Neurology
Cohort study: Risk of suicide attempt in patients with recent diagnosis of mild cognitive impairment or dementia
7 Apr, 2021 | 01:08h | UTCRisk of Suicide Attempt in Patients With Recent Diagnosis of Mild Cognitive Impairment or Dementia – JAMA Psychiatry (link to abstract – $ for full-text)
Commentaries: Recent Diagnosis of Cognitive Impairment, Dementia May Increase Suicide Risk – Psychiatric News Alert AND Suicide Attempts Spike Soon After Dementia Diagnosis – HealthDay
Exceedingly rare side effects reported with AstraZeneca vaccine in the UK – 22 cases of cerebral venous sinus thrombosis with low levels of platelets out of 18 million vaccinated individuals
5 Apr, 2021 | 01:45h | UTCCovid-19: Seven UK blood clot deaths after AstraZeneca vaccine – BBC
Original report: Coronavirus vaccine – weekly summary of Yellow Card reporting – Medicines and Healthcare products Regulatory Agency
Related opinion: Undermining the AstraZeneca jab is a dangerous act of political folly – The Guardian
“Based on current experience, the expected benefits of both COVID-19 vaccines in preventing COVID-19 and its serious complications far outweigh any known side effects”
M-A: Non-drug therapies as good as or better than drugs for treating depression in people with dementia
2 Apr, 2021 | 09:05h | UTCCommentaries: Non-drug therapies as good as or better than drugs for treating depression in people with dementia – The BMJ AND Social prescribing may help reduce symptoms of depression in people with dementia – The BMJ Opinion AND Nondrug Interventions Can Help Alleviate Depression in Dementia Patients – HealthDay
Long Covid in the UK – More than a million affected in February, survey suggests
2 Apr, 2021 | 09:31h | UTCLong Covid: More than a million affected in February, survey suggests – BBC
Commentary on Twitter
YOUNG ADULTS MOST AFFECTED—Long-Covid symptoms are affecting about 1.1 million people in the U.K., with about half that number saying the disease is harming their day-to-day lives, government statistics show. Top #LongCovid age group? 25-34! Thread ? https://t.co/Fwo8Opeqr6
— Eric Feigl-Ding (@DrEricDing) April 1, 2021
Study shows unique diagnostic signatures of concussion in the saliva of Rugby players
31 Mar, 2021 | 03:08h | UTCCommentaries: Concussion in sport: Saliva test is 94% accurate in rugby union trial – BBC AND Rugby study identifies new method to diagnose concussion using saliva – University of Birmingham AND Saliva test boosts efforts to detect concussions in rugby – Associated Press
COVID associated with hearing loss, tinnitus and vertigo – new study confirms link
30 Mar, 2021 | 03:19h | UTCOriginal study: One year on: an updated systematic review of SARS-CoV-2, COVID-19 and audio-vestibular symptoms – International Journal of Audiology
Long term outcomes of participants in the PARAMEDIC2 randomized trial of adrenaline in out-of-hospital cardiac arrest – although survival was improved, adrenalin was not associated with favorable neurologic outcomes
28 Mar, 2021 | 22:21h | UTCCommentary: PARAMEDIC2 – Epinephrine vs Placebo OHCA 6-12 Months – Journal Feed
Original study: Randomized Trial: Epinephrine in Out-of-Hospital Cardiac Arrest (study and commentaries) AND Opinion: Epinephrine Harms/Helps in Out of Hospital Cardiac Arrest
NICE Guideline Update: Cannabis-based medicinal products
28 Mar, 2021 | 22:24h | UTCCannabis-based medicinal products – National Institute for Health and Care Excellence
Choosing Wisely: Five things clinicians and patients should question in Neurological Surgery in Children
28 Mar, 2021 | 22:04h | UTCAmerican Academy of Pediatrics – Section on Neurological Surgery – Choosing Wisely
Commentary: Choosing Wisely: 5 Things to Avoid in Pediatric Neurologic Surgery – NEJM Journal Watch
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Covid-19: Middle aged women face greater risk of debilitating long term symptoms
28 Mar, 2021 | 22:49h | UTCCovid-19: Middle aged women face greater risk of debilitating long term symptoms – The BMJ
Linked Opinion: The stigma is real for people living with long covid – The BMJ Opinion
How COVID-19 Affects the Brain
28 Mar, 2021 | 22:51h | UTCHow COVID-19 Affects the Brain – JAMA Psychiatry
Commentary on Twitter
#COVID19 brain symptoms are a rising concern. Mechanisms of brain damage by the virus include lasting neuroinflammation, thrombotic events and alteration of neurotransmitters release. Consequently, people suffer cognitive, emotional and behavioral symptoms https://t.co/pTzJo6DLV8
