Neurology
Cohort Study: Long-term cannabis use is associated with cognitive deficits and smaller hippocampal volume in midlife.
14 Mar, 2022 | 01:31h | UTCLong-Term Cannabis Use and Cognitive Reserves and Hippocampal Volume in Midlife – The American Journal of Psychiatry (link to abstract – $ for full-text)
Commentary: Long-Term Cannabis Use Associated With Cognitive Deficits in Midlife – Psychiatric News Alert
RCT: Safety and efficacy of three enteral feeding strategies in patients with severe stroke.
11 Mar, 2022 | 09:51h | UTCSafety and efficacy of three enteral feeding strategies in patients with severe stroke in China (OPENS): a multicentre, prospective, randomised, open-label, blinded-endpoint trial – The Lancet Neurology (link to abstract – $ for full-text)
Perspective: What do we know about Covid’s impact on the brain?
10 Mar, 2022 | 10:46h | UTCWhat do we know about Covid’s impact on the brain? – The Guardian
Related: SARS-CoV-2 is associated with changes in brain structure in UK Biobank.
AAN Position Statement: Clinical guidance in neuropalliative care.
9 Mar, 2022 | 09:56h | UTCClinical Guidance in Neuropalliative Care: An AAN Position Statement – Neurology
Cohort Study: One-year trajectory of cognitive changes in older survivors of COVID-19 in Wuhan, China.
9 Mar, 2022 | 09:51h | UTC
SARS-CoV-2 is associated with changes in brain structure in UK Biobank.
9 Mar, 2022 | 09:53h | UTCSARS-CoV-2 is associated with changes in brain structure in UK Biobank – Nature
Commentary:
Brain changes after COVID revealed by imaging – Nature
Scans reveal how Covid may change the brain – BBC
Review: Pathophysiology and clinical features of neuropsychiatric manifestations of thyroid disease.
9 Mar, 2022 | 08:25h | UTC
Associations between alcohol consumption and gray and white matter volumes in the UK Biobank.
8 Mar, 2022 | 08:31h | UTCCommentaries:
Just one drink per day can shrink your brain, study says – CNN
Systematic Review: Prediction of good neurological outcome in comatose survivors of cardiac arrest.
7 Mar, 2022 | 00:40h | UTC
Commentary on Twitter
Predicting good neuro outcome in comatose cardiac arrest survivors? Look at
🧠 GCS motor 4/5
🧠 normal NSE
🧠 SSEP N20 wave amplitude > 4 μV or continuous EEG background without discharges
🧠 no diffusion restriction in cortex or deep grey matter on MRI
SR https://t.co/ixkMvErdux pic.twitter.com/GjeuTLgDlb— Intensive Care Medicine (@yourICM) March 4, 2022
Distribution of delirium motor subtypes in the intensive care unit: a systematic scoping review.
6 Mar, 2022 | 23:38h | UTC
Cohort Study: Association between screen time exposure in children at 1 year of age and autism spectrum disorder at 3 years of age.
4 Mar, 2022 | 09:54h | UTCCommentary: Screen Time Linked to Autism Spectrum Disorder in Boys – HealthDay
Related:
M-A: Global prevalence of meeting screen time guidelines among children 5 years and younger.
Media and Young Minds – American Academy of Pediatrics
Association between incident cancer and Guillain-barré syndrome development: a nationwide case-control study.
4 Mar, 2022 | 08:33h | UTCAssociation Between Incident Cancer and Guillain-Barré Syndrome Development: A Nationwide Case-Control Study – Neurology (link to abstract – $ for full-text)
News Release: Certain Types of Cancer May Increase the Risk of Developing Guillain-Barré – American Academy of Neurology
RCT: Aspirin and unfractionated heparin increase the risk of symptomatic intracranial hemorrhage in patients undergoing endovascular treatment for ischemic stroke.
3 Mar, 2022 | 08:53h | UTCSafety and efficacy of aspirin, unfractionated heparin, both, or neither during endovascular stroke treatment (MR CLEAN-MED): an open-label, multicentre, randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Postcraniotomy Headache: Etiologies and treatments.
3 Mar, 2022 | 07:55h | UTCPostcraniotomy Headache: Etiologies and Treatments – Current Pain and Headache Reports
RCT: Prophylactic melatonin does not reduce the incidence of delirium in intensive care patients.
