Internal Medicine
Randomized crossover study shows regular use of Paracetamol increases systolic blood pressure by approximately 5 mm Hg when compared with placebo in hypertensive individuals.
8 Feb, 2022 | 10:11h | UTCRegular Acetaminophen Use and Blood Pressure in People With Hypertension: The PATH-BP Trial – Circulation (link to abstract – $ for full-text)
Commentaries:
Regular paracetamol use linked to higher blood pressure, study finds – University of Edinburg
Blood pressure warning over long-term paracetamol use – BBC
COVID-19 infections increase risk of heart conditions up to a year later, study finds.
8 Feb, 2022 | 10:15h | UTCNews Release: COVID-19 infections increase risk of heart conditions up to a year later, study finds – Washington University in St. Louis
Original Study: Long-term cardiovascular outcomes of COVID-19 – Nature Medicine
Rapid control of hospital-based SARS-CoV-2 Omicron clusters through daily testing and universal use of N95 respirators.
8 Feb, 2022 | 10:09h | UTC
Expert panel consensus on management of advanced cancer–related pain in individuals with opioid use disorder.
8 Feb, 2022 | 08:49h | UTCCommentaries:
Guidance Offered for Managing Pain in Patients With Cancer and OUD – HealthDay
AASLD Practice Guidance: Palliative care and symptom-based management in decompensated cirrhosis.
8 Feb, 2022 | 08:51h | UTCRelated: Meta-Analysis: Symptom Prevalence and Quality of Life of Patients with End-stage Liver Disease
Practice guidelines for office and out-of-office blood pressure measurement.
8 Feb, 2022 | 10:02h | UTC
In patients taking anticoagulants (DOAC or Warfarin), a respiratory tract infection not treated with antibiotics is associated with a greater than twofold increase in the risk of bleeding during the next 0-14 days.
8 Feb, 2022 | 08:46h | UTC
Commentary on Twitter
In new research of 1208 oral anticoagulant users, a greater than twofold increase was seen in the risk of major bleeding & clinically relevant non-major bleeding in the 0-14 days after a respiratory tract infection for which no antibiotics were prescribed https://t.co/wMIb2eDBKk
— The BMJ (@bmj_latest) December 21, 2021
Gamma-Glutamyl Transferase (γ-GT) – an old dog with new tricks?
8 Feb, 2022 | 08:35h | UTCGamma-Glutamyl Transferase (γ-GT) – an old dog with new tricks? – Liver International
Cluster-Randomized Trial: A multicomponent diagnostic strategy (on-site molecular testing for tuberculosis, guided restructuring of clinic workflows, and monthly feedback of quality metrics) significantly improved the rates of a confirmed diagnosis of tuberculosis within 14 days after presentation.
8 Feb, 2022 | 08:43h | UTCMulticomponent Strategy with Decentralized Molecular Testing for Tuberculosis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
A cluster-randomized trial in 20 Ugandan health centers compared a multicomponent TB strategy with routine care. The intervention led to greater numbers of patients being tested for, receiving a diagnosis of, and being treated for confirmed TB. https://t.co/PcJDC1I0CY pic.twitter.com/AT99QVOn2S
— NEJM (@NEJM) December 28, 2021
Podcast: Palpitation Pearls.
8 Feb, 2022 | 08:34h | UTC#320 Palpitations with Dr. Joshua Cooper – The Curbsiders
Clinical update on COVID-19 for the emergency clinician: Presentation and evaluation.
7 Feb, 2022 | 08:56h | UTC
EULAR recommendations for cardiovascular risk management in rheumatic and musculoskeletal diseases, including systemic lupus erythematosus and antiphospholipid syndrome.
7 Feb, 2022 | 08:43h | UTC
A highly virulent variant of HIV-1 circulating in the Netherlands.
7 Feb, 2022 | 08:42h | UTCA highly virulent variant of HIV-1 circulating in the Netherlands – Science
Commentaries:
New highly virulent and damaging HIV variant discovered in the Netherlands – University of Oxford
Highly virulent HIV variant found circulating in Europe – Nature
Guideline: Management and follow-up of gallbladder polyps – “If the patient has no risk factors for malignancy, and a gallbladder polypoid lesion of 5 mm or less, follow-up is not required”.
7 Feb, 2022 | 08:39h | UTC
Patent Foramen Ovale (PFO) After Stroke: Meta-analysis suggests the application of a multivariable causal classification system may better distinguish patient subgroups who may benefit from PFO closure from those unlikely to receive benefit.
