Neurology
Cohort study: Neurological manifestations of SARS-CoV-2 infection in hospitalized children and adolescents in the UK – “around 1 in 20 of children hospitalized with COVID-19 develop brain or nerve complications linked to the viral infection”.
26 Jul, 2021 | 02:58h | UTCCommentaries:
Commentary on Twitter
A UK national prospective study of brain involvement in children hospitalized with covid: wide range of neurologic complications in 51 kidshttps://t.co/4JvjbthgH4 @LancetChildAdol pic.twitter.com/IiXF9bVmKz
— Eric Topol (@EricTopol) July 14, 2021
Consensus Statement: Best practices in the clinical management of progressive supranuclear palsy and corticobasal syndrome.
23 Jul, 2021 | 10:22h | UTCCommentary: Treatment guide for neurodegenerative disorders – Johns Hopkins University
International Registry: Ischemic and hemorrhagic stroke among critically ill patients with Covid-19.
20 Jul, 2021 | 10:21h | UTCRelated: SARS-CoV-2 and Stroke Characteristics – higher rate of large vessel occlusions and stroke in young patients AND Case series of 18 male adults aged 50 years or younger with acute ischemic stroke during the convalescent phase of asymptomatic Covid-19 AND Case-control study: COVID-19-associated stroke is associated with worse outcomes and increased mortality AND Pictorial essay: Neurological emergencies associated with COVID-19: stroke and beyond AND Characteristics and Outcomes in Patients With COVID-19 and Acute Ischemic Stroke AND Risk of Ischemic Stroke in Patients with COVID-19 vs. Patients with Influenza
Systematic review: In hospitalized non‐ICU patients, multicomponent non-pharmacological interventions are estimated to reduce the incidence of delirium by 43% compared to usual care.
20 Jul, 2021 | 10:07h | UTC
Review: Parkinson disease-associated cognitive impairment.
18 Jul, 2021 | 23:17h | UTCParkinson disease-associated cognitive impairment – Nature Reviews Disease Primers (free for a limited period)
Infographic: Parkinson disease-associated cognitive impairment
AHA/ASA Scientific Statement: Primary Care of Adult Patients After Stroke.
18 Jul, 2021 | 23:20h | UTCNews release: Comprehensive primary care is vital to holistic care and optimal recovery after a stroke – American Heart Association
Commentary on Twitter
Primary Care of Adult Patients After Stroke: A Scientific Statement From the American Heart Association/American Stroke Association https://t.co/moIZ1W2cXL @American_Heart @American_Stroke pic.twitter.com/jWOK8Fz0vM
— Stroke AHA/ASA (@StrokeAHA_ASA) July 15, 2021
Review: Sedation in the Intensive Care Unit.
16 Jul, 2021 | 10:31h | UTCSedation in the Intensive Care Unit – Current Anesthesiology Reports
RCT: Effect of neurofeedback facilitation on poststroke gait and balance recovery.
16 Jul, 2021 | 10:30h | UTCCommentary: Neurofeedback Facilitation Improves Gait and Balance in Post-Stroke Patients – BrainPost
COVID and the brain: researchers zero in on how damage occurs.
15 Jul, 2021 | 09:18h | UTCCOVID and the brain: researchers zero in on how damage occurs – Nature
[Preprint] Brain imaging before and after COVID-19 in UK Biobank.
15 Jul, 2021 | 09:17h | UTCBrain imaging before and after COVID-19 in UK Biobank – medRxiv
Commentaries: COVID linked to loss of brain tissue: but correlation doesn’t prove causation – The Conversation AND COVID-19 survivors may suffer from a loss of gray matter and other brain tissue over time, a long-term study suggests – Business Insider
Tramadol: Where do we go from here? – “Tramadol’s unpredictability, unique potential harms, and lack of advantage over other opioids or NSAIDs are now well recognized”.
15 Jul, 2021 | 09:14h | UTC[131] Tramadol: Where do we go from here? – Therapeutic Initiative
M-A: Utility of intravenous Alteplase prior to endovascular stroke treatment.
15 Jul, 2021 | 09:03h | UTCUtility of Intravenous Alteplase Prior to Endovascular Stroke Treatment: A Systematic Review and Meta-analysis of RCTs – Neurology (link to abstract – $ for full-text)
Commentary: Direct thrombectomy, bridging therapy confer similar functional outcomes in stroke – Healio (free registration required)
Commentary on Twitter
Via @GreenJournal: For #patients with acute large vessel occlusion, functional outcomes were similar for those receiving direct #endovascular treatment and bridging therapy.#NeuroTwitter #neurology https://t.co/LweNGwOhVB pic.twitter.com/jqgZyV9ZOA
— Neurology Today (@NeurologyToday) June 22, 2021
Extremely rare cases of Guillain-Barré reported with Johnson & Johnson vaccine for Covid-19.
