Tue, January 22 – 10 Stories of The Day!

1 – Chronic pain as a symptom or a disease: The IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11) – Pain (free)

Commentary: IASP Updates Classification of Chronic Pain – Clinical Advisor (free)

2 – Financial interests of patient organisations contributing to technology assessment at England’s National Institute for Health and Care Excellence: policy review – The BMJ (free)

Editorial: Patient organizations and conflict of interest (free)

Commentaries: Jeremy Taylor: Financial interests of patient organisations – The BMJ Opinion (free) AND Financial interests common in patient reps on NICE appraisal – OnMedica (free)

Related Opinion: Why Big Pharma Must Disclose Payments to Patient Groups (free)

3 – Doing things for no reason in the hospital – The BMJ Opinion (free)

“Many of the things we do as doctors continue simply because “that’s the way we’ve always done it,” says Abraar Karan”

4 – Perspective: Opioids don’t work for most people with chronic pain. So why do we still prescribe them? – The Guardian (free)

Related study: Meta-Analysis: Opioids for Chronic Noncancer Pain (link to abstract and commentaries)

See also: Opioid Wisely – Choosing Wisely Canada (free) AND Guideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free)

5 – Podcast: #136 Sickle Cell Disease, Management & Complications – The Curbsiders Internal Medicine Podcast (free)

6 – Editorial: How to Inoculate Against Anti-Vaxxers – The New York Times (10 articles per month are free)

Related: WHO: Ten Threats to Global Health in 2019 (free statement) AND Measles Outbreaks Show Why Anti Vaxxers Made WHO’s 10 Global Health Threats – Forbes (free)

7 – Weaning failure of cardiovascular origin: how to suspect, detect and treat—a review of the literature – Annals of Intensive Care (free)

8 – Duration of Electrocardiographic Monitoring of Emergency Department Patients with Syncope – Circulation (link to abstract – $ for full-text)

Commentaries: How long do people need to be monitored after fainting? Study reveals best ways to catch life-threatening conditions – The Ottawa Hospital (free) AND 2 hours in the ER enough to rule out risky arrhythmias in most syncope patients – Cardiovascular Business (free)

9 – Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: New one-dose drug prevents malaria relapse, studies show – CIDRAP (free)

10 – Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease – Nature Medicine (free)

Commentaries: Blood test detects Alzheimer’s damage before symptoms – Washington University in St. Louis (free) AND Early prediction of Alzheimer’s progression: Blood protein – DZNE – German Center for Neurodegenerative Diseases (free) AND Blood test could detect Alzheimer’s more than 10 years earlier – study – The Guardian (free)

Related: Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons (link to abstract and commentaries) AND Identifying incipient dementia individuals using machine learning and amyloid imaging (free study and commentaries) AND High performance plasma amyloid-β biomarkers for Alzheimer’s disease (link to abstract and commentaries) AND Amyloid PET Scan for Predicting Alzheimer’s Disease in Mild Cognitive Impairment (free study and commentaries) AND Retinal Nerve Fiber Layer Thinning and Future Cognitive Decline (link to abstract and commentaries) AND Artificial Intelligence may Predict Alzheimer’s Years Before Diagnosis (link to abstract and commentaries)