Neurology
Population-based cohort study: Youngest children in class are more likely to be diagnosed with a learning disability
11 May, 2021 | 09:08h | UTCCommentary: Youngest children in class are more likely to be diagnosed with a learning disability – University of Turku
Guideline: Diagnosis and treatment of neurogenic dysphagia.
6 May, 2021 | 08:51h | UTC
Management of the Patient With Patent Foramen Ovale in 2021: A Spectrum of Cases
5 May, 2021 | 08:15h | UTC
[Preprint] Frequency of neurological manifestations in COVID-19: a systematic review and meta-analysis of 350 studies – up to one-third of COVID-19 patients analyzed in this review, 89% of whom were hospitalized, experienced at least one neurological manifestation
4 May, 2021 | 08:44h | UTCCommentary: Study finds one-third of COVID-19 patients experience neurological symptoms – News Medical
M-A: A third of kids develop a mental health problem after concussion
4 May, 2021 | 08:35h | UTCNews Release: A third of kids develop a mental health problem after concussion – Murdoch Childrens Research Institute
Original Study: Mental health after paediatric concussion: a systematic review and meta-analysis – British Journal of Sports Medicine
Review: Parkinson’s disease
4 May, 2021 | 08:28h | UTCParkinson’s disease – The Lancet
Cohort Study: The risk of overdose with concomitant use of Z-Drugs (zolpidem, zopiclone, zaleplon) and prescription opioids is significantly increased
30 Apr, 2021 | 08:32h | UTCThe Risk of Overdose With Concomitant Use of Z-Drugs and Prescription Opioids: A Population-Based Cohort Study – American Journal of Psychiatry (link to abstract – $ for full-text)
Commentary: Co-prescribing Opioids, Z-Drugs May Increase Risk of Overdose – Psychiatric News Alert
AHA/ASA Guidance: Diagnosis and Management of Cerebral Venous Sinus Thrombosis with Vaccine-Induced Thrombotic Thrombocytopenia – “No heparin products in any dose should be given.”
30 Apr, 2021 | 08:25h | UTCNews release: Guidance on treatment for rare blood clots and low platelets related to COVID-19 vaccine – American Heart Association
COVID-19 ‘brain fog’ inspires search for causes and treatments
30 Apr, 2021 | 08:13h | UTCCOVID-19 ‘brain fog’ inspires search for causes and treatments – Science (a few articles per month are free)
Clinical Manifestation, Evaluation, and Rehabilitative Strategy of Dysphagia Associated With COVID-19
27 Apr, 2021 | 08:29h | UTC
Clinical review of 43 patients with COVID-19-associated Acute Transverse Myelitis and 3 patients with Acute Transverse Myelitis reported post-vaccination
27 Apr, 2021 | 08:32h | UTCCommentary: Rare neurological condition linked to COVID-19 cases in 21 countries – Houston Methodist
SARS-CoV-2 and Stroke Characteristics – higher rate of large vessel occlusions and stroke in young patients
25 Apr, 2021 | 22:01h | UTC
Commentary on Twitter
SARS-CoV-2 and #Stroke Characteristics: A Report From the Multinational COVID-19 Stroke Study Group #COVID19 #AHACOVID19 #AHAJournals @cgriessenauer @ArKatsanos https://t.co/Errp6MjQMV pic.twitter.com/QX5tAGQOXU
— Stroke AHA/ASA (@StrokeAHA_ASA) April 21, 2021
RCT: Promising results with vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischemic stroke
25 Apr, 2021 | 21:10h | UTCCommentary: Vagus nerve stimulation: a potential new treatment for ischaemic stroke – The Lancet
Commentary on Twitter
Very important @TheLancet study showing #vagus nerve stimulation improves rehabilitation ischemic #stroke.
Kudos Prof Jesse Dawson @UofGlasgow at colleagues!https://t.co/DsIH3wMuAp pic.twitter.com/QtzBBDVnso
— Prof Kevin J Tracey MD (@KevinJTraceyMD) April 23, 2021
Case series of 18 male adults aged 50 years or younger with acute ischemic stroke during the convalescent phase of asymptomatic Covid-19
23 Apr, 2021 | 08:39h | UTC
Commentary on Twitter
A ?? case series highlights that adults 50 years or younger with asymptomatic COVID-19 infection diagnosed by positive SARS-CoV-2 serological test result may present with ischemic stroke during the convalescent phase of the infection
https://t.co/BVlo7Z1hgn @JAMANetworkOpen— Antibiotic Steward??Bassam Ghanem (@ABsteward) April 22, 2021
Systematic review shows there is insufficient evidence on the best approaches to stop long‐term antidepressant use – “Future studies should distinguish carefully between relapse and withdrawal symptoms”
23 Apr, 2021 | 08:19h | UTCAuthor interview: Stopping long-term antidepressants in people with depression or anxiety – Cochrane Library
Commentary: ‘Urgent’ need for more evidence on safely stopping antidepressants, say experts – Metro
“Future studies should distinguish carefully between relapse and withdrawal symptoms and follow emerging guidance to use taper schemes of many weeks or months (or longer for long-term users) down to very low doses before stopping. Such studies would give us a clearer idea of the ability of antidepressants to prevent relapse.”
