Open access
Open access
Powered by Google Translator Translator

Pediatrics – Infectious Diseases

A case series of children with acute hepatitis and human Adenovirus infection.

14 Jul, 2022 | 12:56h | UTC

A Case Series of Children with Acute Hepatitis and Human Adenovirus Infection – New England Journal of Medicine (link to abstract – $ for full-text)

Related Study: Clinical Spectrum of Children with Acute Hepatitis of Unknown Cause – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Unexplained Acute Hepatitis in Children: More Evidence for Adenovirus 41 — Two studies point to a suspiciously high prevalence – MedPage Today (free registration required)

 

Commentaries on Twitter

 


M-A | Effectiveness of interventions to improve drinking water, sanitation, and handwashing with soap on risk of diarrheal disease in children in low-income and middle-income settings.

6 Jul, 2022 | 11:56h | UTC

Effectiveness of interventions to improve drinking water, sanitation, and handwashing with soap on risk of diarrhoeal disease in children in low-income and middle-income settings: a systematic review and meta-analysis – The Lancet

 

Commentary on Twitter


RCT | Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis.

6 Jul, 2022 | 11:31h | UTC

Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis: a randomised, controlled clinical trial – Thorax

Commentary: Does Azithromycin antagonize the effect of inhaled tobramycin in cystic fibrosis? – Medical Dialogues

 

Commentary on Twitter


Indeterminate pediatric acute liver failure: clinical characteristics of a temporal cluster of five children in the Netherlands in the spring of 2022.

5 Jul, 2022 | 12:09h | UTC

Indeterminate pediatric acute liver failure: Clinical characteristics of a temporal cluster of five children in the Netherlands in the spring of 2022 – UEG Journal

Related:

Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)

Severe acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization

Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)

Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology

What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 3 – UK Health Security Agency

Case numbers of acute hepatitis of unknown aetiology among children in 24 countries up to 18 April 2022 compared to the previous 5 years – Eurosurveillance

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022 – Eurosurveillance

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens – The Lancet Gastroenterology & Hepatology

Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT

Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC

Hepatitis outbreak in children: What do we know so far? – Imperial College London

Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases

Epidemiological update: Hepatitis of unknown aetiology in children – European Centre for Disease Prevention and Control

Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 2 – UK Health Security Agency

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press


Brief Review | Sudden onset hepatitis in children.

4 Jul, 2022 | 12:41h | UTC

Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)

Related: WHO Updated Report: Severe acute hepatitis of unknown etiology in children. (several articles on the subject)

 

Commentary on Twitter


Cohort Study: Pfizer vaccine effectiveness against omicron in children 5 to 11 years of age.

30 Jun, 2022 | 11:21h | UTC

BNT162b2 Vaccine Effectiveness against Omicron in Children 5 to 11 Years of Age – New England Journal of Medicine

 


WHO Updated Report: Severe acute hepatitis of unknown etiology in children.

28 Jun, 2022 | 11:23h | UTC

Severe acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization

Related:

Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)

Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology

What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 3 – UK Health Security Agency

Case numbers of acute hepatitis of unknown aetiology among children in 24 countries up to 18 April 2022 compared to the previous 5 years – Eurosurveillance

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022 – Eurosurveillance

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens – The Lancet Gastroenterology & Hepatology

Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT

Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC

Hepatitis outbreak in children: What do we know so far? – Imperial College London

Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases

Epidemiological update: Hepatitis of unknown aetiology in children – European Centre for Disease Prevention and Control

Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 2 – UK Health Security Agency

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

 


Long COVID symptoms in SARS-CoV-2-positive children aged 0–14 years and matched controls in Denmark: a national, cross-sectional study.

28 Jun, 2022 | 11:16h | UTC

Long COVID symptoms in SARS-CoV-2-positive children aged 0–14 years and matched controls in Denmark (LongCOVIDKidsDK): a national, cross-sectional study – The Lancet Child & Adolescent Health

News Release: Largest study reports long COVID symptoms in children up to age 14 – Lancet

Commentaries:

Difficult questions about long COVID in children – The Lancet Child & Adolescent Health

Kids do get long COVID, but it seems uncommon, data reveal – CIDRAP

 


EULAR/PRES recommendations for vaccination of pediatric patients with autoimmune inflammatory rheumatic diseases.

24 Jun, 2022 | 11:17h | UTC

EULAR/PRES recommendations for vaccination of paediatric patients with autoimmune inflammatory rheumatic diseases: update 2021 – Annals of Rheumatic Diseases

 


Risk factors for SARS-CoV-2 related severe Multisystem Inflammatory Syndrome in Children investigated in a Swedish population-based study.

23 Jun, 2022 | 10:36h | UTC

News Release: Risk factors for severe COVID-19 complication in children investigated in Swedish population-based study – Karolinska Institutet

Original Study: Risk factors for multisystem inflammatory syndrome in children – A population-based cohort study of over 2 million children – The Lancet Regional Health Europe

 


M-A: Incidence and etiology of infant Gram-negative bacteremia and meningitis in children.

23 Jun, 2022 | 10:27h | UTC

Incidence and aetiology of infant Gram-negative bacteraemia and meningitis: systematic review and meta-analysis – Archives of Disease in Childhood

 


Cohort Study: Risk of myocarditis and pericarditis after the COVID-19 mRNA vaccination in the USA.

