active Surveillance for the Management of Localized Prostate Cancer (Cancer Care Ontario Guideline): American Society of Clinical Oncology Clinical Practice Guideline Endorsement – Journal of Clinical Oncology (free) AND Active surveillance for the management of localized prostate cancer: Guideline recommendations – Canadian Urological Association Journal (free)
Related Randomized Trial: Radical Prostatectomy vs. Watchful Waiting in Prostate Cancer (link to abstract and commentaries)
Tue, February 12 – 10 Stories of The Day!
12 Feb, 2019 | 00:40h | UTC
1 – The Topol Review: Preparing the healthcare workforce to deliver the digital future – NHS Health Education England (free report and related resources)
News Release: New Guidelines for Venous Thromboembolism (free)
Related Guidelines: BTS Guideline: Outpatient Management of Pulmonary Embolism (free) AND ACEP Clinical Policy: Evaluation and Management of Suspected Acute Venous Thromboembolism (free) AND Evaluation of Patients With Suspected Acute Pulmonary Embolism: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians (free) AND 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism: The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC) (free)
Commentary: Inexpensive supplement for women increases infant birth size – NIH News Releases (free)
4 – Identifying and managing younger women at high risk of cardiovascular disease – Canadian Medical Association Journal (free for 7 days)
Related Review: Knowledge, Attitudes, and Beliefs Regarding Cardiovascular Disease in Women: The Women’s Heart Alliance – Journal of the American College of Cardiology (free)
Related guidelines: Preventing and Experiencing Ischemic Heart Disease as a Woman: State of the Science: A Scientific Statement From the American Heart Association (free) AND Acute Myocardial Infarction in Women: A Scientific Statement From the American Heart Association (free) AND AHA/ACOG: Reduction of Cardiovascular Disease in Women Through Collaboration with Obstetricians and Gynecologists (free)
5 – Review: What’s New in the Management of Malaria? – Infectious Disease Clinics of North America (free)
6 – Evaluation and accurate diagnoses of pediatric diseases using artificial intelligence – Nature Medicine (link to abstract – $ for full-text)
Commentaries: A.I. Shows Promise as a Physician Assistant – The New York Times (10 articles per month are free) AND Expert reaction to use of AI in evaluation and diagnosis of childhood diseases – Science Media Centre (free)
7 – Association of Antibiotic Treatment With Outcomes in Patients Hospitalized for an Asthma Exacerbation Treated With Systemic Corticosteroids – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Should Hospitalized Asthma Patients Receive Antibiotics? – MedicalResearch.com (free) AND No benefit of antibiotic treatment for hospitalised asthma patients – medwire News (free) AND Antibiotic therapy for asthma exacerbation associated with longer hospital stay – 2 Minute Medicine (free) AND Antibiotics Provide No Added Benefit in Severe Asthma Flares – ACEPNow (free)
8 – Association of the Youth-Nominated Support Team Intervention for Suicidal Adolescents With 11- to 14-Year Mortality Outcomes: Secondary Analysis of a Randomized Clinical Trial – JAMA Psychiatry (link to abstract – $ for full-text)
Commentaries: Fewer Deaths Seen Among Young Adults Who Got Extra Adult Support as Suicidal Teens – Michigan Medicine (free) AND Intervention for Suicidal Adolescents May Reduce Long-Term Mortality – Psychiatric News Alert (free)
Commentaries: Improved Diet Can Ease Depression Symptoms, Enhance Mood – PsychCentral (free) AND Many Different Diets Can Improve Mood And Reduce Depression Symptoms, Study Finds – Forbes (free) AND A diet rich in fiber and vegetables can relieve depression – Medical News Today (free)
Commentary: Hearts and minds: fruit and veg boost well-being – University of Leeds (free) AND Eating more fruit and veg ‘improves mental wellbeing’ – NHS Choices (free)
Mon, February 11 – 10 Stories of The Day!
11 Feb, 2019 | 00:32h | UTC
1 – Cough (acute): antimicrobial prescribing – National Institute for Health and Care Excellence (free)
Infographic: 2-page visual summary of the recommendations (free PDF)
See also: NICE Antimicrobial prescribing guidelines (resource covering many common conditions) AND NICE Summary of antimicrobial prescribing guidance – managing common infections (free PDF)
Commentaries: NIH study provides answer to long-held debate on blood sugar control after stroke – National Institute of Health (free) AND Stroke: Intensive Blood Sugar Control Did Not Improve Outcomes – MedicalResearch.com (free) AND Live from the ISC: Standard treatment of hyperglycaemia in acute ischaemic stroke outperforms an intensive approach – NeuroNews (free)
Related Cochrane Review: Insulin for glycaemic control in acute ischaemic stroke (free) AND Summary: Controlling high blood sugar levels with insulin in people who have had an acute ischaemic stroke (free)
“Intensive glucose control (80–130mg/dL) does not improve 90-day functional outcome and increases the risk of severe hypoglycaemia.” (from NeuroNews)
Commentary: FDA Emphasizes Lymphoma Risk in Women with Breast Implants – NEJM Journal Watch (free)
Related: Study: Long-term Outcomes of Silicone Breast Implants (link to abstract and commentary) AND Research: Breast Implants and the Risk of Anaplastic Large-Cell Lymphoma in the Breast (link to abstract and commentary) AND Breast Implant-Associated Anaplastic Large Cell Lymphoma (link to previous FDA report and commentaries)
4 – Five warning signs of overdiagnosis – The Conversation (free)
Related: Overdiagnosis: Causes and Consequences in Primary Health Care (free) AND Screening: How Overdiagnosis and Other Harms can Undermine the Benefits (free) AND WONCA Position Paper on Overdiagnosis and Action to be Taken (free) AND Overdiagnosis: what it is and what it isn’t (free) AND Review: Overdiagnosis Across Medical Disciplines (free) AND Too much medical care: bad for you, bad for health care systems (free)
5 – Viewpoint: Potential Excessive Testing at Scale: Biomarkers, Genomics, and Machine Learning – JAMA (free for a limited period)
6 – Managing Antidepressant Discontinuation: A Systematic Review – Annals of Family Medicine (free)
Commentary: Psychotherapy Ups Odds of Tapering Off Antidepressants – Medscape (free registration required)
Commentary: How often should patients with T2D be screened for retinopathy? – Univadis (free registration required)
Related: Evidence‐based Guidelines for Screening of Diabetic Retinopathy (free)
“This review supports lengthening of the screening interval of patients with Type 2 diabetes without retinopathy at last screening session”
9 – Quality and Experience of Outpatient Care in the United States for Adults with or Without Primary Care – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Patients Engaged in Primary Care More Likely to Receive High-Value Care, Report Better Healthcare Experience – AJMC (free) AND Study: Patients with primary care physicians get better healthcare – UPI (free) AND Patients with primary care have better quality health and experience – Brigham and Women’s Hospital (free) AND Primary care utilization associated with increased high-value care – 2 Minute Medicine (free)
10 – Two-Year Survival Comparing Web-Based Symptom Monitoring vs Routine Surveillance Following Treatment for Lung Cancer – JAMA (link to abstract – $ for full-text)
Commentary: Lung cancer OS benefit with patient-reported symptom monitoring – Medwire News (free)
See Original Article: #ASCO2017 – Survival in a Trial Assessing Patient-Reported Outcomes for Symptom Monitoring During Cancer Treatment (free study and commentaries)
Fri, February 8 – 10 Stories of The Day!