1 Mar, 2022 | 08:45h | UTCProphylactic melatonin for delirium in intensive care (Pro-MEDIC): a randomized controlled trial – Intensive Care Medicine (link to abstract – $ for full-text)
Commentaries on Twitter
Enteral prophylactic melatonin initiated early (within 48h of admission) & continued throughout #ICU (MAX 14 consecutive days) do not ⬇️#delirium prevalence vs placebo, Pro-MEDIC multicentre RCT
➡️12🇦🇺ICUs
➡️841 pts
➡️delirium-free assessments 79.2% vs 80%https://t.co/Gt5o1VuRo7 pic.twitter.com/gPRWxxmhHS— Intensive Care Medicine (@yourICM) February 28, 2022
In 841 ICU patients with expected stay >72h, 4 mg melatonin within 48h after admission for 14 days vs placebo made no sign. differences in delirium-free assessments, LoS, 90d mortality, nor quality & quantity of sleep
Good bye Melatonin, we had a good timehttps://t.co/d0dayil99W— Peter Nydahl (@NydahlPeter) February 28, 2022
RCT: A mindfulness-oriented intervention may reduce opioid misuse and chronic pain in primary care.
1 Mar, 2022 | 08:32h | UTCMindfulness-Oriented Recovery Enhancement vs Supportive Group Therapy for Co-occurring Opioid Misuse and Chronic Pain in Primary Care: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Mindfulness-Based Intervention Found to Reduce Chronic Pain and Opioid Misuse – Psychiatric News Alert
Commentary on Twitter
A randomized clinical trial showed that #Mindfulness-Oriented Recovery Enhancement delivered in the primary care setting reduces opioid misuse by as much as 46%, while simultaneously reducing chronic pain and emotional distress. https://t.co/eNj42RBCRA @DrEricGarland pic.twitter.com/tBatMT9lkQ
— JAMA Internal Medicine (@JAMAInternalMed) February 28, 2022
Review: New generation psychological treatments in chronic pain.
1 Mar, 2022 | 08:41h | UTCNew generation psychological treatments in chronic pain – The BMJ (free for a limited period)
Meta-analysis suggests there is low risk of delayed intracranial hemorrhage (after a negative initial head CT) following low energy blunt head trauma while on direct oral anticoagulants.
27 Feb, 2022 | 22:30h | UTC
RCT: In comatose survivors of cardiac arrest, a strategy of suppressing rhythmic and periodic EEG activity with the use of antiseizure medication did not improve neurologic outcomes.
24 Feb, 2022 | 10:45h | UTCTreating Rhythmic and Periodic EEG Patterns in Comatose Survivors of Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
In trial of comatose patients after cardiac arrest, intensive antiseizure treatment adapted from protocols for status epilepticus did not result in fewer poor outcomes at 3 mos than standard treatment. https://t.co/dpH5cgwhvW pic.twitter.com/zVBHBYMRK9
— NEJM (@NEJM) February 23, 2022
RCT: Sublingual dexmedetomidine reduces mild to moderate acute agitation in patients with bipolar disorder.
23 Feb, 2022 | 10:18h | UTCEffect of Sublingual Dexmedetomidine vs Placebo on Acute Agitation Associated With Bipolar Disorder: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Sublingual Dexmedetomidine as a Potential New Treatment for Agitation – JAMA (free for a limited period)
Commentary on Twitter
Randomized clinical trial found sublingual #dexmedetomidine at a dose of 180 μg or 120 μg reduced mild to moderate agitation in patients with #bipolar disorder. https://t.co/1VK2e15F7s pic.twitter.com/0oHw6eVMIP
— JAMA (@JAMA_current) February 22, 2022
M-A: Combining antidepressants vs. antidepressant monotherapy for treatment of patients with acute depression.
22 Feb, 2022 | 08:40h | UTCCombining Antidepressants vs Antidepressant Monotherapy for Treatment of Patients With Acute Depression: A Systematic Review and Meta-analysis – JAMA Psychiatry (free for a limited period)
M-A of randomized trials | Association between intensity of LDL cholesterol reduction with statin-based therapies and secondary stroke prevention.
22 Feb, 2022 | 08:37h | UTCEditorial: Low-Density Lipoprotein Cholesterol Level After a Stroke—Reducing It by Any Means (free for a limited period)
Early and late-onset syncope: insight into mechanisms.
22 Feb, 2022 | 08:29h | UTCEarly and late-onset syncope: insight into mechanisms – European Heart Journal
Commentary on Twitter
Early and late-onset syncope: insight into mechanisms https://t.co/OlAT50jIt8 @escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/F2gzBH9X2i
— European Society of Cardiology Journals (@ESC_Journals) February 17, 2022
Review: Acute ischemic stroke and its challenges for the intensivist.
22 Feb, 2022 | 08:27h | UTC
Review | Acute traumatic brain injury in frail patients: the next pandemic.
21 Feb, 2022 | 08:31h | UTCAcute traumatic brain injury in frail patients: the next pandemic – Current Opinion in Critical Care