22 Jun, 2022 | 12:07h | UTC

Risk of myocarditis and pericarditis after the COVID-19 mRNA vaccination in the USA: a cohort study in claims databases – The Lancet

Commentaries:

COVID-19 mRNA vaccination and myocarditis or pericarditis – The Lancet

Myocarditis and Pericarditis After the COVID-19 mRNA Vaccination – American College of Cardiology

Related:

SARS-CoV-2 Vaccination and Myocarditis in a Nordic Cohort Study of 23 Million Residents – JAMA Cardiology

Myocarditis and pericarditis after COVID-19 vaccination: clinical management guidance for healthcare professionals – UK Health Security Agency

Myocarditis following a third Pfizer vaccination dose in military recruits in Israel.

Myocarditis following COVID-19 BNT162b2 vaccination among adolescents in Hong Kong.

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 


Comparing the Pfizer and Moderna Covid vaccines for young children.

22 Jun, 2022 | 12:02h | UTC

Comparing the Pfizer and Moderna Covid vaccines for young children – STAT

Related: FDA advisers OK COVID-19 vaccines for youngest kids – CIDRAP

 


RCT: Multispecies probiotic for the prevention of antibiotic-associated diarrhea in children.

22 Jun, 2022 | 11:12h | UTC

Multispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)

Commentary: Mixed Results With Probiotic for Kids’ Antibiotic-Related Diarrhea— Randomized trial misses strictly defined endpoint, but researchers point to benefit – MedPage Today (free registration required)

 

Commentary on Twitter

 


M-A: Contemporary trends in global mortality of sepsis among young infants less than 90 days.

22 Jun, 2022 | 11:03h | UTC

Contemporary Trends in Global Mortality of Sepsis Among Young Infants Less Than 90 Days: A Systematic Review and Meta-Analysis – Frontiers in Pediatrics

 


FDA advisers OK COVID-19 vaccines for youngest kids.

17 Jun, 2022 | 11:43h | UTC

FDA advisers OK COVID-19 vaccines for youngest kids – CIDRAP

See also: FDA advisers endorse 1st COVID-19 shots for kids under 5 – Associated Press

 


NICE Guideline: Reducing sexually transmitted infections.

16 Jun, 2022 | 11:15h | UTC

Reducing sexually transmitted infections – National Institute for Health and Care Excellence

 


Perspective | Viruses that were on hiatus during Covid are back — and behaving in unexpected ways.

16 Jun, 2022 | 11:06h | UTC

Viruses that were on hiatus during Covid are back — and behaving in unexpected ways – STAT

 


Phase 2 RCT: Safety and immunogenicity of the AstraZeneca vaccine in children aged 6–17 years.

15 Jun, 2022 | 11:15h | UTC

Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine in children aged 6–17 years: a preliminary report of COV006, a phase 2 single-blind, randomised, controlled trial – The Lancet

Invited Commentary: Increasing children’s global access to COVID-19 vaccines – The Lancet

 


Cohort Study: Prevalence, characteristics, and determinants of suboptimal care in the initial management of community-onset severe bacterial infections in children.

14 Jun, 2022 | 10:52h | UTC

Prevalence, Characteristics, and Determinants of Suboptimal Care in the Initial Management of Community-Onset Severe Bacterial Infections in Children – JAMA Network Open

 


Case Series | Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit.

13 Jun, 2022 | 10:46h | UTC

Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)

Related: Investigating acute hepatitis of unknown origin in children (several resources on the subject)

 

Commentary on Twitter

 


Another study suggests the Omicron variant is associated with a reduced risk of Multisystem Inflammatory Syndrome in Children compared to previous SARS-CoV-2 variants.

10 Jun, 2022 | 12:38h | UTC

Risk and Phenotype of Multisystem Inflammatory Syndrome in Vaccinated and Unvaccinated Danish Children Before and During the Omicron Wave – JAMA Pediatrics

Related study: Severity and Incidence of Multisystem Inflammatory Syndrome in Children During 3 SARS-CoV-2 Pandemic Waves in Israel – JAMA AND Commentary: Kids’ COVID syndrome—MIS-C—less severe in Omicron – CIDRAP

 

Commentary on Twitter

 


Cohort Study: Neurodevelopmental outcomes at 1 year in infants of mothers who tested positive for SARS-CoV-2 during pregnancy.

10 Jun, 2022 | 12:14h | UTC

Neurodevelopmental Outcomes at 1 Year in Infants of Mothers Who Tested Positive for SARS-CoV-2 During Pregnancy – JAMA Network Open

Commentaries:

Is It Exposure to the Pandemic or to Maternal SARS-CoV-2 Infection That Is Adversely Affecting Early Childhood Neurodevelopment? – JAMA Network Open

Expert reaction to observational study of mothers who tested positive for SARS-CoV-2 during pregnancy and neurodevelopmental outcomes in their children at 1 year – Science Media Centre

 

Commentary on Twitter

 


RCT: Effect of point-of-care testing for respiratory pathogens on antibiotic use in children.

10 Jun, 2022 | 11:16h | UTC

Effect of Point-of-Care Testing for Respiratory Pathogens on Antibiotic Use in Children: A Randomized Clinical Trial – JAMA Network Open

 

Commentary on Twitter

 


Unintended consequences of measures implemented in the school setting to contain the COVID‐19 pandemic: a scoping review.

7 Jun, 2022 | 11:41h | UTC

Unintended consequences of measures implemented in the school setting to contain the COVID‐19 pandemic: a scoping review – Cochrane Library

Summary: Unintended consequences of school-based measures to manage the COVID-19 pandemic – Cochrane Library

 


Stay Updated in Your Specialty

Telegram Channels
Free

WhatsApp alerts 10-day free trial

No spam, just news.