8 Feb, 2019 | 00:44h | UTC
1 – Fluid administration for acute circulatory dysfunction using basic monitoring: narrative review and expert panel recommendations from an ESICM task force – Intensive Care Medicine (free for a limited period)
Note: if the above link is paywalled, try this one
2 – Recommended Childhood and Adolescent Immunization Schedules: United States, 2019 – Pediatrics (free)
Table 1. Recommended Child and Adolescent Immunization Schedule for ages 18 years or younger, United States, 2019 (free)
Table 2. Catch-up immunization schedule for persons aged 4 months–18 years who start late or who are more than 1 month behind, United States, 2019 (free)
Table 3. Recommended Child and Adolescent Immunization Schedule by Medical Condition, United States, 2019 (free)
See also: CDC Immunization Schedules for Healthcare Providers (free resources) AND Recommended Adult Immunization Schedule, United States, 2019 – Annals of Internal Medicine (free)
4 – Ending the HIV Epidemic: A Plan for America – U.S. Department of Health & Human Services (free)
Summary: What is ‘Ending the HIV Epidemic: A Plan for America’? – HIV.gov (free)
Related JAMA Editorial: Ending the HIV Epidemic: A Plan for the United States (free for a limited period)
Commentary: U.S. Announces Plan to Reduce New HIV Diagnoses by 90% Over Next Decade – NEJM Journal Watch (free)
Commentaries: U.K. Doctors Call for Caution in Children’s Use of Screens and Social Media – The New York Times (10 articles per month are free) AND Experts respond to CMO report on screen-time and social media – Science Media Centre (free) AND Do not let children take electronic devices into bedrooms, say doctors – The Guardian (free) AND Screen time: Children advised not to use electronic devices at dinner – BBC (free)
Related Guidelines: Media devices in pre-school children: the recommendations of the Italian pediatric society – Italian Journal of Pediatrics (free) AND Media and Young Minds – Recommendations from The American Academy of Pediatrics (free)
See also: Children, Adolescents and Screens: What We Know and What We Need To Learn (Pediatrics Supplement with free articles)
6 – Guide to Statistics and Methods: Number Needed to Treat: Conveying the Likelihood of a Therapeutic Effect – JAMA (free for a limited period)
Related: Number needed to treat (NNT) in clinical literature: an appraisal – BMC Medicine (free) AND The Numbers Needed to Treat and Harm (NNT, NNH) Statistics: What They Tell Us and What They Do Not – The Journal of Clinical Psychiatry (free)
See also: The NNT Website (resource on the subject with tutorials and practical examples)
Source: Medscape
8 – Education and cognitive reserve in old age – Neurology (link to abstract – $ for full-text)
Commentaries: Education may not protect against dementia as previously thought – American Academy of Neurology (free) AND Does education really protect against dementia? – Medical News Today (free) AND Education won’t help much when it comes to dementia, study says – CNN (free)
Editorial: Suicide falls by a third globally (free for a limited period)
Commentaries: Global suicide mortality: Using data to inform action and monitor progress – The BMJ Opinion (free) AND Global rates of suicide death have fallen by a third since 1990, study finds – CNN (free)
Commentaries: HPV cervical screening test switch ‘effective’, says pilot study – Cancer Research UK (free) AND Cervical screening intervals could be safely extended to at least five years – Pulse (free)
Related: USPSTF Statement: Screening for Cervical Cancer (free guidance and commentaries) AND Study: Little Benefit in Screening Women Aged 55 with a Negative HPV DNA test (link to abstract and commentaries) AND Randomized Trial: Cervical Cancer Screening with Cervical HPV Testing vs Cytology Testing (link to abstract and commentaries)
“The lower incidence of cervical intraepithelial neoplasia grade 3 or worse and cervical cancer at present screening intervals would strongly support the safety of extending the intervals to at least five years without increasing the risk of potentially life-threatening disease.”
Thu, February 7 – 10 Stories of The Day!
7 Feb, 2019 | 01:20h | UTC
Commentaries: Expert panel strongly recommends against surgery for the most common shoulder pain – MedicalXpress (free) AND Guidelines Recommend Against Surgery for Subacromial Pain Syndrome – NEJM Journal Watch (free)
Related Systematic Reviews: Subacromial decompression surgery for adults with shoulder pain: a systematic review with meta-analysis – British Journal of Sports Medicine (free) AND Subacromial Decompression Surgery for Rotator Cuff Disease – Cochrane Library (link to article and randomized trials on the subject)
2 – Tonsillectomy in Children (Update) – American Academy of Otolaryngology–Head and Neck Surgery (free)
News Release: Tonsillectomy in children: Update to guidelines for treating and managing care (free)
Commentaries: Updated Pediatric Tonsillectomy Guidelines Stress Watchful Waiting – NEJM Journal Watch (free) AND Guideline urges physicians to stop prescribing antibiotics, codeine for tonsillectomies – Healio (free registration required)
Related: British Thoracic Society Guideline for bronchiectasis in adults – Thorax (free)
4 – Alex Nowbar’s research reviews, 5 February 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
5 – Abdominal Wall Pain: A Common Clinical Problem – Mayo Clinic Proceedings (free for a limited period)
6 – Incidence, Predictors, and Outcomes of In-Hospital Percutaneous Coronary Intervention Following Coronary Artery Bypass Grafting – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: Unplanned PCI After CABG – American College of Cardiology (free)
7 – Cancer cliches to avoid: I’m not ‘brave’ – BBC (free)
Related: Why cancer is not a war, fight, or battle (free commentaries)
8 – Effect of aerobic exercise on cognition in younger adults: A randomized clinical trial – Neurology (link to abstract – $ for full-text)
Commentary: Exercise may improve thinking skills in people as young as 20 – American Academy of Neurology (free)
Commentaries: Undisclosed financial relationships revealed between doctors and drug companies – The Guardian (free) AND 24% of clinical guideline authors may have undisclosed ties to drug industry – Cardiovascular Business (free) AND Influential doctors aren’t disclosing their drug company ties – Croakey (free)
Related: Study: Financial Conflicts of Interest Among Authors of Clinical Guidelines (link to abstract and commentaries) AND Authors of premier medical textbook didn’t disclose $11 million in industry payments (free commentary) AND Study: Financial Conflicts of Interest Among Authors of Urology Guidelines (link to abstract) AND Perspective: Hidden Conflicts? (free) AND Study: Association of Compensation to Physicians From Industry and Self-declared Conflict of Interest (link to abstract and commentaries) AND Study: Financial Conflicts of Interest Among Oncologist Authors of Reports of Clinical Drug Trials (link to abstract and commentaries) AND “What These Medical Journals Don’t Reveal: Top Doctors’ Ties to Industry” (free commentary) AND Study: Assessment of Pharmaceutical Company and Device Manufacturer Payments to Gastroenterologists and Their Participation in Clinical Practice Guideline Panels (free)
Wed, February 6 – 10 Stories of The Day!