7 Feb, 2022 | 08:31h | UTCHeterogeneity of Treatment Effects in an Analysis of Pooled Individual Patient Data From Randomized Trials of Device Closure of Patent Foramen Ovale After Stroke – JAMA (link to abstract – $ for full-text)
Commentary: Classification System May Identify Patients Likely to Benefit from PFO Closure – Physician’s Weekly
Related:
Management of the Patient With Patent Foramen Ovale in 2021: A Spectrum of Cases
Commentary on Twitter
Analysis of individual patient data from RCTs found application of a multivariable causal classification system to randomized trial results that distinguished subgroups who may benefit from patent foramen ovale (PFO) closure vs those unlikely to benefit https://t.co/L9Ic9EsNPG
— JAMA (@JAMA_current) December 15, 2021
Summary: 2021 CDC guidelines on sexually transmitted infections.
7 Feb, 2022 | 08:33h | UTC2021 CDC guidelines on sexually transmitted infections – Family Medicine
Original Guideline: CDC releases new guidelines for the treatment of sexually transmitted infections.
Related: WHO Guidelines for the management of symptomatic sexually transmitted infections.
Review: Post-transplant cardiovascular disease.
7 Feb, 2022 | 08:20h | UTCPost-Transplant Cardiovascular Disease – Clinical Journal of the American Society of Nephrology
Review: video-based telemedicine for kidney disease care.
7 Feb, 2022 | 08:22h | UTCPatient Voice: Patient Views on Telehealth for Kidney Disease Care – Clinical Journal of the American Society of Nephrology
The kidney in normal aging: a comparison with chronic kidney disease.
7 Feb, 2022 | 08:18h | UTC
A cohort study including 11 US hospitals and 232 patients with Vancomycin-resistant enterococci (VRE) showed an 18% mortality rate; failure of early eradication of VRE from the bloodstream was the strongest predictor of in-hospital mortality.
7 Feb, 2022 | 08:12h | UTC
Commentary on Twitter
New in OFID: In a prospective cohort with enterococcal bloodstream infections, failure to eradicate vancomycin-resistant enterococci from the bloodstream early was a major factor associated with poor outcomes.
📄 https://t.co/I4hlelW2La@PaulSaxMD @DrJLi @FungalDoc @SuperBugDoc pic.twitter.com/m10YeVjUXw
— IDSA (@IDSAInfo) January 1, 2022
RCT: Ketamine is a short-term effective treatment for some suicidal patients in hospital.
4 Feb, 2022 | 10:05h | UTCNews Release: Ketamine is a short-term effective treatment for some suicidal patients in hospital – BMJ
Original Article: Ketamine for the acute treatment of severe suicidal ideation: double blind, randomised placebo controlled trial – The BMJ
Editorial: Ketamine for suicidal ideation – The BMJ
Related:
Systematic Review: Ketamine for the treatment of mental health and substance use disorders.
Randomized trial: Repeated Ketamine administration for chronic posttraumatic stress disorder
Ketamine and Depression: A Narrative Review
Does my hospitalized patient need an NPO-after-midnight order preoperatively?
4 Feb, 2022 | 09:58h | UTCRelated:
Pro-Con Debate: 1- vs 2-Hour Fast for Clear Liquids Before Anesthesia in Children.
Consensus Statement: Preoperative Management of Medications for Neurologic Diseases.
4 Feb, 2022 | 10:00h | UTCPreoperative Management of Medications for Neurologic Diseases – Mayo Clinic Proceedings
Related: Consensus Statement: Preoperative management of medications for psychiatric diseases.
2022 ACR/EULAR classification criteria for microscopic polyangiitis.
4 Feb, 2022 | 09:54h | UTC2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for microscopic polyangiitis – Annals of Rheumatic Diseases (link to abstract – $ for full-text)
Commentary on Twitter
🚨 # 2022 ACR/EULAR classification criteria for Rheumatology classification criteria for microscopic polyangiitis
1️⃣sensitivity 91%
2️⃣specificity 94%https://t.co/6pPHL8JGVH pic.twitter.com/NJdrS9c6gs— Annals of the Rheumatic Diseases (@eular_ARD) February 2, 2022
2022 ACR/EULAR Classification Criteria for Eosinophilic Granulomatosis with Polyangiitis.
4 Feb, 2022 | 08:57h | UTC2022 American College of Rheumatology/European Alliance of Associations for Rheumatology Classification Criteria for Eosinophilic Granulomatosis with Polyangiitis – Annals of Rheumatic Diseases (link to abstract – $ for full-text)
Commentary on Twitter
🚨 # 2022 ACR/EULAR classification criteria for Eosinophilic Granulomatosis with Polyangiitis
1️⃣ sensitivity 85%
2️⃣ specificity 99%https://t.co/WWNk6n8Q09 pic.twitter.com/y41VnP39P7— Annals of the Rheumatic Diseases (@eular_ARD) February 2, 2022