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Pediatrics – Pulmonology

RCT | Impact of vaping prevention advertisements on adolescents.

14 Oct, 2022 | 13:57h | UTC

Impact of Vaping Prevention Advertisements on US Adolescents: A Randomized Clinical Trial – JAMA Network Open

News Release: Researchers find FDA ‘Real Cost’ ads reduce teen openness to vaping – UNC Lineberger Comprehensive Cancer Center

 

Commentary on Twitter

 

Development of a symptom-based tool for screening of children at high risk of preschool asthma.

11 Oct, 2022 | 13:34h | UTC

Development of a Symptom-Based Tool for Screening of Children at High Risk of Preschool Asthma – JAMA Network Open

News Release: Simple new tool allows primary caregivers to detect young kids at high risk of asthma – McMaster University

 

Commentary on Twitter

 

Systematic Review | Home care for bronchiolitis.

21 Sep, 2022 | 13:14h | UTC

Home Care for Bronchiolitis: a Systematic Review – Pediatrics

Commentary: Home oxygen therapy for bronchiolitis feasible, cost-effective, and favorable to caregivers – Physician’s Weekly

 

Commentary on Twitter

 

Review | COVID-19 in children.

8 Sep, 2022 | 14:43h | UTC

COVID-19 in Children – Pediatric Clinics of North America

 

Systematic Review | Probiotics for preventing acute upper respiratory tract infections.

6 Sep, 2022 | 14:40h | UTC

Probiotics for preventing acute upper respiratory tract infections – Cochrane Library

 

Commentary on Twitter

 

Brief Review | What’s new in pediatric ventilator liberation?

5 Sep, 2022 | 14:29h | UTC

What’s new in paediatric ventilator liberation? – Intensive Care Medicine

 

Commentary on Twitter

 

Study Commentary | Zinc for the prevention or treatment of respiratory tract infections: a new systematic review.

1 Sep, 2022 | 11:46h | UTC

Zinc for the prevention or treatment of respiratory tract infections: A new systematic review – Science-Based Medicine

Original Study: M-A: Zinc might help to stave off respiratory infection symptoms and cut illness duration – “But quality of evidence variable, and no clarity on optimal formulation or dose”.

 

Guideline | Management of preschool wheezing.

31 Aug, 2022 | 11:37h | UTC

Management of Preschool Wheezing: Guideline from the Emilia-Romagna Asthma (ERA) Study Group – Journal of Clinical Medicine

 

Perspective | Should less invasive surfactant administration (LISA) become routine practice in US neonatal units?

29 Aug, 2022 | 11:59h | UTC

Should less invasive surfactant administration (LISA) become routine practice in US neonatal units? – Pediatric Research

Related:

RCT: In preterm infants with respiratory distress syndrome, surfactant administration via a thin catheter did not improve outcomes.

Systematic Review: Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome is associated with reduced risk of death or bronchopulmonary dysplasia, less intubation in the first 72 hours, and reduced incidence of major complications and in‐hospital mortality.

 

RCT | Mepolizumab for urban children with exacerbation-prone eosinophilic asthma.

22 Aug, 2022 | 12:09h | UTC

Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial – The Lancet (link to abstract – $ for full-text)

Commentary: Mepolizumab Cuts Exacerbations in Children With Severe Asthma – HealthDay

 

International clinical practice guidelines for pediatric ventilator liberation.

16 Aug, 2022 | 13:56h | UTC

Executive Summary: International Clinical Practice Guidelines for Pediatric Ventilator Liberation, A PALISI Network Document – American Journal of Respiratory and Critical Care Medicine

 

M-A | The outcome of post-cardiotomy extracorporeal membrane oxygenation in neonates and pediatric patients.

4 Aug, 2022 | 13:48h | UTC

The Outcome of Post-cardiotomy Extracorporeal Membrane Oxygenation in Neonates and Pediatric Patients: A Systematic Review and Meta-Analysis – Frontiers in Pediatrics

 

Brief Review | Lung ultrasound for the diagnosis and management of neonatal respiratory distress syndrome.

4 Aug, 2022 | 13:45h | UTC

Lung Ultrasound for the Diagnosis and Management of Neonatal Respiratory Distress Syndrome: A Minireview – Frontiers in Pediatrics

 

Podcast | Caring for a pediatric patient with ARDS.