— JAMA Psychiatry (@JAMAPsych) March 26, 2021
Persistent neurologic symptoms and cognitive dysfunction in non‐hospitalized Covid‐19 “long haulers”
28 Mar, 2021 | 22:48h | UTCCommentary: 85% of COVID-19 long-haulers have multiple brain-related symptoms – LiveScience AND ‘Brain fog’ and other neurologic symptoms can last for months after Covid – NBC News AND Neurologic Symptoms Persistent for Many COVID-19 ‘Long-Haulers’ – Health Day
RCT: Metoclopramide + diphenhydramine more efficacious than placebo for acute post-traumatic headache in the ED
26 Mar, 2021 | 08:24h | UTCRandomized Study of Metoclopramide Plus Diphenhydramine for Acute Posttraumatic Headache – Neurology (link to abstract – $ for full-text)
Commentary: Drug Combo Superior to Placebo for Posttraumatic Headache – HealthDay
RCT: Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc
25 Mar, 2021 | 08:12h | UTC
Commentary on Twitter
NEW RESEARCH—Surgical microdiscectomy and
transforaminal epidural steroid injection are similarly effective at reducing #pain and disability from #sciatica secondary to herniated lumbar disc https://t.co/xXOr1aOX8K #LancetRheumatology #OpenAccess pic.twitter.com/2CHh1YD2gm— The Lancet Rheumatology (@TheLancetRheum) March 19, 2021
RCT: Aspirin NOT noninferior to vitamin K antagonists in the treatment of cervical artery dissection
24 Mar, 2021 | 08:09h | UTCAspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial – The Lancet Neurology (link to abstract – $ for full-text)
Researchers identify head impact rates in four major high school sports
21 Mar, 2021 | 21:30h | UTCNews release: Researchers Identify Head Impact Rates in Four Major High School Sports – Children’s Hospital of Philadelphia
Original study: Sport- and Gender-Based Differences in Head Impact Exposure and Mechanism in High School Sports – Orthopaedic Journal of Sports Medicine
Commentary on Twitter
Excited to share our publication in @OJSM_SportsMed with @kristyarb and @drtinamaster! Male and female high school soccer had the highest head impact rate across four sports. Male teams also had higher impact rates than female teams of the same sport.https://t.co/eMOL925s04 https://t.co/elutojRfwJ
— Colin Huber (@Colin_M_Huber) March 18, 2021
Diagnosing and treating brain tumors: reflections on the latest Cochrane evidence
19 Mar, 2021 | 08:06h | UTC
M-A: Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments
19 Mar, 2021 | 07:52h | UTC
Review: Diagnosis and Management of Transient Ischemic Attack and Acute Ischemic Stroke
18 Mar, 2021 | 08:54h | UTCDiagnosis and Management of Transient Ischemic Attack and Acute Ischemic Stroke: A Review – JAMA
Five-year outcomes of PFO closure or antiplatelet therapy for cryptogenic stroke
17 Mar, 2021 | 02:40h | UTCPFO Closure for Stroke Is Safe, Effective at 5 Years: REDUCE – TCTMD
Original study: Five-Year Outcomes of PFO Closure or Antiplatelet Therapy for Cryptogenic Stroke – New England Journal of Medicine ($)
Imaging review of peripheral nerve injuries in patients with COVID-19
17 Mar, 2021 | 02:48h | UTCImaging Review of Peripheral Nerve Injuries in Patients with COVID-19 – Radiology
Consensus Statement on Analgo-sedation in Neurocritical Care and Review of Literature
17 Mar, 2021 | 02:09h | UTC
Central nervous system–active polypharmacy common among older adults with dementia in the US
16 Mar, 2021 | 01:45h | UTCPrevalence of Central Nervous System–Active Polypharmacy Among Older Adults With Dementia in the US – JAMA (free for a limited period)
Commentaries: CNS-Active Polypharmacy Examined in Seniors With Dementia – HealthDay AND A Trio That Could Spell Trouble: Many with Dementia Take Risky Combinations of Medicines – Michigan Medicine – University of Michigan AND Older Adults With Dementia at Risk From Taking Multiple Psychotropics, Study Suggests – Psychiatric News Alert
Commentary on Twitter
In this cross-sectional study of Medicare claims, 14% of older adults with dementia filled prescriptions consistent with CNS-active polypharmacy in 2018 (eg 3+ antidepressants, antipsychotics, BNZ, Z-drugs, or opioids) https://t.co/85BmGgeYil @dtmaust @umichmedicine @PennMedicine
— JAMA (@JAMA_current) March 9, 2021
Systematic Review: Encephalitis induced by immune checkpoint inhibitors
16 Mar, 2021 | 01:36h | UTCEncephalitis Induced by Immune Checkpoint Inhibitors: A Systematic Review – JAMA Neurology
Best practice recommendations for stroke patients with dysphagia
16 Mar, 2021 | 01:26h | UTC