Thu, February 14 – 10 Stories of The Day!

1 – Lifetime risk and multimorbidity of non-communicable diseases and disease-free life expectancy in the general population: A population-based cohort study – PLOS Medicine (free)

Commentary: Absence of hypertension, overweight and smoking results in 9 disease-free years and prolonged life expectancy of 6 years – PACE-CME (free)

2 – Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentaries: Ibuprofen may be a ‘reasonable option’ for analgesia after hip replacement – medwire News (free) AND Acetaminophen Plus Ibuprofen Linked to Less Morphine Use After Hip Arthroplasty – NEJM Journal Watch (free) AND Paracetamol plus ibuprofen significantly reduces post-operative morphine use in total hip arthroplasty patients – 2 Minute Medicine (free)

3 – Does This Patient Have a Severe Snake Envenomation? The Rational Clinical Examination Systematic Review – JAMA Surgery (free for a limited period)

Related: Global Mapping of Vulnerability to Snakebite Envenoming (free study and commentaries) AND Why Are So Many People Still Dying from Snake Bites? (free) AND Snakebite finally makes a WHO list of top global health priorities (free) AND Snakebites Make The List Of ‘Neglected Tropical Diseases’ (free)

4 – Risks and benefits of hypotensive resuscitation in patients with traumatic hemorrhagic shock: a meta-analysis – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)

Commentary: Permissive hypotensive resuscitation in patients with traumatic hemorrhagic shock – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)

5 – Zackary Berger’s weekly research reviews, 13 February 2019 – The BMJ Opinion (free)

6 – Medication adherence: Scope of the problem, ways to measure, ways to improve, and the role of the pharmacist – American College of Clinical Pharmacy (free)

7 – Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood: A Systematic Review and Meta-analysis – JAMA Psychiatry (link to abstract – $ for full-text)

Commentaries: Expert reaction to cannabis use in adolescents and risk of depression, anxiety and suicidality – Science Media Centre (free) AND Increased depression and suicidal behavior risk for young cannabis users – McGill University Health Centre (free) AND Cannabis smoking in teenage years linked to adulthood depression – The Guardian (free) AND Teen cannabis use linked to higher risk of adolescent depression – Reuters (free)

8 – Breast cancer deaths averted over 3 decades – Cancer (free)

Commentaries: Treatment Advances Averted More Than Half a Million Breast Cancer Deaths Over 3 Decades – AJMC (free) AND Recent Decrease in Deaths Attributable to Breast Cancer in the United States – The ASCO Post (free)

9 – Association of Left Ventricular Ejection Fraction and Symptoms With Mortality After Elective Noncardiac Surgery Among Patients With Heart Failure – JAMA (link to abstract – $ for full-text)

Commentaries: Symptomatic and non-symptomatic heart failure associated with increased postoperative mortality in non-cardiac elective surgery – 2 Minute Medicine (free) AND LVEF, HF Symptoms, and Mortality After Surgery – American College of Cardiology (free)

10 – Association of dietary macronutrient composition and non-alcoholic fatty liver disease in an ageing population: the Rotterdam Study – Gut (link to abstract – $ for full-text)

Commentary: Eating lots of meat tied to higher risk of liver disease – Reuters (free) AND Diet Heavy in Meat Boosts NAFLD Risk – MedPage Today (free registration required)