6 Feb, 2019 | 01:20h | UTC
Related Guidelines: Evidence-based guideline update: Pharmacologic treatment for episodic migraine prevention in adults: Report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society (free) AND Pharmacological management of migraine – Scottish Intercollegiate Guidelines Network (free)
Related: The interstitial lung disease multidisciplinary meeting: A position statement from the Thoracic Society of Australia and New Zealand and the Lung Foundation Australia (free) AND Interstitial Lung Disease and Pulmonary Fibrosis: A Practical Approach for General Medicine Physicians with Focus on the Medical History – Journal of Clinical Medicine (free) AND Pharmacological management of progressive-fibrosing interstitial lung diseases: a review of the current evidence – European Respiratory Review(free)
Related Guidelines: Consensus statement on concussion in sport—the 5th international conference on concussion in sport held in Berlin, October 2016 – British Journal of Sports Medicine (free) AND Implementation of the 2017 Berlin Concussion in Sport Group Consensus Statement in contact and collision sports: a joint position statement from 11 national and international sports organisations – British Journal of Sports Medicine (free) AND Clinical Report: Sport-Related Concussion in Children and Adolescents – Pediatrics (free)
4 – Early Subthreshold Aerobic Exercise for Sport-Related Concussion: A Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)
Commentaries: For Teens with Concussion, Moderate Aerobic Activity Can Shorten the Time to Recovery – NEJM Journal Watch (free) AND Concussion treatment: Adolescent athletes ‘prescribed’ aerobic exercise recovered faster – University at Buffalo (free)
5 – Comparing Automated Office Blood Pressure Readings With Other Methods of Blood Pressure Measurement for Identifying Patients With Possible Hypertension: A Systematic Review and Meta-analysis – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Automated BP Readings More Accurate Than Manual Measurements – NEJM Journal Watch (free) AND Automated office BP readings best routine measures – MDedge Cardiology (free)
6 – Podcast: #137 Hyperkalemia Master Class with Joel Topf MD – The Curbsiders Internal Medicine Podcast (free)
Commentary: AI algorithm IDs wrist fractures with 98% sensitivity – AI in Healthcare (free)
8 – Reviewing inhaler technique for older people with COPD can improve disease control – NIHR Signal (free)
Original Study: Inhaler Technique Education and Exacerbation Risk in Older Adults with Asthma or Chronic Obstructive Pulmonary Disease: A Meta‐Analysis – Journal of the American Geriatrics Society (free)
9 – Report: Health systems respond to noncommunicable diseases: time for ambition (2018) – World Health Organization Europe (free PDF)
Commentaries: How feasible is the global elimination of HCV infection? – The Lancet (free) AND HCV Elimination Is Possible, First Estimates Suggest – Medscape (free registration required) AND Major progress against hep C by 2030 is possible, but will need vast improvements in screening, prevention, treatment – MedicalXpress (free) AND Big Gains Against Hep C Possible With Big Investment – U.S. News (free)
Tue, February 5 – 10 Stories of The Day!
5 Feb, 2019 | 00:47h | UTC
1 – Recommended Adult Immunization Schedule, United States, 2019 – Annals of Internal Medicine (free)
3 – Guideline: Medical management of abortion – World Health Organization (free)
4 – Systematic Review: Exercise for preventing falls in older people living in the community – Cochrane Library (free)
News Release: New Cochrane review assesses the benefits and harms of exercise for preventing falls in older people living in the community (free)
Commentaries: Experts assess benefits and harms of exercise for preventing falls in older people – University of Manchester (free) AND Exercise prevents falls in older people – but will any type of exercise do? – Evidently Cochrane (free)
Related: Recommendation Statement: Falls Prevention in Community-Dwelling Older Adults (several guidelines on the subject) AND Meta-analysis: Association of Long-term Exercise Training With Risk of Falls, Fractures, Hospitalizations, and Mortality in Older Adults (link to abstract and commentary) AND Systematic Review: Interventions for Preventing Falls in Older People (free study and commentary) AND Meta-analysis: reducing falls in older adults recently discharged from hospital (link to abstract and commentary)
5 – Guideline Synopsis: Management of Blood Cholesterol – JAMA (free)
Editorial: A New Personalized, Patient-Centric, and Cost-Conscious Guideline for Contemporary Cholesterol Management (free)
Original Guideline: New AHA/ACC Guideline on the Management of Blood Cholesterol (free guideline and resources)
6 – International Consensus Guidelines for the Optimal Use of the Polymyxins – Pharmacotherapy (free)
Endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for Anti‐infective Pharmacology (ISAP), Society of Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP).
7 – Review: Coronary Embolus: An Underappreciated Cause of Acute Coronary Syndromes – JACC: Cardiovascular Interventions (free for a limited period)
8 – Editorial: Why You Should Be Careful About 23andMe’s Health Test – The New York Times (free)
9 – EBM Verdict: Lorcaserin in obesity: minimal benefits and ill-defined harms – BMJ Evidence Based Medicine (free)
10 – Special Issue: Artificial Intelligence in Health Care – AMA Journal of Ethics (free articles) (via @EricTopol see Tweet)
Mon, February 4 – 10 Stories of The Day!
4 Feb, 2019 | 00:01h | UTC
News Release: For older people, medications are common; AGS Beers Criteria aims to make them appropriate, too (free)
Commentary: AGS: Beers Criteria for Potentially Inappropriate Med Use in Older Adults Updated – MPR (free)
2 – Guideline: Polypharmacy: Getting our medicines right – Royal Pharmaceutical Society (free)
Shorter Version: Polypharmacy (free)
Commentary: Pharmacists call for regular reviews of medicines – BBC (free)
Related: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
3 – Editorial: Humanizing the intensive care unit – Critical Care (free)
News Release: ATS Publishes New Clinical Guideline on Home Oxygen for Children (free)
Commentaries: Never too old for statin treatment? – The Lancet (free) AND Efficacy and safety of statin therapy in older people – expert comment – London School of Hygiene & Tropical Medicine (free) AND Expert reaction to meta-analysis looking at statins and cardiovascular events in all ages – Science Media Centre (free) AND Statin therapy reduces cardiovascular disease risk in older people – University of Oxford (free)
Related Guidelines: Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures: An Updated Report by the American Society of Anesthesiologists Task Force on Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration (free) AND Perioperative fasting in adults and children: guidelines from the European Society of Anaesthesiology (free)
Related Systematic Review: Practice Guideline Recommendations on Perioperative Fasting – Journal of Parenteral and Enteral Nutrition (free)
Related Narrative Review: Nothing by Mouth at Midnight: Saving or Starving? A Literature Review – Gastroenterology Nursing (free)
“‘It is safe and recommended for all children able to take clear fluids, to be allowed and encouraged to have them up to 1 h before elective general anaesthesia’.”
Related Guideline: Depression in adults: recognition and management – National Institute for Health and Care Excellence (free)
8 – When Is the Surgeon Too Old to Operate? – The New York Times (10 articles per month are free)
Related: Perspective: Assessing the Performance of Aging Surgeons (free for a limited period) AND Observational Study: Age and Sex of Surgeons and Mortality of Older Surgical Patients (free study and commentary) AND The Elderly and Driving: When Is It Time to Hit the Brakes? – The New York Times (10 articles per month are free)
Commentary: Teens who use e-cigarettes are FOUR TIMES more likely to take up tobacco smoking than teens who don’t, study says – The Daily Mail (free)
Related: Report: Public Health Consequences of E-Cigarettes (free report and commentaries) AND Simulation model: quantifying the health benefits and harms of e-cigarettes (free study and commentary) AND E-cigarettes: A win or loss for public health? – Knowable Magazine (free) AND FDA Takes New Steps to Address Epidemic of Youth E-Cigarette Use (free statement and commentaries)
10 – Benefits of non‐invasive ventilation in acute hypercapnic respiratory failure – Respirology (free)
Related Guidelines: BTS/ICS guideline for the ventilatory management of acute hypercapnic respiratory failure in adults – Thorax (free) AND The Japanese Respiratory Society Noninvasive Positive Pressure Ventilation (NPPV) Guidelines (free) AND Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline – European Respiratory Journal (free)
Related Reviews: Non‐invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease – Cochrane Library (free) AND Noninvasive ventilation in acute respiratory failure: which recipe for success? – European Respiratory Review (free)
Fri, February 1 – 10 Stories of The Day!
