RCT: In comatose survivors of cardiac arrest, a strategy of suppressing rhythmic and periodic EEG activity with the use of antiseizure medication did not improve neurologic outcomes.

Treating Rhythmic and Periodic EEG Patterns in Comatose Survivors of Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary on Twitter

In trial of comatose patients after cardiac arrest, intensive antiseizure treatment adapted from protocols for status epilepticus did not result in fewer poor outcomes at 3 mos than standard treatment. https://t.co/dpH5cgwhvW pic.twitter.com/zVBHBYMRK9

— NEJM (@NEJM) February 23, 2022