Study suggests it is safe to discontinue antiseizure medication for most neonates with acute symptomatic seizures prior to discharge from the hospital.

Safety of Early Discontinuation of Antiseizure Medication After Acute Symptomatic Neonatal Seizures – JAMA Neurology (free for a limited period)

Editorial: Discontinuing Antiseizure Medication in Neonates With Acute Symptomatic Seizures—Primum non nocere – JAMA Neurology (free for a limited period)

Commentaries: Stopping Antiseizure Medication After Acute Symptomatic Neonatal Seizures Is Found to Be Safe – Neurology Today AND Babies with Seizures May Be Overmedicated – Michigan Medicine

Commentary on Twitter

New CER study on @JAMANeuro finds no difference in functional neurodevelopment or epilepsy at 24 mnths in children whose antiseizure meds was discont'd vs maintained at discharge after resolution of acute symptomatic neonatal seizures: https://t.co/yvKbrJuCvQ #ebneoalerts #neoEBM pic.twitter.com/810weSUSgb

— Evidence-Based Neo (@EBNEO) May 26, 2021