1 Feb, 2019 | 04:28h | UTC
1 – AACE/ACE Comprehensive Type 2 Diabetes Management Algorithm 2019 – Endocrine Practice (Free PDF and Slide Presentations)
Related Guidelines: ADA 2019 Standards of Medical Care in Diabetes (free supplement) AND Diabetes Canada 2018 clinical practice guidelines for the prevention and management of diabetes in Canada (free)
2 – Solutions for non-communicable disease prevention and control – The BMJ (free articles)
3 – PSA’s Medicine Safety: Take Care – Pharmaceutical Society of Australia (free PDF)
News Release: Problems with medicines behind 250,000 hospital admissions annually (free)
“The report reveals that 250,000 Australians are hospitalised each year, with another 400,000 presenting to emergency departments, as a result of medication errors, inappropriate use, misadventure and interactions. At least half of this could have been prevented.”
4 – Fatal flaws in clinical decision making – ANZ Journal of Surgery (free)
Commentary: Fatal flaws in clinical decision making – PSNet (free)
5 – Intermittent iron supplementation for reducing anaemia and its associated impairments in adolescent and adult menstruating women – Cochrane Library (free)
Summary: Iron supplements taken one, two or three times a week for preventing anaemia, and its consequences in menstruating women – Cochrane Library (free)
“In comparison with daily supplementation, the provision of iron supplements intermittently is probably as effective in preventing or controlling anemia”
6 – General health checks in adults for reducing morbidity and mortality from disease – Cochrane Library (free)
Summary: General health checks for reducing illness and mortality – Cochrane Library (free)
“General health checks are unlikely to be beneficial.”
9 – A.I. Could Worsen Health Disparities – The New York Times (free)
“In a health system riddled with inequity, we risk making dangerous biases automated and invisible.”
“The USPSTF recommends prophylactic ocular topical medication for all newborns to prevent gonococcal ophthalmia neonatorum. (A recommendation)”
Thu, January 31 – 10 Stories of The Day!
31 Jan, 2019 | 01:24h | UTC
1 – Oral versus Intravenous Antibiotics for Bone and Joint Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Related Trial: Partial Oral vs. Intravenous Antibiotic Treatment of Endocarditis (link to abstract and commentaries)
Commentary: Oral antibiotics may work for some ortho, heart infections – CIDRAP (free)
“Oral antibiotic therapy was noninferior to intravenous antibiotic therapy when used during the first 6 weeks for complex orthopedic infection, as assessed by treatment failure at 1 year.”
2 – A Randomized Trial of E-Cigarettes versus Nicotine-Replacement Therapy – New England Journal of Medicine (link to abstract – $ for full-text)
Editorial: The Dangerous Flavors of E-Cigarettes (free)
Commentaries: E-cigarettes more effective than nicotine replacement therapies, finds major trial – Queen Mary University of London (free) AND UK study shows e-cigarettes help adult smokers quit, but US experts urge caution – CNN (free) AND E-Cigarettes Are Effective at Helping Smokers Quit, a Study Says – The New York times (10 articles per month are free) AND E-cigarettes ‘much better for quitting smoking’ – BBC (free) AND Study Found Vaping Beat Traditional Smoking-Cessation Options – NPR (free)
3 – Are Probiotics Money Down the Toilet? Or Worse? – JAMA (free for a limited period)
Related: Randomized Trials: Probiotics Ineffective Against Gastroenteritis (link to abstract and commentaries) AND Perspective: The Problem with Probiotics (free commentaries) AND Probiotics: Does the Evidence Match the Hype? (link to abstract and commentaries) AND Systematic Review: Harms Reporting in Trials with Probiotics (link to abstract and commentaries)
Commentary: Breakfast—the most important meal of the day? – The BMJ Opinion (free)
5 – 10 myths about furosemide – Intensive Care Medicine (free)
Note: if the above link is paywalled, try this one
6 – State of the Art Review: Peripartum cardiomyopathy – The BMJ (free for a limited period)
Related Reviews: Peripartum Cardiomyopathy – Circulation (free) AND Practical management of peripartum cardiomyopathy – Korean Journal of Internal Medicine (free) AND A contemporary review of peripartum cardiomyopathy – Clinical Medicine (free)
8 – Debates in sepsis – ACP Hospitalist (free)
Related: Point and Counterpoint: Should the Surviving Sepsis Campaign Guidelines Be Retired? (free commentaries) AND The 2018 Surviving Sepsis Campaign’s Treatment Bundle: When Guidelines Outpace the Evidence Supporting Their Use (free commentaries)
9 – Why are so many people still dying from snake bites? – BBC (free)
10 – This Is Your Brain Off Facebook – The New York Times (10 articles per month are free)
Original randomized trial, involving nearly 3000 individuals: The Welfare Effects of Social Media (free PDF)
“Expect the consequences to be fairly immediate: More in-person time with friends and family. Less political knowledge, but also less partisan fever. A small bump in one’s daily moods and life satisfaction. And, for the average Facebook user, an extra hour a day of downtime.”
Wed, January 30 – 10 Stories of The Day!
30 Jan, 2019 | 01:33h | UTC
Commentary: Beta-Blocker Use Linked to Lower Risk for COPD Hospitalization – NEJM Journal Watch (free)
Related review and meta-analysis: Beta-blockers in patients with chronic obstructive disease and coexistent cardiac illnesses – COPD Research and Practice (free) AND Beta-blocker use and COPD mortality: a systematic review and meta-analysis – BMC Pulmonary Medicine (free)
Related observational studies: β-Blockers in COPD: A Cohort Study From the TONADO Research Program – CHEST (free) AND Effect of β blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study – The BMJ (free)
2 – Implementation of a Health Plan Program for Switching From Analogue to Human Insulin and Glycemic Control Among Medicare Beneficiaries With Type 2 Diabetes – JAMA (link to abstract – $ for full-text)
Commentary: Medicare Patients with Type 2 Diabetes Safely Switched From Analog to Human Insulin, JAMA Study Finds – AJMC (free)
Related: Meta-Analysis: Comparative Benefits and Harms of Basal Insulin Analogues for Type 2 Diabetes (link to abstract and commentaries) AND Retrospective Observational Study: Basal Insulin Analogs vs NPH Insulin for Type 2 Diabetes (link to abstract and commentaries)
“Patients with type 2 diabetes (T2D) enrolled in a CareMore Health Medicare Part D plan switched from analog to human insulin without significant loss of glycemic control while saving millions for themselves and for the health plan.” (from AJMC)
“1 in 3 medical students has used cannabis, whereas 8.8% were current users”
4 – Ann Robinson’s research reviews, 29 January 2019 – The BMJ Opinion (free)
Ann Robinson reviews the latest research from the top medical journals.