13 Jul, 2021 | 09:48h | UTCJ&J’s Covid-19 vaccine may trigger neurological condition in rare cases, FDA says – STAT
See also: Johnson & Johnson Vaccine Is Linked To Neurological Disorder In Extremely Rare Cases – NPR AND F.D.A. Attaches Warning of Rare Nerve Syndrome to Johnson & Johnson Vaccine – The New York Times
Review: Infectious disease-associated encephalopathies.
13 Jul, 2021 | 09:30h | UTCInfectious disease-associated encephalopathies – Critical Care
Commentary on Twitter
A Review published in Critical Care focuses on the pathophysiology of encephalopathies associated with sepsis, malaria, influenza, and COVID-19; emerging therapeutic strategies; and the role of neuroinflammation. https://t.co/991S4kAKJk
— BMC (@BioMedCentral) July 11, 2021
Editorial: Aducanumab for Alzheimer’s disease?
12 Jul, 2021 | 01:15h | UTCAducanumab for Alzheimer’s disease? – The BMJ
Related: FDA approvement of Alzheimer’s drug sparks controversy among doctors.
Commentary on Twitter
Our editorial for @bmj_latest on the controversial #Aducanumab approval and what it means for patients, clinicians and researchers.
With @seb_walsh, Richard Milne @ethicsWCS, Carol Brayne @CamPubHealth https://t.co/mnhh4F1gKK— Richard Merrick (@r_merrick) July 9, 2021
Systematic review: Prophylactic drug management for febrile seizures in children.
9 Jul, 2021 | 09:51h | UTCProphylactic drug management for febrile seizures in children – Cochrane Library
Summary: Prophylactic drug management for febrile seizures in children
Systematic review: Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure.
8 Jul, 2021 | 08:48h | UTC
RCT: Consuming a diet with more fish fats, less vegetable oils can reduce migraine headaches.
5 Jul, 2021 | 01:51h | UTCNews release: Consuming a diet with more fish fats, less vegetable oils can reduce migraine headaches – NIH News Releases
Original study: Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial – The BMJ
Editorial: Dietary omega 3 fatty acids for migraine
RCT: Safety and efficacy of occipital nerve stimulation for attack prevention in medically intractable chronic cluster headache.
5 Jul, 2021 | 01:24h | UTCSafety and efficacy of occipital nerve stimulation for attack prevention in medically intractable chronic cluster headache (ICON): a randomised, double-blind, multicentre, phase 3, electrical dose-controlled trial – The Lancet Neurology (link to abstract – $ for full-text)
Commentary: Nerve stimulation effective in patients with untreatable cluster headaches – Leiden University
Complex Regional Pain Syndrome: A Comprehensive Review
2 Jul, 2021 | 11:13h | UTCComplex Regional Pain Syndrome: A Comprehensive Review – Pain and Therapy
The Management of Restless Legs Syndrome: An Updated Algorithm
2 Jul, 2021 | 11:12h | UTCThe Management of Restless Legs Syndrome: An Updated Algorithm – Mayo Clinic Proceedings
The neurological manifestations of post-acute sequelae of SARS-CoV-2 infection.
1 Jul, 2021 | 09:55h | UTC
Long COVID or post-acute sequelae of COVID-19 (PASC): An overview of biological factors that may contribute to persistent symptoms.
30 Jun, 2021 | 10:24h | UTC
Study finds 96.1% of patients objectively recovered from anosmia 1 year after COVID-19 diagnosis.
28 Jun, 2021 | 09:49h | UTCClinical Outcomes for Patients With Anosmia 1 Year After COVID-19 Diagnosis – JAMA Network Open
Commentary: Did Covid-19 take your taste and smell? Here’s when they may return – CNN AND Lost Sense of Smell Returns for Almost All COVID Survivors – HealthDay
Long Covid: Half of young adults with COVID-19 have persistent symptoms 6 months after, study finds.
25 Jun, 2021 | 10:33h | UTCOriginal Study: Long COVID in a prospective cohort of home-isolated patients – Nature Medicine
Commentary on Twitter
Analysis of a prospectively enrolled cohort of patients with #SARSCoV2 infections reveals a high proportion who experienced #LongCovid symptoms at 6 months, despite being relatively young and having only mild to moderate acute #COVID19 symptoms https://t.co/fuW2QpfJog
— Nature Medicine (@NatureMedicine) June 23, 2021