4 Aug, 2022 | 13:35h | UTC

#52: The Original “Baby Lung”: PARDS with PedsCrit – The Cribsiders

 

RCT | The effect of inhaled hypertonic saline on lung structure in children aged 3–6 years with cystic fibrosis.

26 Jul, 2022 | 11:50h | UTC

The effect of inhaled hypertonic saline on lung structure in children aged 3–6 years with cystic fibrosis (SHIP-CT): a multicentre, randomised, double-blind, controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

Commentary: Inhaled hypertonic saline improves structural airway changes in children with cystic fibrosis – Healio (free registration required)

 

RCT | Intranasal corticosteroids not beneficial for children with obstructive sleep apnea.

19 Jul, 2022 | 13:27h | UTC

A trial of intranasal corticosteroids to treat the childhood obstructive sleep apnea syndrome – CHEST (link to abstract – $ for full-text)

Commentaries:

Study does not support intranasal corticosteroids for most children with obstructive sleep apnea – Healio

Intranasal corticosteroids not recommended for most children with OSA: study – Medical Dialogues

 

Commentary on Twitter

 

Systematic Review | Anti‐IL‐5 therapies for asthma.

14 Jul, 2022 | 12:40h | UTC

Anti‐IL‐5 therapies for asthma – Cochrane Library

Summary: Mepolizumab, reslizumab or benralizumab for people already taking inhaled steroids and long-acting beta 2-agonists for their asthma – Cochrane Library

 

RCT | Efficacy and safety of Elexacaftor/Tezacaftor/Ivacaftor in children 6 through 11 years of age with cystic fibrosis heterozygous for F508del and a minimal function mutation.

13 Jul, 2022 | 11:07h | UTC

Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 Through 11 Years of Age with Cystic Fibrosis Heterozygous for F508del and a Minimal Function Mutation: A Phase 3B, Randomized, Placebo-Controlled Study – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)

 

Effect of comprehensive smoke-free legislation on neonatal and infant mortality across 106 middle-income countries.

7 Jul, 2022 | 12:26h | UTC

Effect of comprehensive smoke-free legislation on neonatal mortality and infant mortality across 106 middle-income countries: a synthetic control study – The Lancet Public Health

 

FDA orders Juul to remove all its e-cigarettes from US market.

6 Jul, 2022 | 11:46h | UTC

FDA orders Juul to remove all its e-cigarettes from US market – The BMJ

See also:

FDA orders all Juul e-cigarettes off the market – POLITICO

The FDA orders Juul to pull all of its vaping products from the U.S. market – NPR

FDA orders Juul Labs to remove products from US market – CNN

FDA News Release: FDA Denies Authorization to Market JUUL Products – U.S. Food & Drug Administration

RCT | Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis.

6 Jul, 2022 | 11:31h | UTC

Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis: a randomised, controlled clinical trial – Thorax

Commentary: Does Azithromycin antagonize the effect of inhaled tobramycin in cystic fibrosis? – Medical Dialogues

 

Commentary on Twitter

Review | Management of pediatric acute respiratory distress syndrome.

5 Jul, 2022 | 11:42h | UTC

Management of paediatric acute respiratory distress syndrome – BJA Education

M-A | Predictors of sleep disordered breathing in children with Down syndrome.

5 Jul, 2022 | 11:33h | UTC

Predictors of sleep disordered breathing in children with Down syndrome: a systematic review and meta-analysis – European Respiratory Review

Case-Control Study: Accuracy of chest CT in distinguishing cystic pleuropulmonary blastoma from benign congenital lung malformations in children.

1 Jul, 2022 | 11:02h | UTC

Accuracy of Chest Computed Tomography in Distinguishing Cystic Pleuropulmonary Blastoma From Benign Congenital Lung Malformations in Children – JAMA Network Open

Invited Commentary: Can Computed Tomography Scans Reliably Distinguish Pleuropulmonary Blastoma From Congenital Lung Malformations? – JAMA Network Open

 

Commentary on Twitter

 

Cohort Study: Pfizer vaccine effectiveness against omicron in children 5 to 11 years of age.

30 Jun, 2022 | 11:21h | UTC

BNT162b2 Vaccine Effectiveness against Omicron in Children 5 to 11 Years of Age – New England Journal of Medicine

 

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