5 – Point-of-Care Ultrasound in General Practice: A Systematic Review – Annals of Family Medicine (free)
6 – Perspective: Promises, promises, and precision medicine – JCI The Journal of Clinical Investigation (free)
Related: Representing a “revolution”: how the popular press has portrayed personalized medicine – Genetics in Medicine (free)
“Hype vs. reality. Vast disconnect between actual achievements of “precision medicine” and how portrayed in popular culture” (via @CaulfieldTim see Tweet)
“Nearly two decades after the first predictions of dramatic success, we find no impact of the human genome project on the population’s life expectancy or any other public health measure.” (via @MuinJKhoury see Tweet)
Commentary: UK Gonorrhea Guideline Guards Against Antibiotic Resistance – MD Magazine (free)
Related Guideline: WHO Guidelines for the Treatment of Neisseria gonorrhoeae – World Health Organization (free)
Commentaries: No benefit to contraception pill intervals — according to guidance – OnMedica (free) AND Is it OK to take the pill every day without a break? – BBC News (free)
News Release: Lagging drug innovation, variations in quality of care and rising health care costs remain major barriers in fight against cardiovascular disease (free)
Commentaries: AHA issues ‘urgent’ call to action: 5 things to know – Cardiovascular Business (free) AND AHA Warns of Stagnating CVD Gains, Barriers to Access, and Dismal Drug Pipeline – TCTMD (free)
10 – Association Between Screen Time and Children’s Performance on a Developmental Screening Test – JAMA Pediatrics (free for a limited period)
Commentaries: Expert reaction to study on use of screen time and child development – Science Media Centre (free) AND Too much toddler screen time tied to worse social, motor skills by kindergarten – Reuters (free) AND More screen time for toddlers is tied to poorer development a few years later, study says – CNN (free) AND Screen time ‘may harm toddlers’ – BBC (free) AND Screen time predicts delays in child development, says new research – The Conversation (free)
Related Guidelines: Media devices in pre-school children: the recommendations of the Italian pediatric society – Italian Journal of Pediatrics (free) AND Media and Young Minds – Recommendations from The American Academy of Pediatrics (free)
See also: Children, Adolescents and Screens: What We Know and What We Need To Learn (Pediatrics Supplement with free articles)
Tue, January 29 – 10 Stories of The Day!
29 Jan, 2019 | 00:23h | UTC
News Release: Updated treatment guidelines for atrial fibrillation recommend a new class of blood thinners to help prevent stroke – American Heart Association (free)
Commentaries: Focused Update of the AHA/ACC/HRS Atrial Fibrillation Guideline – American College of Cardiology (free) AND Popular blood thinner warfarin no longer recommended for most atrial fibrillation cases – CNN (free)
3 – Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Prevention of Cognitive Impairment With Intensive Systolic Blood Pressure Control (free for a limited period)
Commentary: Does intensive blood pressure control reduce dementia? – NIH News Releases (free)
4 – Human Papillomavirus Vaccine Effectiveness and Herd Protection in Young Women – Pediatrics (free)
Commentaries: Three Important Findings From a Study on HPV “Real World” Effectiveness – Pediatrics (free) AND HPV vaccine effective against infection and for herd immunity – 2 Minute Medicine (free)
Related Perspective on Herd Immunity: The Herd to the Rescue: How an Invisible Shield Can Keep us Healthy (free)
Commentaries: Costs of tuberculosis screening among inpatients with HIV – The Lancet Global Health (free) AND Using urine testing to diagnose TB in patients with HIV can save lives and be cost-effective – London School of Hygiene & Tropical Medicine (free)
6 – Perspective: The robot needs a human heart—why AI in medicine brings moral choices into focus – The BMJ Opinion (free)
“Three in four patients that receive a PICC report a complication after discharge – yet very few are ever documented.” (via @vineet_chopra see Tweet)
8 – The Global Syndemic of Obesity, Undernutrition, and Climate Change: The Lancet Commission report (free registration required)
Commentaries: Take on food industry to beat malnutrition and obesity, says report – The Guardian (free) AND Want to fix obesity and climate change at the same time? Make Big Food companies pay. – VOX (free) AND To fix climate change, fix the obesity and starvation epidemics, reports say – CNN (free)
“Holding people responsible for their obesity detracts attention from the obesogenic systems that produce obesity” (via @TheLancet see Tweet)
Commentary: Aerobic exercise is an effective treatment for depression – NIHR Signal (free)
Related Study: Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study – JAMA Psychiatry (link to abstract – $ for full-text) AND Commentary: Exercise can reduce risk for depression, research shows – UPI (free)
10 – Physical activity, common brain pathologies, and cognition in community-dwelling older adults – Neurology (link to abstract – $ for full-text)
Commentaries: Daily Movement — Even Household Chores — May Boost Brain Health In Elderly – NPR (free) AND Keep Moving to Keep Brain Sharp in Old Age – U.S. News (free) AND Activity sharpens even dementia-affected brains, report suggests – The Guardian (free)
Mon, January 28 – 10 Stories of The Day!
28 Jan, 2019 | 00:01h | UTC
Original Guideline: Diabetes Canada 2018 clinical practice guidelines for the prevention and management of diabetes in Canada (free) AND Quick Reference Guide (free PDF)
See also: ADA 2019 Standards of Medical Care in Diabetes (free supplement) AND Standards of Medical Care in Diabetes—2019 Abridged for Primary Care Providers (free PDF)
Related: Research: Low-Dose Abiraterone With Food vs Standard Dose Abiraterone In Prostate Cancer (link to abstract and commentaries) AND Tackling the High Cost of Cancer Care (free commentaries)
4 – Viewpoint: The Rise of Pseudomedicine for Dementia and Brain Health – JAMA (free for a limited period)
5 – Dear Editor (An Authors’ Wish List to Medical Journal Editors) – Microbiology (free)
6 – Dispatch from Davos: Hospitals of the future will not be traditional hospitals – STAT (free)
7 – Injuries Associated With Standing Electric Scooter Use – JAMA Network Open (free)
Invited Commentary: Shareable 2-Wheeled Vehicles—A New Public Health Problem? (free)
Commentaries: In-Hospital Acute MI: Despite Numerous Predictors, Solutions Remain Elusive – TCTMD (free) AND In-Hospital Acute MI Common, Outcomes Poor – MedPage Today (free registration required)
Commentaries: Spinal Fractures Can Be Terribly Painful. A Common Treatment Isn’t Helping – The New York Times (10 articles per month are free) AND Spinal Fusions Ineffective for Fracture Pain, Says ASBMR – Medscape (free registration required)
Related: Randomized Trial: Vertebroplasty vs. Sham Procedure for Acute Osteoporotic Vertebral Compression Fractures – The BMJ (free study and commentary) AND Cochrane Review: percutaneous vertebroplasty for osteoporotic vertebral compression fracture (free article and summary)
10 – Initiative to Improve Exclusive Breastfeeding by Delaying the Newborn Bath – Journal of Obstetrics, Gynecology and Neonatal Nursing (free for a limited period)
Commentaries: Delaying newborn baths increases rates of breastfeeding – Cleveland Clinic (free) AND Delaying Newborn Baths Boosts Breastfeeding Rates – Medscape (free registration required)
Fri, January 25 – 10 Stories of The Day!
25 Jan, 2019 | 00:01h | UTC
Part 2: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference – Kidney International (free)
Related: See All KDIGO Guidelines (all free)
2 – AAP Policy Statement: Principles of Pediatric Patient Safety: Reducing Harm Due to Medical Care – Pediatrics (free)
News Release: Make pediatric patient safety a priority: AAP policy highlights common errors (free)
3 – Long-Term Effects of Finasteride on Prostate Cancer Mortality – New England Journal of Medicine ($ for full-text)
Commentaries: Final verdict on finasteride: Safe, effective prevention for prostate cancer – eCancer News (free) AND Prostate Drug Finasteride Can Safely Lower Cancer Risk, Study Says – U.S. News (free)
4 – Perspective: Climate Change — A Health Emergency – New England Journal of Medicine (free)
Related: 250,000 deaths a year from climate change is a ‘conservative estimate,’ research says – CNN (free) AND Climate Change Is a Public Health Emergency: Here are eight reasons why – Scientific American (free)
See also: WHO Report: Health and Climate Change (free report and commentaries) AND The 2018 Report of the Lancet Countdown on Health and Climate Change (free report and commentaries) AND Projections of Temperature-Related Excess Mortality Under Climate Change Scenarios (free study and commentaries) AND Quantifying Excess Deaths Related to Heatwaves Under Climate Change Scenarios (free study and commentaries)
5 – Clinically‐indicated replacement versus routine replacement of peripheral venous catheters – Cochrane Library (free)
Summary: Replacing a peripheral venous catheter when clinically indicated versus routine replacement – Cochrane Library (free)
Commentaries: Healing time for ankle fracture could be shorter – OnMedica (free) AND Casting for Ankle Fractures? 3 Weeks May Be Enough – NEJM Journal Watch (free)
7 – Head to Head: Should we rename low risk cancers? – The BMJ (free)
8 – Perspective: The Death of the Sick Day – The New York Times (10 articles per month are free)
“For many office workers, “working from home” has replaced a day spent recovering under the covers.”
