Thu, January 24 – 10 Stories of The Day!

1 – Therapy for Pulmonary Arterial Hypertension in Adults 2018: Update of the CHEST Guideline and Expert Panel Report (free)

Related Guidelines: 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension (free) AND Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society (free)

2 – Randomized Delayed-Start Trial of Levodopa in Parkinson’s Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Good News, Bad News on Levodopa for Parkinson’s Disease – U.S. News (free)

3 – Interventions for emergency contraception – Cochrane Library (free)

Summary: Methods of emergency contraception – Cochrane Library (free)

4 – Early discontinuation of antibiotics for febrile neutropenia versus continuation until neutropenia resolution in people with cancer – Cochrane Library (free)

Summary: Stopping antibiotic therapy early versus continuing until normal neutrophil count in people with cancer with fever and low neutrophil counts – Cochrane Library (free)

5 – Epidemiology, Pathophysiology, and Management of Hepatorenal Syndrome – Seminars in Nephrology (free for a limited period)

Related Guidelines: 2018 KASL clinical practice guidelines for liver cirrhosis: Ascites and related complications – Clinical and Molecular Hepatology (free) AND 2018 Recommendations of the Brazilian Society of Hepatology for the management of acute kidney injury in patients with cirrhosis – Arquivos de Gastroenterologia (free PDF)

6 – The BMJ Special Collection: Innovating for neglected diseases in South Asia (free articles)

7 – Consensus and evidence-based medication review to optimize and potentially reduce psychotropic drug prescription in institutionalized dementia patients – BMC Geriatrics (free)

Related: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)

8 – 10 Global Health Issues to Watch in 2019 – IntraHealth (free) (via @ghn_news)

Related: WHO: Ten Threats to Global Health in 2019 (free)

9 – Hospital Observation Upon Reversal (HOUR) With Naloxone: A Prospective Clinical Prediction Rule Validation Study – Academic Emergency Medicine (free)

Commentary: Study confirms 1-hour discharge rule for patients given naloxone after opiate overdose – Society for Academic Emergency Medicine (free)

10 – Should We Resect and Discard Low Risk Diminutive Colon Polyps – Clinical Endoscopy (free PDF)

Related Guidelines: Evidence-based clinical practice guidelines for management of colorectal polyps – Journal of Gastroenterology (free) AND Colonoscopy surveillance after colorectal cancer resection: recommendations of the US multi-society task force on colorectal cancer – Gastroenterology (free)