Perspective | Should less invasive surfactant administration (LISA) become routine practice in US neonatal units? 29 Aug, 2022 | 11:59h | UTC Should less invasive surfactant administration (LISA) become routine practice in US neonatal units? – Pediatric Research Related: RCT: In preterm infants with respiratory distress syndrome, surfactant administration via a thin catheter did not improve outcomes. Systematic Review: Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome is associated with reduced risk of death or bronchopulmonary dysplasia, less intubation in the first 72 hours, and reduced incidence of major complications and in‐hospital mortality.