Commentaries: Eating Fried Foods Linked To Heart Disease, Earlier Deaths In Women Over 50 – Kaiser Health News (free) AND Fried Foods Tied to Heart Disease in Women – The New York Times (10 articles per month are free)
Commentaries: Physical activity reduces mortality in patients with diabetes: Exercise programs for diabetics are a cost effective treatment and should be reimbursed – European Society of Cardiology (free) AND Exercise Must Be a Prescription for Those With Type 2 Diabetes, European Cardiologists Say – AJMC (free) AND Exercise cuts mortality risk for people with type 2 diabetes, report says – UPI (free)
Thu, January 24 – 10 Stories of The Day!
24 Jan, 2019 | 00:27h | UTC
Related Guidelines: 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension (free) AND Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society (free)
2 – Randomized Delayed-Start Trial of Levodopa in Parkinson’s Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Good News, Bad News on Levodopa for Parkinson’s Disease – U.S. News (free)
3 – Interventions for emergency contraception – Cochrane Library (free)
Summary: Methods of emergency contraception – Cochrane Library (free)
4 – Early discontinuation of antibiotics for febrile neutropenia versus continuation until neutropenia resolution in people with cancer – Cochrane Library (free)
5 – Epidemiology, Pathophysiology, and Management of Hepatorenal Syndrome – Seminars in Nephrology (free for a limited period)
Related Guidelines: 2018 KASL clinical practice guidelines for liver cirrhosis: Ascites and related complications – Clinical and Molecular Hepatology (free) AND 2018 Recommendations of the Brazilian Society of Hepatology for the management of acute kidney injury in patients with cirrhosis – Arquivos de Gastroenterologia (free PDF)
6 – The BMJ Special Collection: Innovating for neglected diseases in South Asia (free articles)
Related: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
8 – 10 Global Health Issues to Watch in 2019 – IntraHealth (free) (via @ghn_news)
Related: WHO: Ten Threats to Global Health in 2019 (free)
Commentary: Study confirms 1-hour discharge rule for patients given naloxone after opiate overdose – Society for Academic Emergency Medicine (free)
10 – Should We Resect and Discard Low Risk Diminutive Colon Polyps – Clinical Endoscopy (free PDF)
Related Guidelines: Evidence-based clinical practice guidelines for management of colorectal polyps – Journal of Gastroenterology (free) AND Colonoscopy surveillance after colorectal cancer resection: recommendations of the US multi-society task force on colorectal cancer – Gastroenterology (free)
Wed, January 23 – 10 Stories of The Day!
23 Jan, 2019 | 01:31h | UTC
1 – Canada’s Dietary Guidelines – Government of Canada (free)
Homepage: Canada’s Food Guide (free resources)
2 – Automated Triaging of Adult Chest Radiographs with Deep Artificial Neural Networks – Radiology (free for a limited period)
Commentary: AI interprets chest x-rays, prioritizes critical findings – Radiology Business (free)
Original Guidelines: 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy (free) AND 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension (free) AND 2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease (free PDF)
Commentaries: AAA Rupture Rate in England Supports Current Thresholds for Surveillance, Intervention—With Some Caveats – TCTMD (free) AND Safety of Abdominal Aortic Aneurysm Surveillance – American College of Cardiology (free)
6 – Alex Nowbar’s weekly research reviews, 22 January 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
7 – Effect of a Low Free Sugar Diet vs Usual Diet on Nonalcoholic Fatty Liver Disease in Adolescent Boys: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Study shows low-sugar diet effective in boys with nonalcoholic fatty liver disease – University of California (free) AND Low free sugar diet reduces hepatic steatosis in nonalcoholic fatty liver disease in adolescent males – 2 Minute Medicine (free) AND To Fight Fatty Liver, Avoid Sugary Foods and Drinks – The New York Times (10 articles per month are free)
8 – Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis – JAMA (link to abstract – $ for full-text)
Commentaries: Expert reaction to study looking at aspirin use in healthy people, and cardiovascular events and bleeding – Science Media Centre (free) AND Aspirin Modest at Best in Primary CV Prevention – MedPage Today (free registration required) AND When to take (or not take) aspirin to prevent heart trouble – CNN (free)
Related: Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events (link to abstract and commentaries) AND Aspirin Did Not Prevent Deaths or Disability in Healthy Older Adults (free study and commentaries)
Related Guidelines: Clinical Practice Guidelines for Irritable Bowel Syndrome in Korea, 2017 (free) AND American College of Gastroenterology Monograph on Management of Irritable Bowel Syndrome (free) AND Evidence-based clinical practice guidelines for irritable bowel syndrome – Journal of Gastroenterology (free) AND Irritable bowel syndrome in adults: diagnosis and management – National Institute for Health and Care Excellence (NICE) (free)
Related Reviews: Sleep Apnea and Cardiovascular Disease: Lessons from Recent Trials and Need for Team Science – Circulation (free) AND Sleep Apnea: Types, Mechanisms, and Clinical Cardiovascular Consequences – Journal of the American College of Cardiology (free)
Tue, January 22 – 10 Stories of The Day!
22 Jan, 2019 | 01:21h | UTC
Commentary: IASP Updates Classification of Chronic Pain – Clinical Advisor (free)
Editorial: Patient organizations and conflict of interest (free)
Commentaries: Jeremy Taylor: Financial interests of patient organisations – The BMJ Opinion (free) AND Financial interests common in patient reps on NICE appraisal – OnMedica (free)
Related Opinion: Why Big Pharma Must Disclose Payments to Patient Groups (free)
3 – Doing things for no reason in the hospital – The BMJ Opinion (free)
“Many of the things we do as doctors continue simply because “that’s the way we’ve always done it,” says Abraar Karan”
4 – Perspective: Opioids don’t work for most people with chronic pain. So why do we still prescribe them? – The Guardian (free)
Related study: Meta-Analysis: Opioids for Chronic Noncancer Pain (link to abstract and commentaries)
See also: Opioid Wisely – Choosing Wisely Canada (free) AND Guideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free)
5 – Podcast: #136 Sickle Cell Disease, Management & Complications – The Curbsiders Internal Medicine Podcast (free)
6 – Editorial: How to Inoculate Against Anti-Vaxxers – The New York Times (10 articles per month are free)
Related: WHO: Ten Threats to Global Health in 2019 (free statement) AND Measles Outbreaks Show Why Anti Vaxxers Made WHO’s 10 Global Health Threats – Forbes (free)
8 – Duration of Electrocardiographic Monitoring of Emergency Department Patients with Syncope – Circulation (link to abstract – $ for full-text)
Commentaries: How long do people need to be monitored after fainting? Study reveals best ways to catch life-threatening conditions – The Ottawa Hospital (free) AND 2 hours in the ER enough to rule out risky arrhythmias in most syncope patients – Cardiovascular Business (free)
9 – Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: New one-dose drug prevents malaria relapse, studies show – CIDRAP (free)
Commentaries: Blood test detects Alzheimer’s damage before symptoms – Washington University in St. Louis (free) AND Early prediction of Alzheimer’s progression: Blood protein – DZNE – German Center for Neurodegenerative Diseases (free) AND Blood test could detect Alzheimer’s more than 10 years earlier – study – The Guardian (free)
Related: Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons (link to abstract and commentaries) AND Identifying incipient dementia individuals using machine learning and amyloid imaging (free study and commentaries) AND High performance plasma amyloid-β biomarkers for Alzheimer’s disease (link to abstract and commentaries) AND Amyloid PET Scan for Predicting Alzheimer’s Disease in Mild Cognitive Impairment (free study and commentaries) AND Retinal Nerve Fiber Layer Thinning and Future Cognitive Decline (link to abstract and commentaries) AND Artificial Intelligence may Predict Alzheimer’s Years Before Diagnosis (link to abstract and commentaries)
Mon, January 21 – 10 Stories of The Day!