Commentary on Twitter (thread – click for more)
Outline of the Cochrane study a bit for those scared of its length. Metro article: https://t.co/3c32xjGJsr Lead author: the dauntless Ellen van Leuween. Co-author @tony_kendrick https://t.co/tt4Lzyacq4 While there are hundreds of studies looking at starting antidepressants(1/n)
— Mark Horowitz (@markhoro) April 22, 2021
Podcast: Dementia Made Simple
20 Apr, 2021 | 05:21h | UTC#268 Dementia Made Simple with Dr. Josh Uy – The Curbsiders
RCT: No benefit from second intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis
18 Apr, 2021 | 21:21h | UTCSecond intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis (SID-GBS): a double-blind, randomised, placebo-controlled trial – The Lancet Neurology (link to abstract – $ for full-text)
RCT: Comparison of Levetiracetam vs. Zonisamide vs. Lamotrigine for newly diagnosed focal epilepsy shows Lamotrigine should remain the first-line treatment option
12 Apr, 2021 | 00:51h | UTCCommentary: Clinical trials assess best first-line drugs for epilepsy – University of Liverpool
RCT: Comparison of Valproate vs. Levetiracetam for newly diagnosed generalized and unclassifiable epilepsy shows Valproate should remain the first-line treatment option
12 Apr, 2021 | 00:52h | UTCCommentary: Clinical trials assess best first-line drugs for epilepsy – University of Liverpool
AHA/ASA Scientific Statement: Perioperative Neurological Evaluation and Management to Lower the Risk of Acute Stroke in Patients Undergoing Noncardiac, Nonneurological Surgery
12 Apr, 2021 | 00:50h | UTC
Commentary on Twitter
NEW GUIDELINE – now codifies what has been discussed for a while "If history of stroke exists, consider delaying elective surgery at least 6 mo
and preferably 9 mo from time of incident stroke." @SPAQIedu @LeeAFleisher @preopconsult @afedwardMD https://t.co/0ewdlPGVlj— Kurt Pfeifer (@KurtPfeifer) April 9, 2021
Concussion in para sport: the first position statement of the Concussion in Para Sport (CIPS) Group
12 Apr, 2021 | 00:37h | UTC
Commentary on Twitter
The ink is still wet .. fresh out in @BJSM_BMJ. Para athletes suffer concussions too, but specific guidelines for care did not exist .. until now ‼️ Open access ➡️ https://t.co/ld1BENeoho pic.twitter.com/lkwsa8HsKd
— Evert Verhagen (@EvertVerhagen) April 10, 2021
RCT: Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy
9 Apr, 2021 | 03:18h | UTCAuthor Interview: Effect of High-Frequency (10 kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy
Commentary on Twitter
Thrilled to see our publication out today in @JAMANeuro using #SCS to treat #diabetic #pain. 86% of patients with over 50% pain relief at 6 months with better sleep and walking! #progress #needherscience #neuromodulation @UAMSneurosurg @UAMSPain @uamshealth https://t.co/TJQPHsHvSa
— Dr. Erika Petersen (@ErikaPetersenMD) April 5, 2021
NICE Guideline: Assessment and Management of Chronic Pain in Over 16s
8 Apr, 2021 | 08:54h | UTC
Large study finds 1 in 3 Covid-19 survivors have subsequent mental health and neurological conditions
8 Apr, 2021 | 09:14h | UTCCommentaries: 1 in 3 Covid-19 patients are diagnosed with a neuropsychiatric condition in the next six months, large study finds – STAT AND A longer look at COVID-19 and neuropsychiatric outcomes – The Lancet Psychiatry AND Largest study to date suggests link between COVID-19 infection and subsequent mental health and neurological conditions – The Lancet AND Covid-19: One in three has neurological or psychiatric condition diagnosed after covid infection, study finds – The BMJ AND One in three survivors of severe Covid diagnosed with mental health condition – The Guardian AND Covid-19 linked to depression and dementia, study suggests – BBC AND Expert reaction to observational study looking at neurological and psychiatric outcomes 6 months after COVID-19 – Science Media Centre AND 1 in 3 COVID Survivors Struggle With Mental Health Issues Months Later – HealthDay
Commentary on Twitter (thread – click for more)
?HUGE STUDY—One in 3 #COVID19 survivors received a neurological diagnosis within 6 months of infection—1 in 8 with first ever diagnosis, says study of 230,000 patient records. Also COVID patients had higher risk of dementia, anxiety, Parkinson’s vs flu.?https://t.co/BlhtUrOsvL pic.twitter.com/ZAcHZviGKR
— Eric Feigl-Ding (@DrEricDing) April 7, 2021
Cohort study: One in ten have long-term effects 8 months following mild COVID-19
8 Apr, 2021 | 09:12h | UTCOne in ten have long-term effects 8 months following mild COVID-19 – Karolinska Institutet
Original study: Symptoms and Functional Impairment Assessed 8 Months After Mild COVID-19 Among Health Care Workers – JAMA
Commentary on Twitter
#LongCovid in #Frontline: JAMA
Worrisome! N=323 COVID+ #Healthcare Workers vs. N=1072 w no COVID. At 8 mos, up to 4x risk of fxnl impairment in work, social & home life. REAL ongoing suffering in low-risk humans after #COVID.https://t.co/EwZWdW4ZtL#medtwitter #nurse pic.twitter.com/tofIx4p647— WesElyMD (@WesElyMD) April 7, 2021