21 Jan, 2019 | 01:05h | UTC
1 – Guideline: Management of Acute Compartment Syndrome – American Academy of Orthopaedic Surgeons (free PDF)
News Release: American Academy of Orthopaedic Surgeons approves clinical practice guideline for management of acute compartment syndrome (free)
2 – Adrenaline and vasopressin for cardiac arrest – Cochrane Library (free)
Summary: Adrenaline and vasopressin for cardiac arrest – Cochrane Library (free)
Related: Randomized Trial: Epinephrine in Out-of-Hospital Cardiac Arrest (link to abstract and commentaries) AND Opinion: Epinephrine Harms/Helps in Out of Hospital Cardiac Arrest (free commentaries) AND Review: The Role of Adrenaline in Cardiopulmonary Resuscitation (free)
3 – Subacromial decompression surgery for rotator cuff disease – Cochrane Library (free)
Summary: Surgery for rotator cuff disease (free)
Related Studies: Subacromial Decompression vs Diagnostic Arthroscopy for Shoulder Impingement (free study and commentaries) AND Arthroscopic subacromial decompression for subacromial shoulder pain (free study and commentaries)
“The data in this review do not support the use of subacromial decompression in the treatment of rotator cuff disease manifest as painful shoulder impingement.”
Editorial: A Perspective Regarding the Current State of the Opioid Epidemic (free)
Author Interview: Marketing of Opioid Products and Mortality From Opioid-Related Overdoses; Comparison of Wait Times for New Patients Between the Private Sector and VA Medical Centers (free)
Commentaries: Study Links More Marketing Of Opioids To More Overdose Deaths – CommonHealth (free) AND Heavy marketing of opioid drugs linked to overdose deaths – UPI (free) AND Study Links Drug Maker Gifts for Doctors to More Overdose Deaths – The New York Times (10 articles per month are free)
Related Review: Pregnancy After Bariatric Surgery: Impact on Pregnancy Management and Outcome (free)
Commentary: Home-based hypertension program produces ‘striking’ results – Brigham and Women’s Hospital (free) AND At-home program helped 91% of patients control their BP in 7 weeks – Cardiovascular Business (free)
7 – Associations of Income Volatility With Incident Cardiovascular Disease and All-Cause Mortality in a US Cohort: 1990 to 2015 – Circulation (free for a limited period)
Commentary: Sudden income drops in early adulthood linked with risk of heart disease later – Reuters (free) AND Study links income to heart disease in younger adults – UPI (free)
8 – Worldwide Incidence of Aneurysmal Subarachnoid Hemorrhage According to Region, Time Period, Blood Pressure, and Smoking Prevalence in the Population: A Systematic Review and Meta-analysis – JAMA Neurology (free for a limited period)
9 – Performing an Inadvertent Procedure – JAMA (free for a limited period)
10 – BJS Special Issue on Global Surgery (supplement with free articles)
Selected articles from the supplement:
– Global surgery in an ecosystem for worldwide health
– Ethical considerations in global surgery
– Implementation science and innovation in global surgery
– A realized vision of access to safe, affordable surgical and anaesthesia care
– Training and accrediting international surgeons
– Disseminating technology in global surgery
– Global surgery and the sustainable development goals
– Systematic review of the use of big data to improve surgery in low‐ and middle‐income countries
– Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
Fri, January 18 – 10 Stories of The Day!
18 Jan, 2019 | 01:08h | UTC
1 – Food in the Anthropocene: the EAT–Lancet Commission on healthy diets from sustainable food systems – The Lancet (free articles – registration required)
Summary: EAT-Lancet Commission Brief for Everyone (free)
Commentaries: New Diet Guidelines to Benefit People and the Planet: More Greens for All, Less Meat for Some – The New York Times (10 articles per month are free) AND New ‘planetary health diet’ can save lives and the planet, major review suggests – CNN (free) AND A bit of meat, a lot of veg – the flexitarian diet to feed 10bn – BBC (free)
Commentaries: Haemochromatosis: disorder that causes body to absorb too much iron from food may be major cause of disease – The Conversation (free) AND Haemochromatosis is linked to more disease than previously thought – The BMJ Opinion (free) AND Health impact of genetic ‘iron-overdose disease’ may have been underestimated – NHS News (free)
Related: Will the world embrace Plan S, the radical proposal to mandate open access to science papers? – Science (free) AND The world debates open-access mandates (free) AND China Backs Bold Plan to Tear Down Journal Paywalls (free) AND Europe’s Bold Open-Access Plan Detailed (free) Groundbreaking deal makes large number of German studies free to public – Science (free)
Commentaries: Nearly a fourth of outpatient antibiotics unneeded, study finds – CIDRAP (free) AND Nearly a quarter of antibiotic prescriptions for children and adults may be unnecessary – University of Michigan (free)
5 – Guideline: Prepregnancy counseling – Fertility and Sterility (free)
6 – How to get started in quality improvement – The BMJ (free)
7 – Ebola Has Gotten So Bad, It’s Normal – Foreign Policy (free)
Related: WHO expert: Ebola outbreak to continue at least 6 more months – CIDRAP (free)
8 – Summary: Hypertriglyceridemia Management According to the 2018 AHA/ACC Guideline – American College of Cardiology (free)
9 – Efficacy and safety of aspirin for primary prevention of cardiovascular events: a meta-analysis and trial sequential analysis of randomized controlled trials – European Heart Journal (link to abstract – $ for full-text)
Commentary: Daily Aspirin Use May Do More Harm Than Good for Healthy People – Diagnostic and Interventional Cardiology (free)
Related Study: Aspirin Did Not Prevent Deaths or Disability in Healthy Older Adults (free study and commentaries)
10 – Medscape National Physician Burnout, Depression & Suicide Report 2019 (free registration required)
Commentaries: Burnout Rises Above 50% in Some Specialties, New Survey Shows – Medscape (free registration required) AND No quick fix for physician burnout, depression – Reuters (free) AND More than half of physicians are burned out or depressed – HealthExec (free)
Related Perspectives: Why Physician Burnout Is Endemic, and How Health Care Must Respond – NEJM Catalyst (free) AND Counting the costs: U.S. hospitals feeling the pain of physician burnout – Reuters (free) AND Panic, chronic anxiety and burnout: doctors at breaking point – The Guardian (free) AND The Burnout Crisis in American Medicine – The Atlantic (free) AND Implementing Optimal Team-Based Care to Reduce Clinician Burnout – National Academy of Medicine (free) AND Physician burnout costs up to $17B a year, task force says – HealthcareDive (free)
Related Research: Physician Burnout Can Lead to Major Medical Errors (link to abstract and commentaries) AND Association Between Physician Burnout and Patient Safety, Professionalism, and Patient Satisfaction (link to abstract and commentaries) AND Systematic Review: Prevalence of Burnout Among Physicians (link to abstract and commentaries)
Thu, January 17 – 10 Stories of The Day!
17 Jan, 2019 | 00:01h | UTC
Summary: Angina After PCI – American College of Cardiology (free)
2 – KSHF Guidelines for the Management of Acute Heart Failure (free articles)
Part I. Definition, Epidemiology and Diagnosis of Acute Heart Failure
Part II. Treatment of Acute Heart Failure
Part III. Specific Management of Acute Heart Failure According to the Etiology and Co-morbidity
Related: The use of diuretics in heart failure with congestion — a position statement from the Heart Failure Association of the European Society of Cardiology – European Journal of Heart Failure (free) AND Managing the Patient with Heart Failure in the Emergency Department – European Heart Journal (free)
Original Article: Fourth Universal Definition of Myocardial Infarction (free)
4 – Opinion: Time to abandon early detection cancer screening – European Journal of Clinical Investigation (free)
5 – How telehealth can get healthcare to more people – World Economic Forum (free)
6 – Protein mania: the rich world’s new diet obsession – The Guardian (free)
7 – Implementing School-Based Policies to Prevent Obesity: Cluster Randomized Trial – American Journal of Preventive Medicine (free for a limited period)
Commentaries: School nutrition policies reduce weight gain – National Institutes of Health (free) AND School-based nutritional programs reduce student obesity – Yale University (free)
8 – Artificial intelligence in the intensive care unit – Critical Care (free)
Commentary: First international consensus on fibromuscular dysplasia – Sage (free)
Commentary: Choosing Wisely: Don’t Use Ultrasound to Evaluate Palpable Inguinal Hernia – NEJM Journal Watch (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Wed, January 16 – 10 Stories of The Day!
16 Jan, 2019 | 01:01h | UTC
1 – Ten threats to global health in 2019 – World Health Organization (free)
See other recently published CHEST guidelines on the management of cough in specific populations: Classification of Cough as a Symptom in Adults and Management Algorithms (free) AND Clinically Diagnosing Pertussis-associated Cough in Adults and Children (free) AND Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold (free) AND Cough Due to TB and Other Chronic Infections (free) AND Chronic Cough Due to Gastroesophageal Reflux in Adults (free) AND Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer (free) AND Cough in the athlete (free) AND Occupational and Environmental Contributions to Chronic Cough in Adults (free) AND Treatment of Unexplained Chronic Cough (free) AND Use of Management Pathways or Algorithms in Children With Chronic Cough (free) AND Management of Children With Chronic Wet Cough and Protracted Bacterial Bronchitis (free)
3 – Excess Burden of Mental Illness and Hospitalization in Young-Onset Type 2 Diabetes: A Population-Based Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Mental Illness Risk Increased in Young Onset Diabetes – MedicalResearch.com (free) AND Young-onset type 2 diabetes associated with increased risk of hospitalization frequently due to mental illness – 2 Minute Medicine (free) AND Young Onset Diabetes Linked to High Rates of Mental Illness, Hospitalization – AJMC (free)
4 – Effect of Fecal Microbiota Transplantation on 8-Week Remission in Patients With Ulcerative Colitis: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Video Summary: Can a short duration of anaerobically prepared pooled FMT induce remission in ulcerative colitis? (free)
Commentary: Poo transplant effective treatment for chronic bowel condition – University of Adelaide (free)
See also: Visual Abstract (free)
Commentaries: Heart failure patients need sooner follow-up care – Reuters (free) AND Patients with heart failure have lower risk of death if seen by physician in first 7 days after ED discharge – MedicalXpress (free)
6 – Zackary Berger’s weekly research reviews, 14 January 2019 – The BMJ (free)
“Zackary Berger reviews the latest research from the top medical journals”.
7 – Effect of Nonmyeloablative Hematopoietic Stem Cell Transplantation vs Continued Disease-Modifying Therapy on Disease Progression in Patients With Relapsing-Remitting Multiple Sclerosis: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
See also: Visual Abstract (free)
Commentaries: For some multiple sclerosis patients, knocking out the immune system might work better than drugs – Science (free) AND A remarkable new study shows stem cells can reverse MS in some patients – Vox (free) AND Expert reaction to study looking at blood stem cell transplantation as a MS treatment – Science Media Centre (free)
8 – Opinion: The scandal of surrogates and the missing survival data in cancer trials – BMJ EBM Spotlight (free)
Related Study: Association Between Surrogate End-points and Overall Survival in Oncology (free)
Commentary: USPSTF Reaffirms Drugs for Women at High Risk for Breast Cancer – Medscape (free registration required)
10 – Cardiologist-level arrhythmia detection and classification in ambulatory electrocardiograms using a deep neural network – Nature Medicine (link to abstract – $ for full-text)
Commentaries: Using Artificial Intelligence to Catch Irregular Heartbeats – NIH Director’s Blog (free) AND Machine Matches Docs for Arrhythmia Detection – MedPage Today (free registration required)
Tue, January 15 – 10 Stories of The Day!
15 Jan, 2019 | 00:40h | UTC
1 – American College of Physicians Ethics Manual: Seventh Edition – Annals of Internal Medicine (free)
News Release: American College of Physicians releases new edition of Ethics Manual (free)
“Genetic testing, telemedicine, end-of-life care, and human subjects research are among issues examined in new edition of ACP Ethics Manual” (from News Release)
Commentaries: Beta-Blockers, Calcium Channel Blockers, Mortality in Stable CAD – American College of Cardiology (free) AND CLARIFY: No Survival Benefit With Beta-Blockers Beyond 1 Year Post-MI in Stable CAD – TCTMD (free)
Related Studies: Effect of β‐Blockers Beyond 3 Years After Acute Myocardial Infarction (free) AND B-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction (free study and commentary)
3 – Podcast: #135 Perioperative Medicine: Assess & Optimize Risk – The Curbsiders Internal Medicine Podcast (free audio)
4 – Acute infection & myocardial infarction: How afraid should we be? – PulmCrit (free)
Related Commentary: Acute Infection and Myocardial Infarction – American College of Cardiology (free)
Original Article: Acute Infection and Myocardial Infarction – New England Journal of Medicine (link to abstract – $ for full-text)
5 – Opinion: Why Big Pharma must disclose payments to patient groups – The Conversation (free)
6 – Unethical experiments’ painful contributions to today’s medicine – CNN (free)
7 – The association between adolescent well-being and digital technology use – Nature Human Behavior (link to abstract – $ for full-text)
Commentaries: Technology use explains at most 0.4 percent of adolescent wellbeing, new study finds – University of Oxford (free) AND Expert reaction to adolescent well-being and digital technology use – Science Media Centre (free) AND Screen Time May Be No Worse For Kids Than Eating Potatoes – Forbes (free)
8 – Association of body mass index and waist-to-hip ratio with brain structure: UK Biobank study – Neurology (link to abstract – $ for full-text)
Commentaries: Excessive body fat around the middle linked to smaller brain, study says – CNN (free) AND Excessive body fat around the middle linked to smaller brain size, study finds – American Academy of Neurology (free)
Related Guidelines and Reviews: Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline (free) AND 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines (free) AND Canadian Cardiovascular Society Guidelines for Evaluation and Management of Cardiovascular Complications of Cancer Therapy (free) AND Cardio-Onco-Hematology in Clinical Practice. Position Paper and Recommendations – Revista Espanola de Cardiologia (free) AND Cardiotoxicity of anticancer treatments: Epidemiology, detection, and management – CA: A Cancer Journal for Clinicians (free)